Best TWAS P=1.41e-07 · Best GWAS P=1.26e-07 conditioned to 0.0485
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | PSMG1 | 0.14 | 0.09 | lasso | 11 | 0.07 | 0.00327 | -4.8 | 5.2 | 2.1e-07 | 0.64 | 0.05 | 0.82 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | BRWD1 | 0.09 | 0.05 | lasso | 8 | 0.04 | 0.00049 | -4.7 | 5.2 | 1.7e-07 | 0.58 | 0.04 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PSMG1 | 0.07 | 0.07 | blup | 61 | 0.04 | 0.00631 | -5.0 | 5.3 | 1.4e-07 | 0.76 | 0.01 | 0.88 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | PSMG1 | 0.07 | 0.04 | blup | 61 | 0.06 | 0.00174 | -2.7 | 5.2 | 2.3e-07 | 0.71 | 0.02 | 0.86 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | BRWD1 | 0.04 | 0.02 | blup | 97 | 0.03 | 0.00229 | -2.8 | 5.2 | 2.5e-07 | 0.63 | 0.04 | 0.54 | FALSE |