Hub : Genes

BRWD1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1180	0.0250	1.4e-12	0.147	0.118	0.143	0.135	0.149	1.9e-17	3.8e-14	5.3e-17	4.1e-16	1.1e-17
2	GTEx	Nerve Tibial	0.1662	0.0490	1.8e-04	0.011	NA	0.026	NA	0.028	5.0e-02	NA	5.9e-03	NA	4.6e-03
3	GTEx	Skin Sun Exposed Lower leg	0.0860	0.0340	2.6e-03	0.046	NA	0.014	NA	0.037	9.8e-05	NA	2.4e-02	NA	4.9e-04
4	GTEx	Vagina	0.4080	0.1170	7.0e-03	0.096	NA	0.060	NA	0.064	3.3e-03	NA	1.8e-02	NA	1.4e-02
5	METSIM	Adipose	0.0465	0.0206	9.0e-03	-0.002	0.008	-0.002	0.008	-0.002	7.7e-01	1.8e-02	7.8e-01	2.0e-02	7.2e-01
6	YFS	Blood	0.3419	0.0296	0.0e+00	0.496	0.507	0.519	0.510	0.516	8.5e-190	5.6e-196	1.3e-202	1.4e-197	6.0e-201
7	TCGA	Brain Lower Grade Glioma	0.1108	0.0684	5.8e-03	0.028	0.029	0.032	NA	0.032	3.0e-04	2.5e-04	1.5e-04	NA	1.5e-04
8	TCGA	Soft Tissue Sarcoma	0.4270	0.1540	1.2e-03	0.014	0.051	0.057	NA	0.027	4.5e-02	5.4e-04	2.6e-04	NA	9.2e-03
9	TCGA	Stomach Adenocarcinoma	0.0410	0.0260	4.1e-03	0.025	0.032	0.022	NA	0.028	6.0e-03	2.3e-03	9.8e-03	NA	3.7e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.9	1.4	4.6	1.3	0.5	1.5	0.5	-2.1	0.4	1.0	0.7	1.2
Bipolar Disorder or Schizophrenia	1.4	3.3	7.3	2.4	1.8	2.7	-0.5	-1.4	1.7	1.1	1.6	2.1
Depressed Affect (Nagel 2018)	0.4	0.8	4.1	-0.8	-0.4	-0.1	-2.0	-0.3	-0.7	-0.6	0.5	-0.9
Depression (Nagel 2018)	0.7	1.0	6.0	-0.2	-0.7	0.2	-2.5	-0.0	-0.9	-0.2	1.2	-0.1
Intelligence (Savage-Jansen 2018)	6.1	18.7	42.4	-6.1	-5.3	-6.5	-1.3	1.1	-3.1	-3.4	-1.4	-5.9
Neuroticism (Nagel 2018)	0.8	2.0	4.4	-1.6	-1.3	-0.7	-2.1	-0.0	-1.2	-2.0	0.4	-1.8
Schizophrenia (2018)	1.2	2.6	4.9	2.1	2.0	2.2	-1.0	-0.0	1.9	0.5	1.5	1.7
Schizophrenia vs Biploar Disorder	0.1	0.2	0.6	-0.1	0.6	0.1	0.4	0.4	0.3	-0.1	0.8	-0.4
Worry (Nagel 2018)	0.4	0.8	2.9	-0.7	-0.9	0.4	-1.7	0.4	0.2	-1.5	-0.2	-0.5
Alzheimer’s Disease (in mother)	0.5	0.6	1.2	0.8	1.1	1.1	0.3	-0.7	0.4	0.1	1.1	0.7
Alzheimer’s Disease (in father)	1.0	1.1	2.7	-0.2	-0.1	-1.5	1.4	1.6	-1.2	1.2	0.2	-0.5
Alzheimer’s Disease (including proxy)	0.4	0.6	2.4	0.7	0.9	-0.1	0.7	0.5	-0.5	0.7	1.6	0.6
Crohns Disease (2017)	1.2	2.6	5.8	-1.8	-0.1	-2.1	-1.0	2.1	-0.2	-1.1	-2.4	-1.9
Irritable Bowel Disease (IBD)	1.8	4.4	12.1	-1.6	0.9	-2.3	-0.8	1.7	-0.2	-3.0	-3.5	-2.4
Ulcerative Colitis (UC)	1.2	2.2	7.8	-0.6	1.3	-1.0	-0.4	0.5	-0.0	-2.8	-2.7	-1.2
Major Depression (MDD)	2.9	3.5	12.2	-1.9	0.5	-1.5	-1.0	-2.1	-1.7	-3.5	0.1	-2.2
Reaction Time	1.0	1.9	7.9	0.5	-1.0	0.2	0.0	1.8	2.8	-1.1	-1.7	0.4
Verbal and Numeric Reasoning (VNR)	3.2	7.8	27.0	-3.5	-5.2	-3.6	-1.3	0.5	-0.4	-1.4	-2.2	-3.0
Breast Cancer	1.0	2.4	6.9	2.3	0.2	1.9	0.9	0.4	2.6	0.9	-0.9	1.7
Ovarian Cancer	1.0	1.3	2.7	1.6	1.4	1.0	1.2	-1.5	1.6	-0.6	0.1	0.0
Prostate Cancer	2.2	3.1	7.4	-2.1	-2.7	-2.4	1.1	2.2	-0.5	-0.9	-0.9	-1.6
Age at First Birth	0.6	0.8	3.4	-0.6	-0.7	0.1	-1.3	0.5	-0.4	1.8	-0.7	-0.5
Bipolar Disorder (2011)	1.0	0.9	4.1	0.5	2.0	1.2	0.3	-1.3	-0.4	0.0	0.6	0.5
Body Mass Index (BMI) (2010)	0.3	0.4	1.7	0.5	0.3	0.9	-0.1	-1.3	0.5	0.5	0.4	0.4
Coronary Artery Disease (CAD)	1.0	1.2	3.8	0.1	1.7	0.8	-0.4	-1.0	-0.6	-1.9	1.1	-1.1
Crohns Disease (2012)	1.2	1.9	4.7	-1.8	0.5	-2.2	-0.0	1.4	-0.9	-0.7	-2.0	-1.5
Mean Putamen Volume	0.6	0.7	1.6	-0.8	0.7	-0.3	0.9	0.1	-1.1	0.2	1.0	-1.3
Fasting Glucose	0.9	1.1	5.3	0.7	1.1	1.1	0.7	-0.1	-0.2	2.3	0.4	1.1
HbA1C	1.0	1.1	5.0	1.6	1.1	-0.3	0.7	-0.5	-0.2	0.3	2.2	0.5
HDL Cholesterol	0.3	0.5	2.5	-0.7	-0.3	-1.6	-0.3	0.1	-0.8	0.0	-0.7	-0.5
LDL Cholesterol	0.9	1.4	5.7	1.0	-0.6	1.5	-0.2	-2.4	1.6	-0.1	-0.4	0.9
Lupus	0.5	0.7	1.8	-0.8	-0.2	-0.6	0.1	-0.5	-1.0	-1.1	-1.3	-1.1
Neuroticism (2016)	1.3	1.9	6.8	-1.7	-1.3	-1.1	-0.0	-0.7	-0.7	-2.6	-0.3	-1.9
Primary Biliary Cirrhosis	0.6	0.9	2.6	-0.2	-1.1	0.5	-0.1	0.7	1.2	-1.6	-1.4	0.3
Rheumatoid Arthritis	0.4	0.5	1.5	-0.7	-0.1	-0.7	0.4	-0.6	-1.2	0.6	-1.2	0.1
Schizophrenia (2014)	1.4	3.2	7.4	2.1	2.0	2.7	-0.2	-1.7	1.8	0.9	1.3	2.0
Triglycerides	2.1	3.4	10.2	1.6	0.2	2.7	0.5	-3.2	2.4	1.0	-0.6	1.7
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.7	0.9	0.0	0.9	-1.9	-0.2	0.1	-0.6	1.3	0.5
Ulcerative Colitis	2.4	3.4	15.1	-0.7	1.3	-1.6	-1.1	-0.3	-0.1	-3.9	-2.6	-1.6
Blood Eosinophil Count	0.4	2.7	6.3	1.6	1.0	2.5	0.8	-1.3	2.2	1.9	0.5	1.8
Blood Platelet Count	2.4	27.4	77.7	7.7	1.7	5.2	-1.0	0.6	8.8	4.5	-1.2	7.6
Blood Red Count	0.6	5.6	18.2	2.8	0.9	2.8	-1.8	1.1	4.3	1.1	0.1	3.2
Blood White Count	0.7	4.9	14.3	2.7	1.1	2.2	0.2	1.6	3.8	1.4	-1.6	3.1
Heel T-Score	0.1	0.7	1.5	-0.9	-1.1	-0.8	-1.2	-0.1	-1.2	-0.4	0.1	0.2
BMI	3.3	19.4	39.2	5.6	3.5	6.3	-0.9	-4.7	4.4	3.9	1.7	5.5
Height	0.3	5.9	28.7	-0.2	2.5	1.2	0.5	-2.4	-5.4	1.9	2.4	1.0
Waist Hip Ratio (WHR)	0.2	1.1	3.5	-0.4	-1.9	-0.8	-1.5	-0.1	1.3	1.2	0.4	-0.7
Systolic Blood Pressure	0.6	3.0	8.5	-1.1	2.0	-1.1	0.7	-2.4	-1.2	-1.6	1.3	-2.9
Smoking Status	2.5	5.9	12.2	-3.3	-0.5	-2.6	3.5	0.9	-2.6	-1.6	-2.7	-2.2
Allergy or Eczema	3.9	10.2	17.8	-4.1	-2.6	-4.2	-0.9	3.2	-4.0	-2.9	0.1	-3.9
Cardiovascular Disease	0.1	0.3	0.8	-0.1	-0.7	-0.5	-0.1	-0.3	0.5	-0.4	0.9	-0.8
Hypothyroidism (self reported)	0.9	2.1	4.4	1.9	0.2	1.6	-0.6	0.4	2.0	2.1	0.8	1.8
Respiratory disease	4.5	10.0	21.1	-4.6	-2.0	-4.1	-0.4	3.0	-3.2	-3.1	-0.0	-4.2
Type 2 Diabetes (T2D) (2018)	1.6	2.9	7.6	2.4	0.8	2.0	0.7	-0.6	2.2	1.6	-0.6	2.8
Lung FEV1/FVC ratio	1.2	6.2	17.5	-2.8	0.7	-2.3	-0.9	-1.3	-3.3	-3.2	-0.7	-4.2
Lung FVC	0.1	0.5	1.1	0.2	-0.5	0.5	-0.6	0.8	0.8	-0.5	-1.0	0.8
Neuroticism	0.4	0.9	3.3	-1.3	0.0	0.2	-0.9	-0.8	-0.4	-1.8	0.3	-1.3
Chronotype (morning person)	1.9	4.5	8.7	2.9	1.9	2.8	-2.0	0.5	2.9	0.1	1.4	2.3
Hair Pigment	0.1	2.5	4.5	1.6	0.9	2.1	0.7	-0.7	1.6	1.8	2.1	1.8
Tanning	0.1	1.0	3.5	-0.5	0.8	0.3	1.0	1.6	-0.4	1.9	-0.8	0.4
Hand grip strength (left)	0.1	0.4	0.9	-0.7	0.5	-0.1	-0.8	-0.6	-1.0	-0.4	0.5	-0.5
Number of treatments/medications taken	0.2	0.3	0.9	0.2	-0.1	0.2	0.6	0.6	0.6	0.7	0.9	-0.2
Average weekly spirits intake	0.8	1.0	2.7	-0.5	1.3	-0.2	0.4	-1.6	-1.0	0.5	1.2	-1.0
Sensitivity / hurt feelings	1.2	2.0	4.5	-1.5	-0.0	-0.6	-0.4	-0.6	-2.1	-1.6	2.1	-1.9
Frequency of depressed mood in last 2 weeks	1.3	1.9	6.0	-1.1	0.4	-1.1	-2.5	0.4	-1.9	-1.2	1.0	-1.3
Hearing difficulty/problems: Yes	1.1	1.6	5.1	2.3	1.6	1.1	-1.2	-1.4	0.7	-0.2	0.5	1.2
Relative age of first facial hair	5.6	11.5	26.6	-4.0	-0.6	-4.6	-1.0	0.5	-4.7	-3.8	1.2	-5.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.2	0.0	-0.2	-0.0	-0.0	0.3	-0.4	0.2	1.1	0.2
Ever used hormone-replacement therapy (HRT)	1.8	2.3	5.5	1.4	0.8	2.1	0.2	0.4	1.5	2.2	-1.1	2.3
Ever had hysterectomy (womb removed)	0.8	0.8	2.4	0.2	0.2	0.9	1.0	-1.3	-0.6	1.0	1.6	-0.2
Systolic blood pressure, automated reading	1.3	3.9	19.7	1.3	2.9	1.3	0.9	-4.4	0.5	0.1	1.4	-0.5
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	2.9	0.6	1.3	1.3	-0.3	-1.7	1.0	0.2	0.1	0.7
Angina	0.9	1.1	6.2	0.7	-0.1	0.7	0.8	2.5	0.2	0.8	-0.3	1.2
Medication for hormone replacement therapy	0.8	0.9	2.2	0.8	0.7	1.5	-0.8	0.2	0.4	1.4	-1.0	1.1
Vitamin and mineral supplements	0.5	0.7	2.5	0.6	0.3	0.6	-0.8	-0.1	1.6	1.3	-0.1	0.8
Supplements: Zinc	1.6	1.7	7.7	0.8	1.0	0.1	-0.2	0.9	-2.0	0.8	2.8	0.6
Medication: Co-codamol	0.6	0.7	3.0	-0.7	-0.5	-0.3	-0.3	-0.8	0.5	-0.8	-1.7	-0.5
Medication: Metformin	0.6	0.8	2.3	0.9	0.8	1.3	0.8	-0.1	1.2	-0.1	0.0	1.5
Diabetes (father)	0.4	0.5	1.4	-0.3	0.9	-0.9	0.1	0.8	-1.2	0.2	0.5	-0.4
Diabetes (mother)	1.5	1.9	5.1	-1.7	-1.6	-1.5	-0.6	-1.1	0.2	-0.4	-2.3	-1.8
Severe depression (siblings)	1.2	1.3	3.3	-1.0	0.1	-0.4	1.2	-1.8	-1.4	-1.3	0.5	-1.5
Pack years adult smoking proportion	3.5	5.3	15.5	-3.5	-3.9	-2.9	-0.5	0.8	-0.3	-0.6	-2.1	-2.3
Impedance of leg (right)	0.8	4.1	9.3	-2.8	-1.6	-3.0	0.1	1.7	-1.8	-1.9	-0.2	-2.6
Leg fat-free mass (left)	1.3	6.7	14.1	2.7	1.9	3.7	-0.6	-3.6	0.3	3.2	1.1	3.2
Trunk fat percentage	2.7	10.9	20.3	3.8	2.0	4.5	-1.2	-3.8	2.6	4.0	0.8	4.5
Hand grip strength (right)	0.1	0.4	1.4	-0.1	1.1	0.0	-0.6	-1.2	-0.7	0.1	0.1	0.0
Townsend deprivation index at recruitment	1.5	2.1	8.2	-1.9	-1.2	-1.5	-0.6	0.9	-1.2	-0.6	-2.9	-0.9
Current tobacco smoking	1.9	3.0	8.4	-2.9	-0.6	-1.8	2.2	0.5	-0.8	-0.6	-2.5	-1.8
Average weekly fortified wine intake	0.6	0.7	1.8	-0.5	1.0	-1.0	0.3	-0.8	-1.3	1.0	0.4	-0.7
Maternal smoking around birth	0.5	0.7	3.1	-0.6	0.5	-0.1	0.2	0.1	-1.4	1.8	-0.2	-0.5
Fed-up feelings	0.5	1.0	3.3	0.4	1.2	0.3	-1.8	-1.1	-1.1	0.6	0.8	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.7	-0.8	-0.5	0.0	-1.6	-0.6	-1.0	-0.2	-0.7	-0.4
Relative age voice broke	5.8	8.9	19.0	-3.9	-2.0	-4.3	-0.8	1.9	-2.7	-3.2	-1.0	-4.4
Taking other prescription medications	0.2	0.2	0.6	-0.8	-0.5	-0.8	0.1	0.1	-0.2	-0.5	-0.2	-0.6
Age when periods started (menarche)	9.0	21.6	45.2	-6.3	-1.6	-6.0	0.5	0.3	-5.6	-5.9	-2.1	-6.7
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.1	-1.1	-0.0	-0.9	0.2	-0.5	-1.0	0.1	0.7	-1.8
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	2.7	-1.0	-1.6	-1.4	-1.0	0.5	-0.5	-1.3	-0.0	-0.3
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.9	-0.6	1.4	-0.6	0.2	-0.6	-0.9	-0.2	0.9	-1.4
Qualifications: CSEs or equivalent	1.4	1.8	6.8	1.4	-0.7	1.5	0.2	0.1	2.6	-0.2	-1.0	1.9
Serious illness, injury or assault to yourself	1.1	1.3	3.8	-1.5	0.0	-1.5	1.9	0.5	-1.3	-0.2	-0.1	-1.2
High blood pressure	0.2	0.5	1.7	0.8	0.6	-0.3	0.6	-0.9	0.5	0.1	1.3	-0.5
Hayfever, allergic rhinitis or eczema	3.4	7.5	13.6	-3.5	-2.2	-3.1	-1.4	2.8	-3.7	-2.5	0.3	-3.2
Multivitamins +/- minerals	0.9	1.1	3.4	-1.1	-0.2	-1.1	0.7	-0.9	-1.8	-1.2	-0.3	-1.2
Stomach or abdominal pain in last month	1.4	1.7	5.4	-1.2	1.3	-1.3	-0.8	-1.0	-2.3	-0.8	0.5	-1.7
Supplements: Glucosamine	4.3	5.6	17.8	3.2	0.8	3.3	-0.2	0.3	2.1	2.2	1.1	4.2
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.5	-0.4	-0.6	0.4	-0.5	-0.7	0.4	-0.0	0.1	-0.2
Medication: Atenolol	1.0	1.2	2.9	1.6	0.6	1.3	0.5	-1.1	1.7	0.5	0.8	1.1
Medication: Levothyroxine sodium	1.5	2.5	4.9	1.8	0.8	2.0	-1.2	0.7	2.0	2.2	0.7	1.7
Sitting height	0.5	3.3	6.1	1.6	2.1	2.1	0.2	-2.2	-0.9	2.1	1.5	2.5
Chronic bronchitis/emphysema (father)	1.1	1.2	2.8	-1.1	-0.7	-1.5	-1.7	-0.5	-1.2	-0.3	-1.4	-0.8
High blood pressure (mother)	0.9	1.3	2.9	-0.9	1.0	-1.0	-0.8	-0.8	-1.1	-1.5	1.2	-1.7
Body mass index (BMI)	3.1	13.1	26.9	4.4	1.8	5.2	-0.5	-3.6	3.9	3.8	0.5	5.0
Impedance of leg (left)	0.9	4.5	10.3	-3.0	-2.0	-3.2	-0.8	2.3	-1.6	-1.5	-0.9	-2.5
Leg predicted mass (left)	1.3	7.0	14.5	2.8	2.0	3.8	-0.6	-3.7	0.3	3.3	1.1	3.3
Trunk fat mass	2.6	11.1	21.5	3.7	2.2	4.6	-1.0	-4.2	2.1	3.9	1.1	4.5
Waist circumference	2.5	9.0	17.1	3.5	1.1	4.1	-0.8	-3.6	2.9	3.8	1.0	3.7
Number of incorrect matches in round	2.2	3.6	8.2	2.7	0.6	2.1	0.1	1.0	1.4	2.7	1.3	2.9
Past tobacco smoking	3.7	6.7	14.4	3.3	0.1	3.1	-2.9	-1.1	3.8	2.1	1.4	3.1
Alcohol usually taken with meals	0.3	0.5	1.1	-0.1	-0.8	-0.4	-1.1	0.7	0.8	-0.8	-0.6	-0.9
Nervous feelings	0.4	0.8	1.9	0.2	1.1	1.4	-1.4	-1.0	0.2	-0.8	0.6	0.3
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	5.5	-2.0	-0.6	-2.0	-2.2	2.0	-2.3	-1.8	0.8	-1.9
Hearing difficulty/problems with background noise	2.9	4.6	10.9	2.9	3.3	2.7	-0.8	-1.7	1.1	1.1	2.3	2.0
Hair/balding pattern: Pattern 2	0.8	1.0	2.1	1.2	0.2	0.7	0.8	0.5	1.4	-0.1	-1.5	1.4
Had menopause	1.7	2.1	4.7	1.9	1.6	2.2	-0.5	-0.9	0.1	1.3	1.7	1.5
Had other major operations	0.5	0.6	2.1	-0.8	-1.5	-0.7	0.4	0.1	0.0	0.0	-0.1	-1.2
Forced vital capacity (FVC)	0.3	1.3	5.3	-1.6	-0.4	-1.1	-1.1	0.5	-2.3	-0.1	-0.4	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.6	3.6	-1.6	-1.9	-1.6	-1.0	0.3	-0.7	-1.5	-0.9	-1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	3.4	0.5	0.7	-0.4	-0.2	-0.5	-1.0	-1.8	0.4	-0.3
Qualifications: None of the above	1.1	2.3	5.1	0.9	1.3	2.0	0.3	-2.0	1.7	1.5	-0.6	2.3
Financial difficulties in last 2 years	1.4	1.9	3.6	-1.6	-0.8	-1.9	-1.7	1.7	-1.4	-0.6	-0.5	-1.6
Mouth/teeth dental problems	2.0	3.1	6.5	2.3	1.9	2.5	-1.1	-2.1	1.4	1.1	0.4	1.8
Heart attack	0.2	0.2	1.0	-0.5	0.1	0.7	0.2	-1.0	-0.2	-0.3	-0.4	-0.1
Allergy	5.1	11.8	21.7	4.7	2.6	4.2	0.6	-3.5	4.3	3.3	-0.1	4.3
Pain all over the body in last month	1.1	1.2	5.8	0.2	1.2	0.1	-0.1	-2.4	-0.5	0.4	1.5	-0.5
Diabetes (self-reported)	0.5	0.8	2.0	0.7	0.3	0.9	0.4	0.8	1.4	-0.2	-1.1	1.4
Hayfever/allergic rhinitis (self-reported)	2.4	3.1	5.9	-2.4	-1.9	-2.4	0.6	1.0	-2.2	-1.0	-0.4	-2.3
Medication: Ramipril	0.4	0.5	3.4	0.5	0.3	-0.2	-0.6	-0.3	-0.4	0.0	1.8	0.2
Medication: Simvastatin	1.7	2.5	4.7	2.2	1.7	2.1	0.7	0.1	1.1	1.6	1.1	2.2
Fluid intelligence score	2.1	4.4	11.2	-2.6	-3.3	-3.3	-0.2	1.1	-0.0	-1.1	-1.4	-2.5
Illnesses of siblings	0.9	1.2	3.5	1.5	-0.3	0.5	-0.9	1.9	-0.2	1.1	0.9	1.4
Neuroticism score	0.4	0.9	1.7	-0.8	0.6	0.5	-1.1	-1.3	-0.8	-1.2	0.7	-1.0
Weight	2.0	9.6	19.3	3.3	2.1	4.4	-0.5	-4.3	1.4	3.7	1.2	4.0
Impedance of arm (right)	1.5	6.9	15.5	-3.7	-1.4	-3.7	-0.0	0.7	-3.5	-2.2	-0.6	-3.9
Arm fat percentage (right)	2.4	9.4	19.3	3.6	1.5	4.4	-0.6	-3.5	3.1	3.3	0.4	4.2
Trunk fat-free mass	0.5	3.1	8.5	1.5	1.5	2.4	0.4	-2.9	-0.6	1.6	1.8	1.7
Hip circumference	3.2	13.8	30.8	4.5	2.7	5.6	0.1	-4.6	2.7	3.5	1.2	4.9
Time employed in main current job	0.9	1.1	5.9	0.8	-0.7	0.5	-2.4	-0.7	1.3	0.0	-0.2	0.4
Alcohol intake versus 10 years previously	1.9	2.8	6.4	2.5	1.7	2.2	0.1	-1.7	1.2	1.1	0.1	2.2
Father’s age at death	0.4	0.5	2.1	1.0	-0.4	0.5	-0.3	0.1	0.8	0.4	-0.2	1.5
Worrier / anxious feelings	0.4	0.7	2.6	-1.6	-0.6	-0.1	-1.1	-0.2	-0.3	-0.9	-0.1	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.5	-0.0	0.9	0.1	-1.6	-0.4	0.8	-0.1	0.1	-0.6
Falls in the last year	0.9	1.2	3.7	-1.9	-1.4	-1.5	-0.5	0.8	-0.4	-0.1	-0.3	-1.4
Hair/balding pattern: Pattern 3	2.7	4.0	7.7	2.6	1.5	2.2	-0.6	-0.4	1.6	2.0	2.7	2.8
Number of live births	0.7	1.0	5.2	-0.6	-2.3	-0.5	0.3	1.2	0.7	0.6	-0.8	0.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.5	8.9	-2.2	-0.2	-1.6	-1.2	-0.1	-3.0	-0.8	-0.7	-2.0
Pulse rate	2.3	3.8	9.4	-2.5	-0.2	-2.4	1.3	0.4	-2.7	-1.9	0.3	-3.1
Happiness	0.3	0.4	1.3	0.3	0.5	1.1	-0.5	-0.9	-0.1	-0.6	-0.3	0.4
Noisy workplace	1.9	2.3	9.4	-1.3	-1.4	-0.6	-0.2	-1.7	-0.3	-1.8	-3.1	-1.2
Qualifications: A levels/AS levels or equivalent	2.5	5.5	10.7	-2.3	-2.8	-3.3	-1.8	2.0	-1.9	-1.9	0.8	-3.1
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	2.8	-1.7	-1.5	-1.2	-1.2	1.0	-1.6	0.2	0.4	-0.8
Mouth/teeth dental problems: Dentures	1.1	1.9	5.0	-2.2	-0.7	-1.9	0.6	1.0	-1.4	-0.3	-1.1	-1.9
Asthma	1.5	3.0	5.4	-2.3	-1.0	-1.6	-0.4	2.0	-2.2	-2.1	0.5	-2.1
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	3.0	-1.2	-0.8	-1.3	1.7	1.1	-0.1	-0.9	-1.4	-1.1
Medication: Cholesterol lowering	2.4	3.7	9.0	3.0	1.6	2.7	0.5	-0.1	1.8	1.4	1.1	2.8
Depression (self-reported)	1.6	1.9	5.0	-1.1	-1.3	-1.5	-1.4	-0.7	-1.0	-2.2	0.6	-1.8
Medication: Lansoprazole	1.4	1.6	3.5	-1.9	-0.7	-0.8	-0.5	-0.2	-1.7	-1.0	-1.7	-1.8
Prospective memory result	0.4	0.5	1.1	0.3	0.4	0.1	0.9	-0.5	-1.0	0.7	0.5	1.0
Lung cancer (father)	0.6	0.7	2.4	-0.2	-0.1	-0.1	-1.5	-0.7	1.1	0.6	-1.2	-0.0
Illnesses of mother	1.1	1.3	4.3	-0.1	-1.5	-0.7	0.1	2.1	1.1	0.2	-1.9	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	7.6	-2.6	-1.0	-1.8	-0.8	0.9	-2.8	-1.1	-1.5	-1.9
Pulse wave Arterial Stiffness index	0.7	0.8	3.5	-0.6	-0.2	-0.3	0.0	1.4	-1.9	0.2	1.3	-0.0
Impedance of arm (left)	0.9	4.1	9.1	-2.7	-0.9	-3.0	-0.0	1.1	-2.5	-1.7	-0.7	-3.0
Arm fat mass (right)	2.8	11.6	23.9	3.9	1.8	4.9	-0.5	-4.1	3.0	3.8	0.6	4.6
Trunk predicted mass	0.6	3.2	8.9	1.5	1.5	2.5	0.4	-3.0	-0.5	1.6	1.7	1.8
Standing height	0.4	4.5	25.0	-1.8	1.1	-1.0	-0.3	-2.0	-5.0	0.5	1.8	-1.5
Length of working week for main job	2.0	2.2	4.4	-1.9	-0.9	-2.1	1.5	0.6	-1.8	-0.2	-1.2	-1.9
Exposure to tobacco smoke at home	0.6	0.7	1.8	0.6	1.4	0.8	-1.1	0.3	0.2	0.4	0.3	1.2
Breastfed as a baby	0.4	0.5	2.4	0.1	-0.6	-0.7	-1.5	0.9	-0.5	-0.3	-0.3	0.5
Tense / ‘highly strung’	0.2	0.4	0.8	-0.9	-0.8	-0.1	-0.7	0.7	-0.4	-0.3	0.4	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.1	-0.8	-0.6	0.1	-0.8	-1.1	-0.5	-1.4	0.7	-0.9
Hair/balding pattern: Pattern 4	0.7	1.7	3.3	-1.8	-1.6	-1.1	-0.7	1.0	1.2	-0.8	-1.2	-1.8
Birth weight of first child	0.4	0.7	1.3	-0.9	-0.6	-1.1	0.4	1.1	-1.0	-0.7	0.5	-0.6
Peak expiratory flow (PEF)	1.6	3.7	8.4	-2.6	-0.2	-1.5	-2.9	-1.5	-2.9	-0.3	-0.5	-2.3
Pulse wave reflection index	0.5	0.6	1.7	0.5	-0.1	0.8	-1.2	-0.3	0.0	0.7	0.9	1.3
Ever highly irritable/argumentative for 2 days	1.3	1.6	5.3	-0.7	0.2	-1.5	-0.6	0.7	-2.0	-2.3	1.0	-0.8
Loud music exposure frequency	0.9	1.0	2.8	0.1	0.3	0.7	0.8	-0.3	1.6	-1.5	-1.7	0.4
Qualifications: O levels/GCSEs or equivalent	5.5	8.8	21.0	-3.2	-3.6	-4.6	0.3	2.3	-3.1	-2.1	1.0	-3.9
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	5.1	-1.4	-2.3	-1.5	0.2	1.3	-0.2	-0.3	-0.8	-0.4
Blood clot in the leg (DVT)	0.5	0.6	1.4	-1.2	-0.7	-0.9	0.2	0.9	0.0	0.2	-1.1	-0.9
Medication: Paracetamol	1.4	2.3	4.6	-1.8	-1.6	-2.0	-1.4	2.1	0.2	-0.6	-1.6	-1.2
Headache pain in last month	2.1	3.6	8.5	-2.9	-1.8	-2.6	-1.5	0.6	-1.2	-1.5	-0.3	-2.8
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	4.5	-2.1	-0.6	-1.8	0.1	0.5	-1.7	-0.8	-1.0	-1.9
Glaucoma (self-reported)	1.5	1.8	9.0	-0.1	3.0	0.2	-0.1	-1.0	-1.0	-0.4	1.9	-0.9
Gout (self-reported)	0.6	0.8	2.2	1.0	-0.7	0.6	0.2	0.3	1.5	0.2	-1.4	1.1
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	7.2	2.0	1.1	1.9	-0.1	-0.1	1.8	2.7	0.9	1.9
Medication: Amlodipine	0.4	0.5	1.9	0.5	-0.3	0.8	1.4	-0.3	0.8	0.9	-0.4	0.5
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.2	-0.1	1.1	0.4	-0.8	0.6	-0.8	0.1	0.1	0.0
Birth weight	1.1	2.3	5.3	-2.3	-2.3	-1.9	-0.8	0.2	-1.9	-0.5	0.5	-1.3
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.9	-1.7	-1.4	-0.3	0.5	0.2	-1.2	-0.8	-0.2	-1.5
High blood pressure (siblings)	0.9	1.3	2.5	-1.4	0.8	-1.3	0.7	-0.6	-1.5	-1.2	-0.0	-1.6
Forced vital capacity (FVC), Best measure	0.4	1.3	3.3	-1.7	-0.6	-1.0	-0.8	1.4	-1.8	-0.2	-1.3	-0.4
Body fat percentage	2.8	11.2	21.8	3.9	1.7	4.6	-1.0	-3.6	3.2	3.8	0.7	4.7
Leg fat percentage (right)	2.8	10.0	20.2	3.6	1.7	4.5	-0.3	-3.7	3.2	3.2	1.0	4.4
Arm fat-free mass (right)	1.2	6.3	14.1	2.8	2.0	3.8	-0.3	-3.2	0.8	2.7	1.5	3.4
Exposure to tobacco smoke outside home	0.5	0.6	1.3	-1.0	-1.1	-0.6	0.5	-0.5	0.9	-0.7	-0.9	-0.8
Comparative body size at age 10	0.5	1.4	5.7	-0.8	0.3	0.2	-1.5	-0.5	-1.7	2.4	0.8	-0.4
Number of full brothers	1.5	1.9	5.2	-2.3	-1.2	-1.9	-0.7	-0.0	-1.2	-0.5	-1.0	-1.8
Worry too long after embarrassment	0.4	0.7	3.0	-0.8	0.7	0.5	-0.4	-1.7	-0.6	-0.8	0.0	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	2.1	2.7	6.7	-1.5	0.1	-1.8	0.8	-0.9	-2.4	-0.9	2.0	-2.6
Wheeze or whistling in the chest in last year	2.1	3.7	11.3	-3.4	-1.7	-2.1	-0.1	0.7	-1.4	-1.7	-1.8	-2.6
Number of children fathered	2.6	2.9	7.4	-1.6	-2.4	-2.7	-0.9	1.2	-0.3	-1.6	-0.0	-2.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.1	1.1	1.4	1.3	0.8	-2.0	0.9	-0.2	1.1	0.9
Age at first live birth	0.2	0.4	2.0	0.3	-0.2	0.1	-0.9	0.4	1.4	0.3	-0.3	-0.1
Pulse wave peak to peak time	0.6	0.7	2.5	0.5	0.2	0.3	0.0	-1.4	1.6	-0.1	-1.2	-0.0
Health satisfaction	0.4	0.6	3.0	0.8	0.3	0.5	-1.7	0.5	-0.0	-0.0	0.8	0.5
Shortness of breath walking on level ground	0.4	0.5	2.0	-0.1	0.2	0.5	1.3	-1.4	-0.6	0.5	0.5	-0.3
Qualifications: College or University degree	0.4	1.3	5.5	-1.4	-0.9	-1.2	0.4	0.2	-0.6	-1.0	-0.6	-2.3
Eye problems/disorders: None of the above	0.8	1.0	2.3	-0.8	-1.4	-0.6	-1.2	1.5	-0.5	-0.1	-1.4	0.0
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.5	0.2	-0.0	-0.7	-0.0	1.2	-0.4	-0.0	0.4	-0.1
Emphysema/chronic bronchitis	1.9	2.2	5.4	-1.8	0.2	-1.8	2.3	1.5	-0.7	-1.2	-0.4	-1.7
Medication for pain relief, constipation, heartburn	0.7	1.2	2.9	0.7	0.9	1.1	-1.6	-1.7	-0.9	-0.1	1.3	0.5
Neck or shoulder pain in last month	0.4	0.6	2.5	0.3	-1.0	-0.7	0.3	1.6	-0.0	-0.8	-0.6	0.6
Medication: Blood pressure	0.3	0.5	1.8	0.8	-0.5	0.1	0.1	-0.5	1.4	0.4	1.1	0.3
Angina (self-reported)	0.9	1.2	7.1	0.8	0.2	0.5	0.8	2.7	0.1	1.0	-0.1	1.2
Migraine (self-reported)	1.1	1.4	4.4	-2.1	0.5	-1.6	-0.9	-0.2	-1.2	-0.4	-0.2	-1.7
Medication: Ibuprofen	2.0	2.4	7.6	-1.6	-1.1	-1.7	2.8	1.6	-0.6	-1.2	-1.5	-1.2
Medication: Allopurinol	2.2	2.9	11.1	1.9	-0.8	1.8	0.1	-0.0	3.3	0.1	-1.7	2.2
Medication: Omeprazole	2.8	3.3	5.8	2.2	2.4	1.9	2.4	-0.0	1.9	1.3	0.6	2.1
Medication: Seretide 50 evohaler	3.7	4.2	9.3	-3.0	-1.9	-2.4	-0.4	2.1	-1.0	-2.8	-0.9	-2.3
Mean time to correctly identify matches	1.5	2.9	14.2	1.8	-0.1	1.6	0.1	1.3	3.8	-0.4	-0.1	2.1
Heart disease (mother)	0.6	0.7	2.7	-0.9	0.6	-0.6	0.6	-1.2	-1.6	-0.3	-0.3	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.2	-1.4	-1.0	-1.5	-0.3	-0.2	-1.5	0.2	-0.1	-1.5
Whole body fat mass	2.9	12.0	23.9	3.9	1.8	4.9	-0.9	-4.1	2.8	3.9	0.7	4.9
Leg fat mass (right)	3.3	12.9	27.2	4.1	2.0	5.2	-0.8	-4.0	2.9	4.1	0.7	5.2
Arm predicted mass (right)	1.3	6.8	13.8	3.0	1.9	3.7	-0.5	-3.1	1.2	2.9	1.5	3.7
Pulse rate, automated reading	2.6	8.6	20.8	-4.0	-1.1	-3.8	1.7	-0.8	-3.7	-2.2	-1.3	-4.6
Alcohol intake frequency.	0.4	0.9	3.9	-0.3	-0.6	-0.4	-1.1	-2.0	1.2	-0.6	-1.0	-0.3
Comparative height size at age 10	1.3	7.0	12.7	2.5	2.4	3.5	-0.1	-3.4	-0.2	3.6	1.5	3.5
Number of full sisters	0.3	0.4	1.4	-0.3	0.6	-0.8	-0.6	1.2	-0.0	-0.3	0.3	-0.5
Suffer from ‘nerves’	0.4	0.7	3.8	-0.5	-0.9	-0.2	-0.7	0.6	-0.3	-1.9	-0.3	-0.3
Overall health rating	0.1	0.3	0.7	-0.8	0.0	-0.6	-0.9	0.6	-0.5	0.1	-0.4	-0.5
Chest pain or discomfort	4.6	6.6	12.5	-3.5	-1.4	-3.4	0.0	1.4	-3.2	-2.9	0.1	-3.5
Had major operations	1.3	1.5	4.0	-0.2	-1.5	1.2	-1.3	2.0	0.3	1.2	-1.2	1.1
Age at last live birth	0.9	1.3	4.7	-1.3	-1.7	-1.1	-2.2	0.6	0.5	-0.5	-0.4	-0.7
Family relationship satisfaction	0.2	0.3	1.1	-0.1	-0.7	-0.6	-1.1	0.2	-0.7	-0.2	-0.4	-0.2
Leg pain on walking	0.7	0.8	2.7	0.3	-1.6	0.1	0.5	0.8	-1.4	0.7	-0.4	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.3	0.2	-0.6	-1.8	-1.0	1.4	-0.5	-0.9	-0.8	-0.7
Commuting to job workplace: Car/motor vehicle	0.8	0.9	3.1	1.3	-0.4	0.7	-0.4	0.1	0.8	1.1	-0.9	1.8
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.9	0.2	-0.4	0.3	1.4	-1.4	0.5	-0.0	0.1	-0.2
Medication: Aspirin	0.3	0.5	0.9	0.1	-0.9	-0.7	0.4	0.7	0.8	-0.7	0.9	-0.4
Supplements: Vitamin C	0.3	0.4	1.1	-0.1	0.1	-0.2	0.8	0.4	-1.0	-1.1	0.4	-0.4
Knee pain experienced in last month	1.3	2.1	5.0	2.0	1.0	1.1	-0.3	0.7	0.4	2.2	1.8	1.9
Hypertension (Self-reported)	0.3	0.7	2.2	1.1	0.5	0.1	0.5	-1.1	0.8	0.7	1.5	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.7	-0.1	1.9	-0.2	0.5	-0.9	-1.3	0.1	0.6	-1.1
Illnesses of father: Heart disease	1.1	1.5	4.4	-2.1	0.4	-1.2	0.2	0.2	-1.3	-0.7	-1.3	-1.9
Illnesses of siblings: Diabetes	0.4	0.5	1.4	0.1	1.1	0.1	-0.8	-0.8	0.5	-1.2	0.5	-0.0
Smoking status: Previous	2.9	4.4	9.1	-2.4	-0.6	-2.7	1.3	1.1	-3.0	-2.1	-1.3	-2.8
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	6.7	-2.2	-1.8	-1.7	0.6	0.4	-2.6	-0.6	-0.2	-1.6
Whole body fat-free mass	0.8	4.8	10.9	2.1	1.7	3.2	-0.2	-3.3	-0.1	2.5	1.5	2.6
Leg fat-free mass (right)	1.1	5.7	11.4	2.4	1.7	3.4	-0.9	-3.2	0.0	3.3	0.7	3.0
Arm fat percentage (left)	2.7	10.6	21.2	4.0	1.7	4.6	-0.5	-3.2	3.3	3.6	0.4	4.6
Average weekly red wine intake	0.8	1.2	3.4	-1.9	-1.5	-1.1	0.2	0.7	-0.8	0.6	-0.0	-1.8
Handedness (chirality/laterality): Left-handed	2.4	2.9	8.2	-2.0	-0.1	-2.9	-1.2	1.9	-1.4	-1.0	-0.8	-2.1
Mood swings	1.5	2.6	6.0	-2.1	-0.1	-1.3	-1.8	-1.3	-2.0	-1.6	0.1	-2.5
Loneliness, isolation	2.3	3.2	7.2	1.9	0.7	2.7	-2.3	0.7	1.2	1.7	0.1	2.6
Long-standing illness, disability or infirmity	0.1	0.2	0.5	0.5	0.7	0.1	0.3	-0.4	0.0	0.7	0.5	0.4
Ever had bowel cancer screening	0.3	0.3	1.5	-0.3	-0.7	0.0	-1.2	0.7	0.3	-0.0	0.1	-0.3
Diabetes diagnosed by doctor	0.5	0.8	1.9	0.9	1.1	1.0	0.3	0.8	1.2	0.2	-0.6	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	3.5	0.6	-0.8	-0.4	0.0	1.9	0.8	-0.5	0.0	1.2
Friendships satisfaction	0.7	0.8	1.6	0.9	1.0	1.2	-1.2	-1.2	-0.3	0.2	0.5	0.8
Qualifications: nursing, teaching	1.9	2.9	7.6	-1.5	-2.3	-1.6	-1.4	0.4	0.0	-2.8	-1.2	-2.2
Commuting to job workplace: Walk	1.6	1.8	4.0	-0.7	-0.8	-2.0	-1.7	0.4	-1.6	-1.8	0.7	-1.2
Eye problems/disorders: Cataract	2.6	3.0	6.6	2.6	2.3	1.6	1.4	-1.2	0.6	1.3	2.2	1.6
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.9	-0.7	-1.4	-0.4	0.8	1.0	0.6	0.0	-0.1	-0.3
Medication for cholesterol	1.8	2.7	5.1	-2.1	-2.0	-2.3	0.1	0.9	-1.9	-1.6	-0.6	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.3	-0.4	-0.9	-0.0	1.2	0.3	1.2	-0.0	-1.8	-0.2
Back pain experienced in last month	0.7	1.1	4.4	1.4	0.8	0.6	-0.3	-0.5	2.1	0.8	-0.2	1.1
Mineral and other dietary supplements	0.4	0.5	1.2	-0.7	-0.5	-0.4	-0.8	-0.3	0.7	-1.1	-0.3	-1.0
Breast cancer (self-reported)	0.3	0.4	1.3	0.3	1.0	-0.2	0.9	0.5	0.1	1.1	0.4	-0.3
Asthma (self-reported)	1.3	2.5	4.5	-2.0	-0.8	-1.4	-0.4	1.9	-2.1	-1.8	0.9	-1.8
Osteoporosis (self-reported)	2.2	2.8	6.6	-2.5	-2.0	-2.0	0.1	0.4	-1.7	-0.9	-0.7	-2.6
Osteoarthritis (self-reported)	5.3	6.9	17.0	3.6	2.5	3.7	1.0	-1.1	2.0	2.2	0.9	4.1
Medication: Aspirin	0.3	0.4	1.3	0.6	-0.3	-0.3	0.4	0.3	1.0	-0.4	1.1	-0.0
Medication: Gliclazide	0.5	0.6	1.4	1.1	0.8	0.8	-0.7	0.6	-0.1	0.3	0.7	1.2
Illnesses of father: None of the above (group 1)	1.6	2.0	6.6	1.6	-0.9	1.7	-1.0	-0.7	2.6	0.1	-0.7	1.7
Smoking status: Current	1.3	2.1	6.7	-2.2	-0.1	-1.1	2.6	0.4	-0.5	-0.3	-2.0	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	7.1	0.0	1.2	-0.8	-2.7	0.9	-1.8	0.4	0.6	-0.1
Whole body water mass	0.8	4.8	11.0	2.1	1.8	3.2	-0.1	-3.3	-0.1	2.4	1.5	2.6
Leg predicted mass (right)	1.1	5.6	11.3	2.4	1.6	3.4	-0.9	-3.2	0.1	3.2	0.7	3.0
Arm fat mass (left)	2.9	11.8	23.8	4.0	1.8	4.9	-0.3	-3.9	3.1	3.9	0.6	4.8
Number of self-reported non-cancer illnesses	0.5	0.9	5.1	0.1	0.3	-0.5	-0.8	0.7	-1.1	0.1	2.3	-0.6
Average weekly champagne plus white wine intake	0.3	0.4	2.4	0.2	0.3	0.5	-0.6	0.1	0.4	0.2	1.5	0.1
Miserableness	0.5	0.9	3.5	-0.9	-1.1	-0.8	-1.9	0.4	-0.2	-1.2	-0.2	-0.8
Guilty feelings	0.8	1.2	3.1	-1.3	-0.5	-0.7	0.7	-0.3	-1.8	-1.2	0.4	-1.7
Wears glasses or contact lenses	0.4	0.4	1.8	-0.2	-0.0	-1.3	0.7	-0.1	-0.7	0.1	0.6	-0.9
Ever taken oral contraceptive pill	0.5	0.6	1.6	-1.0	-0.8	-0.5	-0.2	0.7	-0.4	0.3	-1.3	-0.9
Hearing aid user	0.8	0.9	2.6	-0.5	0.4	-1.5	0.6	0.2	-1.5	-0.6	0.4	-1.6
Mother’s age at death	0.6	0.7	3.4	0.3	-0.9	0.7	-0.9	-0.0	1.8	-0.2	-0.7	0.5
Financial situation satisfaction	0.5	0.7	1.9	-1.0	-0.5	0.1	-1.4	0.7	-0.9	-0.0	-0.9	-0.8
Tinnitus: Yes, now most or all of the time	1.0	1.1	2.3	1.1	1.5	1.1	-0.6	-0.4	-1.4	0.2	1.5	0.7
Commuting to job workplace: Public transport	0.7	0.8	3.1	-0.8	0.3	-0.6	0.6	0.1	-0.7	-1.1	1.8	-1.2
Eye problems/disorders: Glaucoma	1.6	1.9	6.8	-1.0	2.6	-0.6	-0.1	-1.3	-1.6	-1.0	0.8	-1.8
Medication: Blood pressure	1.2	2.2	4.4	2.0	2.1	1.6	0.4	-1.6	1.4	1.0	1.5	1.2
Pain type(s) experienced in last month: Hip pain	1.1	1.4	3.4	1.5	0.5	1.9	-1.1	-0.0	1.5	0.2	-0.2	1.7
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.7	0.5	-0.1	0.5	0.8	-0.4	-0.0	0.8	-0.4	0.5
High cholesterol (Self-reported)	1.2	2.1	4.1	2.0	1.9	2.0	0.5	-1.0	1.0	0.9	0.6	2.0
Medication: Bendroflumethiazide	3.1	4.7	9.3	3.0	2.1	2.6	-0.4	-2.7	1.7	1.9	2.0	2.1
Medication: Paracetamol	1.1	1.8	3.2	-1.6	-1.3	-1.4	-1.1	1.8	0.9	-0.8	-1.6	-1.2
Medication: Lisinopril	1.4	1.8	8.0	1.5	-0.3	1.0	-0.0	-1.4	2.8	-1.0	-0.5	1.0
Medication: Atorvastatin	0.4	0.5	1.6	0.3	1.3	-0.3	-0.2	-0.8	-0.5	-0.3	1.1	0.4
Illnesses of father: High blood pressure	0.6	0.7	3.0	-0.5	0.2	-0.6	-0.1	0.1	-1.4	0.4	1.7	-0.8
Alcohol drinker status: Never	2.9	3.5	8.5	-2.9	-2.3	-2.5	0.8	1.1	-0.6	-0.7	-1.2	-2.7
Ever smoked	4.2	7.4	13.5	-3.7	-0.6	-3.6	2.1	1.9	-3.3	-2.5	-1.8	-3.3
Basal metabolic rate	1.1	6.2	13.4	2.5	1.9	3.6	-0.3	-3.7	0.2	3.0	1.4	3.0
Leg fat percentage (left)	2.7	9.8	19.6	3.5	1.5	4.3	-1.0	-3.3	3.3	3.5	0.7	4.4
Arm fat-free mass (left)	1.3	6.4	14.3	2.5	1.9	3.7	-0.3	-3.8	0.8	2.7	1.3	3.2
Number of operations (self-reported)	0.8	1.2	4.0	-0.9	-2.0	-0.2	0.0	1.3	-1.0	1.8	-0.4	-0.2
Average weekly beer plus cider intake	5.1	7.3	19.1	3.7	1.4	3.9	0.3	0.8	2.4	3.0	0.6	4.4
Irritability	2.5	4.3	12.0	-3.3	-0.8	-2.3	0.4	-1.0	-2.6	-1.4	0.3	-3.5
Risk taking	1.5	2.2	4.8	1.2	1.7	1.0	-0.7	1.3	-0.4	2.0	2.2	1.8
Ever had prostate specific antigen (PSA) test	1.9	2.2	4.4	-1.8	-0.9	-1.5	-1.1	1.2	-0.1	-2.1	-1.7	-1.8
Fractured/broken bones in last 5 years	1.1	1.5	3.6	-1.9	-1.4	-1.3	-0.3	0.7	-1.5	0.5	-1.1	-1.3
Age started oral contraceptive pill	0.4	0.5	0.9	-0.6	-0.5	-0.9	-0.9	-0.0	-0.6	-0.5	0.9	-0.8
Diastolic blood pressure, automated reading	1.1	3.4	18.9	-1.3	-0.8	-1.1	0.2	-4.3	-0.7	-0.8	-0.2	-2.6
Ever depressed for a whole week	0.3	0.3	1.9	-0.1	0.1	-0.2	-0.7	0.1	-0.3	-1.4	-0.5	-0.3
Unable to work because of sickness or disability	0.1	0.1	0.9	-0.2	-0.1	0.1	0.2	0.3	0.1	0.9	-0.5	-0.2
Commuting to job workplace: Cycle	1.3	1.6	3.3	-1.4	0.1	-1.8	0.1	1.7	-1.3	-1.1	0.6	-1.7
Myopia	0.2	0.4	1.3	0.1	0.2	0.1	-0.1	0.0	0.8	-1.1	1.1	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.3	-0.4	-0.2	0.4	-0.3	0.2	-0.4	0.2	-1.1	0.6
Cholesterol lowering medication	1.3	1.9	5.2	1.5	2.3	1.7	0.4	-1.2	0.8	1.0	1.2	1.5
Medication: Omeprazole (e.g. Zanprol)	2.2	2.7	7.3	1.7	2.5	1.4	2.7	-0.5	0.9	1.7	0.8	1.4
Pain experienced in last month	0.5	0.8	1.7	-0.9	-0.2	-0.9	0.9	0.2	-1.3	-1.1	-0.3	-1.3
Supplements: Calcium	0.7	0.8	3.8	-0.5	0.7	-0.9	-0.5	0.5	-1.9	0.5	0.2	-0.8
Basal cell carcinoma (self-reported)	1.1	1.3	6.8	0.3	1.6	0.8	0.0	-2.6	-0.2	0.7	-0.8	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.1	-0.5	0.2	0.8	0.2	-1.1	-0.3	-0.3	-0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	2.2	-1.5	-0.8	-1.1	-0.2	1.1	-0.3	0.4	-1.1	-1.0
Heart disease (siblings)	0.9	1.1	3.7	-1.6	-0.5	0.3	0.9	-0.7	0.3	-0.7	-1.9	-1.3
Alcohol drinker status: Previous	4.7	5.4	11.0	-3.3	-2.5	-3.1	-2.3	0.0	-1.4	-1.9	-1.5	-2.9
Pack years of smoking	2.6	3.9	11.9	-3.0	-3.5	-2.5	-0.3	0.7	-0.1	-0.4	-1.5	-2.0
Impedance of whole body	0.8	4.2	9.6	-2.9	-1.5	-3.1	-0.4	1.7	-2.0	-1.6	-0.7	-2.7
Leg fat mass (left)	3.1	12.0	24.9	3.9	1.8	5.0	-1.0	-3.8	3.0	4.1	0.5	4.9
Arm predicted mass (left)	1.3	6.5	14.0	2.5	1.8	3.7	-0.4	-3.7	1.0	2.8	1.5	3.3