Best TWAS P=2.41e-09 · Best GWAS P=2.99e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ARFRP1 | 0.07 | 0.07 | lasso | 3 | 0.06 | 5.3e-08 | -5.3 | 5.3 | 1.0e-07 | -0.95 | 0.01 | 0.99 | FALSE |
| 2 | YFS | Blood | LIME1 | 0.12 | 0.19 | enet | 15 | 0.19 | 5.3e-59 | -5.9 | -6.0 | 2.4e-09 | 0.99 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | TNFRSF6B | 0.02 | 0.01 | enet | 7 | 0.01 | 6.9e-03 | -4.3 | -5.2 | 2.0e-07 | 0.92 | 0.02 | 0.86 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TNFRSF6B | 0.05 | 0.02 | blup | 44 | 0.03 | 2.9e-03 | -5.5 | -5.2 | 1.6e-07 | 0.92 | 0.01 | 0.69 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ARFRP1 | 0.03 | 0.02 | lasso | 2 | 0.02 | 1.2e-03 | -5.3 | 5.4 | 8.5e-08 | -0.96 | 0.01 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LIME1 | 0.04 | 0.05 | blup | 47 | 0.05 | 9.0e-06 | -5.9 | -5.9 | 4.5e-09 | 0.97 | 0.00 | 0.99 | FALSE |