Best TWAS P=3.48e-12 · Best GWAS P=1.24e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 6.8 | -7.0 | 3.5e-12 | -0.99 | 0.0 | 1.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SLC35F6 | 0.05 | 0.04 | enet | 11 | 0.04 | 8.0e-06 | -4.7 | 5.2 | 2.5e-07 | 0.73 | 0.2 | 0.79 | FALSE |