[Hub]/) : Traits : Leg fat mass (right) : ← →

chr2:35,883,253-37,567,226

Best TWAS P=1.04e-09 · Best GWAS P=1.16e-09 conditioned to 6.81e-09

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FEZ2	0.16	0.24	lasso	2	0.22	1.3e-26	6.0	-6.0	1.5e-09	0.04	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	AC007401.1	0.10	0.02	lasso	4	0.02	5.4e-03	5.6	6.0	2.1e-09	-0.09	0.05	0.89	FALSE
3	GTEx	Artery Tibial	CRIM1	0.10	0.04	lasso	4	0.05	1.4e-04	5.6	-6.1	1.4e-09	0.05	0.04	0.95	FALSE
4	GTEx	Brain Cerebellar Hemisphere	CRIM1	0.36	0.21	lasso	5	0.16	5.4e-05	5.8	5.8	5.3e-09	0.00	0.04	0.88	FALSE
5	GTEx	Brain Cerebellar Hemisphere	FEZ2	0.41	0.30	lasso	6	0.28	8.6e-08	5.7	5.8	5.9e-09	0.00	0.03	0.96	FALSE
6	GTEx	Brain Cerebellar Hemisphere	AC007401.1	0.40	0.26	lasso	4	0.22	2.3e-06	5.8	5.8	6.2e-09	0.00	0.04	0.95	FALSE
7	GTEx	Brain Cerebellar Hemisphere	RP11-490M8.1	0.37	0.18	lasso	4	0.15	1.2e-04	5.9	6.0	2.3e-09	0.01	0.03	0.90	FALSE
8	GTEx	Brain Cerebellum	FEZ2	0.44	0.26	lasso	6	0.23	2.6e-07	5.5	5.8	7.9e-09	0.01	0.06	0.94	FALSE
9	GTEx	Brain Cerebellum	AC007401.1	0.27	0.21	enet	5	0.20	1.5e-06	5.8	5.8	6.8e-09	-0.01	0.05	0.93	FALSE
10	GTEx	Brain Cerebellum	RP11-490M8.1	0.21	0.21	lasso	4	0.20	1.4e-06	5.0	5.3	1.4e-07	0.01	0.06	0.91	FALSE
11	GTEx	Spleen	FEZ2	0.42	0.16	enet	25	0.17	3.9e-05	5.0	6.0	2.2e-09	0.01	0.05	0.86	FALSE
12	GTEx	Whole Blood	FEZ2	0.11	0.09	enet	25	0.10	8.4e-10	5.7	5.7	1.6e-08	-0.08	0.03	0.97	FALSE
13	GTEx	Whole Blood	AC007401.1	0.06	0.06	lasso	5	0.05	4.6e-05	5.7	6.0	1.5e-09	0.00	0.04	0.95	FALSE
14	NTR	Blood	CRIM1	0.09	0.10	lasso	6	0.11	3.1e-32	5.1	-5.5	3.1e-08	0.01	0.09	0.91	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	FEZ2	0.41	0.55	lasso	5	0.58	3.1e-93	6.0	-5.8	6.0e-09	0.01	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	FEZ2	0.01	0.01	blup	85	0.01	1.0e-03	5.8	-6.1	1.0e-09	0.05	0.02	0.96	TRUE
17	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FEZ2	0.06	0.05	lasso	4	0.04	3.3e-03	5.4	-5.5	4.6e-08	0.01	0.02	0.89	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FEZ2	0.11	0.03	blup	84	0.07	6.1e-05	6.0	-5.3	1.2e-07	0.02	0.02	0.96	FALSE
19	The Cancer Genome Atlas	Esophageal Carcinoma	FEZ2	0.11	0.01	blup	87	0.02	7.1e-02	5.5	-5.2	1.6e-07	-0.03	0.02	0.64	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FEZ2	0.04	0.00	blup	88	0.02	6.1e-03	5.5	-5.2	2.0e-07	0.01	0.02	0.83	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	FEZ2	0.06	0.05	blup	87	0.08	1.4e-08	6.0	-5.9	3.3e-09	0.03	0.02	0.98	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	FEZ2	0.07	0.06	blup	87	0.06	2.4e-06	5.9	-5.2	1.5e-07	0.01	0.02	0.98	FALSE