[Hub]/) : Traits : Leg fat mass (right) : ← →

chr3:182,655,858-184,238,310

Best TWAS P=7.68e-09 · Best GWAS P=9.98e-09 conditioned to 0.946

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KLHL24 0.42 0.60 bslmm 493 0.66 4.5e-107 -5.3 -5.2 1.9e-07 -0.20 0.06 0.94 FALSE
2 GTEx Adipose Subcutaneous KLHL24 0.15 0.10 lasso 6 0.10 1.4e-08 -5.2 5.7 9.7e-09 0.33 0.06 0.94 FALSE
3 GTEx Brain Caudate basal ganglia KLHL24 0.22 0.21 lasso 3 0.19 3.5e-06 -5.3 5.3 1.1e-07 0.25 0.06 0.90 FALSE
4 GTEx Brain Cerebellum KLHL24 0.52 0.14 enet 26 0.16 1.9e-05 -5.3 5.2 2.4e-07 0.31 0.06 0.92 FALSE
5 GTEx Brain Cortex KLHL24 0.21 0.15 lasso 3 0.07 6.1e-03 -5.2 5.7 1.3e-08 0.35 0.06 0.82 FALSE
6 GTEx Breast Mammary Tissue KLHL24 0.25 0.13 lasso 5 0.11 3.4e-06 -5.3 5.4 7.1e-08 0.30 0.06 0.93 TRUE
7 GTEx Esophagus Muscularis KLHL24 0.10 0.12 lasso 1 0.09 4.4e-06 -5.3 5.3 1.1e-07 0.25 0.06 0.94 FALSE
8 GTEx Lung YEATS2-AS1 0.13 0.03 enet 27 0.07 3.3e-06 5.6 -5.3 1.2e-07 -0.64 0.04 0.94 TRUE
9 GTEx Nerve Tibial KLHL24 0.08 0.06 lasso 3 0.05 1.5e-04 -5.3 5.3 1.3e-07 0.25 0.07 0.90 FALSE
10 GTEx Skin Sun Exposed Lower leg KLHL24 0.09 0.06 lasso 10 0.05 9.5e-05 -5.2 5.2 1.5e-07 0.24 0.06 0.93 FALSE
11 GTEx Testis KLHL24 0.17 0.10 lasso 4 0.10 4.0e-05 -5.3 5.3 1.1e-07 0.25 0.06 0.93 FALSE
12 METSIM Adipose MAP6D1 0.06 0.05 bslmm 473 0.06 2.3e-09 5.6 5.8 7.7e-09 0.68 0.07 0.93 TRUE