[Hub]/) : Traits : Leg fat mass (right) :

chr3:153,142,317-154,733,231

Best TWAS P=5.74e-10 · Best GWAS P=9.93e-11 conditioned to 0.000161

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX36 0.05 0.06 blup 357 0.05 1.3e-06 -4.7 -5.8 5.6e-09 0.58 0.94 0.06 FALSE
2 GTEx Ovary ARHGEF26 0.14 0.03 enet 15 0.06 1.4e-02 5.3 6.2 5.7e-10 -0.53 0.10 0.31 TRUE
3 GTEx Pancreas ARHGEF26 0.26 0.26 lasso 5 0.28 3.2e-12 -4.3 5.4 8.4e-08 -0.62 0.97 0.03 FALSE
4 GTEx Spleen DHX36 0.39 0.09 enet 21 0.34 2.1e-09 -3.6 -5.8 6.9e-09 0.58 0.67 0.25 FALSE
5 GTEx Thyroid ARHGEF26 0.09 0.07 enet 17 0.08 1.9e-06 -4.4 5.8 7.8e-09 -0.62 0.19 0.79 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SGEF 0.04 0.04 enet 12 0.04 1.1e-05 -4.6 5.7 1.1e-08 -0.63 0.11 0.86 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma DHX36 0.11 0.09 enet 11 0.10 6.4e-12 -4.7 -5.2 2.1e-07 0.37 0.83 0.16 FALSE