TWAS hub - CENPC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2240	0.0540	3.7e-07	0.036	NA	0.096	NA	0.086	5.6e-04	NA	2.8e-08	NA	1.6e-07
2	GTEx	Adipose Visceral Omentum	0.1020	0.0450	4.0e-03	0.043	NA	0.003	NA	0.038	2.7e-03	NA	2.3e-01	NA	4.5e-03
3	GTEx	Adrenal Gland	0.1761	0.0764	8.9e-03	0.012	NA	0.013	NA	-0.004	1.1e-01	NA	1.1e-01	NA	4.9e-01
4	GTEx	Artery Tibial	0.0974	0.0350	8.9e-04	0.014	NA	0.041	NA	0.016	2.6e-02	NA	3.6e-04	NA	1.8e-02
5	GTEx	Brain Hippocampus	0.2108	0.0749	8.6e-04	0.059	NA	0.070	NA	0.049	1.7e-02	NA	1.0e-02	NA	2.7e-02
6	GTEx	Breast Mammary Tissue	0.1500	0.0610	4.4e-03	0.002	NA	0.010	NA	0.012	2.5e-01	NA	9.5e-02	NA	7.1e-02
7	GTEx	Breast Mammary Tissue (Male)	0.1461	0.1045	1.3e-01	0.012	NA	-0.011	NA	0.014	1.7e-01	NA	7.3e-01	NA	1.5e-01
8	GTEx	Breast Mammary Tissue (Female)	0.1727	0.0873	3.9e-02	-0.007	NA	0.003	NA	-0.009	6.0e-01	NA	2.6e-01	NA	7.8e-01
9	GTEx	Cells EBV-transformed lymphocytes	0.1920	0.0630	3.3e-04	0.016	NA	0.032	NA	0.026	9.8e-02	NA	3.2e-02	NA	4.9e-02
10	GTEx	Cells Transformed fibroblasts	0.1230	0.0360	2.8e-07	0.119	NA	0.149	NA	0.171	3.1e-09	NA	2.8e-11	NA	7.1e-13
11	GTEx	Colon Transverse	0.1580	0.0590	3.5e-03	0.005	NA	0.012	NA	0.007	1.7e-01	NA	8.3e-02	NA	1.5e-01
12	GTEx	Esophagus Mucosa	0.1350	0.0440	1.3e-04	0.033	NA	0.083	NA	0.070	2.9e-03	NA	3.6e-06	NA	2.0e-05
13	GTEx	Muscle Skeletal	0.0868	0.0315	1.9e-04	0.023	NA	0.031	NA	0.037	2.3e-03	NA	4.2e-04	NA	1.5e-04
14	GTEx	Nerve Tibial	0.1959	0.0428	9.6e-12	0.134	NA	0.154	NA	0.179	1.0e-09	NA	5.2e-11	NA	9.6e-13
15	GTEx	Pituitary	0.2800	0.1040	8.3e-03	-0.011	NA	-0.002	NA	-0.012	7.7e-01	NA	3.7e-01	NA	9.0e-01
16	GTEx	Skin Not Sun Exposed Suprapubic	0.1050	0.0460	3.6e-03	0.111	NA	0.043	NA	0.083	1.2e-06	NA	2.2e-03	NA	2.6e-05
17	GTEx	Skin Sun Exposed Lower leg	0.1770	0.0470	1.8e-06	0.144	NA	0.147	NA	0.146	5.8e-12	NA	3.6e-12	NA	4.0e-12
18	METSIM	Adipose	0.0392	0.0173	6.4e-03	-0.002	0.009	0.002	0.008	0.001	7.9e-01	0.013	1.7e-01	0.019	2.0e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Pain type(s) experienced in last month: Hip pain	4.5	5.7	13.2	-3.6	-1.3	-2.4	-2.1	-0.8	-2.5	0.1	-2.8	-3.1	-1.9	-2.7	-3.2	-1.3	-1.7	-1.0	-2.6	-3.1	-3.1
Average weekly spirits intake	4.2	5.1	13.1	-2.5	-1.0	-2.5	-1.7	-1.8	-3.6	-1.7	-3.1	-2.1	-2.5	-2.5	-2.3	-2.2	-1.6	-1.5	-2.8	-2.6	0.5
Leg fat mass (right)	3.8	14.8	37.7	-6.1	-3.9	-2.2	-4.2	-2.7	-3.7	-0.3	-3.6	-3.7	-4.3	-2.7	-5.4	-3.2	-3.9	-1.4	-4.5	-5.4	-3.5
Leg fat mass (left)	3.5	13.8	33.3	-5.8	-3.9	-2.1	-4.0	-2.8	-3.6	-0.8	-3.4	-3.8	-4.5	-2.4	-5.2	-3.0	-4.1	-1.3	-4.1	-5.1	-3.0
Leg fat percentage (right)	3.4	12.2	34.8	-5.9	-3.3	-2.2	-4.2	-2.4	-3.0	-0.0	-3.2	-3.1	-3.7	-2.6	-4.7	-2.8	-3.2	-1.8	-4.0	-4.9	-3.5
Lung cancer (father)	3.3	3.8	9.3	-3.1	-1.2	-2.3	-1.9	-1.1	-1.6	-0.6	-1.6	-1.9	-1.7	-2.6	-2.5	-2.2	-1.1	-1.1	-1.9	-2.8	-2.0
Wheeze or whistling in the chest in last year	3.2	5.7	16.8	-3.1	-2.3	-2.4	-2.8	-1.3	-1.4	-0.3	-3.3	-2.5	-2.8	-1.1	-2.5	-4.1	-2.4	-2.2	-1.9	-2.1	-1.4
Shortness of breath walking on level ground	3.2	3.8	10.5	-2.1	-2.4	-3.2	-3.0	-1.7	-1.7	-0.6	-3.2	-1.9	-1.4	-1.4	-0.9	-2.3	-2.6	-0.2	-0.6	-1.0	-0.6
Arm fat mass (left)	3.2	13.0	29.4	-5.4	-4.1	-1.7	-3.9	-3.2	-3.2	-0.5	-3.1	-3.8	-4.5	-2.1	-5.0	-3.0	-4.4	-1.4	-3.8	-4.7	-2.8
Waist circumference	3.1	11.2	24.3	-4.9	-3.9	-2.1	-3.9	-2.9	-3.3	-0.2	-3.2	-4.1	-3.9	-2.2	-4.2	-2.7	-4.3	-1.4	-3.0	-4.0	-2.4
Medication: Amlodipine	3.1	4.3	17.0	-2.6	-3.2	-1.5	-4.1	-1.2	-0.5	-0.3	-2.9	-2.2	-1.3	-0.2	-2.3	-2.4	-2.5	-1.0	-0.4	-1.5	-2.0
Whole body fat mass	3.1	12.9	32.8	-5.7	-3.8	-1.9	-3.8	-3.1	-3.4	-0.2	-3.1	-3.7	-4.4	-2.4	-4.9	-2.9	-4.0	-1.3	-3.9	-4.8	-2.7
Medication: Aspirin	3.0	3.9	9.6	-3.1	-1.9	-2.1	-2.8	-1.8	-1.5	0.2	-1.9	-1.4	-1.9	-1.8	-2.7	-2.3	-1.7	-0.9	-1.8	-2.5	-1.5
Trunk fat mass	2.9	12.6	33.1	-5.8	-3.7	-1.9	-3.6	-3.3	-3.5	-0.5	-2.5	-3.5	-4.3	-2.6	-5.0	-2.7	-3.9	-1.3	-3.9	-5.0	-2.6
Hip circumference	2.9	12.5	23.8	-4.9	-4.0	-1.8	-3.6	-3.0	-3.9	-0.8	-3.4	-4.3	-4.8	-2.0	-4.5	-2.7	-4.5	-1.4	-3.9	-4.4	-2.2
Arm fat mass (right)	2.9	12.0	27.8	-5.3	-3.9	-1.6	-3.9	-3.1	-3.1	-0.4	-2.8	-3.6	-4.4	-2.2	-4.7	-2.8	-4.1	-1.3	-3.7	-4.6	-2.6
Commuting to job workplace: Public transport	2.9	3.4	13.4	1.7	3.4	-1.2	3.7	1.6	-0.6	-0.5	1.2	1.3	1.9	-0.2	2.0	1.8	2.5	0.9	0.9	1.3	2.5
Type 2 Diabetes (T2D) (2012)	2.8	3.2	9.1	-3.0	-1.6	-1.0	-2.4	-1.7	-0.9	-1.9	-1.9	-2.0	-1.2	-1.5	-2.7	-2.1	-1.1	-0.1	-0.8	-1.8	-1.9
Medication for pain relief, constipation, heartburn	2.8	4.8	12.9	3.3	1.4	2.8	2.5	1.8	2.3	1.0	2.2	2.1	2.8	1.7	1.9	3.6	2.4	0.6	1.7	1.9	-0.9
Knee pain experienced in last month	2.8	4.4	13.7	-3.4	-1.9	-0.2	-2.3	0.9	-1.9	-0.2	-3.7	-2.2	-1.6	-0.9	-2.5	-2.2	-2.0	-1.5	-2.0	-2.6	-1.7
Leg fat percentage (left)	2.8	10.1	27.8	-5.3	-3.0	-2.0	-3.8	-2.3	-2.8	-0.9	-2.8	-3.1	-3.8	-2.0	-4.3	-2.7	-3.3	-1.7	-3.5	-4.3	-2.6
Mean Putamen Volume	2.7	3.1	8.7	-1.7	-2.5	-0.5	-1.2	-1.6	-1.3	-0.8	-1.9	-3.0	-2.1	0.5	-1.8	-2.9	-1.8	-2.2	-1.3	-0.9	0.0
Body mass index (BMI)	2.7	11.7	25.9	-5.1	-3.8	-1.8	-4.0	-2.8	-3.1	-0.7	-3.3	-3.8	-4.4	-1.9	-4.3	-3.0	-4.2	-1.5	-3.8	-4.3	-2.4
Medication: Aspirin	2.7	3.5	8.0	-2.8	-1.6	-2.2	-2.7	-1.8	-1.4	0.3	-1.7	-1.5	-1.7	-1.9	-2.4	-2.4	-1.5	-1.0	-1.7	-2.2	-1.4
Number of operations (self-reported)	2.7	4.0	14.1	-3.4	-1.4	-1.3	-2.7	0.2	-3.7	-1.7	-2.4	-1.0	-1.2	-1.4	-1.4	-0.9	-1.4	1.0	-2.3	-3.2	-1.2
BMI	2.6	15.2	30.3	-5.5	-3.9	-3.0	-4.0	-3.0	-3.3	-0.8	-4.8	-4.4	-4.7	-1.7	-5.0	-4.8	-4.0	-2.4	-4.4	-4.6	-2.1
Body fat percentage	2.6	10.2	29.4	-5.4	-3.4	-1.7	-3.6	-2.7	-3.1	-0.3	-2.5	-3.2	-3.7	-2.4	-4.3	-2.3	-3.4	-1.3	-3.4	-4.5	-2.4
Medication: Blood pressure	2.6	4.6	11.5	-3.2	-1.8	-1.8	-3.4	-1.7	-2.4	-1.4	-1.8	-2.3	-2.1	-2.1	-2.3	-2.4	-2.2	-0.2	-2.1	-2.4	-0.6
Trunk fat percentage	2.5	10.1	27.9	-5.3	-3.6	-1.5	-3.5	-2.8	-3.2	-0.3	-2.2	-3.4	-3.6	-2.4	-4.3	-2.3	-3.5	-1.4	-3.2	-4.4	-2.2
Arm fat percentage (left)	2.5	9.8	23.8	-4.9	-3.6	-1.4	-4.0	-2.4	-2.5	0.2	-2.9	-3.5	-3.6	-1.9	-4.3	-2.5	-3.6	-1.7	-3.2	-4.0	-2.3
Ever taken oral contraceptive pill	2.5	2.8	12.5	0.3	2.3	0.6	1.7	0.8	0.4	1.0	1.9	3.5	1.9	-0.7	1.4	2.1	3.0	1.7	-0.6	0.0	0.3
Systolic blood pressure, automated reading	2.4	6.9	20.6	-3.9	-1.8	-0.1	-2.2	-1.1	-1.9	0.5	-2.5	-2.5	-3.8	-0.8	-4.5	-2.3	-2.6	-2.1	-3.5	-4.1	-1.0
Weight	2.4	11.9	26.5	-5.2	-3.5	-2.0	-3.4	-3.5	-3.4	-0.7	-2.9	-3.6	-4.5	-2.2	-4.6	-3.3	-4.1	-1.0	-3.8	-4.5	-2.4
Arm fat percentage (right)	2.4	9.7	24.1	-4.9	-3.5	-1.5	-4.0	-2.6	-2.6	0.1	-2.7	-3.5	-3.6	-2.4	-4.1	-2.2	-3.6	-1.4	-3.2	-4.1	-2.2
Hair/balding pattern: Pattern 3	2.4	3.6	13.0	-2.9	-0.3	0.3	-0.9	-0.3	-3.2	-0.8	-1.5	0.7	-1.5	-1.3	-3.3	-1.0	0.1	-0.4	-3.6	-3.3	-1.7
Number of full brothers	2.4	3.0	8.0	-1.7	-1.9	-0.4	-1.4	-1.2	-2.0	-0.1	-1.2	-1.3	-2.8	-0.5	-1.6	-2.0	-2.3	-2.3	-2.7	-1.8	0.2
Number of children fathered	2.4	2.7	8.8	-3.0	-1.4	-1.1	-2.4	-1.6	-0.9	-0.6	-1.7	-0.3	-0.9	-0.5	-2.0	-1.3	-1.0	2.2	-1.4	-1.9	-2.6
Wears glasses or contact lenses	2.4	2.8	8.9	-3.0	-0.5	-1.3	-2.2	-1.5	-0.9	-0.9	-0.9	-1.4	-0.7	-0.9	-2.4	-1.4	-0.7	-0.1	-2.0	-2.6	-2.8
Basal cell carcinoma (self-reported)	2.4	2.8	6.2	-1.2	-2.2	-1.9	-2.2	-2.3	-1.2	1.1	-1.9	-1.5	-1.0	-1.4	-2.5	-0.6	-2.2	-0.5	-1.5	-2.0	-1.0
Pack years adult smoking proportion	2.3	3.5	13.7	-1.5	-3.7	-0.3	-2.6	-1.8	-1.3	-0.2	-2.6	-2.7	-2.2	-0.1	-1.1	-1.4	-3.5	-0.2	-0.6	-1.1	-0.3
Long-standing illness, disability or infirmity	2.3	3.5	8.7	-2.2	-1.8	-2.8	-2.4	-0.1	-2.0	-1.7	-2.5	-3.0	-1.0	-1.2	-1.6	-2.3	-1.3	-1.5	-0.6	-1.1	-1.9
Osteoporosis (self-reported)	2.3	2.9	6.8	-1.9	-1.4	-1.9	-2.0	-1.1	-0.8	-0.9	-2.6	-1.9	-1.2	-1.2	-2.3	-2.5	-1.4	-2.1	-0.2	-1.8	-1.0
Heart attack	2.1	2.7	8.5	-2.9	-0.5	-2.0	-2.2	-0.0	-1.0	-1.0	-2.0	-1.5	0.4	-2.3	-1.9	-1.5	-0.2	-1.9	-0.3	-1.5	-2.5
Chronic bronchitis/emphysema (father)	2.0	2.4	6.2	-1.7	-2.3	-0.8	-2.5	-1.3	-0.3	0.8	-2.4	0.1	-1.6	-0.1	-1.5	-0.9	-2.2	0.4	-1.5	-1.8	-1.7
Illnesses of siblings: Diabetes	2.0	2.4	8.7	-1.1	-3.0	-1.2	-1.8	-0.8	-1.2	0.1	-2.3	-1.7	-1.4	-0.3	-1.5	-1.9	-2.0	-1.6	-1.3	-1.1	-0.8
Medication: Gliclazide	2.0	2.3	7.5	-0.9	-1.9	-0.4	-0.2	-2.1	-1.7	-0.7	-1.1	-2.6	-2.7	-0.6	-1.1	-0.9	-1.9	-0.8	-2.2	-1.3	0.3
Illnesses of father: None of the above (group 1)	2.0	2.5	11.2	1.1	2.4	0.8	1.9	1.9	0.6	3.3	2.1	1.1	1.4	-0.5	0.6	1.7	2.8	-0.4	0.2	0.2	0.5
Serious illness, injury or assault of a close relative in last 2 years	1.9	2.2	4.8	1.6	1.0	0.7	1.9	1.9	1.2	2.2	1.1	0.4	1.6	0.2	2.2	0.2	1.0	-0.8	2.0	2.1	1.5
Pack years of smoking	1.9	2.8	10.8	-1.6	-3.3	-0.7	-2.4	-1.4	-1.3	-0.7	-2.5	-2.5	-1.6	-0.1	-1.0	-0.9	-2.9	0.3	-0.5	-1.1	-0.8
Body Mass Index (BMI) (2010)	1.8	2.5	7.2	-2.1	-0.5	-1.9	-0.1	-0.4	-1.9	-0.6	-1.4	-1.2	-1.0	-2.6	-2.1	-1.4	-0.5	-2.7	-1.8	-1.8	-1.0
Hearing difficulty/problems: Yes	1.8	2.7	7.7	-1.9	-2.6	-0.8	-2.6	0.5	-2.0	-0.2	-2.8	-2.5	-1.3	0.2	-1.2	-1.6	-1.4	-0.1	-1.4	-1.4	-1.0
Medication: Omeprazole	1.8	2.1	6.4	-2.5	-0.5	-2.5	-2.2	-1.7	-0.5	0.5	-0.9	-1.4	-0.6	-1.8	-1.3	-1.8	-0.5	-1.1	-0.7	-1.6	-1.1
Commuting to job workplace: Car/motor vehicle	1.8	2.0	5.1	-1.1	-2.3	1.7	-2.1	-0.9	0.1	-0.9	-0.3	-2.0	-2.1	-0.2	-2.1	-1.1	-2.0	-1.4	-0.5	-0.6	-0.7
Ever had bowel cancer screening	1.8	2.1	5.8	-1.6	0.4	-1.8	-0.7	0.1	-2.4	-1.1	-0.5	-1.3	-1.2	-2.1	-1.9	-0.1	-0.6	-1.3	-2.3	-2.1	-0.7
Medication: Blood pressure	1.7	3.2	9.1	-3.0	-1.6	-0.8	-2.0	-1.3	-0.1	-0.8	-1.8	-2.8	-1.6	-0.6	-2.1	-2.9	-2.2	-1.2	-0.1	-1.2	-1.9
Ever had prostate specific antigen (PSA) test	1.7	1.9	5.2	-2.1	2.2	-0.7	-0.5	-0.2	-2.0	0.0	-0.1	0.6	-0.8	-2.3	-1.5	0.6	0.7	-1.3	-1.9	-2.2	-1.0
Arm predicted mass (left)	1.7	8.5	17.1	-3.9	-3.1	-1.7	-2.5	-3.4	-2.5	-1.3	-2.3	-3.0	-4.1	-1.9	-3.9	-3.0	-3.8	-0.5	-2.9	-3.6	-1.8
Bilateral oophorectomy (both ovaries removed)	1.6	1.8	3.6	-1.6	-1.9	-0.6	-1.9	-0.5	-1.4	0.4	-1.4	-0.9	-0.7	-1.2	-1.8	-1.4	-1.7	0.9	-0.6	-1.8	-1.8
Medication: Lansoprazole	1.6	1.8	8.4	-0.8	-1.5	0.3	-2.9	-0.2	0.6	-0.2	-2.5	-2.3	-0.3	-1.3	-1.1	-1.4	-1.6	-1.5	0.7	0.1	-0.3
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	11.0	2.5	2.1	0.9	3.3	2.5	-0.9	0.6	1.5	-0.3	0.7	0.0	0.6	1.4	1.9	-0.2	0.3	1.4	2.4
Number of full sisters	1.6	2.0	6.1	1.7	1.5	-0.7	1.4	0.2	1.5	-0.4	1.2	0.5	0.9	1.2	2.5	1.9	0.5	1.3	1.6	1.9	1.9
Age at First Birth	1.5	2.2	5.6	2.4	2.2	2.0	1.0	2.1	0.7	0.2	1.0	1.3	1.3	0.7	1.4	1.6	2.3	-1.2	0.4	1.4	0.8
Overall health rating	1.5	3.2	15.2	-2.3	-0.7	-3.9	-1.4	0.6	-1.8	-1.3	-2.5	-2.3	-1.1	-1.3	-0.9	-1.6	-1.6	-2.3	-0.8	-1.7	-0.9
Leg pain on walking	1.5	1.9	8.8	-2.0	-1.4	-1.6	-0.7	0.1	-1.5	-0.9	-3.0	-0.1	-0.4	-0.8	-1.4	-1.0	-1.2	-1.1	-1.2	-1.3	-2.1
Medication: Lisinopril	1.5	2.0	8.4	-2.2	-1.0	-0.9	-2.3	-1.4	0.3	-1.3	-1.5	-1.1	-0.3	-1.1	-1.6	-2.9	-0.5	-0.8	-0.0	-1.0	-1.3
Commuting to job workplace: Cycle	1.5	1.8	4.7	2.2	0.6	-0.9	1.9	-0.3	-0.2	1.3	2.0	0.9	1.5	-1.5	1.7	1.7	0.6	1.1	1.7	1.0	0.3
Heart attack/myocardial infarction (self-reported)	1.5	1.9	5.8	-2.4	-0.2	-1.6	-2.0	-0.2	-0.9	-1.2	-1.5	-1.3	0.3	-1.9	-1.5	-1.3	-0.2	-1.7	-0.1	-1.2	-2.0
Stomach or abdominal pain in last month	1.4	1.7	5.3	-1.5	1.3	-1.0	-0.9	1.4	-1.7	-2.3	-1.4	0.5	0.4	0.2	-0.8	0.8	1.1	0.9	-1.6	-1.4	-2.1
Medication: Paracetamol	1.4	2.3	6.3	-1.7	-1.5	-1.3	-2.0	-0.8	-1.2	-2.5	-0.7	-1.4	-1.7	-0.9	-0.7	-2.5	-2.3	1.0	-0.3	-0.7	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.6	4.4	1.0	1.6	1.3	2.0	1.9	0.5	-0.2	1.6	1.5	0.3	2.1	1.6	1.4	1.1	-0.4	-0.0	0.9	0.8
Smoking status: Previous	1.4	2.0	6.9	-1.3	1.9	0.2	0.8	1.3	-0.2	1.3	0.4	1.3	2.2	-1.1	-0.6	2.6	1.9	-1.3	-0.2	-1.3	-2.2
Osteoarthritis (self-reported)	1.4	1.8	5.7	-1.9	-0.7	-2.2	-0.2	-0.8	-2.4	-0.8	-1.3	-1.4	-1.6	-1.0	-1.1	-1.0	-1.6	-0.6	-1.3	-1.5	-0.4
Basal metabolic rate	1.4	7.7	16.0	-3.7	-3.0	-1.6	-2.3	-3.1	-2.5	-0.7	-2.4	-2.9	-4.0	-1.9	-3.7	-2.9	-3.6	-0.5	-3.0	-3.5	-1.7
Arm fat-free mass (left)	1.4	7.0	14.2	-3.5	-2.7	-1.7	-2.2	-3.2	-2.4	-1.4	-2.1	-2.8	-3.8	-1.8	-3.4	-2.7	-3.5	-0.3	-2.6	-3.2	-1.5
Diastolic blood pressure, automated reading	1.4	4.3	10.8	-3.3	-1.0	-0.1	-1.7	-0.7	-1.6	1.2	-1.6	-2.4	-3.0	-1.8	-3.3	-1.1	-2.0	-0.1	-2.8	-3.1	-2.0
Primary Biliary Cirrhosis	1.3	1.8	5.9	1.5	-0.4	2.1	0.1	1.1	1.8	0.1	0.7	-0.3	1.4	-0.4	2.2	0.3	-0.1	1.7	2.0	2.4	0.7
Leg fat-free mass (left)	1.3	6.7	12.5	-3.4	-3.0	-1.4	-2.3	-2.7	-2.3	0.1	-2.2	-3.1	-3.5	-2.0	-3.4	-2.8	-3.3	-0.7	-2.7	-3.1	-1.5
Leg predicted mass (left)	1.3	6.7	12.3	-3.3	-3.0	-1.4	-2.3	-2.6	-2.3	0.1	-2.3	-3.1	-3.5	-2.0	-3.4	-2.9	-3.2	-0.8	-2.7	-3.1	-1.5
Had menopause	1.3	1.6	4.2	-1.6	-1.5	-2.0	-0.3	-1.8	-1.9	-1.2	-1.1	-0.1	-1.1	-0.2	-1.2	-0.7	-1.2	0.6	-1.2	-1.7	-0.9
Qualifications: A levels/AS levels or equivalent	1.3	3.0	10.4	3.2	2.0	-0.2	3.2	-0.5	-1.4	-0.6	2.2	0.8	0.4	-1.7	1.4	1.3	1.2	0.5	0.5	1.7	3.0
Length of working week for main job	1.3	1.4	5.6	0.9	0.9	0.2	0.5	0.3	1.4	1.4	0.7	1.0	2.4	0.0	1.3	1.0	1.6	1.0	1.8	1.6	0.4
Illnesses of father: Heart disease	1.3	1.8	12.6	-0.9	0.1	-2.0	-2.1	-1.2	0.1	-3.5	-1.2	-0.1	1.1	-1.2	-0.1	-0.8	-0.5	0.1	0.8	-0.0	-1.9
Supplements: Calcium	1.3	1.4	5.1	-0.9	1.6	-0.6	2.3	-0.2	-1.3	-0.6	-0.0	-0.2	-1.8	-0.6	-1.5	0.4	0.1	-1.4	-1.7	-1.8	0.7
Alcohol drinker status: Previous	1.3	1.5	5.2	-0.9	-1.3	-0.5	-0.3	0.4	-1.6	0.2	-1.7	-1.1	-0.3	-1.3	-2.3	0.6	-1.1	-2.3	-0.5	-1.6	-0.8
Relative age of first facial hair	1.2	2.6	8.6	2.4	1.3	0.7	0.7	0.1	1.8	-0.5	2.2	0.7	0.6	1.0	2.9	0.9	-0.0	0.3	2.3	2.5	2.5
Ever had hysterectomy (womb removed)	1.2	1.4	4.3	-0.8	-0.7	-0.9	-0.4	-2.0	-0.9	-1.5	0.6	-0.9	-1.9	-0.5	-1.3	-1.5	-2.1	0.1	-0.3	-0.9	-1.5
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	4.5	2.1	0.4	2.0	1.0	0.7	0.0	0.5	0.5	0.4	0.0	1.0	2.0	0.9	-0.5	1.9	0.9	1.7	2.0
Arm fat-free mass (right)	1.2	6.0	12.5	-3.4	-2.7	-1.4	-1.8	-2.6	-2.2	-1.0	-2.1	-2.4	-3.5	-1.2	-3.3	-2.8	-3.2	-0.4	-2.4	-3.0	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.3	5.5	-0.6	0.4	-1.4	-1.3	0.1	-0.7	-2.2	-1.3	-1.2	0.3	-0.4	-0.4	-2.1	0.1	-2.3	0.8	0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	7.6	1.4	1.2	1.8	0.1	1.8	2.8	0.5	0.1	1.4	2.2	0.5	2.4	2.3	1.8	1.5	1.2	1.5	0.8
Illnesses of father: High blood pressure	1.2	1.5	5.7	-0.3	-1.7	0.3	-1.6	-1.4	-0.6	-1.4	-1.0	-1.7	-1.4	0.3	-0.6	-1.7	-2.4	1.0	0.7	0.9	0.8
Myopia	1.2	1.7	6.6	0.7	1.4	0.3	2.6	-0.1	-1.1	-0.2	2.5	0.5	-1.3	1.7	0.3	1.4	0.3	0.2	-1.7	-0.4	1.9
Vascular/heart problems diagnosed by doctor	1.2	3.2	10.0	3.2	0.3	1.5	2.8	1.7	1.5	1.3	1.2	1.9	1.3	2.5	1.5	2.8	1.5	1.1	0.9	1.4	0.5
Major Depression (MDD)	1.1	1.3	3.9	0.8	0.4	0.9	-0.5	1.2	0.5	-0.3	1.2	0.9	1.4	2.0	1.9	1.5	1.2	0.9	0.5	0.7	-1.5
Allergy or Eczema	1.1	2.8	11.0	3.3	0.2	1.4	2.0	0.5	-0.8	-0.8	0.8	-1.4	-0.0	-0.1	2.4	2.5	-1.1	2.0	0.9	2.6	2.0
Current tobacco smoking	1.1	1.9	6.8	-1.1	-1.4	-1.5	-1.9	-1.2	-0.7	-0.6	-0.9	-1.4	-1.1	-1.4	-0.7	-2.6	-1.9	-2.3	0.6	-0.2	0.3
Taking other prescription medications	1.1	1.7	6.6	-1.7	-1.7	-0.4	-2.5	0.7	0.4	0.3	-2.6	-1.7	-0.1	-0.7	-1.2	-1.5	-0.8	-1.3	0.5	-0.4	-1.3
High blood pressure (mother)	1.1	1.6	4.5	-1.4	-1.7	0.4	-1.3	-0.4	0.0	1.1	0.1	-2.1	-1.8	-0.2	-1.7	-1.5	-2.1	-0.0	-0.9	-1.0	-0.7
Diabetes (self-reported)	1.1	1.7	5.9	-0.5	-2.0	-1.4	-1.1	-1.8	-0.2	-0.9	-0.8	-2.2	-1.0	0.4	-0.7	-2.4	-1.4	-1.7	0.3	0.1	-0.7
Fluid intelligence score	1.1	2.2	9.2	0.1	2.9	-0.9	2.1	1.4	-1.5	0.4	0.5	1.9	1.1	-2.3	-0.0	1.1	3.0	0.6	-0.9	-0.1	-0.3
Blood clot in the leg (DVT)	1.1	1.5	5.3	-2.2	-0.2	-1.2	-1.5	0.6	-1.1	0.5	-1.4	0.5	1.0	-1.6	-0.3	-0.0	0.8	0.9	-1.2	-1.4	-2.3
Health satisfaction	1.1	1.4	8.3	-0.8	-1.4	-1.4	-1.1	-0.6	-1.6	-0.9	-2.9	-1.1	-1.1	-0.9	0.1	-1.1	-1.5	-0.7	-0.7	-0.2	0.0
Arm predicted mass (right)	1.1	5.6	11.6	-3.4	-2.5	-1.6	-1.8	-2.5	-2.0	-1.1	-2.2	-2.1	-3.3	-1.2	-3.2	-2.6	-3.0	-0.5	-2.3	-3.0	-1.8
Whole body water mass	1.1	6.1	12.9	-3.2	-2.6	-1.6	-1.9	-2.9	-2.3	-0.9	-2.1	-2.5	-3.6	-1.7	-3.3	-2.5	-3.3	-0.4	-2.6	-3.0	-1.4
Hearing aid user	1.1	1.2	4.5	-2.1	0.3	1.2	-0.1	0.4	-0.9	0.4	-0.2	0.7	-1.1	0.5	-1.4	-0.4	0.2	-1.3	-1.7	-2.1	-1.1
Medication: Bendroflumethiazide	1.1	1.6	6.4	-1.5	-1.3	-0.2	-1.1	-1.2	-0.9	-1.2	-0.7	-2.5	-1.6	-0.8	-1.6	-1.3	-1.9	0.7	-0.5	-0.5	-0.9
Medication: Paracetamol	1.1	1.7	6.4	-1.2	-1.2	-1.1	-1.9	-1.0	-1.1	-2.5	-0.9	-1.0	-1.4	-0.6	-0.6	-1.4	-1.9	1.7	-0.4	-0.5	0.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.5	-1.9	-0.7	-2.1	-1.7	-0.8	-0.1	0.6	-0.9	-1.6	-0.4	-1.4	-1.1	-1.4	-0.4	-1.0	-0.3	-1.2	-0.8
Lung FEV1/FVC ratio	1.0	5.0	14.1	-3.0	-0.9	0.5	-2.6	-2.2	-2.0	-0.5	-1.5	-1.4	-3.1	-2.1	-3.3	-1.6	-1.7	-2.4	-3.1	-3.8	0.3
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	6.7	-0.9	0.6	-2.6	-0.2	0.8	-1.4	-0.7	-1.3	-0.2	0.5	-1.9	-0.8	-0.6	0.6	-2.1	-0.0	-0.4	-0.5
Medication: Co-codamol	1.0	1.2	3.8	-0.2	-1.9	-1.5	-1.0	-1.4	-0.8	-1.3	0.1	-1.2	-1.1	-0.1	-0.0	-1.4	-1.9	0.9	0.3	0.0	-0.4
Hayfever, allergic rhinitis or eczema	1.0	2.1	5.6	2.4	-0.5	2.0	1.4	0.3	-1.8	-0.2	0.9	-1.8	-0.9	-0.3	1.4	1.8	-1.6	1.7	-0.2	1.6	2.1
Medication: Atenolol	1.0	1.3	3.6	-1.9	-0.7	-0.9	-1.8	-0.9	-0.8	-0.5	-0.6	-0.4	-0.8	-0.7	-1.6	-1.1	-1.1	-1.2	-0.6	-1.5	-1.5
Hearing difficulty/problems with background noise	1.0	1.7	4.4	-1.7	-1.5	-0.6	-1.1	0.3	-2.1	-1.1	-1.5	-1.8	-1.6	-0.1	-1.1	-0.7	-1.1	0.5	-1.7	-1.5	-1.2
Forced vital capacity (FVC)	1.0	3.7	9.4	1.1	1.3	1.3	1.2	2.0	2.5	-0.4	1.0	2.5	3.1	2.0	2.4	2.1	2.5	2.6	1.5	1.3	-1.1
Qualifications: None of the above	1.0	2.2	10.0	-3.2	-1.0	-0.6	-3.0	-0.8	0.3	-0.3	-1.6	-0.2	-0.3	-0.3	-1.2	-2.0	-1.3	-0.5	0.1	-1.2	-2.6
Pulse rate	1.0	1.6	5.2	-1.6	-2.1	-0.6	-0.7	-1.4	-1.1	-0.4	-0.2	-2.0	-1.2	-0.9	-1.1	-0.2	-1.6	2.3	-1.1	-1.0	-0.7
Prospective memory result	1.0	1.2	6.3	-0.2	-2.1	-0.5	-1.7	-0.9	0.8	0.9	0.1	-1.5	-1.3	-0.4	-0.6	0.1	-2.5	-0.1	-0.4	-1.0	-0.3
Illnesses of mother	1.0	1.3	3.6	1.0	1.5	1.2	1.8	0.5	-1.0	0.6	0.9	1.9	0.7	0.2	0.7	1.7	1.1	1.2	-0.0	0.1	1.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.7	1.6	-0.0	-0.9	1.0	0.6	0.2	-1.5	1.0	-0.4	0.8	1.1	1.9	0.6	-0.3	1.2	1.9	1.8	1.2
Headache pain in last month	1.0	1.8	5.8	-1.1	1.4	-1.9	0.3	0.6	-2.4	-1.9	-0.3	1.5	-0.1	-1.1	-0.5	0.9	0.9	1.6	-2.3	-1.5	-0.2
Whole body fat-free mass	1.0	5.8	12.7	-3.1	-2.5	-1.5	-1.8	-2.8	-2.2	-0.9	-2.1	-2.4	-3.6	-1.7	-3.1	-2.6	-3.1	-0.3	-2.6	-3.0	-1.3
Leg fat-free mass (right)	1.0	5.4	12.3	-2.7	-2.8	-1.1	-1.9	-2.7	-2.1	-0.3	-1.9	-2.9	-3.5	-1.6	-2.9	-2.8	-3.3	-0.4	-2.2	-2.5	-0.8
Leg predicted mass (right)	1.0	5.4	12.2	-2.7	-2.8	-1.2	-1.9	-2.6	-2.1	-0.4	-1.9	-2.9	-3.5	-1.6	-2.9	-2.8	-3.3	-0.5	-2.2	-2.5	-0.8
Mother’s age at death	1.0	1.3	5.8	0.6	2.1	0.6	2.4	0.4	-1.2	-0.3	1.8	-0.1	-0.4	-1.3	0.0	1.2	1.1	-0.8	-1.0	-0.2	1.2
Unable to work because of sickness or disability	1.0	1.3	4.2	0.2	-0.0	-2.0	-0.8	1.6	0.3	-1.3	-1.4	0.0	1.9	-0.2	0.9	-0.6	0.6	-0.7	2.0	1.3	-0.9
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.8	-2.2	0.1	-0.8	-1.1	0.7	-1.4	0.5	-1.2	0.6	0.7	-1.4	-0.4	0.2	1.0	0.9	-1.6	-1.6	-1.7
Angina	0.9	1.2	9.7	-1.3	-0.9	-1.4	-3.1	-0.8	-0.2	0.1	-0.6	0.0	0.2	-2.0	0.1	-1.2	-0.7	-0.2	-0.1	-0.5	-0.5
Severe depression (siblings)	0.9	1.0	4.0	1.0	-0.7	-0.7	0.5	0.8	0.5	2.0	0.2	0.5	0.8	-0.0	1.6	-0.3	-0.2	1.5	1.6	1.4	0.8
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	4.9	-1.0	0.4	-2.2	-0.3	-0.7	-0.0	-1.7	-0.8	-0.7	-1.0	0.7	-0.7	-0.1	0.0	-2.1	-0.8	-0.1	-1.0
Number of incorrect matches in round	0.9	1.6	4.1	-0.8	-0.9	-0.6	-0.4	-2.0	-0.6	0.7	-0.4	-1.8	-1.9	-1.2	-1.8	-0.6	-1.9	-1.1	-1.1	-1.6	0.8
Had other major operations	0.9	1.1	4.1	-0.5	-0.7	-2.0	-0.7	-1.2	-1.1	-1.0	-1.1	-1.1	-0.8	-1.7	0.5	-0.8	-1.5	0.7	-0.6	-0.6	0.5
Trunk fat-free mass	0.9	5.0	11.9	-2.9	-1.9	-1.5	-1.6	-2.8	-2.0	-1.0	-1.8	-1.7	-3.5	-1.6	-3.1	-2.3	-2.9	-0.0	-2.6	-3.0	-1.4
Father’s age at death	0.9	1.2	5.5	1.2	0.8	2.3	1.6	-0.3	-0.4	0.1	2.4	0.4	-1.2	0.3	-0.2	1.4	-0.2	1.2	-0.7	0.1	0.9
Mouth/teeth dental problems: Dentures	0.9	1.6	7.5	-1.9	-1.8	-0.7	-2.7	0.1	-0.1	-0.6	-1.9	-0.6	0.2	-1.4	-0.9	-1.5	-1.0	-0.3	0.1	-1.0	-1.5
Trunk predicted mass	0.9	4.9	11.7	-2.9	-1.8	-1.5	-1.5	-2.7	-2.0	-1.0	-1.7	-1.7	-3.4	-1.6	-3.1	-2.2	-2.8	-0.1	-2.7	-3.0	-1.4
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	5.1	1.8	0.9	1.5	2.3	1.3	1.2	1.7	0.1	1.4	0.5	1.6	0.6	1.4	0.8	-0.6	0.2	0.7	0.7
Gout (self-reported)	0.9	1.2	3.7	1.1	-1.2	-0.1	-0.7	0.9	1.2	-1.3	0.5	-0.4	1.0	1.1	1.4	-1.4	0.0	-0.2	1.9	1.9	0.7
Qualifications: College or University degree	0.9	2.8	11.6	2.7	0.1	-1.1	2.8	-2.5	-1.6	-0.2	1.5	-1.0	-1.8	-1.0	0.7	0.9	-1.2	1.5	-0.7	0.9	3.4
Medication: Allopurinol	0.9	1.2	5.7	0.3	-1.4	-0.6	-0.9	-0.5	0.9	-1.9	0.1	-1.0	-0.1	0.3	0.3	-2.4	-0.8	-1.5	1.4	1.0	1.1
Medication: Seretide 50 evohaler	0.9	1.1	4.5	-2.1	-0.1	-0.1	-1.6	-0.3	-1.5	1.6	-0.5	0.5	-0.8	0.0	-0.7	-0.4	-0.6	-0.2	-1.0	-1.6	-1.2
Heart disease (mother)	0.9	1.1	5.1	-0.6	-1.6	-1.2	-0.9	-1.2	1.3	-0.1	-0.9	-2.3	-0.8	-0.4	-0.7	-1.0	-1.3	-0.3	0.3	0.1	-1.1
Handedness (chirality/laterality): Left-handed	0.9	1.0	5.8	1.3	-0.3	0.6	0.9	-0.5	1.2	-0.8	0.9	-0.4	-0.3	1.9	0.8	2.4	-0.7	0.9	0.5	0.7	0.4
Qualifications: nursing, teaching	0.9	1.4	3.9	0.3	0.6	-0.6	1.7	-1.1	-2.0	0.4	1.4	-0.7	-1.7	-1.0	-0.9	1.1	-0.5	-0.0	-1.7	-0.9	1.9
Eye problems/disorders: Cataract	0.9	1.0	2.5	-0.6	-1.3	0.7	-1.4	-0.2	-0.3	-0.3	-1.3	-1.3	-0.7	-1.4	-1.6	0.1	-1.0	-1.3	-1.1	-1.2	-0.7
Smoking status: Current	0.9	1.4	6.0	-0.8	-1.0	-1.1	-1.6	-1.0	-0.4	-0.1	-0.6	-1.1	-0.9	-1.3	-0.3	-2.5	-1.5	-2.3	0.6	0.0	0.8
Guilty feelings	0.9	1.3	5.5	-0.5	-2.3	-0.8	-1.5	-1.3	0.2	0.1	-1.0	-1.7	-1.2	-0.5	-0.2	-1.6	-2.3	-0.2	0.2	-0.5	-0.3
Alcohol drinker status: Never	0.9	1.1	5.0	-0.4	-1.5	0.5	-2.2	-1.2	-0.9	-0.8	-1.3	-0.8	-1.3	0.7	0.2	-0.2	-1.6	0.7	-0.7	-0.3	-0.7
Ever depressed for a whole week	0.9	1.1	4.2	1.1	2.0	-0.4	0.8	1.3	1.1	-1.2	0.6	0.4	0.6	0.9	1.6	0.3	1.3	-0.5	1.1	1.2	-0.0
Cholesterol lowering medication	0.9	1.3	5.4	-0.6	-0.9	-2.0	-0.3	-0.6	-0.2	-0.4	-2.3	-1.5	-0.5	-1.1	-0.5	-1.7	-0.7	-1.6	-0.2	-0.1	-1.3
Impedance of whole body	0.9	4.8	9.8	2.5	2.4	1.5	2.2	1.4	1.6	0.7	3.1	2.5	3.0	0.9	2.8	2.4	2.7	1.0	2.6	2.3	1.7
Alzheimer’s Disease (in father)	0.8	0.8	4.5	0.4	0.3	-0.0	0.7	0.4	0.9	0.3	1.4	0.1	0.7	-0.2	0.9	-0.7	0.4	0.9	2.1	1.4	1.4
Ulcerative Colitis (UC)	0.8	1.5	5.2	1.6	0.1	1.0	-0.6	0.2	2.0	-0.2	0.1	-0.8	1.0	1.4	1.5	-0.7	-0.1	-0.2	2.3	2.3	1.0
Verbal and Numeric Reasoning (VNR)	0.8	1.9	6.9	1.2	2.0	-0.9	2.6	1.5	-1.2	0.1	-0.3	1.7	1.2	-1.3	0.6	1.6	2.4	-0.3	0.2	0.6	1.0
Neuroticism (2016)	0.8	1.2	4.6	-0.6	-1.5	-0.6	-0.7	-0.5	-1.3	1.5	0.2	-0.8	-2.2	-0.2	-0.4	-1.3	-1.4	-0.7	-1.6	-0.9	1.1
Schizophrenia (2014)	0.8	1.7	9.0	0.8	1.1	0.7	1.4	-1.3	0.1	-1.4	3.0	0.7	-0.7	2.1	1.2	0.1	-0.8	1.8	0.5	0.7	1.5
Type 2 Diabetes (T2D) (2018)	0.8	1.5	5.0	-0.4	-2.1	-0.8	-2.0	-0.4	1.3	-0.1	-1.2	-0.1	1.3	1.4	0.1	-2.0	-0.2	-0.2	1.3	0.7	-2.2
Lung FVC	0.8	4.3	13.5	1.1	0.5	1.8	-0.5	2.9	2.9	0.8	0.1	2.3	3.7	1.5	2.9	2.4	2.6	2.1	1.9	1.7	-1.4
Chronotype (morning person)	0.8	1.8	7.7	1.2	-0.8	1.9	0.3	1.3	1.5	-1.6	0.3	0.5	1.0	2.8	1.7	-0.1	0.3	1.3	1.5	1.9	0.4
Supplements: Zinc	0.8	0.9	5.8	0.7	-0.1	1.3	1.4	-0.2	-0.4	-0.4	1.3	0.2	-0.8	1.0	0.7	-0.8	-0.3	-0.3	0.5	0.7	2.4
High blood pressure	0.8	2.3	7.3	-2.7	-0.4	-0.9	-2.6	-1.6	-1.2	-1.5	-1.0	-1.6	-1.4	-1.6	-1.2	-2.6	-1.7	-0.7	-0.4	-1.0	-0.6
Medication: Levothyroxine sodium	0.8	1.3	7.1	1.1	-0.2	2.7	0.2	1.6	0.1	0.7	-0.4	1.4	2.0	0.1	0.9	1.2	0.9	-0.2	0.8	1.1	0.2
Impedance of leg (left)	0.8	4.1	8.7	2.3	2.2	1.4	2.2	1.2	1.4	-0.6	2.9	2.4	2.5	0.8	2.6	2.1	2.3	1.2	2.5	2.1	1.7
Hair/balding pattern: Pattern 2	0.8	1.0	3.1	1.1	0.8	-0.0	0.5	0.6	1.4	0.4	0.4	1.3	1.6	-0.1	1.8	0.6	0.9	0.9	1.5	1.1	0.2
Impedance of arm (left)	0.8	3.8	7.8	2.4	1.9	1.4	1.8	1.5	1.4	1.3	2.4	2.0	2.8	0.9	2.4	2.1	2.5	0.5	2.3	2.2	1.7
Exposure to tobacco smoke outside home	0.8	1.0	4.9	-1.6	-0.2	-0.8	-2.2	0.3	-0.1	0.1	-1.6	-0.4	-0.7	-1.0	-1.0	-1.7	-0.9	-0.1	-0.4	-0.8	-0.1
Eye problems/disorders: None of the above	0.8	0.9	2.8	0.8	1.0	-0.8	1.4	-0.9	0.3	1.6	1.7	1.3	-0.0	0.8	0.7	0.1	0.6	1.1	-0.0	0.5	1.3
Angina (self-reported)	0.8	1.0	8.5	-1.0	-0.6	-1.4	-2.9	-0.5	0.1	0.3	-0.6	0.5	0.7	-1.7	0.4	-1.1	-0.1	-0.3	0.2	-0.2	-0.7
Had major operations	0.8	1.0	3.4	-1.8	0.0	0.1	-1.8	1.0	-1.0	-0.7	-1.7	0.8	-0.3	0.2	-0.3	-0.1	0.0	-0.5	-1.1	-1.8	-0.4
Hypertension (Self-reported)	0.8	2.1	7.1	-2.7	-0.6	-0.8	-2.4	-1.7	-1.0	-0.9	-0.7	-1.2	-1.4	-1.6	-1.2	-2.5	-1.7	-0.5	-0.6	-1.1	-1.0
High cholesterol (Self-reported)	0.8	1.4	3.3	0.5	1.1	0.6	-0.0	-0.6	1.6	-0.5	1.5	1.8	1.4	1.3	1.0	0.4	1.4	1.5	1.6	1.4	-1.1
Intelligence (Savage-Jansen 2018)	0.7	2.3	5.1	2.0	1.8	-0.5	2.2	1.0	-1.0	-0.1	0.0	1.5	1.9	-2.0	1.3	2.2	2.3	-0.1	0.7	1.3	1.5
Schizophrenia vs Biploar Disorder	0.7	0.9	3.0	1.1	-1.2	1.0	0.6	-0.9	0.7	0.9	1.2	-0.9	-1.7	0.2	-0.3	0.6	-1.7	-0.1	-0.6	-0.1	1.1
Ovarian Cancer	0.7	1.0	2.9	-0.7	-0.4	-0.5	-1.4	-0.7	-0.6	1.1	-1.1	-0.9	-0.3	-1.7	-1.2	-1.2	-0.2	-0.7	-1.2	-1.4	-0.7
Bipolar Disorder (2011)	0.7	0.7	4.4	0.8	1.1	-0.4	-0.2	0.2	-1.1	0.0	-0.1	0.1	1.0	-2.1	0.9	0.3	1.0	0.6	0.0	0.2	1.0
Fasting Glucose	0.7	0.9	4.1	-0.4	1.6	-2.0	0.8	0.8	-0.0	-1.1	-0.1	-0.2	0.9	-1.4	-0.3	-0.6	1.0	-1.2	0.1	-0.3	-0.4
Lupus	0.7	1.0	4.1	0.7	-1.6	1.0	0.1	-0.7	0.6	-0.3	0.6	-1.9	-0.6	0.1	-0.1	-2.0	-1.2	-0.7	0.8	0.0	1.5
Ulcerative Colitis	0.7	1.0	2.5	1.3	-1.0	0.4	-0.6	0.2	1.3	-0.0	0.4	-1.4	-0.2	1.6	0.7	-1.0	-0.6	-0.8	1.1	1.6	1.5
Hypothyroidism (self reported)	0.7	1.5	6.8	0.4	-0.5	1.3	0.5	1.8	0.9	0.2	-0.5	1.7	2.6	0.7	0.5	1.8	1.3	0.7	1.1	0.6	-1.8
Number of treatments/medications taken	0.7	1.2	4.2	-1.2	-1.7	-0.6	-2.1	-0.4	-0.1	-0.1	-2.0	-1.7	-0.0	-0.3	-0.6	-1.5	-1.0	0.5	1.0	0.4	-1.0
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.0	0.8	-1.4	-0.3	-0.9	0.7	0.8	-0.0	-0.9	-0.6	0.6	0.8	0.9	-1.0	-0.8	-0.9	1.1	1.3	-0.6
Medication for hormone replacement therapy	0.7	0.7	2.0	1.1	-0.3	1.0	0.5	-0.7	0.7	-1.4	0.4	0.7	0.8	0.9	1.0	0.7	0.5	1.0	1.2	1.1	0.3
Serious illness, injury or assault to yourself	0.7	0.8	4.4	-0.2	-1.1	-2.1	-0.9	-0.9	-0.6	0.7	-0.5	-0.7	-0.7	-1.3	-0.4	-1.2	-1.1	-0.1	0.2	-0.5	-0.5
Past tobacco smoking	0.7	1.3	3.6	1.5	-1.4	0.1	-0.1	-0.9	0.3	-1.1	-0.4	-0.8	-1.9	1.5	0.5	-1.7	-1.3	1.4	-0.1	1.1	1.6
Impedance of arm (right)	0.7	3.2	7.0	2.1	1.8	1.4	1.5	0.7	1.2	1.3	2.6	1.8	2.3	0.1	2.3	2.3	2.2	1.0	1.7	1.8	1.8
Alcohol intake versus 10 years previously	0.7	1.0	5.3	-0.6	1.0	0.6	-0.2	2.3	0.9	-0.0	-0.2	1.4	1.2	0.9	0.6	0.3	1.1	1.2	0.6	0.4	-1.5
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	5.2	0.8	1.0	1.9	0.9	1.7	2.2	0.0	1.0	2.3	2.1	1.7	1.9	1.7	1.8	2.2	0.8	0.7	-0.2
Medication: Cholesterol lowering	0.7	1.1	4.9	0.3	0.2	-0.9	-0.7	-0.5	1.4	-0.7	1.3	-0.2	1.8	-0.3	1.5	-0.3	1.0	0.9	2.2	1.5	-0.3
Exposure to tobacco smoke at home	0.7	0.8	2.6	-0.4	1.6	1.5	0.1	0.4	1.0	0.0	0.5	1.5	0.7	1.2	0.7	0.4	1.6	0.2	0.2	0.6	-0.6
Breastfed as a baby	0.7	0.8	3.7	0.3	0.7	-1.9	0.4	0.6	0.9	-0.3	-1.1	0.9	1.5	0.4	0.5	0.2	0.8	-0.5	1.4	0.5	-1.1
Peak expiratory flow (PEF)	0.7	1.6	8.2	0.8	0.7	1.8	0.6	1.8	0.5	0.0	0.6	1.5	1.6	0.8	1.5	2.9	1.5	1.4	-0.0	0.5	-0.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.5	6.3	-0.2	-0.0	1.6	0.1	2.1	0.5	0.6	-1.3	1.8	2.5	0.7	0.3	1.1	1.4	0.1	0.7	0.3	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.7	0.8	1.0	0.4	1.1	-1.5	0.6	1.1	1.8	0.3	-0.2	-1.9	0.4	-0.5	0.1	0.1	0.0	0.5	0.8
Medication: Ibuprofen	0.7	0.8	6.2	1.4	-0.1	0.3	1.0	-0.5	-0.2	0.7	0.3	-0.4	-1.4	0.2	0.9	0.1	-1.0	0.4	0.0	0.9	2.5
Pulse rate, automated reading	0.7	2.1	7.9	-2.8	-1.5	-0.4	-1.1	-1.3	-1.2	1.0	-1.4	-2.2	-1.7	-1.3	-1.5	-1.5	-1.0	0.9	-1.4	-1.1	-1.0
Alcohol intake frequency.	0.7	1.6	6.4	-0.4	-1.5	0.9	-2.5	1.1	0.9	-0.4	-2.0	0.4	1.3	1.4	0.8	0.7	-0.7	1.1	1.2	0.3	-2.1
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.6	0.9	-0.0	1.6	1.2	-0.5	1.2	0.7	1.6	1.0	-0.1	1.5	0.5	1.3	-0.2	-0.6	0.2	0.7	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.2	-0.9	-1.0	-1.4	-1.4	1.1	-1.3	0.5	-1.8	-1.4	0.3	-1.3	-0.6	-0.4	-0.3	-1.3	-0.3	-0.9	-1.0
Average weekly champagne plus white wine intake	0.7	1.0	5.0	0.0	0.2	-0.7	0.7	-1.9	-0.1	1.8	0.0	-1.2	-1.0	-2.2	-0.4	-0.8	-0.6	-0.9	-0.9	-0.2	0.3
Eye problems/disorders: Glaucoma	0.7	0.9	2.9	0.3	0.0	1.6	-0.1	0.9	0.9	-1.2	-1.2	-1.2	0.9	-0.3	0.0	-0.5	-0.1	-1.7	1.6	0.7	0.2
Ever smoked	0.7	1.2	3.6	-1.9	1.3	-0.2	-0.5	0.4	-0.9	1.2	0.4	0.6	1.1	-1.8	-1.0	0.5	1.2	-1.6	-0.3	-1.3	-1.1
Pain experienced in last month	0.7	1.2	3.5	1.6	0.5	1.7	0.4	-0.3	1.4	0.5	1.2	1.9	1.3	1.4	0.9	0.1	1.4	0.8	1.1	1.0	0.5
Alzheimer’s Disease (in mother)	0.6	0.8	3.4	-0.9	-0.7	1.8	-1.7	0.4	0.8	-0.6	0.1	0.6	-0.1	-0.4	-0.4	-1.0	-0.2	-1.6	-0.3	-0.7	0.6
HDL Cholesterol	0.6	1.0	3.0	1.5	-1.1	1.7	1.4	-0.1	0.5	-0.4	1.2	-1.2	0.2	0.6	0.6	0.7	-0.5	0.8	1.5	1.1	0.5
Rheumatoid Arthritis	0.6	0.9	2.2	0.5	-1.3	1.1	-1.4	-1.1	-0.8	1.0	-1.1	0.2	-0.8	1.4	-0.2	-0.9	-1.5	-0.5	-0.2	0.2	-0.1
Respiratory disease	0.6	1.3	4.2	0.4	-1.5	-1.4	-1.0	0.1	0.5	0.0	-2.0	-1.9	0.4	1.1	0.9	-1.1	-0.4	0.5	1.3	1.9	0.0
Medication: Metformin	0.6	0.8	4.4	-0.2	-2.0	-1.0	0.0	-0.8	-0.3	2.1	-0.6	-1.6	-0.4	-0.2	-0.4	-1.0	-0.6	-0.6	0.0	0.1	-0.3
Impedance of leg (right)	0.6	2.8	7.3	1.6	1.8	1.1	1.6	1.3	1.2	0.5	2.3	2.3	2.7	0.1	2.0	2.1	2.5	0.9	1.7	1.4	0.5
Tinnitus: Yes, but not now, but have in the past	0.6	0.7	1.7	-1.0	-1.2	0.5	-0.8	-0.4	-0.2	0.1	-1.3	-1.0	-0.9	1.0	-1.0	-0.5	-1.3	0.6	0.3	-0.8	0.4
Multivitamins +/- minerals	0.6	0.7	3.7	0.1	0.1	1.7	0.7	-0.9	-0.7	-0.8	1.9	0.4	-0.5	-0.7	0.6	-0.2	-0.1	1.4	-0.1	0.3	1.1
Illnesses of siblings	0.6	0.8	3.0	0.2	1.2	1.7	0.7	0.5	0.6	1.1	1.5	1.2	-0.1	0.9	-0.5	0.7	1.1	-0.2	-0.1	-0.8	-0.2
Number of live births	0.6	0.8	4.6	-0.0	-0.7	-1.0	0.2	1.0	-0.2	-2.1	-0.9	0.7	1.3	0.7	1.1	0.5	0.6	-0.5	1.1	0.6	-0.3
Birth weight of first child	0.6	1.0	3.3	-1.1	0.9	-0.4	0.5	-0.9	-1.7	-1.1	1.2	0.7	-1.1	-0.7	-1.3	0.5	-0.2	0.1	-1.5	-1.8	-0.3
Medication: Ventolin 100micrograms inhaler	0.6	0.8	6.3	0.1	0.5	0.1	0.1	-0.3	0.8	2.5	0.1	0.3	-0.4	0.5	0.7	-1.1	-0.1	1.4	0.4	0.9	1.0
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.5	-0.3	-0.1	0.7	-1.3	1.0	-0.1	0.6	-1.3	1.6	0.5	0.8	0.4	-1.5	0.3	0.2	0.6	0.2	0.0
Medication for cholesterol	0.6	0.9	2.9	1.1	0.9	0.6	0.6	1.7	-0.3	0.7	0.7	1.6	0.7	0.1	0.7	1.5	1.0	0.1	-0.3	0.1	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.3	-1.0	-1.5	-0.7	-1.1	-1.5	-1.2	0.6	-0.8	-0.5	-0.6	-0.0	-0.2	-0.2	-0.9	0.7	-0.9	-0.9	0.0
Back pain experienced in last month	0.6	0.8	5.4	-0.9	-0.7	-0.7	-0.4	0.3	-1.7	-2.3	-0.6	-0.8	-0.2	-0.2	-0.3	-0.8	-0.9	-1.3	-0.2	-0.2	-0.0
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.3	-1.3	-0.1	-1.5	-0.8	0.2	-1.4	-1.8	-0.3	-0.4	-0.5	-0.9	-0.3	-0.9	-0.5	0.9	-0.8	-0.6	-0.6
Age started oral contraceptive pill	0.6	0.8	5.5	0.7	-0.3	-1.3	2.3	-0.6	0.4	1.2	1.5	-1.2	-0.5	-0.1	-0.6	0.4	-0.0	0.5	-0.4	-0.1	-0.3
Bipolar Disorder or Schizophrenia	0.5	1.3	5.4	0.8	1.1	0.2	1.0	-1.4	-0.9	-0.8	2.3	1.1	-0.3	1.4	1.3	0.8	-0.4	1.9	0.2	0.5	1.4
Schizophrenia (2018)	0.5	1.0	5.4	0.9	0.9	0.3	1.3	-0.7	-0.2	-0.8	2.3	0.9	-0.1	1.8	0.9	1.1	-0.4	1.3	0.4	0.5	0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	4.0	-0.5	-0.8	0.1	-1.4	-0.9	0.6	-0.5	0.4	-0.3	-0.4	-0.7	-0.2	-1.5	-0.4	-0.6	0.8	0.1	2.0
Breast Cancer	0.5	1.3	6.2	-1.4	-0.7	-1.1	-2.5	0.8	0.8	0.3	-2.3	0.2	1.8	0.0	0.7	-1.1	0.6	1.0	0.7	-0.2	-0.8
Coronary Artery Disease (CAD)	0.5	0.6	2.3	-0.5	-0.9	1.0	-0.9	-0.0	-0.7	0.9	0.7	0.5	-0.9	-0.2	0.0	0.0	-0.2	1.5	-0.6	-0.6	1.3
Neuroticism	0.5	1.3	4.2	-0.6	-1.7	-0.8	-2.0	-1.4	0.3	1.4	-1.1	-1.5	-1.4	-0.1	-0.4	-1.4	-1.9	-0.0	-0.4	-0.4	0.1
Hand grip strength (left)	0.5	1.2	5.3	-1.7	0.4	-0.3	-0.3	-0.2	-0.9	0.4	-0.7	0.9	-0.4	0.0	-1.5	0.6	0.7	-0.3	-2.0	-2.0	-2.3
Vitamin and mineral supplements	0.5	0.7	2.9	0.1	0.4	-1.7	-1.1	0.9	0.9	0.5	-1.7	0.1	0.7	0.5	-0.4	-0.2	0.5	-1.4	-0.2	-0.3	-1.1
Diabetes (father)	0.5	0.7	2.1	-0.1	-1.0	-1.4	-0.2	-1.2	0.4	-1.4	0.3	-0.1	-0.6	0.8	0.7	-1.0	-0.9	1.0	0.5	0.7	0.4
Fed-up feelings	0.5	0.9	5.1	-0.9	-1.5	0.4	-2.2	0.6	-0.7	-0.5	-2.0	-0.4	0.5	-0.6	0.1	-0.7	-0.9	0.2	0.4	-0.3	-0.0
Qualifications: CSEs or equivalent	0.5	0.6	4.1	0.3	-0.9	1.3	-1.0	0.2	2.0	0.4	0.1	-0.3	0.3	1.2	0.5	-0.4	-0.1	-0.2	0.5	0.8	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	2.6	-1.1	-1.2	-0.1	-0.4	0.3	-1.6	-0.5	-1.6	-1.5	-1.1	-0.8	-1.4	0.0	-0.9	-0.5	-1.3	-1.1	-0.6
Financial difficulties in last 2 years	0.5	0.7	3.3	-1.2	-0.7	-0.1	-0.6	-0.7	-0.7	-1.8	0.2	0.1	-0.8	1.2	-0.5	-0.9	-0.6	0.3	-0.1	-0.6	0.9
Mouth/teeth dental problems	0.5	0.8	2.5	0.1	1.0	1.5	1.5	-1.3	0.6	1.4	1.6	0.3	-1.0	0.0	-0.8	0.3	0.2	0.0	-0.7	-0.2	0.4
Medication: Simvastatin	0.5	0.7	4.5	-0.0	0.7	-2.1	0.1	-1.2	-0.1	-1.1	0.4	-0.2	0.7	-0.6	0.5	-0.2	0.9	0.5	1.2	1.0	-0.8
Neuroticism score	0.5	1.1	4.0	-0.2	-1.3	0.1	-2.0	-1.7	0.7	1.5	-1.0	-1.2	-1.0	-0.2	0.1	-0.5	-1.7	0.6	-0.3	-0.3	0.5
Falls in the last year	0.5	0.6	2.2	0.9	-0.8	-0.8	-0.6	0.4	1.0	-0.5	-0.6	-0.1	0.1	0.7	1.5	0.7	-0.6	1.1	0.7	1.1	-1.0
Happiness	0.5	0.6	2.8	0.8	0.4	0.5	1.6	-0.1	-1.2	-0.3	1.1	0.2	0.1	-1.0	0.2	1.7	0.1	-0.1	-0.8	-0.3	0.3
Noisy workplace	0.5	0.6	3.1	-1.2	-1.1	0.1	-1.0	-0.3	1.0	0.3	-1.8	-0.2	0.3	-0.4	-0.6	-0.3	-0.4	-0.1	0.1	-0.4	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	3.7	0.6	-0.4	-0.0	0.3	-0.6	-0.5	1.4	-0.2	-0.8	-1.3	-0.0	0.6	-0.2	-1.3	0.8	-0.1	0.6	1.9
Pulse wave reflection index	0.5	0.6	2.3	1.1	0.3	-1.4	-0.5	-0.7	1.1	-0.0	-0.6	-0.3	0.4	0.4	0.6	-0.4	-0.5	-1.0	1.5	1.0	0.5
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.7	1.7	-0.2	0.3	1.2	-0.1	0.9	-0.1	-0.5	0.4	-0.2	1.0	1.1	1.2	0.0	0.6	0.4	0.9	-0.2
Loud music exposure frequency	0.5	0.6	4.1	0.4	-1.1	0.1	-0.0	0.8	-0.6	2.0	-1.1	0.1	-0.1	-0.0	0.2	0.3	-0.3	0.6	-0.3	0.1	1.2
Glaucoma (self-reported)	0.5	0.6	2.6	0.5	0.1	1.6	0.6	0.6	0.1	-1.4	-0.8	-1.2	-0.1	-0.0	-0.1	-0.1	-0.4	-1.1	0.7	0.3	0.9
Forced vital capacity (FVC), Best measure	0.5	1.9	6.7	1.1	0.9	0.8	0.4	1.4	1.4	-0.1	-0.0	1.8	2.2	0.9	2.0	1.7	1.6	2.6	0.7	0.9	-0.3
Mouth/teeth dental problems: Loose teeth	0.5	0.6	2.4	0.2	1.3	-0.9	0.6	1.0	-1.0	-1.6	0.2	1.0	0.1	0.0	1.5	-0.2	0.5	0.3	-0.3	0.0	0.2
Emphysema/chronic bronchitis	0.5	0.6	2.7	-0.4	1.6	-0.3	-0.8	0.2	-0.2	-0.3	-0.5	0.6	0.7	-1.1	0.1	-0.4	1.5	-1.0	-0.6	-0.5	0.2
Chest pain or discomfort	0.5	0.7	5.1	-0.9	0.0	-2.2	0.4	0.7	-0.3	-0.8	-0.4	-1.2	0.2	-0.6	0.7	-0.5	0.4	-1.5	0.0	0.0	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.8	1.4	1.3	1.7	1.2	0.9	-0.2	1.1	1.5	1.0	0.2	-0.1	1.5	1.3	0.6	0.8	-0.2	0.5	1.1
Diabetes diagnosed by doctor	0.5	0.8	2.9	-0.5	-1.4	-1.2	-0.8	-0.9	0.1	-0.5	-0.7	-1.0	-0.2	0.5	-0.6	-1.7	-0.2	-1.6	0.2	0.0	-1.2
Friendships satisfaction	0.5	0.6	3.8	0.1	-0.4	-0.6	0.7	-2.0	0.8	0.5	0.3	-0.3	-1.0	-0.7	-0.6	0.0	-0.9	-1.6	-0.4	-0.3	-0.3
Medication: Atorvastatin	0.5	0.7	1.8	-0.7	-1.2	-0.9	-1.3	-0.6	1.0	0.3	-0.9	-1.0	0.2	-0.7	-0.2	-1.1	-0.9	0.0	0.3	-0.0	-1.2
Bipolar Disorder (2018)	0.4	0.6	2.5	0.1	0.7	-0.1	0.2	-1.3	-1.2	-0.4	0.9	0.7	-0.4	-0.1	1.0	-0.1	-0.3	1.6	-0.1	0.3	1.3
LDL Cholesterol	0.4	0.6	2.0	-1.2	-0.7	0.4	0.1	0.0	-0.7	-0.4	0.4	-0.7	-1.4	0.4	-0.6	-1.3	-0.2	-1.0	-0.8	-0.5	0.6
Systolic Blood Pressure	0.4	2.0	6.7	-1.8	-0.0	0.1	-1.0	-0.4	-1.0	-1.0	-1.4	-1.7	-2.6	-0.8	-2.2	-1.9	-1.4	-1.3	-1.5	-1.5	0.2
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.8	-1.4	-0.4	-0.8	0.2	0.2	-1.1	-1.1	-1.3	-0.1	0.2	-0.3	-0.6	-0.3	0.2	0.3	-0.8	-1.1	-0.3
Hand grip strength (right)	0.4	1.1	3.3	-1.5	0.0	0.1	-0.8	0.3	-0.7	1.3	-1.2	0.8	-0.3	-0.5	-1.6	-0.5	0.7	-0.3	-1.6	-1.8	-1.8
Townsend deprivation index at recruitment	0.4	0.6	1.7	0.7	1.3	0.5	0.5	1.2	-0.1	-0.7	0.4	1.1	1.0	0.9	0.8	0.8	0.8	0.2	0.5	0.6	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.6	-0.8	-0.9	0.6	-0.7	0.2	-0.4	-0.9	-0.4	0.5	-0.7	1.2	-0.1	-0.5	-0.8	-0.7	-1.0	-0.8	-0.6
Relative age voice broke	0.4	0.7	1.8	1.0	0.4	0.5	0.9	-0.8	0.3	-1.2	0.8	0.4	-0.2	1.3	1.1	0.7	-0.1	-0.5	0.9	0.8	1.3
Age when periods started (menarche)	0.4	1.0	3.9	-0.4	1.3	0.3	1.4	1.9	0.5	0.5	-0.1	1.3	1.2	0.4	0.4	0.6	2.0	-0.6	0.4	-0.0	-1.4
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.6	1.3	0.5	0.8	0.6	1.0	-0.5	0.2	0.7	-0.1	-0.6	0.2	1.2	0.9	-0.3	0.5	0.2	0.6	0.8
Allergy	0.4	1.0	3.3	-1.2	-0.2	-1.0	-0.8	-0.3	1.8	-0.2	-0.4	1.7	0.9	0.7	-0.8	-0.8	0.5	-0.6	0.6	-1.1	-1.7
Medication: Ramipril	0.4	0.5	2.1	-0.7	0.7	-0.9	-0.0	0.2	-1.4	0.4	0.5	0.3	0.2	0.1	0.1	0.4	0.7	1.1	-1.4	-1.1	0.6
Worrier / anxious feelings	0.4	0.8	4.0	0.3	-0.2	-0.9	0.1	-1.0	-0.3	1.3	0.6	-1.3	-0.6	-1.3	1.2	0.6	-0.4	2.0	-0.4	-0.1	0.6
Depression (self-reported)	0.4	0.5	1.4	0.1	1.0	-0.6	0.3	0.8	0.2	1.0	-0.8	0.7	1.0	0.1	-0.0	0.8	1.2	0.8	-0.4	-0.3	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	4.8	0.8	0.7	1.4	0.1	0.9	1.3	0.2	0.4	1.6	1.3	0.5	1.5	1.3	1.1	2.2	0.2	0.3	0.3
Pulse wave Arterial Stiffness index	0.4	0.5	4.1	-0.5	-0.6	-2.0	-0.7	-0.9	-0.1	0.7	-0.5	-0.1	0.1	-0.8	-0.0	-0.0	-0.6	-0.6	0.2	-0.3	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.0	0.7	0.3	0.3	-1.2	-0.1	1.2	-0.6	-0.1	0.6	0.9	0.4	1.4	-0.9	0.3	-0.0	0.9	1.0	0.3
Hair/balding pattern: Pattern 4	0.4	0.9	2.6	0.7	-1.1	-1.6	-0.2	-0.5	1.4	-1.0	-1.3	-1.6	0.0	0.5	-0.2	0.6	-1.1	-0.5	0.9	0.6	-1.2
Birth weight	0.4	0.9	4.4	-0.3	0.3	-0.6	-0.9	-2.1	-0.5	-0.7	-0.0	0.6	-0.8	-0.0	-1.6	-0.6	-0.4	0.3	-0.5	-0.8	-2.0
Pulse wave peak to peak time	0.4	0.5	4.0	0.3	0.8	2.0	0.9	0.9	0.2	-0.6	0.4	0.4	0.1	0.8	-0.0	-0.1	0.9	0.7	-0.2	0.2	0.4
Migraine (self-reported)	0.4	0.5	1.3	-0.5	0.1	-0.9	-0.4	1.1	-0.7	-0.3	-1.1	0.7	1.1	-0.8	0.2	-0.1	0.8	0.8	0.3	-0.3	-0.8
Suffer from ‘nerves’	0.4	0.6	3.3	-0.5	-0.8	0.6	-1.1	-0.1	0.1	1.8	-1.4	-0.2	-1.0	0.2	-0.4	-0.4	-0.7	-0.4	-0.9	-0.6	0.3
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.3	0.1	-0.2	1.0	-0.3	-0.3	0.2	-1.1	-1.1	0.4	-0.0	0.8	-0.8	1.1	0.5	-0.3	-0.9	-0.5	-0.6
Average weekly red wine intake	0.4	0.5	2.0	1.2	0.6	-0.5	1.0	-1.0	-0.7	-0.4	0.3	-0.4	-0.3	-0.3	0.7	0.8	0.5	0.8	0.2	0.8	1.4
Commuting to job workplace: Walk	0.4	0.4	1.6	0.2	0.3	-0.1	0.6	-0.6	0.2	-1.1	-0.3	0.2	-0.4	1.1	0.1	-0.7	-0.1	-1.2	0.1	-0.1	1.1
Miserableness	0.4	0.6	1.5	0.7	-0.6	1.0	-1.1	0.9	1.0	0.4	-1.1	0.1	0.4	1.2	1.0	0.2	-0.4	-0.4	1.0	0.9	0.7
Financial situation satisfaction	0.4	0.5	2.8	-0.9	-0.7	-0.0	0.3	-0.3	0.9	0.8	-0.8	-0.2	-1.1	1.7	-0.1	-0.3	-1.2	0.3	-0.2	-0.1	0.3
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.9	0.3	-0.7	-0.4	-0.1	0.1	0.2	0.3	-1.0	0.4	-0.0	1.7	0.2	0.5	0.5	1.0	-0.9	0.2	-0.7
Irritability	0.4	0.7	5.0	-0.2	-0.1	-0.6	-0.2	-1.7	-0.1	1.0	1.0	0.2	-0.6	-1.2	0.3	0.3	-0.1	2.2	-0.9	-0.5	-0.1
Risk taking	0.4	0.6	5.3	0.6	-0.7	1.1	-0.0	-0.5	-0.5	0.7	1.0	-0.9	-0.5	0.1	0.2	0.2	-0.3	0.3	0.1	0.2	2.3
Depressed Affect (Nagel 2018)	0.3	0.7	2.6	-1.4	-0.7	-0.5	-1.6	-0.2	-0.9	0.1	-1.1	-0.1	-0.9	-0.6	-0.8	-0.6	-0.8	-0.2	-1.0	-1.3	0.0
Crohns Disease (2017)	0.3	0.7	2.9	-0.0	0.9	-1.3	-0.4	-1.5	0.3	0.0	1.5	-1.5	-0.5	-0.4	0.3	-0.0	-0.7	1.7	0.4	0.3	-0.1
Irritable Bowel Disease (IBD)	0.3	0.7	2.2	1.0	0.8	-0.3	-0.9	-0.6	1.2	-0.6	0.8	-1.2	0.4	0.5	1.2	-0.2	-0.3	0.5	1.5	1.4	0.5
Reaction Time	0.3	0.6	3.2	-0.5	-1.8	0.8	-0.2	-0.8	-0.3	1.1	-0.3	-0.7	-0.5	-0.4	-0.8	-0.3	-1.1	-0.2	-0.8	-1.0	0.1
Crohns Disease (2012)	0.3	0.4	2.0	0.6	0.2	-0.9	-0.2	-0.5	0.4	0.3	0.7	-1.4	-0.1	0.2	0.2	0.0	-0.5	0.8	1.2	0.9	0.5
HbA1C	0.3	0.3	1.1	-0.5	-0.4	-0.2	-0.5	-0.1	-0.3	1.1	-0.9	0.2	0.0	-0.3	0.3	-0.2	-0.2	0.9	-0.6	-0.9	0.3
Triglycerides	0.3	0.5	2.1	-1.0	0.3	-0.4	-0.3	0.6	-0.3	-1.4	-0.9	0.4	0.2	-0.3	-0.7	-1.1	0.7	-1.2	-0.3	-0.6	-0.4
Blood Eosinophil Count	0.3	2.6	9.2	1.8	-0.4	1.4	-1.6	1.1	1.3	-0.2	-0.6	-0.3	1.4	2.3	2.0	0.4	-0.9	1.5	3.0	2.9	1.8
Heel T-Score	0.3	2.6	7.6	-1.0	-2.6	-1.3	0.0	-1.1	-0.6	0.2	-2.6	-2.8	-2.2	-1.0	-2.1	-1.4	-1.8	-1.5	-1.6	-1.2	-0.1
Smoking Status	0.3	0.7	3.7	-0.6	0.6	0.1	0.2	0.1	0.1	1.4	0.9	0.4	1.1	-1.7	0.5	0.6	0.2	-1.9	0.9	0.2	-0.4
Cardiovascular Disease	0.3	1.1	4.2	-1.5	-0.5	-0.6	-1.6	-1.4	-0.4	-1.4	-0.7	-1.0	-1.1	-0.5	-1.1	-2.0	-1.0	-0.3	-0.1	-0.4	-1.0
Sensitivity / hurt feelings	0.3	0.5	1.7	-1.3	-0.3	-0.6	-1.1	-0.9	-0.8	0.3	-0.0	-0.6	-1.0	0.4	-0.1	-0.5	-0.8	-0.2	-1.0	-1.0	-0.1
Diabetes (mother)	0.3	0.4	1.7	0.1	-0.2	-0.5	0.2	-1.3	-0.5	-0.9	0.6	-0.2	-1.0	0.5	-0.3	-0.1	-0.6	-0.4	-0.2	-0.0	1.2
Average weekly fortified wine intake	0.3	0.3	1.1	1.1	-0.5	-0.4	-0.1	-0.9	-0.2	-0.6	-0.3	-0.8	-0.0	-0.6	0.6	0.6	0.0	-0.0	-0.0	0.8	0.5
Maternal smoking around birth	0.3	0.5	2.2	-0.9	-0.4	-0.4	0.7	-0.1	0.3	1.0	0.3	-0.3	-1.4	1.5	0.2	-0.4	-0.8	0.5	-0.7	-0.3	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.6	-0.5	-1.2	0.3	0.0	0.2	-1.1	-0.4	-1.0	-1.1	-1.0	-0.2	-0.8	0.6	-0.9	0.7	-1.1	-0.8	-0.4
Alcohol usually taken with meals	0.3	0.5	2.1	0.5	1.0	-0.6	0.8	-1.1	-0.8	1.5	1.0	0.4	-0.3	-0.6	0.5	0.6	0.5	-0.0	-0.7	0.3	0.5
Nervous feelings	0.3	0.6	2.4	0.0	-1.1	0.5	-0.9	-1.0	0.9	-0.5	0.2	-1.2	-0.5	0.7	-0.2	0.1	-1.6	0.3	0.8	0.4	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.4	-0.1	0.7	-0.6	0.5	0.4	-0.9	0.5	-0.2	0.4	-0.4	-0.0	-0.0	1.4	0.0	0.2	-1.6	-1.1	-0.3
Pain all over the body in last month	0.3	0.4	1.4	0.4	-1.1	-0.6	-0.4	0.1	1.2	0.4	-0.1	-0.0	0.3	0.8	0.0	0.4	-0.6	-0.5	0.8	0.3	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.2	-0.6	-0.4	-0.9	-0.3	0.1	0.1	-0.9	-0.4	-0.6	-1.1	1.1	1.1	0.3	-1.5	0.2	-0.1	-0.1	-0.4
Asthma	0.3	0.5	1.9	-0.5	-0.8	-1.4	-0.5	-0.3	0.3	1.1	-1.4	-0.8	-0.2	0.1	-0.0	-0.7	-0.4	0.8	0.4	0.6	-0.5
High blood pressure (siblings)	0.3	0.5	3.2	-0.6	-0.7	-0.7	-0.5	0.3	-0.7	-1.3	-1.8	-0.6	-0.1	-0.7	0.4	-0.1	-0.5	0.5	0.0	0.4	-0.1
Comparative body size at age 10	0.3	0.8	2.6	-0.7	-0.1	-0.4	-0.0	-0.8	-1.0	-0.3	-0.8	-0.7	-1.1	-1.0	-1.6	-1.1	-0.8	-1.3	-1.2	-0.8	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.8	-0.2	0.3	-0.7	-1.2	-0.1	0.1	-0.9	-0.3	0.8	0.2	0.3	0.2	-1.0	0.3	-0.1	-0.5	-0.5	-1.3
Age at first live birth	0.3	0.6	2.8	0.8	-0.2	-0.3	0.0	-0.5	-1.3	-0.5	0.0	-1.3	-1.7	-0.1	-0.8	-0.5	-0.9	0.3	-1.0	0.0	0.9
Neck or shoulder pain in last month	0.3	0.4	2.1	-1.0	0.4	-0.2	-1.1	0.5	-0.6	-0.6	-0.2	-0.7	-0.1	-0.1	-0.1	0.3	0.1	1.5	-0.8	-0.4	-0.1
Mean time to correctly identify matches	0.3	0.6	1.8	-1.2	-1.1	0.1	-0.7	-0.8	-0.3	1.2	-0.1	0.3	-0.0	-0.7	-0.9	-0.6	-0.5	-0.1	-0.9	-1.4	-1.2
Age at last live birth	0.3	0.5	1.7	1.3	0.2	0.7	0.4	1.1	-0.2	-1.1	0.1	-0.4	0.1	0.6	0.6	0.1	-0.0	0.4	0.8	1.1	0.9
Supplements: Vitamin C	0.3	0.3	1.7	0.3	0.0	0.5	1.3	-0.1	-0.1	0.4	0.5	0.2	-0.0	-0.3	0.3	0.6	0.2	1.1	0.6	0.6	0.7
Mood swings	0.3	0.5	1.9	-0.9	0.2	0.7	-1.4	0.4	-0.8	-0.3	-1.2	0.7	0.3	-0.8	-0.4	0.5	-0.1	-0.4	-0.5	-1.1	-0.3
Mineral and other dietary supplements	0.3	0.4	2.7	0.4	0.2	-0.1	0.4	-0.1	1.2	1.6	-0.1	0.7	0.4	0.7	0.2	0.6	0.6	0.1	0.4	0.2	-0.4
Breast cancer (self-reported)	0.3	0.4	1.4	0.4	-1.1	0.5	-0.2	-0.6	0.2	-0.1	0.5	-0.7	-0.2	-0.2	0.9	-1.2	-0.4	0.4	0.7	1.0	0.3
Asthma (self-reported)	0.3	0.6	2.4	-0.7	-1.0	-1.4	-0.9	-0.5	-0.1	1.0	-1.6	-1.0	-0.5	0.0	-0.2	-1.0	-0.5	0.5	0.0	0.3	-0.4
Number of self-reported non-cancer illnesses	0.3	0.6	3.8	-0.2	0.4	0.5	-0.4	1.9	-0.2	-0.6	-0.2	0.6	1.1	0.8	0.7	-0.1	1.1	-0.6	0.4	0.5	-0.7
Fractured/broken bones in last 5 years	0.3	0.4	1.8	-0.3	0.2	-0.9	-0.6	-1.3	-0.1	-1.3	-0.2	-0.9	-0.2	-1.0	-0.1	-0.7	-0.5	-0.1	0.3	0.0	0.5
Heart disease (siblings)	0.3	0.4	1.2	-0.8	-1.1	-0.6	-0.6	-0.3	-0.3	-0.2	-0.9	-0.1	0.3	-0.4	0.0	-1.1	-0.8	-0.9	0.4	0.1	0.7
Depression (Nagel 2018)	0.2	0.3	1.9	-0.2	-0.1	-0.2	0.1	-0.1	-0.9	-0.7	-0.2	0.2	-1.1	0.4	0.2	-0.0	-0.9	-0.1	-1.4	-0.5	0.0
Neuroticism (Nagel 2018)	0.2	0.5	1.5	-0.7	-0.7	-0.8	-0.7	-0.4	-0.5	0.8	-0.7	-1.0	-1.2	-0.1	-0.1	-0.4	-0.6	-0.1	-1.0	-0.8	0.1
Worry (Nagel 2018)	0.2	0.3	1.7	0.6	-0.3	-0.6	0.1	-0.5	0.9	1.3	-0.1	-0.9	-0.7	0.3	0.6	0.2	-0.2	0.1	-0.4	0.3	0.5
Prostate Cancer	0.2	0.3	1.1	0.2	0.9	-1.1	0.4	-0.9	-0.4	0.5	0.0	-0.0	0.1	0.5	0.0	-0.3	0.3	0.2	-0.6	-0.5	0.6
Blood Red Count	0.2	1.6	4.5	-2.0	-0.5	1.8	-0.1	0.1	-0.7	-2.0	-1.2	-0.8	-1.0	1.3	-2.1	-0.3	-1.0	-0.4	-0.8	-1.3	-2.0
Waist Hip Ratio (WHR)	0.2	0.8	2.7	0.6	0.7	-0.4	0.1	-0.0	0.7	0.1	1.3	0.9	1.3	0.9	1.5	0.5	0.9	1.0	1.6	1.3	0.0
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.4	-0.3	0.2	-0.2	-0.3	-0.1	-0.8	-1.2	-0.3	0.3	-0.5	0.3	0.4	0.0	-0.8	0.3	-0.5	-0.2	0.1
Supplements: Glucosamine	0.2	0.3	0.8	0.4	0.8	-0.2	0.5	0.9	-0.6	-0.9	0.1	0.8	0.5	0.4	0.5	-0.2	0.8	-0.6	-0.6	0.2	-0.2
Tense / ‘highly strung’	0.2	0.3	1.3	0.2	0.1	-0.1	-0.8	-0.5	0.4	0.3	-0.9	0.5	0.0	-0.0	1.0	0.6	-0.1	1.1	-0.3	-0.2	0.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.9	-0.6	0.9	-0.2	-0.2	0.2	-0.3	-0.1	-0.1	0.3	0.4	-0.4	-0.1	0.3	0.3	0.5	-0.6	-1.0	-0.7
Family relationship satisfaction	0.2	0.2	1.2	0.3	0.5	0.1	1.1	-0.4	-0.2	-0.8	0.5	0.3	-0.0	-0.8	0.3	0.5	-0.3	-0.6	0.3	0.3	0.2
Loneliness, isolation	0.2	0.2	1.3	0.2	-0.2	0.3	-0.1	0.3	-0.2	0.5	0.4	-0.4	-1.2	-0.5	-0.0	-0.1	-0.6	-0.1	-0.8	-0.1	0.4
Average weekly beer plus cider intake	0.2	0.3	2.4	0.3	-0.4	1.6	-0.6	-0.7	0.5	0.9	0.6	0.5	-0.5	0.2	0.1	-0.2	-0.7	0.1	-0.2	0.0	0.3
Blood Platelet Count	0.1	1.0	4.8	-1.0	-0.4	-0.0	-1.2	0.5	-0.4	-2.2	-1.3	-1.1	0.3	0.3	-0.1	-1.5	-0.6	0.7	1.1	0.6	-1.5
Blood White Count	0.1	0.9	3.4	-0.9	-0.4	-1.0	-1.6	0.2	-1.0	-1.8	-1.1	-1.0	0.4	0.1	0.4	-1.6	-0.6	-0.3	1.1	0.2	-0.8
Hair Pigment	0.1	1.8	6.2	-2.1	-2.5	0.1	-1.8	-0.4	-0.7	0.2	-1.8	-1.1	-0.2	0.2	-1.8	-1.5	-1.9	-0.3	-1.4	-1.7	-0.1
Tanning	0.1	1.5	5.4	1.3	-1.0	1.2	-0.1	-0.9	2.3	-0.6	1.1	0.8	0.3	1.7	1.2	0.2	-0.9	0.2	2.1	2.2	0.7
Sitting height	0.1	0.6	1.8	-0.7	-0.4	0.3	0.3	-1.3	-0.3	0.4	-0.2	-0.9	-1.3	0.8	-0.8	-1.0	-0.9	1.1	-0.8	-0.7	0.1
Time employed in main current job	0.1	0.1	0.5	-0.2	0.6	-0.4	-0.7	-0.3	0.1	-0.2	0.2	0.4	0.1	-0.1	-0.1	-0.4	0.2	0.3	0.5	0.2	-0.6
Standing height	0.1	1.1	5.4	-0.9	0.3	-0.7	0.9	-2.3	-1.3	-0.4	0.9	-0.0	-1.2	-1.2	-1.3	-0.7	-0.6	1.2	-0.9	-1.3	-0.4
Worry too long after embarrassment	0.1	0.2	1.0	-0.4	-0.1	-0.6	-0.2	-0.2	-0.1	-0.0	-0.9	-0.8	-0.5	0.1	-0.0	-1.0	-0.5	-0.6	-0.5	-0.2	-0.1
Comparative height size at age 10	0.1	0.4	1.5	0.0	0.7	0.5	0.5	-0.5	-0.4	-0.2	0.4	1.2	0.6	-1.0	-0.9	0.5	-0.0	1.0	0.6	-0.4	-0.8
Height	0.0	0.7	3.9	-0.8	-1.1	-0.0	0.4	-2.0	-0.3	0.6	0.2	0.4	-0.7	-0.3	-1.4	0.1	-0.7	1.3	-0.6	-1.0	-0.8

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