Best TWAS P=2.34e-09 · Best GWAS P=1.69e-11 conditioned to 3.77e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | INADL | 0.15 | 0.06 | lasso | 5 | 0.05 | 1.7e-04 | 5.4 | -5.5 | 4.9e-08 | 0.81 | 0.07 | 0.44 | FALSE |
| 2 | GTEx | Esophagus Muscularis | TM2D1 | 0.12 | 0.03 | lasso | 3 | 0.04 | 3.2e-03 | 4.5 | 6.0 | 2.3e-09 | -0.55 | 0.02 | 0.86 | TRUE |
| 3 | METSIM | Adipose | L1TD1 | 0.17 | 0.07 | enet | 23 | 0.10 | 2.7e-15 | -3.9 | -5.2 | 2.6e-07 | 0.11 | 1.00 | 0.00 | FALSE |