Best TWAS P=1.8e-15 · Best GWAS P=7.24e-18 conditioned to 0.000115
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 7.8 | -8.0 | 1.8e-15 | -0.85 | 0.16 | 0.82 | TRUE |
2 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 6.1 | -5.9 | 3.9e-09 | 0.03 | 0.01 | 0.99 | TRUE |