Best TWAS P=3.69e-17 · Best GWAS P=2.07e-25 conditioned to 3.81e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -6.0 | 6.7 | 2.4e-11 | -0.66 | 0.73 | 0.1 | FALSE |
2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 5.5 | 8.4 | 3.7e-17 | -0.48 | 1.00 | 0.0 | TRUE |