[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr6:160,071,844-161,571,560

Best TWAS P=2.24e-14 · Best GWAS P=8.25e-18 conditioned to 6.75e-06

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Caudate basal ganglia	SLC22A3	0.15	0.10	enet	39	0.11	5.6e-04	-7.2	-7.6	2.2e-14	-0.71	0.07	0.83	TRUE
5	GTEx	Esophagus Mucosa	SLC22A3	0.19	0.08	enet	47	0.12	1.7e-08	6.1	-6.9	5.1e-12	-0.58	0.47	0.53	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	SLC22A3	0.15	0.05	lasso	9	0.05	9.9e-04	-4.0	-6.6	5.4e-11	-0.65	0.04	0.95	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	SLC22A3	0.14	0.20	lasso	10	0.19	2.4e-24	-6.1	-6.5	1.1e-10	-0.67	1.00	0.00	FALSE
6	GTEx	Nerve Tibial	SLC22A3	0.20	0.10	lasso	7	0.13	3.2e-09	-6.0	-6.4	2.0e-10	-0.56	0.99	0.00	FALSE
3	GTEx	Brain Frontal Cortex BA9	SLC22A3	0.26	0.08	lasso	6	0.05	1.5e-02	-4.4	-6.3	3.2e-10	-0.63	0.13	0.64	FALSE
1	GTEx	Adipose Visceral Omentum	SLC22A3	0.13	0.06	enet	7	0.09	1.3e-05	-6.1	-6.2	5.0e-10	-0.63	0.62	0.36	FALSE
12	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LPAL2	0.07	0.00	blup	74	0.04	1.1e-03	-3.7	6.0	2.6e-09	0.75	0.05	0.49	FALSE
10	GTEx	Testis	SLC22A3	0.19	0.01	lasso	14	0.05	2.6e-03	-8.5	-5.9	3.0e-09	-0.66	0.04	0.95	FALSE
7	GTEx	Ovary	SLC22A3	0.33	0.29	lasso	6	0.23	2.8e-06	-5.7	-5.9	4.3e-09	-0.65	0.17	0.71	FALSE
9	GTEx	Skin Sun Exposed Lower leg	SLC22A3	0.29	0.14	lasso	10	0.20	3.7e-16	3.7	-5.7	1.5e-08	-0.48	1.00	0.00	FALSE
4	GTEx	Colon Transverse	SLC22A3	0.18	0.00	enet	11	0.00	5.2e-01	4.4	-5.4	6.0e-08	-0.40	0.08	0.44	FALSE