Best TWAS P=9.02e-11 · Best GWAS P=6.11e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TEX10 | 0.18 | 0.10 | lasso | 7 | 0.12 | 2.2e-14 | -4.0 | 5.2 | 2.5e-07 | 0.65 | 0.82 | 0.18 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | TEX10 | 0.10 | 0.09 | lasso | 4 | 0.10 | 3.1e-06 | 4.0 | 5.3 | 9.5e-08 | 0.92 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | INVS | 0.19 | 0.06 | enet | 30 | 0.11 | 1.5e-09 | 5.4 | 5.2 | 2.5e-07 | 0.79 | 0.02 | 0.98 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | TEX10 | 0.27 | 0.27 | lasso | 8 | 0.28 | 7.0e-23 | 6.5 | 6.5 | 9.0e-11 | 1.00 | 0.01 | 0.99 | TRUE |
| 5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | INVS | 0.10 | 0.03 | blup | 107 | 0.07 | 4.0e-04 | 6.3 | 5.3 | 1.0e-07 | 0.89 | 0.01 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | INVS | 0.16 | 0.12 | enet | 8 | 0.08 | 2.8e-04 | 5.5 | 5.6 | 2.6e-08 | 0.77 | 0.25 | 0.64 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | INVS | 0.09 | 0.04 | enet | 14 | 0.06 | 1.5e-06 | 5.0 | 5.1 | 3.0e-07 | 0.75 | 0.04 | 0.94 | FALSE |