[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr9:126,844,856-128,824,378

Best TWAS P=9.61e-13 · Best GWAS P=1.27e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	-7.0	-7.1	9.6e-13	0.99	0.02	0.98	TRUE
3	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	-6.7	-7.1	1.2e-12	0.96	0.02	0.98	FALSE
14	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	-7.1	7.1	1.6e-12	-0.99	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	-7.0	7.0	2.1e-12	-0.95	0.02	0.90	FALSE
15	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	5.0	-6.5	9.9e-11	0.83	0.15	0.85	FALSE
12	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	5.1	6.4	1.6e-10	-0.47	0.08	0.24	FALSE
5	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	-7.1	6.2	6.1e-10	-0.82	0.05	0.80	FALSE
7	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	5.3	-5.7	1.5e-08	0.69	0.08	0.80	FALSE
11	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	5.3	5.6	1.6e-08	-0.61	0.52	0.40	FALSE
17	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	5.3	-5.6	1.9e-08	0.74	0.21	0.68	FALSE
10	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	5.0	-5.6	2.6e-08	0.62	0.98	0.02	FALSE
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	5.5	-5.5	3.8e-08	0.70	0.96	0.02	FALSE
2	GTEx	Artery Aorta	PRPS1P2	0.08	0.10	lasso	4	0.08	2.1e-05	-4.5	5.5	4.1e-08	-0.82	0.06	0.89	FALSE
9	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	5.5	5.5	4.7e-08	-0.63	0.64	0.04	FALSE
21	YFS	Blood	RABEPK	0.12	0.21	bslmm	317	0.22	2.4e-71	5.4	-5.5	4.8e-08	0.60	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	5.4	-5.4	5.3e-08	0.63	0.02	0.69	FALSE
19	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	5.3	5.4	5.9e-08	-0.67	0.92	0.08	FALSE
16	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	5.3	5.4	6.3e-08	-0.61	0.89	0.08	FALSE
20	GTEx	Whole Blood	PPP6C	0.03	0.00	enet	20	0.00	1.0e-01	-6.6	-5.4	7.1e-08	0.66	0.03	0.88	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WDR38	0.04	0.01	blup	32	0.02	9.5e-04	-2.1	-5.4	7.5e-08	0.31	0.00	0.07	FALSE
8	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	5.4	5.3	9.6e-08	-0.59	0.96	0.04	FALSE
4	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	5.3	5.3	1.1e-07	-0.60	0.88	0.09	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	5.3	-5.3	1.1e-07	0.62	0.03	0.97	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	5.3	-5.3	1.1e-07	0.61	0.03	0.96	FALSE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP6C	0.05	0.04	blup	46	0.03	3.8e-03	5.3	-5.3	1.1e-07	0.63	0.02	0.96	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	5.3	-5.2	1.6e-07	0.63	0.02	0.97	FALSE
6	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	5.3	-5.2	1.7e-07	0.59	0.07	0.10	FALSE
13	GTEx	Muscle Skeletal	PPP6C	0.03	0.03	enet	6	0.01	3.0e-02	5.2	-5.1	2.7e-07	0.62	0.49	0.12	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP6C	0.06	0.08	lasso	7	0.07	1.8e-07	5.3	-5.1	2.7e-07	0.59	0.02	0.98	FALSE