TWAS
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Traits
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Traits
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Leg fat-free mass (right)
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chr10:95,606,207-97,055,832
Best TWAS P=5.11e-08 · Best GWAS P=7.84e-13 conditioned to 6.44e-08
95.6M
95.8M
96M
96.2M
96.4M
96.6M
96.8M
97M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
HELLS
0.04
0.04
enet
12
0.04
5.1e-06
4.5
5.5
5.1e-08
0.41
0.97
0.01
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
TBC1D12
0.04
0.04
blup
63
0.03
3.9e-04
4.5
5.2
2.6e-07
0.49
0.02
0.90
FALSE