TWAS hub - HELLS

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0410	0.0180	1.5e-04	0.038	0.034	0.043	0.033	0.035	2.0e-05	4.4e-05	5.1e-06	5.5e-05	4.1e-05
2	GTEx	Adipose Subcutaneous	0.0800	0.0340	6.2e-05	0.063	NA	0.035	NA	0.032	7.7e-06	NA	7.0e-04	NA	1.1e-03
3	GTEx	Brain Cerebellum	0.2570	0.0770	1.2e-06	0.199	NA	0.157	NA	0.190	1.5e-06	NA	2.2e-05	NA	2.8e-06
4	GTEx	Brain Frontal Cortex BA9	0.1585	0.0641	8.3e-04	0.087	NA	0.148	NA	0.142	2.6e-03	NA	1.0e-04	NA	1.4e-04
5	GTEx	Nerve Tibial	0.1233	0.0391	5.4e-08	0.120	NA	0.099	NA	0.040	8.0e-09	NA	1.6e-07	NA	7.6e-04
6	GTEx	Ovary	0.1500	0.0820	7.9e-03	0.044	NA	0.052	NA	0.091	3.1e-02	NA	2.1e-02	NA	3.1e-03
7	GTEx	Skin Sun Exposed Lower leg	0.0540	0.0270	2.5e-03	0.017	NA	0.001	NA	0.005	1.4e-02	NA	2.7e-01	NA	1.1e-01
8	GTEx	Testis	0.0800	0.0390	4.3e-03	-0.001	NA	0.000	NA	-0.006	3.7e-01	NA	3.1e-01	NA	7.7e-01
9	GTEx	Thyroid	0.0740	0.0460	8.0e-03	0.001	NA	0.001	NA	0.000	2.4e-01	NA	2.7e-01	NA	2.9e-01
10	METSIM	Adipose	0.0313	0.0137	9.6e-05	0.036	0.018	0.013	0.018	0.025	3.9e-06	7.8e-04	3.9e-03	8.0e-04	9.3e-05
11	ROSMAP	Brain Pre-frontal Cortex	0.0243	0.0119	2.2e-03	0.007	0.005	-0.001	0.004	-0.002	4.0e-02	6.9e-02	5.5e-01	7.7e-02	8.2e-01
12	TCGA	Breast Invasive Carcinoma	0.0370	0.0282	6.2e-06	0.015	0.029	0.028	NA	0.020	4.0e-04	1.3e-06	1.9e-06	NA	4.3e-05
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0272	0.0162	1.3e-04	0.027	0.031	0.021	NA	0.026	4.9e-04	1.7e-04	1.6e-03	NA	6.0e-04
14	TCGA	Brain Lower Grade Glioma	0.0338	0.0239	3.4e-04	0.029	0.015	0.013	NA	0.016	2.4e-04	6.8e-03	1.2e-02	NA	5.7e-03
15	TCGA	Prostate Adenocarcinoma	0.0310	0.0198	1.8e-04	0.018	0.033	0.024	NA	0.016	5.2e-03	2.1e-04	1.4e-03	NA	6.7e-03
16	TCGA	Thyroid Carcinoma	0.0480	0.0320	2.3e-04	0.022	0.028	0.025	NA	0.023	2.8e-03	9.6e-04	1.7e-03	NA	2.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Systolic Blood Pressure	12.5	62.5	90.6	-8.4	-6.8	-8.1	-7.4	-6.8	-7.5	-6.5	-8.3	-8.5	-7.7	-7.2	-9.5	-8.3	-6.4	-8.7	-9.5
Blood White Count	9.6	70.9	110.2	-10.5	-6.7	-8.2	-6.6	-9.1	-8.9	-6.7	-7.0	-9.3	-9.3	-7.5	-8.5	-9.1	-7.5	-9.0	-9.7
Osteoporosis (self-reported)	9.1	11.3	18.5	-3.0	-2.8	-3.8	-2.7	-3.7	-2.9	-4.3	-2.8	-3.1	-3.6	-3.7	-3.3	-3.6	-3.9	-3.3	-2.9
Impedance of leg (right)	7.5	36.5	79.7	-8.9	-2.9	-5.5	-5.8	-5.9	-6.5	-5.2	-3.5	-6.2	-6.5	-4.3	-7.1	-6.7	-5.2	-6.1	-7.6
Impedance of leg (left)	7.5	36.7	77.7	-8.8	-3.4	-5.7	-5.8	-6.0	-6.4	-5.3	-3.9	-6.2	-6.4	-4.2	-7.0	-6.6	-5.2	-6.1	-7.5
Headache pain in last month	7.0	12.0	16.9	-3.6	-2.5	-3.7	-3.9	-3.4	-3.9	-3.4	-2.5	-2.7	-3.5	-2.8	-3.7	-3.8	-3.5	-3.8	-4.1
Blood clot in the leg (DVT)	6.8	8.8	17.3	2.5	3.2	3.0	1.5	2.4	2.3	3.3	4.2	3.2	2.7	4.0	3.2	2.8	2.8	3.0	2.2
Medication: Atenolol	6.5	8.2	11.2	-2.9	-2.2	-3.0	-2.2	-3.1	-3.3	-2.7	-2.9	-3.1	-3.2	-2.4	-2.6	-3.1	-2.7	-2.9	-3.1
Systolic blood pressure, automated reading	6.4	18.5	28.8	-4.6	-3.8	-4.5	-3.9	-3.9	-3.8	-3.7	-4.7	-4.6	-4.2	-3.4	-5.3	-4.5	-3.1	-4.7	-5.4
Impedance of whole body	6.4	32.4	72.6	-8.5	-3.1	-5.1	-5.4	-5.6	-6.0	-4.6	-3.3	-6.1	-6.1	-4.0	-6.6	-6.2	-4.8	-5.9	-7.1
Blood Red Count	6.3	60.7	75.9	-7.6	-7.7	-7.5	-5.5	-7.9	-8.1	-8.2	-8.7	-7.9	-8.2	-8.4	-7.6	-7.8	-7.8	-8.2	-6.9
Deep venous thrombosis (DVT) (self-reported)	5.8	7.5	15.2	2.4	2.9	2.6	1.4	2.1	2.0	3.1	3.9	3.1	2.4	3.8	2.9	2.5	2.6	2.8	1.9
Birth weight of first child	5.6	10.1	19.9	2.1	3.8	4.4	2.8	4.5	3.3	3.5	3.2	2.9	3.7	1.8	2.4	3.3	3.1	2.2	2.6
Medication: Amlodipine	5.5	7.8	18.9	-4.3	-1.7	-2.6	-2.8	-2.4	-2.8	-2.1	-1.9	-3.1	-2.8	-2.4	-3.1	-2.9	-2.0	-3.0	-3.6
High blood pressure (mother)	4.9	6.8	9.8	-3.0	-3.0	-2.7	-2.4	-2.4	-2.4	-2.1	-1.9	-3.1	-2.7	-2.4	-2.9	-2.7	-2.0	-2.9	-2.8
Impedance of arm (right)	4.9	22.9	51.3	-7.2	-2.7	-4.4	-4.5	-4.6	-5.0	-4.0	-2.6	-5.0	-5.0	-3.4	-5.8	-5.2	-4.1	-4.9	-6.0
Supplements: Calcium	4.9	5.4	9.0	-1.5	-2.2	-2.9	-2.4	-2.5	-1.4	-2.6	-2.3	-1.2	-2.4	-2.1	-2.4	-2.7	-3.0	-2.4	-2.5
Pack years of smoking	4.8	7.1	12.0	-3.0	-2.9	-2.7	-3.5	-2.7	-2.5	-1.9	-3.0	-3.4	-2.6	-2.7	-1.7	-2.3	-2.1	-2.7	-2.1
Birth weight	4.7	10.2	17.0	3.2	2.7	3.4	2.6	3.8	4.1	3.0	3.1	3.3	3.7	2.5	3.1	3.3	3.0	2.9	2.9
Impedance of arm (left)	4.6	21.4	47.5	-6.9	-2.8	-4.1	-4.3	-4.6	-4.8	-3.7	-2.5	-4.9	-5.0	-3.3	-5.5	-5.0	-4.0	-4.8	-5.7
Number of self-reported non-cancer illnesses	4.6	8.0	12.2	-3.5	-2.3	-3.1	-2.1	-2.9	-3.1	-2.9	-1.9	-2.9	-3.3	-2.1	-2.6	-3.1	-2.9	-3.0	-3.2
Prospective memory result	4.5	5.6	12.3	1.9	1.6	2.4	2.9	2.1	1.8	2.8	3.5	1.4	2.0	2.7	2.2	2.4	2.5	2.4	2.2
Cardiovascular Disease	4.3	14.4	28.6	-4.9	-2.0	-4.0	-3.8	-2.6	-3.4	-2.5	-3.9	-4.4	-3.7	-2.9	-4.3	-4.0	-2.8	-4.3	-5.3
Migraine (self-reported)	4.3	5.4	10.8	-3.3	-1.1	-2.1	-0.6	-1.9	-2.5	-1.9	-1.9	-2.2	-2.6	-2.7	-3.0	-2.5	-2.0	-2.6	-2.8
Frequency of tenseness / restlessness in last 2 weeks	4.2	6.6	10.4	-2.1	-2.5	-3.2	-2.6	-2.5	-2.5	-2.5	-3.2	-2.3	-2.6	-2.5	-2.2	-2.6	-2.2	-2.7	-2.6
Leg fat percentage (right)	4.2	15.2	26.7	-5.0	-1.7	-4.0	-4.2	-4.4	-4.3	-3.7	-2.5	-3.1	-4.3	-2.6	-3.9	-4.4	-3.3	-4.0	-5.2
Severe depression (siblings)	4.0	4.4	7.4	-2.6	-2.0	-2.3	-2.1	-2.0	-2.2	-1.5	-1.3	-2.7	-2.3	-2.1	-1.8	-2.1	-2.0	-2.2	-2.1
Pack years adult smoking proportion	4.0	6.1	11.5	-2.7	-2.8	-2.5	-3.4	-2.5	-2.2	-1.7	-2.8	-3.3	-2.4	-2.5	-1.4	-2.1	-2.0	-2.5	-1.8
Hair/balding pattern: Pattern 4	3.9	9.4	15.1	3.9	2.7	3.1	2.9	3.3	2.6	3.3	3.0	2.9	3.1	3.5	2.9	3.1	3.0	3.1	2.5
Leg fat percentage (left)	3.7	13.4	23.2	-4.6	-1.8	-3.8	-4.0	-4.1	-4.0	-3.4	-2.5	-2.9	-4.0	-2.4	-3.6	-4.2	-3.1	-3.8	-4.8
Lung FEV1/FVC ratio	3.5	17.8	32.1	2.9	4.8	5.0	3.8	4.7	3.5	5.7	4.7	2.3	4.0	5.1	3.8	4.3	4.6	3.8	3.1
Hypertension (Self-reported)	3.5	9.8	20.2	-4.4	-1.9	-3.1	-3.4	-2.5	-3.3	-1.8	-2.7	-3.7	-3.2	-1.6	-3.5	-3.2	-2.0	-3.5	-4.5
Coronary Artery Disease (CAD)	3.4	4.0	5.6	2.3	2.3	1.4	2.3	2.1	1.6	1.9	1.1	2.2	2.4	1.6	2.3	2.2	2.1	2.0	1.9
Whole body fat-free mass	3.4	19.2	31.8	5.6	3.0	4.2	4.2	4.7	5.5	3.8	2.4	4.4	5.0	3.0	4.6	4.7	4.0	4.4	5.0
High blood pressure	3.3	9.3	20.5	-4.4	-1.6	-2.9	-3.2	-2.3	-3.4	-1.7	-2.5	-3.6	-3.1	-1.4	-3.5	-3.2	-1.9	-3.4	-4.5
Trunk fat-free mass	3.3	18.8	31.4	5.5	3.1	4.2	4.3	4.8	5.6	3.7	2.0	4.3	5.0	2.8	4.5	4.7	3.9	4.4	5.0
Happiness	3.3	4.0	5.9	-1.8	-1.6	-2.4	-1.3	-2.0	-2.3	-2.0	-2.3	-1.6	-2.0	-2.1	-1.9	-2.0	-2.0	-2.2	-2.1
Diastolic blood pressure, automated reading	3.3	10.3	22.1	-3.9	-2.2	-2.8	-3.2	-2.1	-3.4	-2.3	-2.7	-3.2	-2.9	-2.3	-4.5	-3.4	-2.2	-3.9	-4.7
Medication: Levothyroxine sodium	3.2	5.5	8.2	2.6	1.5	1.9	2.3	2.0	2.5	1.9	1.8	2.8	2.5	2.4	2.4	2.5	2.1	2.8	2.9
Whole body water mass	3.2	18.5	32.0	5.7	2.9	4.1	4.1	4.6	5.4	3.6	2.3	4.4	4.9	2.9	4.5	4.6	3.9	4.3	5.0
Leg predicted mass (right)	3.2	17.0	30.4	5.5	2.5	3.9	3.9	4.3	5.2	3.6	2.4	4.2	4.6	2.9	4.4	4.4	3.8	4.1	4.7
Hair/balding pattern: Pattern 2	3.1	3.9	9.9	-1.6	-1.7	-2.2	-2.0	-1.6	-1.1	-2.4	-3.1	-1.2	-1.6	-2.6	-1.7	-1.9	-2.5	-1.9	-1.3
Trunk predicted mass	3.1	17.9	30.6	5.4	3.0	4.0	4.2	4.6	5.5	3.5	1.9	4.3	4.9	2.6	4.4	4.6	3.8	4.2	4.9
Body fat percentage	3.1	12.3	21.9	-4.7	-1.8	-3.6	-3.9	-4.1	-3.8	-3.2	-2.2	-2.9	-3.9	-2.3	-3.4	-3.9	-2.9	-3.5	-4.5
Leg fat-free mass (right)	3.1	16.5	29.7	5.5	2.5	3.9	3.8	4.3	5.1	3.6	2.3	4.1	4.6	2.8	4.3	4.4	3.7	4.1	4.7
Leg pain on walking	3.0	3.7	6.7	1.4	2.6	1.7	2.1	2.0	1.7	1.8	1.3	2.1	2.2	2.3	2.1	1.9	2.0	2.0	1.3
Sitting height	2.9	20.9	30.4	4.5	3.8	4.9	4.7	5.5	5.3	5.0	3.2	3.7	5.2	3.6	4.1	5.0	5.0	4.5	4.4
Peak expiratory flow (PEF)	2.8	6.4	10.8	1.8	2.3	2.8	3.0	3.0	3.3	3.3	1.3	1.2	2.9	1.6	2.5	2.8	2.9	2.2	2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.7	3.1	6.1	-2.0	-2.2	-1.4	-1.2	-2.4	-1.7	-1.4	-1.0	-2.5	-2.2	-1.6	-1.5	-1.8	-1.4	-1.8	-1.7
Leg fat-free mass (left)	2.6	13.8	23.8	4.9	2.5	3.6	3.4	3.9	4.6	3.3	2.4	3.8	4.1	2.7	4.0	4.0	3.4	3.7	4.1
Trunk fat percentage	2.6	10.3	19.5	-4.4	-1.6	-3.2	-3.6	-3.8	-3.4	-2.9	-1.9	-2.7	-3.6	-2.0	-3.1	-3.6	-2.5	-3.2	-4.2
Townsend deprivation index at recruitment	2.6	3.6	5.3	-2.1	-1.0	-2.0	-1.8	-1.8	-2.3	-1.6	-1.6	-1.8	-2.1	-1.8	-1.9	-2.0	-1.5	-2.0	-2.3
Medication: Blood pressure	2.6	4.9	7.5	-2.7	-1.1	-2.5	-2.6	-1.5	-2.0	-2.0	-2.2	-2.4	-2.1	-1.9	-2.5	-2.3	-2.1	-2.3	-2.7
Tinnitus: Yes, but not now, but have in the past	2.5	2.6	5.2	-1.6	-1.1	-2.0	-1.0	-1.5	-0.8	-2.1	-2.0	-0.9	-1.4	-2.3	-1.6	-1.6	-2.1	-1.6	-1.2
Leg predicted mass (left)	2.5	13.4	23.2	4.8	2.5	3.5	3.4	3.8	4.6	3.2	2.3	3.8	4.1	2.6	3.9	3.9	3.4	3.6	4.1
Arm fat-free mass (right)	2.5	12.6	22.8	4.8	2.5	3.3	3.5	3.7	4.6	2.8	1.6	3.7	4.0	2.2	3.9	3.8	3.2	3.6	4.2
Heart disease (mother)	2.5	3.1	6.4	-2.5	-1.9	-2.2	-1.4	-2.0	-1.6	-1.3	-0.8	-1.1	-1.9	-1.3	-1.9	-2.0	-1.7	-1.8	-1.9
Qualifications: College or University degree	2.4	7.6	12.2	-2.8	-2.1	-2.4	-3.4	-2.0	-2.2	-2.3	-2.0	-2.2	-2.6	-3.2	-3.5	-3.1	-3.0	-3.3	-3.2
Arm predicted mass (right)	2.4	12.3	21.3	4.6	2.5	3.3	3.4	3.6	4.6	2.8	1.6	3.6	3.9	2.2	3.8	3.8	3.2	3.6	4.1
Alzheimer’s Disease (including proxy)	2.3	3.3	5.4	1.9	1.4	1.8	1.7	1.3	1.6	2.3	1.7	2.3	1.9	1.8	1.6	1.8	2.2	1.7	1.7
Blood Platelet Count	2.3	26.4	38.6	-4.8	-2.9	-5.7	-5.9	-6.2	-5.5	-5.1	-3.7	-3.3	-5.5	-4.4	-5.2	-5.9	-5.8	-5.2	-5.8
Arm predicted mass (left)	2.3	11.9	21.4	4.6	2.6	3.2	3.2	3.6	4.5	2.7	1.7	3.6	3.9	2.3	3.8	3.7	3.1	3.5	4.0
Depressed Affect (Nagel 2018)	2.2	4.7	11.6	-1.3	-1.5	-2.8	-2.3	-2.1	-2.0	-2.3	-3.4	-1.5	-2.0	-2.4	-1.7	-2.2	-2.2	-2.1	-2.1
Alzheimer’s Disease (in mother)	2.1	2.5	4.5	1.3	1.3	2.1	1.7	1.2	1.6	1.8	1.0	1.8	1.6	1.3	1.3	1.7	2.1	1.5	1.6
Hypothyroidism/myxoedema (self-reported)	2.1	4.1	6.5	2.3	0.8	1.7	1.7	1.6	2.2	1.9	1.8	2.0	2.0	2.2	2.4	2.2	2.0	2.3	2.5
Illnesses of father: Heart disease	2.1	2.9	6.7	0.9	1.6	2.0	1.9	2.2	2.6	1.6	1.9	1.3	1.9	1.3	1.2	1.7	1.7	1.4	1.2
Friendships satisfaction	2.1	2.6	4.9	-1.8	-1.2	-2.0	-1.1	-1.6	-1.7	-1.2	-1.4	-1.2	-1.6	-1.1	-1.6	-1.8	-1.5	-1.9	-2.2
Miserableness	2.1	3.6	6.8	-1.4	-0.8	-2.5	-2.2	-1.7	-1.8	-1.9	-2.6	-1.2	-1.7	-1.8	-1.8	-2.0	-2.0	-2.0	-2.2
Basal metabolic rate	2.1	11.7	20.7	4.5	2.5	3.2	3.2	3.6	4.5	2.8	1.8	3.6	3.9	2.3	3.6	3.6	3.1	3.4	3.8
Vascular/heart problems diagnosed by doctor	2.1	5.6	14.1	3.8	0.9	2.2	2.5	1.8	2.8	1.1	1.9	2.9	2.5	0.7	2.6	2.4	1.3	2.5	3.6
HbA1C	2.0	2.3	5.5	1.5	0.7	1.4	2.4	1.7	1.3	2.0	1.2	1.0	1.2	1.5	1.3	1.5	1.9	1.4	1.4
Hypothyroidism (self reported)	2.0	4.5	7.4	1.9	0.9	1.8	1.8	1.8	2.3	2.1	2.4	1.6	2.0	2.3	2.5	2.4	2.2	2.5	2.7
Illnesses of mother	1.9	2.3	4.7	2.2	1.9	1.4	1.5	1.7	1.1	0.6	0.9	1.9	1.7	1.2	1.5	1.6	0.8	1.7	1.8
Arm fat-free mass (left)	1.9	9.4	17.5	4.2	2.1	2.9	2.9	3.2	4.2	2.4	1.4	3.1	3.5	1.9	3.3	3.3	2.8	3.1	3.6
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	4.8	0.8	2.0	1.5	1.3	1.7	2.2	1.1	0.7	1.3	1.8	0.9	1.4	1.4	1.2	1.6	1.4
Length of working week for main job	1.8	2.0	4.7	1.8	0.7	1.4	0.4	1.2	1.6	1.3	1.5	0.2	1.2	1.2	2.2	1.6	1.3	1.5	2.0
Exposure to tobacco smoke at home	1.8	2.0	3.8	-1.0	-0.2	-1.7	-1.1	-1.2	-1.5	-1.2	-2.0	-0.4	-1.3	-1.4	-1.8	-1.6	-1.5	-1.8	-1.9
Tense / ‘highly strung’	1.8	3.0	4.5	-1.3	-1.9	-2.1	-1.4	-1.6	-0.4	-1.9	-2.1	-1.9	-1.7	-1.8	-1.8	-1.8	-1.4	-1.7	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	4.6	-1.4	0.2	-1.9	-1.5	-1.4	-1.3	-0.9	-2.2	-1.1	-1.5	-1.5	-1.3	-1.6	-1.3	-1.5	-2.0
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.7	5.2	-1.5	-0.3	-2.1	-1.7	-1.5	-1.4	-1.5	-2.0	-1.3	-1.6	-1.5	-1.6	-1.9	-1.6	-1.8	-2.3
Loneliness, isolation	1.7	2.4	8.6	-0.7	-0.3	-2.2	-1.6	-0.9	-0.9	-1.5	-2.9	-1.1	-1.0	-1.9	-1.1	-1.5	-1.5	-1.7	-1.9
Medication for cholesterol	1.7	2.6	6.0	1.5	-0.0	2.1	1.6	0.9	1.4	1.4	2.4	1.1	1.3	1.8	1.6	1.6	1.6	1.7	2.0
Schizophrenia (2018)	1.6	3.3	7.2	-1.7	-1.6	-2.0	-2.7	-1.5	-1.6	-0.7	-1.7	-2.2	-1.9	-1.2	-1.5	-1.8	-1.3	-2.1	-2.5
Bipolar Disorder (2011)	1.6	1.6	4.2	0.5	1.3	1.3	0.6	1.0	0.8	1.6	2.0	0.7	1.0	1.8	1.4	1.3	1.7	1.3	0.6
Crohns Disease (2012)	1.6	2.5	6.0	1.1	0.9	2.0	1.7	1.9	1.1	2.4	1.5	0.7	1.4	1.6	1.3	1.7	2.1	1.5	1.6
Fasting Glucose	1.6	1.9	3.4	1.5	0.7	1.2	1.5	1.2	1.1	1.6	1.8	-0.3	1.1	1.7	1.8	1.4	1.6	1.2	1.1
Frequency of depressed mood in last 2 weeks	1.6	2.2	5.3	-1.0	-0.6	-2.2	-1.7	-1.6	-0.7	-1.2	-2.3	-1.3	-1.4	-1.4	-1.0	-1.6	-1.4	-1.4	-1.7
Bipolar Disorder or Schizophrenia	1.5	3.6	11.0	-2.0	-1.8	-1.9	-3.3	-1.9	-1.7	-0.9	-1.0	-2.3	-2.1	-0.9	-1.4	-1.8	-1.2	-2.0	-2.5
Depression (Nagel 2018)	1.5	2.3	7.0	-0.9	0.1	-2.4	-1.7	-1.5	-0.8	-1.5	-2.6	-0.7	-1.2	-1.4	-1.2	-1.6	-1.6	-1.4	-1.9
Neuroticism	1.5	3.5	13.7	-0.8	-1.0	-2.4	-0.8	-1.3	-1.4	-1.9	-3.7	-1.0	-1.4	-2.3	-2.0	-1.9	-1.5	-2.0	-2.3
Ever had hysterectomy (womb removed)	1.5	1.7	3.1	-1.0	-1.0	-1.1	-1.8	-1.5	-0.9	-1.8	-1.4	-1.4	-1.3	-1.2	-1.0	-1.4	-1.4	-1.1	-1.0
Noisy workplace	1.5	1.8	4.3	0.5	1.1	1.5	1.3	1.3	0.9	1.4	0.8	0.7	1.2	0.9	1.9	1.7	1.6	1.7	2.1
Mouth/teeth dental problems: Dentures	1.5	2.6	7.3	2.3	1.1	0.9	1.4	1.5	1.9	1.1	-0.4	2.7	1.7	1.9	1.9	1.6	1.4	1.4	1.2
Worry too long after embarrassment	1.5	2.5	5.1	-1.0	-0.4	-1.8	-1.4	-0.7	-0.6	-2.0	-2.3	-1.2	-1.1	-2.2	-2.2	-1.6	-1.3	-1.7	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	4.8	-1.1	-0.2	-1.9	-1.0	-1.3	-1.1	-1.1	-1.9	-0.4	-1.4	-1.2	-1.2	-1.6	-1.4	-1.7	-2.2
Age started oral contraceptive pill	1.5	1.8	3.2	1.2	1.2	1.7	1.8	1.8	1.2	1.5	1.1	1.2	1.4	1.4	1.1	1.4	1.1	1.1	1.0
Basal cell carcinoma (self-reported)	1.5	1.8	5.1	-1.9	-1.8	-0.7	-0.4	-1.8	-1.3	-0.7	-0.2	-2.2	-1.7	-0.9	-1.0	-1.2	-0.6	-1.4	-1.2
Crohns Disease (2017)	1.4	3.0	4.7	1.4	1.6	1.8	1.9	2.0	1.5	2.2	1.0	1.4	1.8	1.7	1.7	1.9	1.8	1.7	1.9
Eye problems/disorders: None of the above	1.4	1.6	2.4	1.2	1.4	1.1	0.4	1.4	1.3	1.2	1.2	1.5	1.5	0.9	1.5	1.3	0.9	1.5	1.4
Arm fat percentage (left)	1.4	5.4	8.9	-2.8	-1.3	-2.5	-2.9	-3.0	-2.3	-2.2	-1.4	-1.6	-2.6	-1.6	-2.0	-2.6	-2.0	-2.4	-2.9
Alcohol drinker status: Never	1.4	1.7	3.0	-0.9	-0.6	-1.1	-1.2	-1.4	-1.2	-1.7	-1.1	-0.6	-1.3	-1.3	-1.5	-1.5	-1.5	-1.6	-1.6
Sensitivity / hurt feelings	1.3	2.2	4.7	2.2	1.5	1.1	1.8	1.9	1.6	0.9	0.2	1.9	1.9	0.9	1.4	1.6	1.4	1.2	1.3
Hand grip strength (right)	1.3	3.4	5.4	2.3	1.3	1.9	0.9	2.2	2.0	1.4	2.2	1.6	2.2	1.6	2.0	2.0	1.6	1.8	1.9
Age when periods started (menarche)	1.3	3.1	6.2	1.1	2.1	2.2	2.5	1.9	1.1	1.9	1.6	0.9	1.7	1.8	1.4	1.8	1.9	1.8	1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.9	5.3	1.5	2.2	1.4	1.5	1.9	1.3	1.6	2.3	2.2	1.6	2.1	1.5	1.4	1.5	1.4	0.7
Supplements: Glucosamine	1.3	1.7	2.5	1.4	0.3	1.6	1.6	1.4	1.2	1.3	1.6	0.9	1.2	1.3	1.1	1.4	1.5	1.2	1.4
Falls in the last year	1.3	1.7	5.6	-1.2	-1.3	-1.8	-2.0	-1.1	-2.4	-0.9	-0.9	-1.2	-1.4	-0.3	-0.7	-1.1	-1.1	-1.0	-1.2
Medication: Cholesterol lowering	1.3	2.0	5.5	0.9	2.3	1.3	1.5	1.2	1.3	1.5	1.4	1.1	1.1	2.0	1.4	1.2	1.7	1.4	0.4
Pulse wave reflection index	1.3	1.7	4.3	-2.1	-1.2	-1.6	-1.1	-1.3	-1.3	-0.8	-1.0	-1.2	-1.5	-0.8	-1.4	-1.4	-1.0	-1.1	-1.3
Knee pain experienced in last month	1.3	2.1	4.4	1.2	1.5	1.5	0.8	2.1	1.4	2.1	1.9	1.0	1.6	2.1	0.2	1.0	1.7	0.7	-0.3
Long-standing illness, disability or infirmity	1.3	2.0	4.0	-2.0	-1.1	-1.5	-0.5	-1.8	-1.4	-1.5	-0.5	-1.9	-1.8	-1.1	-1.0	-1.6	-1.2	-1.4	-1.4
LDL Cholesterol	1.2	2.0	3.1	0.8	1.2	1.4	1.5	1.6	1.8	1.2	1.3	0.9	1.4	1.2	1.4	1.5	1.6	1.7	1.6
Hand grip strength (left)	1.2	3.3	7.1	2.1	2.0	1.3	1.2	2.7	2.2	0.9	1.2	2.6	2.6	1.1	1.4	1.8	1.2	1.7	1.5
Stomach or abdominal pain in last month	1.2	1.5	2.3	-1.1	-1.3	-1.4	-0.9	-1.4	-1.5	-1.2	-1.4	-0.7	-1.4	-1.0	-0.9	-1.3	-1.4	-1.3	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	5.6	0.8	2.1	1.6	0.6	2.0	1.5	2.0	2.4	1.5	1.5	2.3	1.6	1.5	1.7	1.3	0.7
Pulse rate, automated reading	1.2	3.8	5.8	2.1	1.7	2.2	2.4	1.8	1.5	1.8	1.4	2.3	1.9	1.8	1.9	2.0	1.8	1.9	2.3
Supplements: Vitamin C	1.2	1.4	5.0	2.2	0.1	0.9	0.6	1.1	0.5	0.5	1.1	1.1	1.0	1.2	1.5	1.2	0.7	1.4	1.9
Commuting to job workplace: Walk	1.2	1.3	4.6	-0.6	-2.1	-0.4	-1.0	-1.5	-2.1	-0.1	0.3	-2.1	-1.3	-0.1	-0.6	-0.8	-0.3	-0.8	-0.7
Mother’s age at death	1.2	1.5	3.3	1.0	0.2	1.2	1.3	0.8	1.4	1.3	0.6	0.9	1.3	1.1	1.8	1.5	1.1	1.3	1.7
Eye problems/disorders: Glaucoma	1.2	1.5	3.9	2.0	1.0	1.1	1.2	0.9	1.1	0.8	1.1	1.4	1.1	1.5	1.4	1.1	0.7	1.3	1.2
Pain type(s) experienced in last month: Hip pain	1.2	1.5	3.5	1.1	1.1	0.8	1.0	0.7	0.3	0.9	1.9	1.4	1.1	1.8	1.4	1.2	1.3	1.6	1.1
Heart disease (siblings)	1.2	1.5	2.8	0.7	1.3	1.1	1.5	1.0	1.2	1.3	1.7	1.1	1.2	1.5	0.9	1.1	1.5	1.4	0.9
Neuroticism (Nagel 2018)	1.1	2.7	10.7	-1.0	-0.6	-2.2	-1.3	-1.3	-0.9	-1.9	-3.3	-0.8	-1.2	-2.2	-1.4	-1.6	-1.4	-1.5	-1.7
Waist Hip Ratio (WHR)	1.1	5.1	12.4	-2.6	-1.6	-2.6	-2.3	-3.5	-2.9	-2.2	-1.5	-1.6	-2.9	-1.2	-1.5	-2.4	-2.4	-1.8	-1.8
Heart attack	1.1	1.4	4.2	0.8	0.8	1.1	2.1	0.8	0.0	1.2	0.6	0.5	1.0	0.9	1.6	1.5	1.4	1.5	1.7
Arm fat percentage (right)	1.1	4.2	7.2	-2.6	-0.9	-2.2	-2.7	-2.6	-2.0	-1.9	-1.2	-1.4	-2.3	-1.2	-1.7	-2.3	-1.6	-2.0	-2.7
Pulse wave Arterial Stiffness index	1.1	1.2	5.0	0.4	1.6	0.6	1.1	1.0	1.1	0.8	0.2	2.2	1.2	1.1	0.7	1.0	1.2	1.0	0.7
Medication: Paracetamol	1.1	1.9	3.6	-1.8	-1.8	-1.3	-1.8	-1.6	-1.9	-0.4	-0.0	-1.3	-1.5	-0.1	-1.1	-1.3	-1.1	-1.2	-1.6
Medication for pain relief, constipation, heartburn	1.1	1.8	3.5	1.7	0.8	1.4	1.7	1.4	1.6	0.9	0.9	1.1	1.6	0.6	1.2	1.5	1.2	1.4	1.9
Medication: Blood pressure	1.1	2.0	6.9	-2.6	-0.0	-1.3	-1.3	-1.0	-1.2	-0.6	-1.3	-1.3	-1.4	-0.4	-1.6	-1.4	-0.4	-1.4	-2.4
Mood swings	1.1	2.0	4.7	-1.2	-0.9	-1.8	-2.2	-1.0	-1.0	-1.3	-1.8	-1.0	-1.1	-1.2	-1.4	-1.5	-1.5	-1.3	-1.8
Financial situation satisfaction	1.1	1.4	3.8	-2.0	-0.6	-0.9	-1.6	-1.3	-1.4	-0.1	-0.7	-1.6	-1.4	-0.8	-0.8	-1.1	-0.6	-1.1	-1.4
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.9	1.7	1.3	0.5	1.3	1.4	1.5	1.0	0.1	1.6	1.4	0.7	1.0	1.1	1.0	0.7	0.5
Irritable Bowel Disease (IBD)	1.0	2.4	3.5	1.6	1.7	1.3	1.7	1.7	1.0	1.8	1.0	1.9	1.7	1.5	1.4	1.6	1.4	1.7	1.6
Multivitamins +/- minerals	1.0	1.3	2.6	1.6	1.0	1.4	1.0	1.4	1.1	1.1	1.5	1.0	1.2	1.2	0.7	1.0	1.1	0.9	0.7
Waist circumference	1.0	3.8	7.3	-2.0	-1.2	-2.4	-2.3	-2.7	-1.5	-2.5	-1.9	-1.1	-2.1	-1.6	-1.4	-2.2	-2.0	-1.7	-1.9
Medication: Ramipril	1.0	1.3	4.2	-1.3	0.4	-1.5	-2.1	-0.7	-0.7	-0.7	-1.4	-0.9	-0.8	-0.9	-0.8	-1.1	-1.0	-1.0	-1.6
Neuroticism score	1.0	2.1	6.7	-0.7	-0.8	-2.0	-1.2	-1.0	-0.7	-1.8	-2.6	-0.9	-1.1	-1.8	-1.4	-1.4	-1.4	-1.5	-1.7
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	9.6	0.4	1.7	2.1	3.0	2.4	3.1	2.4	0.7	0.2	2.1	0.8	1.2	2.0	2.2	1.2	1.2
Pulse rate	1.0	1.7	4.7	2.2	1.0	1.5	0.9	1.4	1.1	0.8	0.9	2.1	1.5	1.1	0.9	1.3	1.0	0.9	1.3
Comparative body size at age 10	1.0	2.7	6.5	2.5	1.0	1.1	1.8	1.5	1.4	1.5	1.1	1.9	1.6	1.3	2.1	1.7	1.3	1.7	1.9
Age at first live birth	1.0	1.7	4.4	-1.0	0.1	-1.1	-1.4	-0.9	-1.4	-1.4	-0.5	-0.9	-1.2	-1.1	-1.8	-1.7	-1.7	-1.5	-2.1
Medication: Omeprazole	1.0	1.2	3.3	1.6	1.8	0.6	1.0	0.8	1.7	0.5	0.4	1.8	1.1	1.1	0.9	0.8	0.7	1.0	0.4
Leg fat mass (right)	1.0	3.8	7.3	-2.4	-0.7	-2.2	-2.3	-2.3	-1.8	-2.0	-1.5	-1.2	-2.1	-1.4	-1.8	-2.3	-1.6	-2.0	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.1	2.0	-0.2	-1.4	-1.1	-1.2	-1.1	-1.0	-1.3	-1.4	-0.5	-1.1	-1.2	-1.1	-1.1	-1.1	-1.0	-0.7
Average weekly champagne plus white wine intake	1.0	1.4	3.5	0.4	0.2	1.4	0.7	1.0	0.8	1.9	1.1	0.1	1.1	1.4	1.5	1.4	1.4	1.3	1.3
Guilty feelings	1.0	1.5	5.0	-1.0	0.3	-1.8	-0.8	-0.7	-0.8	-1.0	-2.2	-0.4	-0.8	-1.3	-1.3	-1.3	-0.9	-1.4	-2.0
Ever depressed for a whole week	1.0	1.2	2.8	-0.6	-0.2	-1.3	-1.6	-1.3	-0.7	-1.1	-1.7	-0.4	-0.9	-1.2	-1.0	-1.2	-1.1	-1.0	-1.2
Alzheimer’s Disease (in father)	0.9	1.0	2.1	1.3	0.6	0.5	0.8	0.4	0.4	1.2	1.4	1.2	0.8	1.2	1.2	0.8	1.1	1.2	1.1
Prostate Cancer	0.9	1.3	2.4	0.8	0.9	1.3	0.8	1.5	1.2	0.8	0.6	0.7	1.5	0.8	1.3	1.4	1.2	1.4	1.4
Primary Biliary Cirrhosis	0.9	1.3	2.7	-1.2	-1.2	-1.1	0.2	-0.9	-0.8	-1.0	-1.4	-1.4	-1.3	-1.6	-1.4	-1.1	-0.8	-1.3	-0.8
Schizophrenia (2014)	0.9	2.0	4.0	-1.2	-1.5	-1.7	-1.7	-1.2	-1.7	-0.4	-0.9	-1.8	-1.6	-0.7	-1.2	-1.4	-0.8	-1.6	-2.0
Qualifications: None of the above	0.9	1.9	4.3	1.4	0.2	1.0	2.0	0.9	0.8	1.2	0.3	1.3	1.1	1.2	2.1	1.7	1.5	1.7	2.0
Illnesses of siblings	0.9	1.3	6.1	-0.3	0.5	-0.7	-0.8	-0.6	-0.4	-1.5	-1.3	-0.3	-0.8	-2.5	-1.4	-1.2	-1.4	-1.1	-1.1
Chest pain or discomfort	0.9	1.3	3.2	-0.1	-0.1	-1.5	-0.9	-1.1	-0.9	-1.8	-1.8	-0.3	-1.0	-1.7	-0.4	-1.1	-1.5	-0.8	-0.7
Family relationship satisfaction	0.9	1.1	2.1	-0.7	-1.3	-1.1	-1.0	-1.1	-1.4	-0.5	-0.2	-1.4	-1.1	-0.5	-0.9	-1.2	-0.9	-1.2	-1.4
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.2	-0.5	-1.1	-1.1	-0.8	-0.8	-0.9	-1.5	-1.0	-0.5	-0.9	-1.2	-1.2	-1.0	-1.2	-1.2	-1.0
Eye problems/disorders: Cataract	0.9	1.0	1.9	-1.0	-1.3	-1.0	0.3	-1.3	-0.7	-0.9	-0.8	-1.4	-1.1	-0.7	-1.1	-1.0	-0.6	-1.0	-1.0
Commuting to job workplace: Public transport	0.9	1.0	3.2	-0.3	-0.3	-0.9	-1.0	-0.7	-0.2	-1.3	-1.8	0.1	-0.7	-1.6	-1.2	-1.1	-1.4	-1.1	-0.8
Ever smoked	0.9	1.7	3.1	0.4	1.7	1.4	1.3	1.3	1.3	1.8	1.4	0.6	1.1	1.3	1.2	1.2	1.8	1.2	0.7
Number of operations (self-reported)	0.9	1.4	4.8	1.3	1.6	0.5	2.2	0.6	1.3	0.3	-0.0	0.9	1.0	0.6	1.7	1.0	0.8	1.4	1.3
Irritability	0.9	1.6	3.1	-0.4	-1.7	-1.5	-1.8	-1.3	-0.7	-1.1	-1.2	-1.3	-1.3	-0.9	-1.1	-1.3	-1.3	-1.3	-1.3
Ovarian Cancer	0.8	1.1	2.4	-1.2	-1.1	-0.4	-1.0	-1.2	-1.4	-0.5	0.6	-1.5	-1.3	-0.0	-1.2	-1.1	-0.6	-0.9	-1.2
Trunk fat mass	0.8	3.6	7.1	-2.7	-0.7	-2.0	-2.3	-2.3	-1.7	-1.8	-1.4	-1.4	-2.0	-1.1	-1.7	-2.1	-1.4	-1.9	-2.7
Pain all over the body in last month	0.8	0.8	3.2	0.3	-0.4	0.9	1.2	0.4	0.5	0.6	1.0	0.1	0.5	0.4	1.4	1.1	0.9	1.1	1.8
Worrier / anxious feelings	0.8	1.4	4.1	-1.1	-0.8	-1.3	-0.2	-0.9	-0.5	-1.1	-1.8	-1.3	-0.9	-2.0	-1.3	-1.1	-0.9	-1.4	-1.3
Lung cancer (father)	0.8	0.9	1.7	1.0	1.3	0.7	0.8	0.7	0.9	1.0	-0.3	1.1	0.8	1.1	1.3	1.0	1.1	0.9	0.9
Emphysema/chronic bronchitis	0.8	0.9	2.7	-0.4	-0.4	-1.5	-0.9	-1.4	-0.8	-1.2	-1.6	0.5	-0.9	-1.0	-0.3	-0.9	-1.1	-0.6	-0.5
Overall health rating	0.8	1.7	4.8	-1.1	-0.1	-1.9	-1.0	-1.4	-0.7	-1.7	-2.2	-0.6	-1.3	-1.2	-0.9	-1.5	-1.4	-1.2	-1.5
Had major operations	0.8	0.9	6.0	1.0	1.4	0.3	2.4	0.1	0.1	0.0	-0.3	0.9	0.7	0.1	1.2	0.7	0.4	1.0	1.1
Heart attack/myocardial infarction (self-reported)	0.8	1.0	3.7	0.6	0.5	0.9	1.9	0.7	-0.1	0.9	0.4	0.3	0.8	0.7	1.4	1.3	1.3	1.2	1.5
Worry (Nagel 2018)	0.7	1.5	6.5	-0.7	-0.7	-1.6	-0.5	-0.9	-0.5	-1.5	-2.6	-0.7	-0.8	-1.8	-1.0	-1.1	-1.1	-1.1	-1.1
HDL Cholesterol	0.7	1.2	2.3	1.4	1.1	1.4	0.7	1.3	1.5	1.1	1.1	1.0	1.2	0.5	0.4	1.1	1.2	1.0	1.0
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.5	-1.4	-0.6	-0.5	-1.6	-0.6	-0.7	-0.2	-1.1	-0.7	-0.7	-0.6	-0.8	-0.8	-0.5	-1.0	-1.2
Heel T-Score	0.7	5.7	13.8	2.6	3.0	1.8	1.9	2.2	2.1	1.6	1.7	3.7	2.4	2.5	2.6	2.3	2.0	2.5	2.1
Diabetes (mother)	0.7	0.9	2.5	0.7	1.6	0.7	1.3	1.2	1.3	0.9	0.3	0.9	1.1	0.8	0.8	0.8	0.7	0.6	0.3
Fed-up feelings	0.7	1.3	2.6	-0.7	-0.7	-1.6	-0.6	-1.1	-1.0	-1.4	-1.6	-1.1	-1.1	-1.5	-0.9	-1.1	-1.3	-0.8	-0.7
Hearing difficulty/problems with background noise	0.7	1.1	3.6	-1.9	-1.0	-1.0	-0.0	-1.0	-1.3	0.2	-0.8	-1.8	-1.2	-0.2	-0.7	-0.8	-0.2	-1.0	-1.2
Had other major operations	0.7	0.9	2.9	0.5	1.0	0.5	0.5	0.4	1.7	0.8	1.7	1.0	0.7	1.1	1.0	0.6	0.9	0.9	0.4
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.5	-1.3	0.2	-1.0	-1.2	-0.7	-0.7	-0.7	-1.6	-0.4	-0.7	-1.0	-1.0	-0.9	-0.8	-0.8	-1.1
Medication: Lansoprazole	0.7	0.7	2.9	0.4	1.3	0.8	1.7	1.1	-0.1	0.3	0.5	0.9	0.9	0.5	1.1	0.9	0.5	0.6	0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	7.5	-0.3	1.8	1.5	2.2	2.2	2.7	1.9	0.4	-0.3	1.7	0.2	0.6	1.4	1.6	0.5	0.5
Breastfed as a baby	0.7	0.8	2.1	0.6	0.3	1.1	0.5	0.5	0.5	1.0	1.1	0.2	0.6	1.4	1.4	1.0	0.9	1.1	1.1
Pulse wave peak to peak time	0.7	0.9	4.5	-0.3	-1.4	-0.4	-1.0	-0.7	-0.7	-0.6	-0.1	-2.1	-0.9	-1.1	-0.6	-0.8	-1.0	-0.9	-0.5
Whole body fat mass	0.7	2.8	5.5	-2.3	-0.6	-1.8	-2.0	-2.1	-1.6	-1.6	-1.2	-1.2	-1.8	-1.1	-1.5	-1.9	-1.2	-1.7	-2.4
Age at last live birth	0.7	1.0	2.3	0.1	0.8	-1.4	-0.6	-0.2	-0.3	-1.3	-1.2	-0.0	-0.5	-1.1	-1.3	-1.2	-1.3	-0.9	-1.5
Ever had bowel cancer screening	0.7	0.8	6.1	0.2	0.3	0.8	2.5	0.3	-0.2	0.4	0.7	-0.3	0.1	0.5	1.0	0.9	1.2	0.8	0.9
Back pain experienced in last month	0.7	1.1	3.1	-0.3	-1.7	-1.3	-1.4	-1.8	-1.7	-0.4	0.3	0.2	-1.1	0.9	-0.1	-0.8	-0.8	-0.4	-0.7
Illnesses of father: None of the above (group 1)	0.7	0.8	2.2	0.1	-1.1	-0.9	-0.6	-0.9	-1.1	-1.4	-1.5	-0.7	-0.8	-1.0	-0.2	-0.7	-1.3	-0.4	0.1
Leg fat mass (left)	0.7	2.7	5.3	-2.0	-0.6	-1.9	-2.0	-2.0	-1.4	-1.6	-1.4	-1.0	-1.7	-1.1	-1.5	-1.9	-1.3	-1.7	-2.3
Smoking Status	0.6	1.4	2.4	1.0	1.0	0.7	1.2	1.2	1.4	1.5	0.4	1.2	1.3	1.3	1.3	1.3	1.5	1.4	1.1
Average weekly spirits intake	0.6	0.8	4.0	0.4	0.3	1.0	0.4	0.2	0.3	0.8	2.0	0.3	0.2	1.5	1.2	0.7	0.7	0.9	0.8
Relative age of first facial hair	0.6	1.3	4.3	1.3	0.9	0.9	2.1	0.8	0.5	0.8	0.8	1.0	1.0	1.3	1.2	1.2	1.1	1.1	1.2
Medication: Metformin	0.6	0.9	2.0	-0.7	-0.6	-1.4	0.3	-1.2	-1.0	-1.2	-1.4	-0.3	-1.0	-0.7	-0.9	-1.0	-0.9	-0.7	-0.9
Maternal smoking around birth	0.6	0.8	4.2	-0.4	0.5	-0.8	-1.0	-0.6	-0.5	-1.0	-2.0	-0.2	-0.7	-1.2	-0.6	-0.8	-1.0	-0.7	-0.6
Nervous feelings	0.6	1.2	5.3	-0.7	0.9	-1.2	-0.2	-0.7	-0.3	-1.4	-2.3	-0.4	-0.6	-1.9	-1.1	-1.0	-1.1	-0.7	-0.8
Hip circumference	0.6	2.8	4.2	-1.8	-1.1	-1.8	-1.9	-1.5	-0.3	-2.0	-1.9	-1.1	-1.5	-1.9	-1.8	-1.8	-1.4	-1.7	-2.0
Comparative height size at age 10	0.6	3.3	8.2	1.5	1.4	1.7	2.9	1.7	2.4	1.7	0.6	0.8	2.0	1.2	1.8	2.0	2.1	2.0	2.0
Diabetes diagnosed by doctor	0.6	1.1	3.0	-1.5	-0.4	-1.2	0.4	-1.1	-0.7	-0.8	-1.7	-1.3	-1.1	-0.8	-0.8	-1.0	-0.5	-1.0	-1.1
Hearing aid user	0.6	0.7	1.5	1.2	-0.6	0.7	0.6	1.0	0.7	1.1	0.6	0.3	0.7	1.0	0.8	0.9	0.5	0.6	1.1
Medication: Bendroflumethiazide	0.6	1.0	3.4	-1.9	-0.5	-1.1	-1.5	-0.8	-0.3	-0.5	-0.6	-0.9	-1.0	-0.5	-1.1	-0.9	-0.7	-1.0	-1.1
Commuting to job workplace: Cycle	0.6	0.7	3.2	0.3	-1.8	-0.9	-1.6	-0.6	-1.1	-0.2	-0.3	-1.3	-0.6	0.0	0.0	-0.5	-0.7	-0.6	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	2.9	1.4	1.7	0.6	0.5	0.6	0.8	0.4	0.7	1.4	0.6	0.9	0.9	0.6	0.4	0.8	0.4
Bipolar Disorder (2018)	0.5	0.8	3.5	-1.1	-0.9	-0.5	-1.9	-1.2	-0.8	-0.6	0.5	-1.0	-0.9	0.1	-0.3	-0.7	-0.2	-0.6	-0.9
Neuroticism (2016)	0.5	0.7	1.9	0.4	-0.3	-1.2	-0.8	-0.8	-0.3	-1.3	-0.2	0.5	-0.6	-0.2	-1.4	-1.2	-1.4	-0.4	-0.9
Rheumatoid Arthritis	0.5	0.7	1.4	0.3	0.9	1.2	1.0	0.6	0.2	0.9	1.2	-0.4	0.4	1.1	1.1	0.8	1.0	0.8	0.9
Diabetes (father)	0.5	0.6	2.9	-1.7	0.2	-0.4	-0.0	-0.4	-0.6	-0.0	0.1	-1.3	-0.7	-0.4	-1.0	-0.8	-0.2	-0.9	-1.3
Diabetes (self-reported)	0.5	0.8	2.5	-1.4	-0.3	-1.1	0.3	-0.8	-0.5	-0.5	-1.2	-1.6	-1.0	-0.3	-0.8	-0.9	-0.3	-0.9	-1.2
Standing height	0.5	5.1	13.5	1.6	2.0	2.4	2.5	3.1	3.7	2.2	0.8	1.6	2.9	1.4	1.5	2.5	2.4	2.0	2.1
Number of full sisters	0.5	0.6	1.9	0.3	-1.1	-0.2	-1.0	-0.7	-0.6	0.1	1.2	-0.2	-0.3	1.1	1.4	0.4	0.2	0.6	0.8
Suffer from ‘nerves’	0.5	0.7	2.9	-0.0	-0.6	-1.4	-0.9	-0.8	-0.4	-1.0	-1.7	0.1	-0.5	-1.0	-0.4	-0.8	-1.1	-0.6	-0.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.4	-1.2	-0.1	-1.0	-0.7	-0.5	-0.7	-0.8	-0.7	0.2	-0.6	-0.8	-1.1	-0.8	-0.7	-0.9	-1.2
Medication: Gliclazide	0.5	0.6	1.7	-0.9	-1.1	-0.7	-0.1	-1.3	-0.1	-0.7	-0.8	-1.3	-1.0	-0.7	-0.4	-0.7	-0.4	-0.4	-0.3
Medication: Paracetamol	0.5	0.8	2.2	-1.5	-1.1	-0.9	-1.3	-1.0	-1.1	0.1	0.1	-1.0	-0.9	-0.1	-0.3	-0.7	-0.7	-0.8	-1.0
Myopia	0.5	0.8	2.2	1.0	1.2	0.8	0.8	0.7	1.0	1.0	-0.4	1.5	0.9	0.1	0.7	0.7	0.7	0.9	0.8
Ulcerative Colitis (UC)	0.4	0.8	2.9	1.0	1.3	0.4	1.1	0.9	0.6	0.7	0.4	1.7	1.1	0.5	0.6	0.8	0.6	1.0	0.7
Mean Putamen Volume	0.4	0.5	1.5	-0.7	0.3	-1.1	-0.9	-0.4	-0.3	-0.6	-1.2	-0.8	-0.4	-0.8	-0.2	-0.5	-1.0	-0.4	-0.5
Triglycerides	0.4	0.6	1.7	-0.2	0.6	0.9	1.3	0.7	-0.2	0.5	0.6	0.9	0.7	1.1	0.8	0.9	0.9	0.9	0.9
Height	0.4	7.8	16.3	1.4	3.4	3.4	4.0	3.9	3.9	2.3	0.5	1.3	3.4	0.6	1.8	3.1	3.0	2.3	2.8
Tanning	0.4	4.3	8.2	1.8	1.9	2.1	1.6	2.1	1.5	2.9	2.1	1.0	2.0	2.3	2.7	2.3	2.3	1.9	1.8
Number of treatments/medications taken	0.4	0.7	1.6	-1.2	-0.0	-1.1	-0.6	-0.7	-0.5	-0.7	-0.7	-1.1	-1.0	-0.5	-0.5	-0.9	-0.7	-0.8	-1.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.3	1.0	0.6	0.4	1.0	0.3	0.4	0.3	1.0	1.1	0.5	0.4	0.7	0.6	0.4	0.8	0.8
Past tobacco smoking	0.4	0.7	1.5	-0.2	-1.2	-0.9	-0.9	-0.7	-0.8	-1.2	-0.7	-0.4	-0.7	-0.9	-1.0	-0.8	-1.2	-0.8	-0.4
Medication: Simvastatin	0.4	0.6	1.6	-0.8	0.6	-0.6	0.1	-0.7	-0.2	-0.9	-1.3	-0.6	-0.8	-1.1	-0.6	-0.8	-0.5	-0.9	-1.1
Time employed in main current job	0.4	0.5	1.7	-0.3	-0.0	-0.3	-0.5	-0.2	-0.7	-0.8	-0.6	-0.3	-0.6	-1.2	-1.3	-0.8	-1.0	-0.9	-0.6
Father’s age at death	0.4	0.5	2.5	0.5	-1.0	0.1	0.7	-0.6	-0.5	0.3	0.5	-0.2	-0.4	0.3	1.6	0.6	0.1	0.7	1.4
Gout (self-reported)	0.4	0.5	1.3	-0.7	0.2	-0.8	-1.2	-0.5	-1.1	-0.4	-0.6	0.1	-0.4	-0.4	-0.5	-0.7	-0.8	-0.8	-1.0
High blood pressure (siblings)	0.4	0.6	3.1	-0.4	-1.1	0.6	-0.2	0.2	-0.6	0.9	1.0	-0.6	-0.1	1.7	0.5	0.5	1.0	0.2	0.1
Wheeze or whistling in the chest in last year	0.4	0.7	2.8	1.3	1.1	-0.0	0.6	0.2	1.0	-0.3	-0.6	1.7	0.6	0.6	1.0	0.4	-0.2	1.2	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.0	-0.7	0.1	-0.7	-0.3	-0.3	0.3	-0.8	-1.0	-0.4	-0.2	-1.0	-0.8	-0.7	-0.9	-0.9	-0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.4	0.1	1.2	0.3	0.9	0.8	0.2	0.4	0.5	1.1	0.8	0.2	0.7	0.6	0.3	0.7	0.5
Illnesses of siblings: Diabetes	0.4	0.5	1.7	-0.5	-1.0	-1.3	-0.1	-0.9	-0.5	-0.9	-0.7	-0.1	-0.6	0.3	-0.5	-0.7	-1.1	-0.2	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.6	-0.3	-0.4	-0.9	-0.7	-0.7	-0.9	-1.6	-0.7	-0.2	-0.6	-0.6	-0.7	-0.8	-1.2	-0.6	-0.5
Smoking status: Current	0.4	0.7	3.2	0.5	-0.0	0.5	-0.2	0.1	0.4	1.0	1.8	0.1	0.2	1.3	1.2	0.7	0.8	1.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	4.3	-0.4	0.4	1.1	0.8	1.1	2.1	1.3	-0.0	-0.8	0.9	0.5	0.4	0.7	1.3	0.1	-0.2
High cholesterol (Self-reported)	0.4	0.6	1.5	-1.2	0.7	-0.8	-0.3	-0.8	-0.8	-0.8	-1.0	-1.0	-1.0	-0.7	-0.3	-0.8	-0.5	-0.7	-0.9
Medication: Lisinopril	0.4	0.5	1.7	-0.3	1.0	0.5	0.2	0.8	1.3	0.4	0.4	0.6	0.7	0.7	0.4	0.6	1.1	0.8	0.3
Cholesterol lowering medication	0.4	0.5	3.1	-0.2	0.2	-0.7	0.4	-0.3	-0.5	-0.6	-1.8	-0.6	-0.5	-1.6	0.1	-0.3	-0.6	-0.5	0.1
Schizophrenia vs Biploar Disorder	0.3	0.4	2.4	-0.1	-0.3	-0.7	0.5	-0.6	-0.4	0.1	-1.6	-0.5	-0.5	-1.0	-0.5	-0.5	-0.5	-0.8	-0.5
Respiratory disease	0.3	0.7	3.0	1.7	0.8	0.1	0.4	0.2	1.0	-0.3	-1.1	1.5	0.5	-0.7	0.9	0.3	-0.2	0.5	0.9
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.5	-0.0	-0.1	-0.7	-0.5	-0.2	0.4	-0.5	-1.2	-0.2	-0.5	-0.8	-0.8	-0.6	-0.5	-0.8	-0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.6	-0.8	-0.2	-0.4	-0.0	-0.5	-0.2	-0.6	-0.7	-0.6	-0.5	-0.6	-0.8	-0.5	-0.3	-0.7	-0.7
Angina	0.3	0.4	2.3	0.2	1.3	-0.4	1.5	-0.0	0.1	-0.0	-0.8	1.0	0.2	-0.4	0.5	0.2	0.2	0.3	0.2
Medication for hormone replacement therapy	0.3	0.4	1.9	0.3	1.3	-0.0	-0.1	0.5	0.6	0.7	-0.6	1.4	0.4	0.2	0.1	0.2	0.5	0.3	-0.3
Vitamin and mineral supplements	0.3	0.5	1.7	-1.3	-0.2	-0.6	-0.4	-1.1	-0.8	-0.5	-0.4	-0.5	-0.7	-0.5	-0.6	-0.7	-0.5	-0.5	-0.7
Current tobacco smoking	0.3	0.5	2.3	0.5	-0.1	0.4	0.1	0.2	0.4	0.8	1.5	-0.0	0.2	0.9	1.0	0.6	0.7	1.0	1.0
Taking other prescription medications	0.3	0.4	1.1	-0.9	0.2	-0.8	-0.4	-1.0	-0.5	-0.9	0.3	-0.2	-0.8	0.0	-0.4	-0.8	-0.7	-0.5	-1.0
Number of incorrect matches in round	0.3	0.5	2.0	1.4	0.5	-0.4	0.1	0.2	1.4	0.3	-0.3	1.4	0.5	0.5	0.1	0.1	0.1	0.5	-0.1
Forced vital capacity (FVC)	0.3	1.3	5.6	-0.3	0.2	1.0	2.1	1.3	2.4	1.0	-0.4	-0.7	1.2	-0.2	0.7	1.2	1.4	0.6	0.9
Mouth/teeth dental problems	0.3	0.5	3.2	-0.9	-0.6	0.2	-0.5	-0.4	-0.4	0.5	0.2	-1.8	-0.7	-1.1	-0.7	-0.5	-0.2	-0.7	-0.4
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.1	1.0	0.8	0.0	-1.0	-0.0	0.3	-0.2	-0.8	0.6	0.3	-0.6	0.5	0.0	-0.5	0.3	0.3
Number of full brothers	0.3	0.4	2.3	-1.0	-1.0	-0.3	-0.0	-0.7	-0.4	0.0	-0.2	-1.5	-0.7	-0.5	-0.0	-0.2	0.0	-0.5	-0.2
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.9	-0.0	0.7	-0.0	-0.5	-0.2	0.5	0.5	0.1	0.8	0.3	1.4	0.3	0.0	0.4	0.7	-0.4
Neck or shoulder pain in last month	0.3	0.4	1.0	0.8	0.5	0.3	0.6	0.6	0.5	0.5	0.4	1.0	0.6	1.0	0.5	0.5	0.5	0.5	0.2
Medication: Allopurinol	0.3	0.4	3.0	-0.1	1.7	0.4	0.2	0.7	0.0	0.8	0.3	0.5	0.6	0.7	0.8	0.5	0.3	0.4	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	1.9	-0.4	-0.8	-0.4	-0.4	-0.4	-0.7	-0.4	-1.4	-0.3	-0.5	-0.7	-0.4	-0.5	-0.6	-0.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.7	0.4	0.3	0.7	0.7	1.3	1.0	0.8	0.3	0.2	1.1	0.6	0.7	1.1	1.0	0.8	0.9
Average weekly red wine intake	0.3	0.5	1.9	0.1	1.1	1.0	-0.2	0.8	1.4	0.5	0.7	0.2	0.7	0.8	-0.1	0.3	0.8	0.2	-0.4
Qualifications: nursing, teaching	0.3	0.5	1.6	1.3	0.6	0.8	0.6	0.8	0.5	0.8	1.1	0.4	0.6	0.5	0.5	0.5	0.5	0.4	0.5
Mineral and other dietary supplements	0.3	0.5	2.0	-0.1	1.4	0.5	0.3	0.1	0.1	1.0	0.9	0.4	0.4	0.8	0.9	0.5	0.7	0.7	0.1
Osteoarthritis (self-reported)	0.3	0.4	1.6	-0.5	1.2	-0.5	1.3	0.1	-0.0	-0.4	-0.9	-0.0	0.0	-0.3	-0.3	-0.2	-0.1	-0.3	-0.8
Medication: Atorvastatin	0.3	0.3	1.3	-0.3	1.1	0.4	-0.3	0.6	0.2	0.7	0.8	-0.2	0.4	0.6	0.6	0.4	0.6	0.6	0.2
Risk taking	0.3	0.4	1.9	-0.0	-0.9	0.3	-1.0	-0.8	-0.9	-0.2	1.4	-0.7	-0.4	0.7	0.4	-0.1	-0.0	0.1	0.2
Age at First Birth	0.2	0.3	1.3	-0.0	-0.5	-0.7	-0.8	-0.3	-0.7	-1.1	-1.0	-0.1	-0.2	-0.5	-0.0	-0.2	-0.6	-0.0	0.1
Body Mass Index (BMI) (2010)	0.2	0.3	2.7	0.7	0.0	0.4	1.6	0.3	-0.0	-0.3	0.1	-0.3	-0.0	-0.1	0.3	0.3	-0.1	0.3	0.8
Lupus	0.2	0.3	1.2	0.2	0.8	0.3	0.6	0.5	1.1	-0.2	-0.1	0.4	0.8	-0.6	0.3	0.4	-0.1	0.4	0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	0.7	0.5	-0.7	-0.6	-0.4	-0.5	-0.2	-0.9	-0.1	-0.8	-0.4	-0.3	0.3	-0.4	-0.4	-0.2	-0.0
Supplements: Zinc	0.2	0.2	1.5	1.2	0.0	0.1	-0.3	-0.1	0.5	-0.6	-0.2	0.6	0.2	-0.3	-0.2	-0.2	-0.4	-0.1	-0.1
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.4	-0.8	-0.1	-0.4	0.5	-0.4	-0.8	-0.6	-0.3	-0.5	-0.6	-1.5	-0.6	-0.6	-0.7	-0.8	-0.4
Had menopause	0.2	0.2	1.6	0.2	0.3	-0.6	0.0	-0.1	0.4	-0.5	-1.2	0.3	-0.1	-1.0	0.2	-0.0	-0.3	-0.2	0.1
Financial difficulties in last 2 years	0.2	0.2	1.4	-0.5	0.3	-0.6	-1.2	-0.3	0.2	0.4	-0.6	-0.4	-0.4	0.4	0.0	-0.3	0.2	-0.0	-0.7
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.9	0.3	-0.3	0.3	0.6	-0.2	0.7	-0.1	0.6	-0.3	0.1	-0.0	0.8	0.4	0.1	0.6	1.0
Number of live births	0.2	0.3	2.7	0.1	-0.0	-0.9	-0.1	-0.1	-0.0	-0.4	-1.6	-0.0	-0.0	-0.8	-0.0	-0.2	-0.2	-0.1	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	2.6	-0.2	-0.3	1.0	0.4	0.7	0.3	0.8	1.6	-0.3	0.3	0.4	-0.0	0.4	0.5	0.1	0.2
Asthma	0.2	0.3	0.9	0.9	-0.0	-0.2	-0.3	-0.4	-0.1	-0.9	-1.0	0.7	0.0	-0.6	0.7	0.0	-0.6	0.2	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.8	-0.4	0.9	0.5	-0.4	0.6	0.3	-0.2	0.4	0.4	0.1	-0.2	-0.8	-0.2	0.0	-0.2	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.4	-0.7	-0.2	-0.4	-1.2	-0.9	-0.4	0.2	0.2	-0.5	-0.9	0.0	-0.1	-0.6	0.0	-0.5	-0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.6	-0.1	0.3	-0.7	-0.3	-0.8	-0.7	-0.4	-0.2	0.1	-0.5	-0.2	-0.5	-0.5	-0.4	-0.4	-0.7
Loud music exposure frequency	0.2	0.3	1.1	-0.2	-0.4	0.9	-0.1	0.1	-0.3	1.0	0.3	-0.1	0.1	0.2	0.7	0.6	0.7	0.3	0.7
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.8	0.2	0.8	0.2	0.9	0.9	-0.4	-0.1	0.7	0.7	0.6	0.5	0.1	0.5	0.3	0.4	0.3
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.4	1.2	-1.0	-0.1	-0.2	0.0	0.1	-0.7	-0.4	0.6	0.3	-1.0	0.0	0.1	-1.0	-0.0	1.0
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.7	-0.0	0.6	-0.2	-0.1	-0.8	-0.5	-0.6	-0.7	-0.1	-0.5	-0.3	-0.1	-0.5	-0.5	-0.3	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.6	2.9	-1.3	-0.0	0.3	0.8	0.8	1.7	0.3	-0.7	-1.3	0.6	-0.9	-0.1	0.4	0.5	-0.4	-0.1
Exposure to tobacco smoke outside home	0.2	0.2	0.7	0.2	0.6	-0.6	-0.2	0.0	0.3	0.0	-0.8	0.5	-0.2	-0.4	-0.6	-0.4	-0.1	-0.6	-0.8
Number of children fathered	0.2	0.2	1.6	0.3	0.1	-0.1	-0.3	0.2	0.4	-0.1	0.2	0.5	0.4	1.3	0.3	0.1	-0.0	0.3	-0.1
Angina (self-reported)	0.2	0.3	2.1	0.1	1.0	-0.4	1.5	0.0	-0.1	0.1	-0.9	0.7	0.1	-0.4	0.3	0.1	0.3	0.2	0.1
Medication: Ibuprofen	0.2	0.2	1.4	0.1	1.2	0.4	-0.4	0.6	0.4	-0.3	0.5	0.8	0.4	0.2	-0.3	0.1	0.1	0.3	-0.2
Medication: Seretide 50 evohaler	0.2	0.2	0.8	-0.1	0.4	0.3	0.6	-0.1	0.3	-0.1	0.0	0.3	0.2	-0.1	0.9	0.5	0.2	0.5	0.8
Mean time to correctly identify matches	0.2	0.3	1.3	0.3	1.1	-0.0	0.9	0.4	0.5	0.4	0.5	0.6	0.4	0.8	0.4	0.4	0.9	0.5	-0.0
Alcohol intake frequency.	0.2	0.4	1.7	-0.9	-0.5	-0.6	0.5	-0.7	-0.6	-1.1	-1.3	-0.6	-0.5	-0.7	0.0	-0.3	-0.5	-0.4	0.1
Breast cancer (self-reported)	0.2	0.3	1.7	0.1	-0.2	0.6	0.3	0.6	0.5	0.7	0.2	-1.3	0.3	0.0	0.1	0.3	0.6	0.3	0.5
Asthma (self-reported)	0.2	0.4	1.6	0.9	-0.0	-0.3	-0.2	-0.5	0.1	-0.9	-1.3	0.7	0.0	-0.8	0.7	-0.0	-0.6	0.2	0.7
Medication: Aspirin	0.2	0.3	1.0	0.7	0.8	0.2	0.4	0.1	0.5	0.6	-0.2	0.1	0.2	0.4	1.0	0.5	0.6	0.5	0.5
Arm fat mass (left)	0.2	0.8	1.8	-0.9	-0.2	-1.1	-1.4	-1.3	-0.5	-1.1	-0.8	-0.3	-0.9	-0.8	-0.4	-1.0	-0.7	-0.8	-1.1
Illnesses of father: High blood pressure	0.2	0.3	1.1	-1.0	0.6	0.3	-0.1	0.1	-0.9	0.0	0.9	-0.7	-0.2	0.4	-0.2	-0.1	0.2	-0.2	-0.3
Average weekly beer plus cider intake	0.2	0.3	1.1	-0.1	0.3	-0.9	-0.5	-0.8	-0.0	-1.0	-0.2	0.3	-0.3	0.1	-0.3	-0.6	-0.7	-0.4	-0.6
Pain experienced in last month	0.2	0.4	1.6	-0.1	-0.1	0.8	0.7	0.2	1.0	-0.3	0.0	-0.8	0.3	-0.7	0.5	0.5	0.1	0.6	1.3
Alcohol drinker status: Previous	0.2	0.3	1.0	0.5	0.8	-0.0	-0.6	0.6	0.6	0.1	-0.1	1.0	0.8	0.3	0.4	0.4	-0.1	0.3	0.4
Major Depression (MDD)	0.1	0.2	1.0	1.0	0.1	0.1	-0.5	-0.0	0.3	-0.1	0.2	0.5	0.3	-0.2	0.3	0.2	-0.1	0.5	0.7
Reaction Time	0.1	0.2	1.1	0.0	1.0	-0.4	0.4	0.5	0.6	-0.3	0.3	0.6	0.4	0.1	-0.1	0.1	0.2	0.1	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.5	-0.5	0.3	0.3	-0.3	-0.1	-0.3	0.7	0.6	-0.2	-0.2	0.4	0.1	-0.2	0.1	-0.2	-0.4
Breast Cancer	0.1	0.2	1.2	0.6	0.8	-0.1	0.0	-0.2	-0.4	-0.2	-0.3	1.1	0.1	0.4	-0.1	-0.1	-0.3	0.2	-0.1
Ulcerative Colitis	0.1	0.2	1.0	0.2	0.6	0.1	0.7	0.2	0.4	1.0	0.1	0.2	0.2	0.4	0.3	0.3	0.7	0.5	0.1
Blood Eosinophil Count	0.1	0.5	1.6	-0.8	1.3	-0.5	0.2	-0.9	-0.9	-0.8	-0.6	-0.3	-0.7	-0.9	-0.5	-0.8	-0.5	-0.3	-0.9
Allergy or Eczema	0.1	0.2	0.8	0.1	0.9	0.2	0.3	0.4	-0.2	-0.3	0.4	0.7	0.2	-0.8	-0.4	-0.1	-0.3	-0.1	-0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	1.3	-0.6	-0.3	-0.5	1.1	-0.3	-0.0	0.1	-0.4	-0.7	-0.3	-0.1	0.1	-0.1	0.1	0.1	0.2
Lung FVC	0.1	0.5	3.2	-0.7	-1.4	-0.1	0.3	-0.4	0.1	-0.2	-0.6	-1.8	-0.5	-0.8	-0.1	-0.2	0.1	-0.6	-0.3
Hearing difficulty/problems: Yes	0.1	0.2	0.6	-0.7	-0.4	-0.2	0.6	-0.5	-0.2	0.8	-0.2	-0.8	-0.4	0.1	0.2	-0.0	0.5	-0.2	-0.2
Medication: Co-codamol	0.1	0.1	1.1	0.1	0.6	0.1	0.2	0.2	-0.1	0.0	1.1	0.2	0.2	0.5	0.2	0.0	-0.0	0.3	-0.0
Average weekly fortified wine intake	0.1	0.1	0.3	-0.3	-0.2	0.1	0.2	0.4	0.5	0.4	-0.1	-0.5	0.2	0.2	0.6	0.3	0.5	0.3	0.3
Relative age voice broke	0.1	0.2	0.8	-0.4	0.3	-0.2	0.4	-0.1	-0.9	-0.2	0.4	-0.2	-0.4	-0.2	-0.6	-0.4	-0.4	-0.5	-0.7
Qualifications: CSEs or equivalent	0.1	0.2	0.8	0.3	0.6	-0.4	0.3	-0.3	-0.9	-0.5	-0.6	0.2	0.0	-0.4	0.2	-0.1	-0.5	0.2	0.3
Serious illness, injury or assault to yourself	0.1	0.2	0.7	-0.3	-0.6	-0.4	-0.5	-0.8	-0.3	0.2	0.0	-0.6	-0.5	0.4	0.6	-0.1	-0.1	0.0	0.0
Chronic bronchitis/emphysema (father)	0.1	0.2	0.7	0.8	0.3	0.5	0.6	0.0	0.2	0.3	0.2	0.8	0.3	0.1	0.2	0.3	0.2	0.3	0.4
Alcohol usually taken with meals	0.1	0.2	0.7	0.2	-0.5	0.1	-0.1	0.0	0.5	0.5	0.3	-0.7	0.1	0.4	0.8	0.4	0.4	0.4	0.5
Allergy	0.1	0.1	0.9	0.0	-0.4	0.1	-0.5	-0.0	-0.0	0.3	0.1	-0.5	0.0	0.9	-0.2	0.0	0.4	0.0	-0.3
Fluid intelligence score	0.1	0.2	0.5	-0.5	-0.2	-0.0	-0.5	-0.2	-0.0	0.1	0.4	-0.7	-0.3	-0.3	-0.2	-0.4	-0.2	-0.7	-0.6
Weight	0.1	0.6	2.7	1.0	0.9	0.4	0.4	0.7	1.6	0.3	-0.2	1.1	1.0	0.3	0.9	0.7	0.8	0.7	0.5
Alcohol intake versus 10 years previously	0.1	0.2	1.3	0.4	0.4	-0.0	1.1	0.3	-0.2	-0.5	0.5	0.4	0.2	-0.3	-0.2	-0.1	-0.2	-0.0	0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.4	0.0	0.5	-0.2	-0.5	0.3	-0.2	-0.6	-0.1	0.3	0.3	-0.2	-0.2	0.1	-0.0	0.1	-0.0
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.2	0.9	-0.0	0.9	0.5	0.3	0.4	0.3	0.3	-0.3	0.5	0.3	-0.1	0.2	0.3	0.2	0.4	0.4
Depression (self-reported)	0.1	0.1	0.5	-0.1	-0.1	-0.3	-0.7	-0.6	0.3	0.4	0.1	-0.6	-0.6	0.1	0.5	-0.2	0.1	-0.0	-0.2
Arm fat mass (right)	0.1	0.4	1.3	-0.6	-0.0	-0.9	-1.1	-1.1	-0.2	-0.8	-0.5	-0.1	-0.7	-0.3	-0.1	-0.7	-0.4	-0.5	-0.9
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.2	-0.1	0.3	0.6	0.0	0.4	-0.6	0.3	1.1	-0.2	0.1	0.6	-0.6	0.0	0.2	-0.0	-0.3
Glaucoma (self-reported)	0.1	0.1	0.6	0.8	0.4	-0.0	0.1	0.1	0.3	-0.5	-0.3	0.6	0.1	0.2	0.1	-0.1	-0.5	0.3	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	0.5	0.5	-0.2	-0.3	-0.6	0.4	0.4	-0.7	-0.4	-0.0	0.2	-0.0	-0.6	-0.2	-0.0	-0.4	-0.5
Health satisfaction	0.1	0.2	0.5	-0.6	-0.2	-0.5	-0.5	-0.5	-0.7	-0.2	-0.0	-0.2	-0.5	0.0	-0.1	-0.5	-0.5	-0.3	-0.4
Shortness of breath walking on level ground	0.1	0.1	0.5	0.1	-0.4	-0.5	-0.5	-0.2	-0.5	-0.3	0.6	0.3	-0.1	0.3	0.7	0.1	-0.2	0.2	0.3
Medication: Aspirin	0.1	0.1	0.5	0.3	0.6	0.0	0.6	-0.1	0.2	0.4	-0.4	-0.2	0.0	0.2	0.7	0.3	0.5	0.3	0.3
Smoking status: Previous	0.1	0.1	0.7	-0.1	0.6	0.1	0.8	0.3	0.4	0.1	-0.8	0.2	0.3	-0.2	-0.0	0.1	0.3	0.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.4	-0.4	0.2	0.4	0.5	0.1	0.3	0.7	-0.2	-0.1	0.1	-0.2	0.2	0.3	0.6	0.0	0.1
Wears glasses or contact lenses	0.1	0.1	0.5	-0.2	-0.0	-0.2	-0.5	-0.3	0.0	0.2	-0.7	-0.1	-0.4	-0.5	0.5	-0.0	-0.1	-0.2	-0.1
Ever taken oral contraceptive pill	0.1	0.1	0.2	-0.0	0.3	0.3	0.2	0.5	0.2	0.4	0.3	-0.4	0.1	-0.2	-0.2	0.1	0.2	-0.1	0.1
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	0.5	0.5	0.4	0.2	0.4	-0.1	0.2	-0.1	0.1	0.4	0.2	0.2	0.3	0.3	-0.0	0.0
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.3	0.1	-0.5	0.0	0.3	0.4	-0.2	-0.4	0.1	-0.3	-0.1	-0.2	-0.5	-0.0	-0.2	-0.1	0.3
Fractured/broken bones in last 5 years	0.1	0.1	0.7	-0.0	-0.4	-0.0	0.4	-0.2	-0.0	0.1	-0.1	-0.7	-0.1	-0.1	0.5	0.3	0.1	0.5	0.8
Unable to work because of sickness or disability	0.1	0.1	0.6	0.4	0.4	-0.4	0.2	0.5	-0.3	0.3	0.4	0.4	0.4	0.8	0.1	0.1	0.3	0.3	-0.3
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.4	0.2	0.1	0.3	-0.1	-0.0	0.3	0.4	0.6	0.4	0.1	0.3	-0.0	-0.1	0.2	-0.0	-0.2
BMI	0.0	0.1	0.3	0.6	0.1	-0.4	-0.4	-0.2	0.2	-0.4	-0.3	0.4	-0.1	-0.1	0.1	-0.3	0.0	-0.2	-0.5
Chronotype (morning person)	0.0	0.1	0.6	0.0	-0.4	-0.3	-0.3	-0.1	-0.4	-0.2	-0.8	-0.1	-0.3	0.0	-0.2	-0.2	0.0	-0.3	-0.2
Hair Pigment	0.0	0.5	1.4	-1.0	-1.2	-0.8	0.1	-0.9	-0.5	-0.3	-0.8	-0.5	-0.5	-0.8	-0.7	-0.7	-0.6	-0.6	-0.6
Body mass index (BMI)	0.0	0.1	0.4	0.4	0.2	-0.5	-0.4	-0.5	0.2	-0.4	-0.3	0.6	-0.1	-0.1	0.5	-0.2	-0.0	-0.0	-0.2

Hub : Genes

HELLS

Models

Trait associations