TWAS hub - TBC1D12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Cervical Squamous Cell Carcinoma	0.0430	0.0290	0.00700	0.012	0.034	0.015	NA	0.005	7.9e-02	0.00830	0.0560	NA	0.1800
2	TCGA	Prostate Adenocarcinoma	0.0351	0.0224	0.00046	0.039	0.030	0.022	NA	0.025	5.9e-05	0.00039	0.0022	NA	0.0011

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Systolic Blood Pressure	14.8	74.1	84.3	8.0	-9.2
Blood White Count	13.7	101.4	110.2	9.6	-10.5
Birth weight of first child	13.0	23.6	25.6	-5.1	4.7
Impedance of leg (left)	10.6	51.5	59.1	6.6	-7.7
Impedance of leg (right)	10.4	50.2	58.1	6.5	-7.6
Medication: Atenolol	9.8	12.2	12.8	3.4	-3.6
Impedance of whole body	8.7	44.2	52.4	6.0	-7.2
Systolic blood pressure, automated reading	8.6	25.1	28.4	4.7	-5.3
Headache pain in last month	8.3	14.3	14.6	3.7	-3.8
Osteoporosis (self-reported)	7.9	9.8	10.9	3.3	-2.9
Leg fat percentage (right)	7.6	27.5	29.5	5.0	-5.4
Medication: Amlodipine	7.5	10.5	13.0	2.8	-3.6
Supplements: Calcium	7.2	8.0	8.4	2.9	-2.7
Number of self-reported non-cancer illnesses	6.9	11.9	12.5	3.4	-3.5
Leg fat percentage (left)	6.9	24.9	26.6	4.8	-5.2
Birth weight	6.5	14.1	14.6	-3.7	3.8
Cardiovascular Disease	6.2	20.6	25.5	4.0	-5.0
Impedance of arm (right)	6.2	28.8	34.4	4.8	-5.9
Hypertension (Self-reported)	6.2	17.1	21.4	3.6	-4.6
High blood pressure (mother)	6.1	8.5	9.6	2.7	-3.1
Impedance of arm (left)	6.1	28.0	33.5	4.8	-5.8
High blood pressure	6.0	16.7	21.2	3.5	-4.6
Blood Red Count	5.9	56.7	59.4	7.7	-7.3
Body fat percentage	5.8	23.1	25.2	4.6	-5.0
Trunk fat-free mass	5.2	29.9	33.1	-5.2	5.8
Whole body fat-free mass	5.1	29.1	32.1	-5.1	5.7
Trunk fat percentage	5.0	19.9	22.0	4.2	-4.7
Frequency of tenseness / restlessness in last 2 weeks	5.0	7.7	7.8	2.8	-2.8
Trunk predicted mass	5.0	28.7	31.9	-5.0	5.7
Whole body water mass	4.9	28.1	31.4	-5.0	5.6
Pack years of smoking	4.9	7.2	7.6	2.6	-2.8
Leg predicted mass (right)	4.6	24.6	27.0	-4.7	5.2
Leg fat-free mass (right)	4.5	24.1	26.5	-4.7	5.2
Vascular/heart problems diagnosed by doctor	4.3	11.6	15.0	-2.9	3.9
Severe depression (siblings)	4.1	4.6	5.2	2.0	-2.3
Sitting height	4.0	28.5	30.8	-5.5	5.1
Heart disease (mother)	4.0	4.8	5.4	2.1	-2.3
Migraine (self-reported)	3.9	4.8	5.8	2.0	-2.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.9	4.5	4.6	2.1	-2.1
Diastolic blood pressure, automated reading	3.9	12.0	15.4	2.9	-3.9
Happiness	3.8	4.6	4.7	2.2	-2.1
Peak expiratory flow (PEF)	3.8	8.8	10.0	-3.2	2.8
Coronary Artery Disease (CAD)	3.7	4.4	4.5	-2.1	2.1
Pack years adult smoking proportion	3.7	5.7	5.8	2.3	-2.4
Leg fat-free mass (left)	3.7	19.6	21.4	-4.2	4.6
Medication: Levothyroxine sodium	3.6	6.1	6.9	-2.3	2.6
Leg predicted mass (left)	3.6	19.3	21.1	-4.2	4.6
Medication: Blood pressure	3.6	6.8	7.2	2.5	-2.7
Bipolar Disorder or Schizophrenia	3.5	8.5	10.2	2.6	-3.2
Townsend deprivation index at recruitment	3.5	4.9	5.7	2.0	-2.4
Arm fat-free mass (right)	3.5	18.1	20.6	-4.0	4.5
Arm predicted mass (right)	3.5	17.7	20.0	-3.9	4.5
Lung FEV1/FVC ratio	3.4	17.3	21.8	-4.7	3.6
Friendships satisfaction	3.4	4.2	4.6	2.0	-2.1
Prospective memory result	3.3	4.1	4.8	-2.2	1.8
Arm predicted mass (left)	3.3	16.8	19.2	-3.8	4.4
Schizophrenia (2018)	3.2	6.6	8.4	2.2	-2.9
Illnesses of mother	3.2	4.0	4.9	-1.8	2.2
Blood clot in the leg (DVT)	3.2	4.1	4.7	-2.2	1.9
Blood Platelet Count	3.1	36.5	37.1	6.1	-6.0
Hair/balding pattern: Pattern 4	3.1	7.4	7.5	-2.7	2.7
Basal metabolic rate	3.1	17.4	19.4	-3.9	4.4
Basal cell carcinoma (self-reported)	2.8	3.3	3.8	1.7	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	2.7	3.6	4.0	1.8	-2.0
Frequency of tiredness / lethargy in last 2 weeks	2.7	4.3	4.4	2.1	-2.1
Seen a psychiatrist for nerves, anxiety, tension or depression	2.7	3.6	3.8	1.8	-1.9
Arm fat percentage (left)	2.7	10.9	11.4	3.2	-3.4
Arm fat-free mass (left)	2.7	13.8	15.9	-3.4	4.0
Bilateral oophorectomy (both ovaries removed)	2.6	3.1	3.5	-1.6	1.9
Falls in the last year	2.6	3.5	4.1	1.7	-2.0
Illnesses of father: Heart disease	2.6	3.7	4.2	-2.0	1.8
Hand grip strength (left)	2.5	6.5	7.7	-2.3	2.8
Frequency of depressed mood in last 2 weeks	2.5	3.5	3.9	2.0	-1.8
Noisy workplace	2.5	3.1	3.4	-1.7	1.9
Long-standing illness, disability or infirmity	2.5	3.8	3.9	1.9	-2.0
Depressed Affect (Nagel 2018)	2.4	5.1	6.0	2.4	-2.0
Medication: Paracetamol	2.4	4.0	4.8	1.8	-2.2
Medication for pain relief, constipation, heartburn	2.4	4.1	5.0	-1.8	2.2
Back pain experienced in last month	2.4	3.6	3.6	1.9	-1.9
Deep venous thrombosis (DVT) (self-reported)	2.4	3.1	3.6	-1.9	1.6
Tense / ‘highly strung’	2.3	3.8	4.1	2.0	-1.9
Financial situation satisfaction	2.3	2.8	3.5	1.5	-1.9
Stomach or abdominal pain in last month	2.2	2.8	2.9	1.7	-1.6
Arm fat percentage (right)	2.2	8.8	9.3	2.9	-3.1
Medication: Blood pressure	2.2	3.9	5.7	1.5	-2.4
Miserableness	2.2	3.7	3.9	2.0	-1.9
Depression (Nagel 2018)	2.1	3.2	3.7	1.9	-1.6
Alzheimer’s Disease (in mother)	2.1	2.5	2.5	-1.6	1.6
Pulse wave reflection index	2.1	2.5	3.1	1.4	-1.8
Crohns Disease (2017)	2.0	4.4	4.8	-2.2	2.0
Schizophrenia (2014)	2.0	4.3	5.5	1.8	-2.3
Waist Hip Ratio (WHR)	2.0	8.8	9.5	3.1	-2.9
Hair/balding pattern: Pattern 2	2.0	2.5	3.3	1.8	-1.3
Pulse rate, automated reading	2.0	6.3	6.7	-2.4	2.6
Commuting to job workplace: Walk	2.0	2.2	2.7	1.3	-1.6
Alzheimer’s Disease (including proxy)	1.9	2.8	2.9	-1.7	1.6
Hypothyroidism (self reported)	1.9	4.3	4.4	-2.0	2.1
Sensitivity / hurt feelings	1.9	3.3	3.8	-1.7	1.9
Hand grip strength (right)	1.9	5.0	6.0	-2.0	2.4
Age when periods started (menarche)	1.9	4.5	4.9	-2.2	2.0
Length of working week for main job	1.9	2.1	2.4	-1.3	1.5
Leg fat mass (right)	1.9	7.5	7.9	2.7	-2.8
Crohns Disease (2012)	1.8	2.9	3.6	-1.9	1.5
Trunk fat mass	1.8	7.5	8.4	2.6	-2.9
Medication for cholesterol	1.8	2.7	2.8	-1.6	1.7
Alcohol drinker status: Never	1.8	2.2	2.6	1.6	-1.4
Ovarian Cancer	1.7	2.2	2.5	1.4	-1.6
Prostate Cancer	1.7	2.4	2.6	-1.5	1.6
LDL Cholesterol	1.7	2.7	2.8	-1.7	1.6
Ever had hysterectomy (womb removed)	1.7	1.9	2.5	1.6	-1.2
Waist circumference	1.7	6.4	7.3	2.7	-2.3
Forced expiratory volume in 1-second (FEV1)	1.7	5.6	7.1	-2.7	2.0
Hypothyroidism/myxoedema (self-reported)	1.7	3.4	3.6	-1.8	1.9
Qualifications: College or University degree	1.7	5.4	5.9	2.2	-2.4
Eye problems/disorders: None of the above	1.7	2.0	2.2	-1.3	1.5
Leg pain on walking	1.7	2.1	2.3	-1.5	1.4
Supplements: Vitamin C	1.7	2.0	2.7	-1.2	1.6
HbA1C	1.6	1.7	2.0	-1.4	1.2
Pulse rate	1.6	2.7	3.3	-1.5	1.8
Exposure to tobacco smoke at home	1.6	1.8	1.9	1.3	-1.4
Family relationship satisfaction	1.6	2.0	2.1	1.4	-1.4
Irritability	1.6	2.7	2.7	1.6	-1.6
Neuroticism	1.5	3.5	3.9	2.0	-1.8
Hearing difficulty/problems with background noise	1.5	2.3	3.2	1.2	-1.8
Whole body fat mass	1.5	6.1	6.7	2.4	-2.6
Age started oral contraceptive pill	1.5	1.9	2.2	-1.5	1.3
Leg fat mass (left)	1.5	5.7	6.0	2.3	-2.5
Irritable Bowel Disease (IBD)	1.4	3.4	3.4	-1.8	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.5	6.1	-2.5	1.7
Loneliness, isolation	1.4	1.9	2.0	1.4	-1.4
Eye problems/disorders: Cataract	1.4	1.6	1.8	1.2	-1.3
Ever depressed for a whole week	1.4	1.7	1.9	1.4	-1.2
Bipolar Disorder (2018)	1.3	2.1	2.2	1.4	-1.5
Number of treatments/medications taken	1.3	2.3	2.7	1.4	-1.6
Supplements: Glucosamine	1.3	1.7	1.7	-1.3	1.3
Overall health rating	1.3	2.9	3.4	1.8	-1.5
Mood swings	1.3	2.4	2.6	1.6	-1.5
Medication: Paracetamol	1.2	1.9	2.5	1.2	-1.6
Height	1.1	21.7	23.4	-4.8	4.5
Standing height	1.1	10.6	11.6	-3.4	3.1
Medication: Bendroflumethiazide	1.1	1.6	2.1	1.1	-1.5
HDL Cholesterol	1.0	1.7	1.9	-1.4	1.2
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	1.2	1.1	-1.1
Heart attack	1.0	1.3	1.4	-1.1	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	1.8	1.1	-1.3
Worry too long after embarrassment	1.0	1.7	1.7	1.3	-1.3
Guilty feelings	1.0	1.5	1.7	1.2	-1.3
Mother’s age at death	1.0	1.2	1.3	-1.1	1.1
Heart disease (siblings)	1.0	1.2	1.3	-1.1	1.0
Neuroticism (Nagel 2018)	0.9	2.2	2.8	1.7	-1.3
Type 2 Diabetes (T2D) (2012)	0.9	1.1	1.4	0.8	-1.2
Medication: Metformin	0.9	1.3	1.6	1.3	-1.0
Diabetes (mother)	0.9	1.2	1.3	-1.1	1.1
Taking other prescription medications	0.9	1.4	1.4	1.2	-1.2
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.3	1.1	-0.9
Diabetes (self-reported)	0.9	1.4	1.8	1.0	-1.3
Medication: Ramipril	0.9	1.2	1.5	0.9	-1.2
Neuroticism score	0.9	1.9	2.2	1.5	-1.2
Comparative body size at age 10	0.9	2.5	3.0	-1.4	1.7
Age at first live birth	0.9	1.7	1.7	1.3	-1.3
Emphysema/chronic bronchitis	0.9	1.0	1.4	1.2	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	1.9	-1.4	1.3
Ever had prostate specific antigen (PSA) test	0.9	1.1	1.3	-1.1	0.9
Fasting Glucose	0.8	1.0	1.2	-1.1	0.9
Multivitamins +/- minerals	0.8	1.0	1.1	-1.0	1.0
Medication: Lansoprazole	0.8	0.9	1.1	-0.8	1.0
Pulse wave Arterial Stiffness index	0.8	1.0	1.3	-1.1	0.8
Chest pain or discomfort	0.8	1.2	1.8	1.4	-0.7
Had major operations	0.8	0.9	1.3	-0.7	1.2
Illnesses of siblings: Diabetes	0.8	1.0	1.2	1.1	-0.9
Diabetes diagnosed by doctor	0.8	1.2	1.4	1.0	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	1.1	1.1	-0.9
Medication: Gliclazide	0.8	0.9	1.0	1.0	-0.9
Commuting to job workplace: Cycle	0.8	1.0	1.0	1.0	-1.0
Ulcerative Colitis (UC)	0.7	1.2	1.4	-1.0	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	1.7	-1.3	1.1
Pain all over the body in last month	0.7	0.7	0.8	-0.8	0.9
Hip circumference	0.7	3.1	3.1	1.7	-1.8
Mouth/teeth dental problems: Dentures	0.7	1.2	1.4	-1.0	1.2
Depression (self-reported)	0.7	0.8	0.8	0.9	-0.9
Comparative height size at age 10	0.7	3.8	4.2	-2.0	1.9
Knee pain experienced in last month	0.7	1.0	1.6	-1.3	0.7
Hearing aid user	0.7	0.7	0.8	-0.8	0.9
Eye problems/disorders: Glaucoma	0.7	0.9	1.1	-0.8	1.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	1.0	-0.9	1.0
Worry (Nagel 2018)	0.6	1.2	1.5	1.2	-0.9
Relative age of first facial hair	0.6	1.2	1.3	-1.1	1.1
Serious illness, injury or assault to yourself	0.6	0.7	0.8	0.8	-0.9
Forced vital capacity (FVC)	0.6	2.3	2.7	-1.6	1.4
Financial difficulties in last 2 years	0.6	0.8	1.2	0.6	-1.1
Medication: Simvastatin	0.6	0.9	0.9	0.9	-1.0
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	0.8	-0.9	0.8
Suffer from ‘nerves’	0.6	1.0	1.3	1.1	-0.8
Pain type(s) experienced in last month: Hip pain	0.6	0.7	0.9	-0.8	0.9
High cholesterol (Self-reported)	0.6	1.1	1.2	1.0	-1.1
Pain experienced in last month	0.6	1.0	1.3	-0.8	1.1
Alcohol drinker status: Previous	0.6	0.6	0.8	-0.7	0.9
Alzheimer’s Disease (in father)	0.5	0.5	0.6	-0.7	0.8
Lupus	0.5	0.8	1.1	-0.7	1.1
Heel T-Score	0.5	4.4	4.7	-2.0	2.2
Vitamin and mineral supplements	0.5	0.7	0.7	0.8	-0.8
Diabetes (father)	0.5	0.6	1.0	0.5	-1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	1.7	-1.3	0.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.6	-0.5	1.3
Medication: Omeprazole	0.5	0.6	0.6	-0.7	0.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	0.7	-0.7	0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.9	0.9	-0.6
Average weekly champagne plus white wine intake	0.5	0.7	1.1	-1.0	0.7
Ever smoked	0.5	0.9	1.3	-1.2	0.7
Number of operations (self-reported)	0.5	0.8	1.1	-0.7	1.1
Neuroticism (2016)	0.4	0.5	0.8	0.9	-0.5
Rheumatoid Arthritis	0.4	0.5	0.6	-0.8	0.6
Smoking Status	0.4	0.8	1.1	-1.0	0.8
Hearing difficulty/problems: Yes	0.4	0.6	0.9	0.5	-0.9
Fed-up feelings	0.4	0.8	1.1	1.0	-0.7
Qualifications: None of the above	0.4	0.9	1.0	-0.9	1.0
Worrier / anxious feelings	0.4	0.8	0.9	1.0	-0.8
Number of full brothers	0.4	0.5	0.6	0.6	-0.7
Pulse wave peak to peak time	0.4	0.5	0.6	0.8	-0.5
Mouth/teeth dental problems: Loose teeth	0.4	0.5	0.6	0.6	-0.8
Arm fat mass (left)	0.4	1.8	1.9	1.4	-1.3
Ever taken oral contraceptive pill	0.4	0.5	0.6	-0.8	0.6
Myopia	0.4	0.6	0.7	-0.8	0.8
Schizophrenia vs Biploar Disorder	0.3	0.4	0.5	0.5	-0.7
Body Mass Index (BMI) (2010)	0.3	0.4	0.7	-0.4	0.8
Primary Biliary Cirrhosis	0.3	0.4	0.5	0.6	-0.7
Triglycerides	0.3	0.5	0.6	-0.7	0.8
Respiratory disease	0.3	0.6	1.2	-0.3	1.1
Tanning	0.3	3.4	4.0	-2.0	1.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.5	0.7	-0.4
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.4	-0.4	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.3	-0.6	0.5
Arm fat mass (right)	0.3	1.3	1.4	1.2	-1.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.4	0.7	-0.6
Gout (self-reported)	0.3	0.4	0.5	0.5	-0.7
Health satisfaction	0.3	0.4	0.5	0.7	-0.6
Number of full sisters	0.3	0.4	0.6	0.8	-0.5
Age at last live birth	0.3	0.5	0.6	0.8	-0.6
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.5	0.5	-0.7
Qualifications: nursing, teaching	0.3	0.5	0.6	-0.7	0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	0.7	0.8	-0.2
Risk taking	0.3	0.5	0.6	0.8	-0.6
Bipolar Disorder (2011)	0.2	0.2	0.4	-0.6	0.3
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.4	0.6	-0.5
Maternal smoking around birth	0.2	0.3	0.3	0.5	-0.5
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.8	-0.9	0.4
Medication: Cholesterol lowering	0.2	0.3	0.4	-0.7	0.4
Lung cancer (father)	0.2	0.3	0.3	-0.5	0.5
Breastfed as a baby	0.2	0.2	0.2	-0.5	0.5
High blood pressure (siblings)	0.2	0.3	0.5	0.2	-0.7
Forced vital capacity (FVC), Best measure	0.2	0.9	1.3	-1.2	0.7
Medication: Seretide 50 evohaler	0.2	0.2	0.3	-0.3	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.3	0.5	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	0.7	0.8	-0.3
Breast cancer (self-reported)	0.2	0.2	0.3	-0.5	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.8	-0.9	0.3
Wears glasses or contact lenses	0.2	0.3	0.3	0.5	-0.5
Commuting to job workplace: Public transport	0.2	0.3	0.4	0.6	-0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.3	-0.4	0.5
Major Depression (MDD)	0.1	0.1	0.3	-0.2	0.5
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.2	-0.1	-0.5
Age at First Birth	0.1	0.1	0.2	0.4	-0.1
Mean Putamen Volume	0.1	0.1	0.1	0.3	-0.3
Blood Eosinophil Count	0.1	0.9	1.0	1.0	-0.9
Allergy or Eczema	0.1	0.2	0.3	-0.5	0.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	0.1	-0.4
Supplements: Zinc	0.1	0.1	0.1	0.3	0.2
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.1	0.4
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	-0.3	0.4
Body mass index (BMI)	0.1	0.3	0.5	0.7	-0.4
Past tobacco smoking	0.1	0.2	0.3	0.5	-0.2
Nervous feelings	0.1	0.2	0.4	0.6	-0.2
Mouth/teeth dental problems	0.1	0.1	0.3	0.2	-0.5
Allergy	0.1	0.1	0.2	0.3	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	-0.1	0.4
Illnesses of siblings	0.1	0.2	0.3	0.5	-0.2
Weight	0.1	0.5	0.6	-0.6	0.8
Alcohol intake versus 10 years previously	0.1	0.1	0.2	-0.2	0.5
Hair/balding pattern: Pattern 3	0.1	0.2	0.2	-0.4	0.4
Asthma	0.1	0.2	0.4	0.2	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.1	-0.4	0.2
Loud music exposure frequency	0.1	0.1	0.2	-0.5	0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.2	-0.4	0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.2	0.5	-0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	-0.1	0.5
Exposure to tobacco smoke outside home	0.1	0.1	0.1	0.3	-0.4
Wheeze or whistling in the chest in last year	0.1	0.2	0.5	-0.1	0.7
Shortness of breath walking on level ground	0.1	0.1	0.2	0.5	-0.1
Neck or shoulder pain in last month	0.1	0.1	0.1	-0.3	0.3
Medication: Ibuprofen	0.1	0.1	0.1	-0.4	0.4
Medication: Allopurinol	0.1	0.2	0.3	-0.5	0.2
Alcohol intake frequency.	0.1	0.2	0.3	0.6	-0.3
Average weekly red wine intake	0.1	0.2	0.3	-0.5	0.3
Asthma (self-reported)	0.1	0.2	0.5	0.1	0.7
Osteoarthritis (self-reported)	0.1	0.1	0.1	0.1	-0.4
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	-0.3	0.4
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.1	-0.4	0.4
Medication: Lisinopril	0.1	0.1	0.2	-0.4	0.3
Medication: Atorvastatin	0.1	0.1	0.1	-0.4	0.2
Average weekly beer plus cider intake	0.1	0.1	0.2	0.4	-0.2
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.0	-0.0	-0.2
Reaction Time	0.0	0.0	0.0	-0.2	0.1
Breast Cancer	0.0	0.1	0.1	0.3	-0.1
Ulcerative Colitis	0.0	0.0	0.0	-0.2	0.0
BMI	0.0	0.2	0.3	0.6	-0.3
Type 2 Diabetes (T2D) (2018)	0.0	0.0	0.0	0.1	-0.2
Lung FVC	0.0	0.2	0.3	0.4	-0.5
Chronotype (morning person)	0.0	0.1	0.1	0.2	-0.3
Hair Pigment	0.0	0.6	0.6	0.8	-0.8
Average weekly spirits intake	0.0	0.0	0.0	-0.1	0.2
Angina	0.0	0.0	0.0	-0.2	0.2
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.1	-0.1
Medication: Co-codamol	0.0	0.0	0.0	0.0	0.1
Current tobacco smoking	0.0	0.0	0.1	-0.3	0.1
Average weekly fortified wine intake	0.0	0.0	0.0	-0.1	-0.0
Relative age voice broke	0.0	0.0	0.0	-0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.0	0.0	0.0	0.0	-0.2
Number of incorrect matches in round	0.0	0.0	0.0	0.1	-0.0
Alcohol usually taken with meals	0.0	0.0	0.1	0.2	-0.3
Had menopause	0.0	0.0	0.0	0.2	-0.1
Had other major operations	0.0	0.0	0.0	-0.1	0.2
Fluid intelligence score	0.0	0.0	0.0	-0.2	-0.2
Time employed in main current job	0.0	0.0	0.0	0.1	-0.1
Father’s age at death	0.0	0.0	0.0	0.2	0.1
Number of live births	0.0	0.0	0.0	0.2	-0.1
Glaucoma (self-reported)	0.0	0.0	0.0	0.1	0.2
Number of children fathered	0.0	0.0	0.0	0.2	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.0	-0.1	0.1
Angina (self-reported)	0.0	0.0	0.0	-0.2	0.0
Mean time to correctly identify matches	0.0	0.0	0.0	-0.1	-0.1
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.1	0.3	-0.0
Medication: Aspirin	0.0	0.1	0.1	0.2	-0.3
Smoking status: Previous	0.0	0.0	0.0	-0.1	0.1
Ever had bowel cancer screening	0.0	0.1	0.1	-0.2	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.1	-0.1
Mineral and other dietary supplements	0.0	0.0	0.0	-0.2	-0.1
Medication: Aspirin	0.0	0.0	0.0	0.1	-0.1
Smoking status: Current	0.0	0.0	0.0	-0.2	-0.0
Illnesses of father: High blood pressure	0.0	0.0	0.1	-0.0	-0.2
Fractured/broken bones in last 5 years	0.0	0.0	0.0	-0.0	0.1
Unable to work because of sickness or disability	0.0	0.0	0.0	-0.0	-0.2
Cholesterol lowering medication	0.0	0.0	0.0	0.2	0.1

Hub : Genes

TBC1D12

Models

Trait associations