[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr11:64,407,419-66,333,072

Best TWAS P=3.76e-09 · Best GWAS P=8.36e-10 conditioned to 0.002

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	The Cancer Genome Atlas	Glioblastoma Multiforme	CTSW	0.16	0.18	enet	16	0.19	2.3e-06	5.1	-5.9	3.8e-09	0.52	0.12	0.75	TRUE
5	GTEx	Colon Transverse	DPF2	0.19	0.01	lasso	4	0.05	1.6e-03	3.4	5.5	3.5e-08	-0.08	0.09	0.07	TRUE
2	GTEx	Brain Cerebellar Hemisphere	EFEMP2	0.35	0.15	enet	5	0.09	2.2e-03	5.5	5.8	6.5e-09	-0.49	0.06	0.84	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DKFZp761E198	0.07	0.02	blup	39	0.03	5.9e-04	-4.8	-5.8	7.8e-09	0.73	0.02	0.62	FALSE
4	GTEx	Cells Transformed fibroblasts	EFEMP2	0.06	0.06	lasso	3	0.07	7.8e-06	5.7	5.8	8.2e-09	-0.45	0.07	0.91	FALSE
3	GTEx	Brain Cerebellum	EFEMP2	0.45	0.40	enet	8	0.39	1.6e-12	5.3	5.6	2.2e-08	-0.48	0.08	0.92	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	EFEMP2	0.04	0.02	lasso	5	0.02	1.4e-05	5.8	5.6	2.3e-08	-0.48	0.04	0.95	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	DPF2	0.03	0.02	blup	28	0.02	1.2e-03	-4.9	5.5	4.6e-08	-0.15	0.00	0.89	FALSE
19	The Cancer Genome Atlas	Soft Tissue Sarcoma	SNX32	0.08	0.08	lasso	2	0.10	1.5e-06	5.7	5.4	5.6e-08	-0.42	0.08	0.91	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DPF2	0.07	0.04	blup	28	0.04	2.9e-05	-4.9	5.4	8.5e-08	-0.16	0.00	0.95	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	DPF2	0.05	0.02	blup	29	0.03	3.7e-04	-4.9	5.3	8.7e-08	-0.14	0.00	0.85	FALSE
14	The Cancer Genome Atlas	Lung Adenocarcinoma	FIBP	0.02	0.01	blup	45	0.02	1.3e-03	3.8	5.3	1.1e-07	-0.48	0.07	0.38	FALSE
16	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POLA2	0.12	0.03	enet	9	0.05	2.5e-04	-4.9	5.3	1.2e-07	-0.13	0.01	0.65	FALSE
18	The Cancer Genome Atlas	Soft Tissue Sarcoma	POLA2	0.09	0.06	blup	34	0.08	1.4e-05	-5.1	5.3	1.2e-07	-0.19	0.01	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FIBP	0.08	0.11	enet	20	0.12	8.1e-14	3.6	5.2	1.5e-07	-0.42	0.99	0.00	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CTSW	0.16	0.10	enet	24	0.15	1.9e-06	3.6	-5.2	1.5e-07	0.44	0.57	0.20	FALSE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	DKFZp761E198	0.14	0.00	blup	39	0.05	1.4e-02	-4.8	-5.2	1.9e-07	0.62	0.01	0.18	FALSE
15	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CAPN1	0.03	0.02	blup	39	0.02	2.1e-03	-4.9	-5.2	1.9e-07	0.18	0.00	0.93	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFEMP2	0.01	0.00	blup	45	0.01	3.0e-02	2.5	5.2	2.1e-07	-0.45	0.04	0.18	FALSE
6	METSIM	Adipose	EFEMP2	0.07	0.05	lasso	8	0.04	4.2e-06	4.8	5.2	2.5e-07	-0.48	0.36	0.64	FALSE