TWAS hub - FIBP

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0850	0.0250	7.8e-10	0.111	0.102	0.115	0.108	0.115	1.9e-13	2.4e-12	8.1e-14	4.6e-13	8.6e-14
2	GTEx	Adipose Subcutaneous	0.0870	0.0400	1.5e-03	0.024	NA	0.021	NA	0.041	4.4e-03	NA	7.5e-03	NA	2.4e-04
3	GTEx	Adrenal Gland	0.2040	0.0946	4.1e-03	0.017	NA	0.129	NA	0.028	7.9e-02	NA	2.3e-05	NA	3.4e-02
4	GTEx	Artery Coronary	0.1260	0.0610	5.9e-03	0.013	NA	0.039	NA	0.044	1.1e-01	NA	1.9e-02	NA	1.3e-02
5	GTEx	Brain Frontal Cortex BA9	0.3694	0.1022	2.9e-03	-0.001	NA	0.060	NA	0.057	3.5e-01	NA	1.1e-02	NA	1.3e-02
6	GTEx	Breast Mammary Tissue	0.0720	0.0360	6.1e-03	-0.001	NA	0.008	NA	0.010	3.7e-01	NA	1.2e-01	NA	9.7e-02
7	GTEx	Breast Mammary Tissue (Female)	0.0756	0.0471	3.8e-02	-0.010	NA	-0.004	NA	-0.010	9.0e-01	NA	4.4e-01	NA	8.6e-01
8	GTEx	Cells EBV-transformed lymphocytes	0.3960	0.0940	1.8e-07	0.214	NA	0.291	NA	0.269	1.5e-07	NA	4.3e-10	NA	2.3e-09
9	GTEx	Cells Transformed fibroblasts	0.2020	0.0480	4.5e-10	0.128	NA	0.166	NA	0.166	7.9e-10	NA	1.9e-12	NA	1.7e-12
10	GTEx	Esophagus Muscularis	0.1080	0.0410	3.6e-04	0.042	NA	0.038	NA	0.043	1.5e-03	NA	2.2e-03	NA	1.2e-03
11	GTEx	Heart Left Ventricle	0.1182	0.0478	3.3e-04	0.086	NA	0.058	NA	0.073	2.5e-05	NA	4.8e-04	NA	9.9e-05
12	GTEx	Muscle Skeletal	0.1155	0.0327	1.8e-08	0.132	NA	0.126	NA	0.124	6.2e-13	NA	2.6e-12	NA	3.4e-12
13	GTEx	Testis	0.2140	0.0630	5.7e-06	0.219	NA	0.156	NA	0.192	4.3e-10	NA	2.0e-07	NA	6.5e-09
14	METSIM	Adipose	0.0497	0.0203	1.3e-04	0.022	0.017	0.014	0.015	0.016	2.7e-04	1.1e-03	3.0e-03	1.8e-03	1.5e-03
15	ROSMAP	Brain Pre-frontal Cortex	0.1286	0.0320	1.4e-12	0.130	0.102	0.145	0.129	0.151	2.3e-16	4.9e-13	3.3e-18	3.2e-16	5.8e-19
16	YFS	Blood	0.0422	0.0130	1.1e-06	0.017	0.025	0.021	0.026	0.020	1.5e-06	1.1e-08	1.3e-07	6.4e-09	3.3e-07
17	TCGA	Breast Invasive Carcinoma	0.0252	0.0131	1.3e-06	0.031	0.032	0.026	NA	0.029	5.0e-07	2.6e-07	3.3e-06	NA	1.1e-06
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0415	0.0239	1.3e-04	0.022	0.038	0.023	NA	0.028	1.4e-03	4.0e-05	1.1e-03	NA	3.9e-04
19	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0520	0.0330	3.8e-03	0.013	0.024	0.015	NA	0.003	5.7e-02	1.5e-02	4.7e-02	NA	2.1e-01
20	TCGA	Brain Lower Grade Glioma	0.0369	0.0202	2.1e-05	0.040	0.038	0.035	NA	0.043	2.4e-05	3.2e-05	6.1e-05	NA	1.1e-05
21	TCGA	Lung Adenocarcinoma	0.0202	0.0138	3.5e-03	0.012	0.021	0.015	NA	0.014	1.2e-02	1.3e-03	5.5e-03	NA	8.6e-03
22	TCGA	Lung Squamous Cell Carcinoma	0.0438	0.0320	7.7e-03	0.010	0.013	0.010	NA	0.011	2.3e-02	1.1e-02	2.2e-02	NA	1.9e-02
23	TCGA	Soft Tissue Sarcoma	0.0590	0.0330	1.7e-03	0.052	0.044	0.043	NA	0.044	4.9e-04	1.2e-03	1.5e-03	NA	1.3e-03
24	TCGA	Thyroid Carcinoma	0.0410	0.0280	9.7e-03	0.000	0.017	-0.002	NA	-0.001	3.2e-01	8.0e-03	6.0e-01	NA	3.7e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Blood Eosinophil Count	11.8	90.7	198.8	-9.9	-7.1	-8.8	-12.3	-3.2	-9.6	-8.8	-11.4	-9.6	-11.3	-10.2	-9.4	-9.0	-8.2	-8.7	-3.4	-14.1	-10.4	-10.2	-10.2	-12.2	-9.7	-7.3	-5.5
Impedance of arm (right)	11.5	53.7	88.5	-7.8	-6.7	-6.6	-9.4	-3.0	-2.6	-5.1	-8.1	-7.4	-7.9	-8.9	-7.6	-7.8	-6.4	-7.0	-6.4	-8.3	-7.4	-8.9	-7.1	-8.8	-7.7	-7.6	-6.9
Impedance of arm (left)	10.6	49.0	82.7	-7.3	-6.6	-6.3	-9.1	-2.8	-2.7	-5.0	-7.8	-7.0	-7.6	-8.6	-7.2	-7.4	-5.7	-6.6	-5.5	-8.1	-7.3	-8.7	-6.8	-8.3	-7.6	-7.4	-6.6
Body mass index (BMI)	9.8	41.6	65.8	8.0	5.2	5.0	7.7	3.3	0.1	3.4	7.3	6.8	6.4	8.1	7.1	7.1	6.2	6.8	5.5	6.8	5.7	7.5	7.3	7.7	7.4	6.8	5.8
Breast Cancer	9.3	22.4	40.2	-5.2	-2.0	-6.3	-5.2	-3.3	-2.3	-5.0	-5.7	-4.7	-5.6	-4.5	-4.8	-4.1	-5.4	-5.0	-3.8	-5.8	-4.5	-5.4	-5.0	-5.8	-3.5	-3.6	-4.2
Age when periods started (menarche)	8.7	20.9	33.1	-4.7	-5.0	-3.5	-4.1	-3.0	-1.1	-3.3	-5.1	-5.3	-4.5	-5.0	-5.1	-5.3	-4.1	-5.2	-5.2	-2.9	-4.8	-5.2	-5.2	-4.3	-4.7	-5.8	-4.7
Impedance of whole body	8.3	42.3	81.8	-6.7	-5.9	-6.7	-9.0	-3.5	-0.9	-3.3	-7.0	-6.3	-6.6	-8.4	-6.5	-6.9	-5.0	-5.9	-4.8	-7.9	-6.3	-8.2	-5.9	-8.0	-7.6	-6.9	-5.8
BMI	8.1	46.8	74.8	8.4	5.1	5.3	8.5	4.2	-0.0	3.7	7.7	7.2	6.3	8.7	7.6	7.7	6.3	7.1	5.5	7.2	5.7	8.0	7.5	8.3	8.3	7.2	5.9
Comparative body size at age 10	7.4	20.4	39.8	5.0	4.0	3.2	6.3	3.3	3.8	3.8	5.0	4.3	4.0	5.6	4.7	5.0	2.8	4.3	2.2	6.0	4.4	4.6	4.5	5.4	6.3	4.3	1.8
Blood Platelet Count	7.3	84.4	156.2	-8.0	-10.1	-5.3	-7.9	-1.9	-9.0	-12.5	-10.4	-9.9	-11.1	-8.4	-10.1	-9.3	-8.0	-9.8	-8.8	-8.1	-11.3	-9.8	-10.1	-8.8	-7.5	-9.7	-9.1
Glaucoma (self-reported)	7.3	8.6	12.6	-3.5	-1.9	-3.5	-3.5	-2.3	-1.3	-2.6	-3.4	-3.0	-2.6	-3.3	-3.2	-3.1	-2.6	-3.1	-2.2	-2.8	-2.4	-3.3	-2.9	-3.4	-3.4	-3.1	-2.4
Type 2 Diabetes (T2D) (2018)	7.0	13.0	25.5	4.3	4.4	1.5	2.2	1.6	1.3	3.5	3.7	4.0	3.4	3.7	4.1	4.2	3.4	4.4	5.1	1.0	3.4	3.5	4.2	3.2	3.2	4.6	4.4
Neck or shoulder pain in last month	7.0	9.9	19.5	4.0	2.6	0.5	2.7	1.6	0.3	1.7	3.8	3.8	3.1	3.5	3.8	3.7	3.4	3.9	3.5	2.7	3.0	3.1	4.4	3.5	3.1	3.1	2.8
Waist circumference	6.8	24.9	38.9	6.2	3.4	3.1	4.7	1.6	-0.4	3.3	5.8	5.5	5.3	5.6	5.6	5.3	6.1	5.3	6.0	4.1	4.4	5.7	5.8	5.9	4.0	5.1	6.2
Leg fat mass (left)	6.5	25.2	51.0	7.1	3.1	3.3	5.3	1.6	0.4	3.6	6.0	5.4	5.2	5.8	5.6	5.2	5.7	5.3	4.6	4.9	4.1	5.6	6.1	6.2	4.9	4.8	5.1
Overall health rating	6.4	13.8	22.7	4.7	2.9	1.9	3.7	2.3	-0.3	3.2	4.3	4.1	3.1	4.6	4.4	4.2	3.7	4.5	3.9	3.1	2.9	4.0	4.8	3.9	4.4	3.9	3.1
Alzheimer’s Disease (including proxy)	6.2	9.0	15.1	-3.1	-3.4	-2.5	-3.7	-2.0	-0.6	-0.6	-3.2	-3.4	-2.6	-3.7	-3.5	-3.7	-2.2	-3.6	-1.9	-2.9	-3.0	-3.3	-3.5	-3.0	-3.9	-3.5	-1.9
Systolic Blood Pressure	6.2	31.2	70.2	5.2	4.9	4.6	3.5	2.3	-1.1	4.1	5.9	5.9	7.2	5.4	5.6	5.2	8.4	5.8	7.8	3.6	6.2	6.5	5.8	5.8	2.7	6.0	8.0
Leg fat mass (right)	6.1	23.8	48.3	7.0	3.1	3.2	5.2	1.4	0.8	3.9	5.8	5.2	5.1	5.6	5.5	5.1	5.5	5.2	4.4	4.8	4.0	5.4	5.9	6.0	4.8	4.6	5.0
Diastolic blood pressure, automated reading	6.1	18.9	45.7	4.2	3.0	2.8	2.5	3.2	-2.0	1.9	4.5	4.9	5.4	4.2	4.5	4.4	6.8	4.4	5.7	2.3	4.7	5.1	4.8	4.3	2.1	5.0	6.4
Had menopause	6.0	7.5	10.6	-2.4	-2.1	-2.2	-2.8	-2.3	-2.5	-2.7	-3.3	-3.0	-3.2	-2.7	-2.8	-2.7	-2.4	-3.2	-3.0	-2.6	-2.9	-3.1	-3.2	-2.8	-2.2	-2.6	-2.8
Impedance of leg (right)	5.9	28.5	64.5	-5.4	-4.8	-5.9	-8.0	-4.0	0.4	-1.9	-5.5	-4.8	-4.9	-7.3	-5.0	-5.7	-3.3	-4.5	-3.1	-6.9	-4.7	-6.9	-4.7	-6.6	-7.1	-5.6	-4.3
HDL Cholesterol	5.8	9.7	15.6	-3.3	-3.1	-3.0	-2.5	-0.1	-1.3	-3.3	-3.3	-3.4	-3.9	-3.1	-3.5	-3.4	-3.9	-3.3	-3.2	-2.5	-3.4	-3.3	-3.4	-3.4	-1.9	-3.1	-3.5
Systolic blood pressure, automated reading	5.8	16.8	30.6	3.8	3.4	2.5	2.9	2.0	-0.4	3.7	4.5	4.5	5.2	4.1	4.2	4.0	5.5	4.1	5.4	3.0	4.6	4.8	4.8	4.4	2.6	4.4	5.4
Arm fat mass (right)	5.7	23.6	43.2	6.6	3.3	3.4	5.3	2.4	-0.3	2.9	5.6	5.1	4.8	5.9	5.4	5.2	5.2	5.2	4.7	4.7	3.9	5.6	5.7	5.8	5.1	4.9	5.0
Impedance of leg (left)	5.5	26.8	61.4	-5.0	-4.6	-5.9	-7.8	-4.1	0.0	-1.9	-5.2	-4.6	-4.7	-7.1	-4.8	-5.5	-3.2	-4.4	-3.1	-6.6	-4.6	-6.7	-4.4	-6.3	-6.9	-5.5	-4.2
Mouth/teeth dental problems: Dentures	5.5	9.3	15.5	3.0	2.9	2.6	3.0	0.2	0.1	2.0	3.3	3.3	3.3	3.5	3.6	3.3	3.9	3.3	3.6	2.5	3.0	3.4	3.3	3.5	2.5	3.2	3.5
Leg fat percentage (left)	5.5	19.8	41.1	6.4	3.3	2.2	4.4	1.0	0.6	3.3	5.3	5.0	4.5	5.1	5.2	4.8	4.9	5.0	4.0	4.0	3.7	4.7	5.8	5.2	4.7	4.4	4.2
Arm fat mass (left)	5.4	22.2	41.7	6.5	3.1	3.4	5.2	2.4	-0.5	2.7	5.4	4.9	4.6	5.8	5.2	5.0	5.1	4.9	4.6	4.6	3.7	5.4	5.5	5.8	5.0	4.7	4.8
Crohns Disease (2017)	5.2	11.4	27.0	2.9	1.4	2.8	4.2	5.2	-0.4	0.7	3.7	3.7	3.1	4.2	3.6	3.7	3.1	3.5	2.5	3.7	3.1	3.9	3.8	3.9	3.8	3.4	2.5
Bilateral oophorectomy (both ovaries removed)	5.0	5.7	9.8	2.5	2.4	1.7	2.1	1.8	1.3	2.3	2.3	2.4	2.7	2.8	2.5	2.6	2.7	2.4	1.5	1.5	2.7	2.9	2.4	2.4	2.1	3.1	3.1
Leg fat percentage (right)	5.0	18.2	37.1	6.1	3.1	2.2	4.2	0.9	1.1	3.5	5.1	4.7	4.3	4.8	5.0	4.6	4.8	4.9	3.8	3.8	3.6	4.5	5.5	4.9	4.5	4.2	4.0
Average weekly spirits intake	4.9	6.1	10.9	3.0	1.9	1.8	3.2	1.9	0.9	1.4	2.9	2.6	2.7	2.9	2.6	2.7	1.9	2.4	1.8	3.0	2.4	2.9	2.7	3.3	2.6	2.3	2.2
Mouth/teeth dental problems	4.9	7.6	12.2	-2.5	-3.0	-1.2	-2.6	-1.0	-1.3	-2.9	-3.1	-3.0	-2.8	-3.1	-3.3	-3.1	-2.2	-3.4	-3.1	-1.9	-2.9	-3.1	-3.5	-2.5	-2.6	-3.2	-2.9
Medication: Levothyroxine sodium	4.8	8.2	14.9	-2.1	-2.9	-1.9	-3.4	-1.9	-1.1	-0.9	-3.1	-3.0	-3.9	-3.1	-3.0	-2.9	-2.4	-2.6	-1.1	-3.6	-3.9	-3.7	-3.0	-3.3	-2.9	-3.2	-2.6
Whole body fat mass	4.6	19.3	41.0	6.4	2.1	2.9	4.4	1.8	-0.3	3.1	5.3	4.8	4.5	5.0	5.0	4.5	5.4	4.6	4.5	4.1	3.3	4.8	5.5	5.5	4.0	4.0	4.8
Crohns Disease (2012)	4.5	7.2	13.2	2.9	1.8	2.5	3.0	3.6	-0.9	-0.6	3.0	3.2	2.3	3.2	3.0	3.2	2.3	2.8	1.9	2.9	2.5	2.6	3.3	3.2	3.2	2.6	1.4
Hayfever/allergic rhinitis (self-reported)	4.5	5.9	14.3	-2.2	-2.4	-3.1	-3.2	-0.2	-2.0	-1.9	-2.7	-2.4	-2.9	-2.6	-2.6	-2.3	-1.9	-2.4	-0.6	-3.8	-2.8	-2.6	-2.3	-3.0	-2.5	-1.9	-1.3
Eye problems/disorders: Glaucoma	4.5	5.3	9.1	-3.0	-1.4	-2.8	-2.9	-1.9	-1.8	-2.6	-2.6	-2.1	-1.9	-2.5	-2.3	-2.3	-1.9	-2.4	-1.7	-2.4	-1.6	-2.4	-2.2	-2.7	-3.0	-2.2	-1.6
Diabetes (mother)	4.4	5.6	14.3	2.4	2.2	1.2	2.1	1.1	-0.2	1.4	2.8	2.6	2.1	2.6	2.8	2.8	2.0	3.0	3.8	1.4	2.3	2.6	2.5	2.3	2.2	2.9	2.8
Arm fat percentage (left)	4.4	17.7	32.7	5.7	3.2	2.7	4.6	2.3	-0.7	2.0	4.8	4.5	3.8	5.4	4.8	4.8	4.2	4.6	3.6	4.0	3.3	4.7	5.2	4.9	5.1	4.4	3.7
Weight	4.3	21.3	42.4	6.5	1.9	3.4	4.8	1.8	-0.3	3.2	5.5	4.8	5.0	5.2	5.0	4.5	5.9	4.6	5.1	4.4	3.3	5.4	5.3	6.0	3.6	4.0	5.8
Breastfed as a baby	4.3	5.3	9.5	-3.1	-2.8	-1.2	-2.0	0.5	-0.4	-1.1	-2.6	-2.6	-2.4	-2.6	-2.8	-2.6	-2.8	-2.8	-2.5	-1.9	-2.1	-2.6	-2.6	-2.6	-1.1	-2.2	-2.5
Arm fat-free mass (right)	4.3	21.8	42.0	6.2	1.7	3.8	5.0	1.5	0.7	4.0	5.5	4.8	5.5	4.8	4.8	4.2	6.0	4.2	5.5	4.7	3.8	5.7	4.7	6.1	2.7	3.9	6.5
Ever had stillbirth, spontaneous miscarriage or termination	4.2	4.5	9.0	-1.9	-2.7	-0.8	-1.8	-1.9	-0.8	-0.9	-2.4	-2.5	-1.5	-2.3	-2.5	-2.7	-1.6	-3.0	-3.0	-1.3	-1.8	-1.9	-2.7	-1.9	-2.6	-2.5	-1.6
Alzheimer’s Disease (in mother)	4.1	4.8	8.9	-2.5	-2.6	-3.0	-2.6	-0.8	-1.3	-0.8	-2.3	-2.3	-1.7	-2.6	-2.6	-2.6	-1.5	-2.8	-1.5	-2.0	-2.3	-1.9	-2.4	-2.0	-2.9	-2.4	-0.6
Smoking Status	4.1	9.9	15.5	3.4	2.2	2.0	2.9	2.2	-0.2	2.6	3.5	3.6	2.8	3.6	3.7	3.8	3.4	3.7	3.5	1.9	3.1	3.4	3.2	3.1	3.4	3.9	3.5
Hayfever, allergic rhinitis or eczema	4.1	8.9	29.6	-2.2	-1.5	-4.4	-3.9	0.2	-5.4	-3.9	-3.4	-2.4	-3.7	-2.3	-2.5	-1.8	-2.6	-2.0	-0.3	-5.1	-3.0	-2.9	-2.2	-3.9	-1.8	-1.0	-1.6
Cardiovascular Disease	4.0	13.3	26.6	3.3	2.9	3.9	2.3	3.5	-2.1	1.6	3.6	4.0	3.3	4.1	3.8	3.9	4.8	4.3	5.1	1.5	2.9	4.1	3.9	3.6	2.6	4.3	5.2
Medication: Blood pressure	4.0	7.0	14.6	2.3	1.9	3.8	1.8	2.7	-3.0	-0.8	2.5	3.0	2.3	2.8	2.6	2.8	3.7	2.7	3.8	1.3	2.1	2.6	2.4	2.7	1.7	2.7	3.0
Arm fat percentage (right)	3.9	15.3	28.3	5.3	3.0	2.6	4.4	2.2	-0.6	1.9	4.5	4.2	3.5	5.0	4.5	4.4	3.7	4.3	3.1	3.8	3.0	4.4	4.9	4.5	4.9	4.1	3.3
Commuting to job workplace: Walk	3.9	4.2	6.8	-2.1	-2.0	-1.5	-2.2	-1.5	-0.7	-1.5	-2.2	-2.2	-2.0	-2.3	-2.3	-2.3	-1.7	-2.3	-2.6	-1.6	-1.9	-2.3	-2.0	-2.3	-1.9	-2.4	-2.4
Current tobacco smoking	3.8	6.2	9.6	2.6	2.6	1.2	2.7	0.5	0.7	3.1	2.8	2.6	2.6	2.6	2.7	2.6	2.5	2.1	2.7	2.2	2.6	3.0	2.1	2.6	2.7	2.9	2.9
Medication: Ramipril	3.8	4.9	8.9	2.6	2.3	2.4	1.6	1.8	-0.6	0.6	2.3	2.7	2.2	2.3	2.4	2.5	2.6	2.4	3.0	1.3	2.2	2.2	2.0	2.4	1.4	2.4	2.5
Arm predicted mass (right)	3.8	19.3	38.4	5.8	1.4	3.7	4.8	1.5	0.4	3.8	5.2	4.4	5.2	4.6	4.4	3.9	5.6	3.9	5.1	4.5	3.4	5.5	4.3	5.9	2.6	3.6	6.2
Arm fat-free mass (left)	3.7	18.9	36.1	5.9	1.4	3.6	4.7	1.9	0.2	3.4	5.2	4.4	5.0	4.7	4.5	4.0	5.4	4.0	5.0	4.3	3.3	5.3	4.4	5.7	2.8	3.7	6.0
Allergy or Eczema	3.6	9.5	40.1	-2.4	-0.7	-4.9	-4.3	0.0	-6.3	-4.4	-3.3	-1.9	-3.7	-2.1	-2.1	-1.3	-2.7	-1.7	0.7	-5.7	-2.6	-2.8	-1.7	-4.1	-1.6	-0.3	-1.4
Body fat percentage	3.6	14.3	31.9	5.7	2.1	2.1	3.6	1.7	-0.4	2.5	4.5	4.2	3.6	4.4	4.4	4.1	4.5	4.3	3.6	3.2	2.7	3.9	5.0	4.5	4.0	3.6	3.6
Smoking status: Current	3.6	5.8	8.7	2.7	2.6	0.7	2.4	0.5	0.9	3.0	2.7	2.5	2.6	2.4	2.7	2.6	2.2	2.1	2.5	2.0	2.5	2.9	2.1	2.5	2.6	2.9	2.8
Average weekly champagne plus white wine intake	3.6	5.0	10.9	-2.3	-1.8	-3.3	-2.2	-2.5	-0.8	-2.2	-2.3	-2.2	-2.4	-2.4	-2.2	-2.1	-2.5	-2.5	-1.5	-2.2	-2.2	-2.2	-2.4	-2.6	-2.0	-2.0	-1.7
Trunk fat mass	3.5	15.2	34.8	5.9	1.3	2.4	3.7	2.1	-0.6	2.6	4.7	4.3	3.9	4.3	4.4	4.0	5.0	4.2	4.2	3.4	2.6	4.2	5.0	4.9	3.4	3.5	4.5
Arm predicted mass (left)	3.5	17.9	33.9	5.7	1.4	3.5	4.6	1.6	0.3	3.4	5.0	4.3	4.9	4.5	4.3	3.9	5.3	3.8	4.8	4.3	3.3	5.2	4.3	5.6	2.7	3.5	5.8
Vascular/heart problems diagnosed by doctor	3.4	9.2	23.1	-2.5	-1.7	-3.3	-1.5	-2.7	2.1	-1.4	-3.1	-3.4	-3.3	-3.0	-3.1	-3.0	-4.4	-3.0	-4.3	-1.3	-2.6	-3.5	-3.3	-3.1	-1.4	-3.3	-4.8
Irritable Bowel Disease (IBD)	3.2	7.5	25.2	2.4	0.9	2.5	3.5	5.0	-0.7	0.2	2.9	2.8	2.1	3.5	2.7	3.0	2.6	2.7	1.3	3.4	2.2	2.7	3.2	3.1	3.7	2.4	0.9
High blood pressure (siblings)	3.2	4.6	7.7	2.5	1.5	1.4	2.0	0.5	-0.5	1.4	2.7	2.8	2.2	2.1	2.5	2.4	2.7	2.2	2.5	2.2	2.0	2.3	2.6	2.5	1.9	2.0	1.8
Qualifications: NVQ or HND or HNC or equivalent	3.2	3.8	9.2	2.0	2.9	0.8	2.5	-0.0	0.3	0.8	2.0	2.0	1.4	2.5	2.3	2.3	1.6	2.5	1.4	2.1	1.6	1.9	2.5	1.9	3.0	2.0	0.5
High blood pressure	3.1	8.6	18.6	2.4	2.0	3.5	1.7	2.1	-2.5	1.2	2.9	3.2	3.1	3.1	2.9	2.8	4.3	2.9	4.3	1.6	2.5	3.4	3.1	3.1	1.7	3.1	4.3
Qualifications: nursing, teaching	3.1	4.8	8.9	-2.5	-1.6	-1.7	-2.4	-0.4	-0.3	-1.1	-2.4	-2.4	-2.4	-2.5	-2.7	-2.5	-3.0	-2.3	-0.8	-3.0	-2.7	-2.2	-2.3	-2.7	-2.1	-2.0	-1.2
Qualifications: College or University degree	3.0	9.6	17.6	-3.8	-2.1	-1.5	-3.1	-2.9	1.6	-1.6	-3.0	-3.1	-2.2	-4.0	-3.7	-3.6	-4.0	-3.5	-4.2	-2.2	-2.1	-3.2	-3.2	-3.5	-3.6	-3.4	-2.8
Hypertension (Self-reported)	3.0	8.5	21.8	2.4	1.8	3.6	1.5	2.4	-3.0	0.8	2.7	3.0	2.9	3.0	2.7	2.7	4.5	2.7	4.5	1.2	2.3	3.3	2.7	3.1	1.4	3.1	4.7
Basal metabolic rate	3.0	16.3	31.6	5.5	1.1	3.5	4.5	1.7	-0.3	2.9	4.8	4.1	4.6	4.4	4.1	3.7	5.2	3.7	4.7	4.1	2.9	5.0	4.0	5.5	2.5	3.3	5.6
Hypothyroidism (self reported)	2.9	6.6	12.7	-1.8	-2.5	-1.9	-3.3	-1.4	-2.0	-2.4	-2.9	-2.6	-3.4	-2.6	-2.5	-2.4	-1.8	-2.0	0.2	-3.6	-3.4	-3.2	-2.6	-2.9	-3.0	-2.6	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.9	3.8	9.5	1.6	1.5	1.3	1.7	2.1	-0.7	1.4	2.1	2.0	1.9	2.3	2.3	2.2	1.3	2.5	3.1	1.2	1.9	2.2	2.0	1.9	1.6	2.3	2.2
Medication for cholesterol, blood pressure or diabetes	2.9	4.9	13.8	-1.9	-1.6	-3.7	-1.5	-2.4	2.0	0.0	-2.2	-2.4	-2.0	-2.4	-2.2	-2.3	-2.7	-2.5	-2.9	-1.3	-1.8	-2.2	-2.0	-2.3	-1.7	-2.3	-2.4
Diabetes (father)	2.8	3.4	9.1	1.9	3.0	1.2	1.1	-0.4	1.4	3.0	1.7	1.9	1.7	1.7	1.8	1.9	0.8	2.1	3.0	0.4	1.8	1.9	1.8	1.4	1.0	2.2	2.4
Leg fat-free mass (left)	2.8	14.7	27.6	5.2	1.1	3.6	4.5	2.2	-0.8	2.4	4.4	3.8	4.1	4.4	3.8	3.5	4.7	3.4	4.1	4.1	2.6	4.8	3.8	5.3	2.9	3.2	5.1
Leg predicted mass (left)	2.8	14.8	28.0	5.2	1.1	3.6	4.6	2.2	-0.8	2.3	4.4	3.8	4.1	4.4	3.8	3.6	4.7	3.4	4.1	4.2	2.6	4.9	3.7	5.3	3.0	3.2	5.1
Length of working week for main job	2.8	3.0	4.6	1.9	0.4	1.0	1.7	1.6	1.0	1.7	2.1	1.8	2.0	1.8	2.0	1.9	1.7	2.0	1.6	1.7	1.9	2.0	2.0	1.9	1.6	1.9	1.8
Exposure to tobacco smoke outside home	2.8	3.8	13.1	1.9	0.9	-0.1	1.3	1.0	-2.1	-0.1	1.8	2.0	1.8	2.2	2.3	2.2	2.5	2.0	3.6	1.0	1.8	2.2	2.1	1.9	1.2	2.2	2.6
Hip circumference	2.7	11.6	24.5	4.9	-0.2	2.9	3.7	2.8	-1.5	1.3	4.0	3.5	3.4	3.8	3.5	3.2	4.8	3.3	2.9	3.8	1.9	3.8	4.0	4.6	3.0	2.5	3.6
Alcohol intake versus 10 years previously	2.7	4.1	10.7	2.1	1.4	1.1	1.1	1.9	-1.2	2.0	1.8	2.2	1.3	2.0	2.1	2.1	2.8	2.3	3.1	-0.4	1.2	2.2	2.1	1.2	1.9	2.9	3.3
Medication: Lansoprazole	2.7	3.0	4.4	1.6	1.6	1.2	2.0	1.9	1.0	0.4	1.9	1.8	1.9	2.1	2.1	2.0	1.0	1.9	1.9	1.8	2.1	1.9	1.8	2.0	1.7	1.8	1.4
Leg fat-free mass (right)	2.7	14.6	28.3	5.2	1.0	3.7	4.6	2.3	-1.1	2.1	4.4	3.7	4.1	4.4	3.7	3.5	4.6	3.3	4.0	4.2	2.5	4.8	3.7	5.3	2.9	3.1	5.1
Leg predicted mass (right)	2.7	14.2	27.9	5.2	0.9	3.6	4.5	2.2	-1.1	2.1	4.3	3.7	4.0	4.3	3.7	3.5	4.6	3.2	3.9	4.2	2.5	4.8	3.6	5.3	2.8	3.1	5.0
Medication: Metformin	2.6	3.7	6.1	2.2	2.4	0.9	1.4	0.4	2.0	2.4	2.2	2.0	1.8	1.9	2.3	2.2	1.2	2.5	2.3	1.0	1.8	1.6	2.3	1.7	1.9	2.2	1.7
Trunk fat percentage	2.6	10.4	25.5	5.0	1.2	1.7	2.9	2.0	-1.0	1.9	3.9	3.7	2.9	3.7	3.8	3.5	4.1	3.7	3.4	2.5	2.0	3.2	4.4	3.9	3.2	3.0	3.3
Stomach or abdominal pain in last month	2.6	3.3	7.4	2.7	1.6	1.8	1.8	1.7	-1.4	0.0	2.0	2.1	1.1	2.3	1.9	2.2	1.7	1.8	2.1	1.8	1.2	1.4	2.0	2.2	2.4	1.7	0.4
Pain all over the body in last month	2.5	2.7	4.5	1.8	1.2	1.7	1.5	1.3	1.0	1.7	2.1	1.9	1.8	1.5	1.9	1.6	1.6	1.9	1.9	1.4	1.4	1.8	1.9	1.7	0.9	1.5	1.8
Lung cancer (father)	2.5	3.0	5.6	1.5	0.7	1.9	2.1	1.7	1.5	1.7	2.0	1.6	2.1	1.8	1.9	1.6	1.5	1.7	0.5	2.4	1.9	2.0	1.8	2.0	1.4	1.5	1.3
Headache pain in last month	2.5	4.3	9.5	-1.6	-3.1	-1.9	-2.2	-0.8	-1.7	-1.3	-2.3	-2.4	-2.0	-2.2	-2.3	-2.4	-1.6	-2.2	-0.5	-1.8	-2.6	-2.2	-2.4	-1.8	-2.5	-2.6	-1.4
Hypothyroidism/myxoedema (self-reported)	2.5	4.9	11.4	-1.4	-1.9	-1.5	-3.1	-1.3	-1.8	-1.4	-2.4	-2.0	-3.2	-2.3	-2.1	-2.0	-1.5	-1.6	0.3	-3.4	-3.3	-2.9	-2.0	-2.6	-2.4	-2.2	-1.8
Alcohol intake frequency.	2.5	5.9	19.8	2.7	0.2	2.7	2.0	2.4	-0.9	1.3	2.4	2.3	2.4	2.7	2.4	2.2	4.5	2.0	2.3	1.6	1.7	2.9	2.3	2.9	1.5	2.4	3.8
Knee pain experienced in last month	2.5	3.9	6.8	2.5	1.0	1.0	1.9	1.2	-0.2	1.6	2.3	2.0	2.0	2.4	2.2	2.0	2.1	2.0	2.2	2.0	1.6	2.2	2.4	2.6	1.8	1.7	2.2
Whole body water mass	2.5	14.1	30.1	5.0	0.8	3.5	4.2	1.6	-0.2	2.8	4.4	3.7	4.3	4.0	3.7	3.3	4.7	3.2	4.4	3.9	2.7	4.8	3.5	5.2	2.1	3.0	5.5
Medication: Bendroflumethiazide	2.5	3.7	12.7	1.8	1.4	2.7	1.8	-0.8	-1.2	0.5	1.9	1.8	2.4	2.1	1.8	1.5	3.6	1.2	1.7	2.5	2.0	2.1	1.8	2.6	1.1	1.2	1.9
Father’s age at death	2.4	3.2	9.2	-2.2	-3.0	-2.0	-1.0	0.0	-0.1	-1.3	-1.5	-1.9	-1.7	-1.9	-2.0	-2.1	-2.3	-2.1	-2.7	-0.6	-1.9	-1.3	-1.5	-1.7	-1.3	-2.0	-1.7
Age at first live birth	2.4	4.2	9.2	-2.5	-3.0	-1.0	-1.7	-0.4	0.4	-1.2	-2.0	-2.4	-1.5	-2.6	-2.6	-2.8	-1.7	-2.5	-1.5	-1.0	-2.1	-1.9	-2.6	-1.7	-2.6	-2.7	-1.3
Smoking status: Previous	2.4	3.5	6.5	1.3	1.4	2.5	1.8	2.2	-0.9	0.8	1.8	2.1	1.4	2.4	2.0	2.3	2.0	2.4	1.9	1.1	1.9	1.9	1.9	1.8	2.0	2.3	1.6
Whole body fat-free mass	2.4	13.6	29.1	5.0	0.8	3.4	4.2	1.4	-0.3	2.7	4.3	3.6	4.3	4.0	3.6	3.2	4.7	3.2	4.3	3.9	2.6	4.7	3.5	5.1	2.1	2.9	5.4
Diabetes diagnosed by doctor	2.4	4.0	9.5	2.4	2.9	0.7	0.9	0.4	0.9	1.9	2.1	2.3	1.6	2.0	2.4	2.5	1.5	2.6	3.1	0.4	1.8	1.5	2.6	1.6	2.0	2.5	1.8
Age at First Birth	2.3	3.4	6.5	-2.2	-2.5	-2.4	-2.0	-0.7	0.9	0.0	-1.7	-1.9	-1.3	-2.1	-2.0	-2.3	-2.1	-1.8	-1.0	-1.2	-1.6	-1.9	-1.9	-1.6	-2.5	-2.4	-1.3
Bipolar Disorder (2011)	2.3	2.2	4.8	1.1	0.7	0.1	1.4	1.6	-1.5	-0.7	1.7	1.9	1.4	1.7	1.7	1.9	0.8	1.4	1.6	0.6	1.4	1.9	1.8	1.4	1.4	2.0	2.2
Body Mass Index (BMI) (2010)	2.3	3.1	5.0	2.1	1.9	1.1	1.7	0.0	1.3	1.5	1.9	1.8	1.9	2.2	2.0	2.0	1.9	2.2	1.3	1.8	1.9	1.5	2.1	1.9	2.0	1.7	0.9
Noisy workplace	2.3	2.8	5.0	2.2	1.0	2.1	1.9	1.3	-1.1	0.4	1.7	1.5	1.5	1.9	1.6	1.5	1.9	1.5	2.1	1.6	0.8	2.2	1.6	2.2	1.3	1.5	2.2
Leg pain on walking	2.3	2.9	6.0	1.5	2.4	1.4	1.2	-0.1	0.4	1.7	1.8	1.8	1.8	1.7	1.8	1.8	1.6	1.9	2.1	0.8	1.7	2.1	1.9	1.4	1.1	2.1	2.3
Schizophrenia vs Biploar Disorder	2.2	2.9	4.8	2.1	1.3	0.6	1.0	0.4	1.8	1.6	2.0	2.1	2.2	1.3	2.1	1.8	2.1	1.9	1.6	1.0	2.1	1.6	2.1	1.6	0.6	1.8	2.0
Type 2 Diabetes (T2D) (2012)	2.2	2.6	6.1	2.2	2.1	1.8	2.0	0.1	1.2	2.1	2.0	1.6	2.0	2.1	2.1	2.0	2.0	2.5	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FEV1/FVC ratio	2.2	11.2	18.2	3.6	4.3	3.1	3.7	-0.1	3.1	2.3	3.6	3.6	3.9	3.3	3.6	3.4	3.1	2.7	2.0	3.6	3.7	4.2	3.3	3.8	2.8	3.4	3.4
Blood clot in the leg (DVT)	2.2	2.8	5.2	1.4	1.0	1.3	1.8	2.1	0.7	0.1	1.8	1.8	1.4	2.1	2.0	2.1	1.2	2.1	1.6	1.1	1.6	1.7	1.9	1.6	2.3	2.2	1.3
Medication: Allopurinol	2.2	2.9	16.1	-0.8	-2.1	0.2	-2.1	1.6	-4.0	-2.3	-1.4	-1.0	-1.6	-1.2	-1.2	-1.1	1.6	-0.9	1.9	-2.8	-1.8	-1.1	-1.4	-1.5	-1.8	-0.6	0.8
Age at last live birth	2.2	3.3	6.2	-2.5	-2.2	-1.9	-1.9	-1.0	0.8	-0.8	-1.8	-2.0	-1.0	-2.1	-2.1	-2.2	-1.8	-2.5	-1.5	-1.3	-1.2	-1.5	-2.3	-1.7	-2.4	-1.9	-0.7
Pain type(s) experienced in last month: Hip pain	2.2	2.8	6.6	1.9	0.8	0.6	1.1	0.6	0.6	1.9	2.0	2.0	1.8	1.6	1.9	1.8	1.9	1.5	2.0	1.0	1.4	1.9	1.9	2.0	1.2	1.8	2.6
Alzheimer’s Disease (in father)	2.1	2.3	4.8	-1.0	-1.6	0.5	-1.7	-1.9	-0.5	-1.0	-1.5	-1.6	-1.2	-1.8	-1.7	-1.9	-0.3	-1.8	-0.5	-1.0	-1.3	-2.2	-1.8	-1.2	-2.1	-2.2	-1.6
Medication: Co-codamol	2.1	2.4	5.6	1.7	0.8	1.1	2.1	1.8	1.0	1.0	2.0	1.7	1.0	1.9	1.8	1.7	1.5	1.4	0.9	2.4	1.1	1.2	2.0	2.0	2.0	0.8	-0.1
Exposure to tobacco smoke at home	2.1	2.3	4.4	1.9	1.4	0.9	1.5	1.0	0.9	0.7	1.7	1.6	1.7	1.6	1.7	1.7	2.1	1.4	1.4	1.4	1.7	1.6	1.6	1.9	1.2	1.6	1.5
Medication: Ventolin 100micrograms inhaler	2.1	2.8	6.6	-1.8	-0.7	-2.6	-1.3	-1.6	-2.3	-1.5	-1.9	-1.6	-2.4	-1.1	-1.4	-1.1	-1.5	-1.8	-1.1	-1.4	-1.7	-1.9	-1.2	-2.0	0.1	-1.1	-2.5
Supplements: Calcium	2.1	2.3	6.8	-1.9	-0.9	-2.0	-1.5	0.0	-0.6	-1.2	-1.6	-1.4	-2.1	-1.4	-1.5	-1.2	-2.6	-1.3	-0.9	-2.1	-1.8	-1.8	-1.2	-1.9	-0.5	-1.1	-1.4
Blood White Count	2.0	14.7	38.6	-3.6	-2.6	-4.7	-4.4	-0.3	-2.9	-2.2	-4.6	-3.9	-5.7	-3.5	-3.6	-3.2	-5.0	-2.5	-1.5	-6.2	-5.3	-4.3	-3.2	-4.9	-2.5	-2.8	-2.4
High blood pressure (mother)	2.0	2.7	7.2	1.9	1.6	1.7	1.3	0.6	-1.3	-0.2	1.6	1.8	1.4	2.0	1.6	1.9	2.3	1.8	2.7	1.3	1.4	1.5	1.7	1.9	1.5	1.6	1.5
Past tobacco smoking	2.0	3.6	6.3	-1.4	-1.4	-1.8	-1.8	-2.1	0.6	-1.5	-1.9	-2.1	-1.7	-2.3	-1.9	-2.2	-1.8	-2.2	-1.9	-1.0	-1.9	-2.3	-2.0	-1.7	-2.0	-2.5	-2.2
Allergy	2.0	4.6	19.9	1.1	0.9	3.6	2.6	-0.9	4.5	3.3	2.1	1.3	3.0	1.1	1.2	0.5	1.8	0.9	-0.4	3.9	2.0	2.1	1.1	2.7	0.1	0.0	1.3
Worrier / anxious feelings	2.0	3.8	8.9	-1.4	-2.5	-2.3	-1.7	0.8	-1.2	-1.0	-1.7	-1.9	-2.5	-1.7	-1.8	-1.8	-2.8	-1.2	-2.1	-1.5	-2.7	-2.4	-0.9	-2.1	-0.7	-2.1	-3.0
Average weekly red wine intake	2.0	3.0	12.0	-2.3	0.6	-2.1	-2.2	-1.1	1.9	1.4	-1.3	-1.0	-1.2	-2.2	-1.6	-1.3	-3.5	-1.1	-2.1	-1.9	-0.5	-1.9	-0.8	-2.3	-0.9	-1.0	-1.9
Medication: Gliclazide	2.0	2.2	4.1	1.7	1.8	1.5	1.4	0.9	-0.8	0.8	1.5	1.6	1.3	2.0	1.6	1.7	1.5	1.7	1.1	1.3	1.1	1.4	1.8	1.8	2.0	1.7	1.0
Mouth/teeth dental problems: Bleeding gums	1.9	2.4	7.3	1.7	1.8	-0.3	1.4	0.4	2.7	2.6	1.8	1.6	1.3	1.4	1.7	1.6	0.1	1.9	1.4	1.1	1.4	1.2	2.1	1.1	1.7	1.4	0.5
Illnesses of father: Heart disease	1.9	2.6	4.6	-1.6	-1.0	-0.8	-2.1	-1.7	-1.1	-1.1	-1.8	-1.6	-1.8	-1.8	-1.9	-1.6	-1.2	-1.8	-1.1	-2.0	-1.4	-1.9	-2.0	-2.1	-1.8	-1.4	-1.4
Medication: Blood pressure	1.9	3.6	14.8	1.2	1.2	1.2	0.1	1.2	-2.4	1.0	1.3	1.8	2.0	1.5	1.7	1.5	3.5	1.3	3.7	-0.0	1.7	1.9	1.2	1.7	0.0	2.0	3.8
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	5.5	1.1	0.7	0.8	1.6	2.4	0.7	0.0	1.7	1.6	1.2	2.0	1.9	2.0	1.1	1.9	1.6	1.0	1.5	1.6	1.8	1.4	2.2	2.0	1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	25.3	1.6	0.2	2.1	0.3	2.4	-3.4	0.1	1.6	1.9	1.7	1.0	1.4	1.6	2.7	1.4	5.0	-0.2	1.4	1.8	0.8	1.5	-0.5	1.8	3.2
Qualifications: None of the above	1.8	3.8	7.7	1.9	1.1	1.9	1.5	2.5	-0.2	1.7	1.9	1.9	2.0	2.0	2.1	1.9	2.8	2.0	2.6	1.1	2.0	2.1	1.6	2.1	1.3	2.2	2.7
Age started oral contraceptive pill	1.8	2.3	8.1	-0.9	-0.3	-1.1	-1.3	-2.0	2.6	1.0	-1.5	-1.6	-1.0	-1.7	-1.3	-1.6	-2.0	-1.4	-2.8	-1.2	-1.1	-1.4	-1.4	-1.4	-1.1	-1.2	-1.0
Standing height	1.7	17.1	61.3	-2.5	-7.0	-3.1	-5.9	-3.0	-1.1	-0.1	-3.3	-3.6	-2.5	-5.8	-4.0	-5.2	-0.1	-4.1	-0.2	-4.7	-4.8	-4.1	-3.8	-3.1	-7.8	-5.4	0.5
Gout (self-reported)	1.7	2.3	17.1	-0.5	-0.9	-0.2	-1.9	1.2	-4.1	-1.8	-0.6	-0.0	-0.6	-0.5	-0.3	-0.2	2.3	-0.2	2.6	-2.6	-0.8	-0.2	-0.4	-1.0	-1.5	0.5	2.0
Medication: Aspirin	1.7	2.2	5.4	1.3	0.5	1.4	0.7	2.3	-0.5	0.3	1.4	1.7	1.6	1.4	1.5	1.6	2.3	1.4	2.3	0.5	1.4	1.6	1.4	1.4	0.6	1.7	2.2
Coronary Artery Disease (CAD)	1.6	1.9	4.9	1.1	1.3	1.5	0.7	2.1	-1.2	0.2	1.2	1.8	0.9	1.4	1.4	1.4	1.8	1.6	2.2	0.2	1.0	1.1	1.4	0.9	1.4	1.7	1.2
Medication: Simvastatin	1.6	2.4	5.4	0.9	1.7	1.6	1.0	2.3	-0.6	0.9	1.5	1.8	0.8	1.8	1.9	2.0	1.1	2.2	2.2	0.4	1.0	1.3	1.7	1.1	2.0	2.0	1.1
Long-standing illness, disability or infirmity	1.6	2.4	4.4	2.1	1.5	1.6	1.3	-0.3	-0.5	1.4	1.9	1.8	1.3	1.8	1.8	1.6	2.1	1.6	1.6	1.8	1.0	1.3	2.0	1.9	1.5	1.0	0.9
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	5.3	-1.6	-0.8	-1.9	-2.3	-1.5	-0.3	-1.1	-1.9	-1.7	-1.3	-2.0	-1.7	-1.7	-1.3	-1.5	-1.0	-2.3	-1.4	-1.6	-1.4	-2.2	-2.2	-1.4	-0.7
Guilty feelings	1.6	2.4	5.2	-1.2	-1.8	-0.2	-2.1	0.2	-2.3	-1.7	-1.5	-1.3	-1.7	-1.4	-1.5	-1.3	-1.5	-1.4	0.0	-1.7	-1.8	-2.1	-1.4	-1.3	-1.9	-1.7	-1.5
Mean Putamen Volume	1.5	1.7	4.6	1.5	1.4	1.9	1.8	-0.3	0.7	0.7	1.4	1.2	1.0	1.6	1.4	1.4	0.7	1.6	1.0	2.1	1.3	1.0	1.0	1.6	1.3	0.8	-0.0
Lupus	1.5	2.3	6.0	1.4	1.0	0.7	0.5	1.5	1.1	2.0	1.7	2.0	1.6	1.0	1.6	1.6	0.5	1.9	2.4	-0.5	1.2	1.5	1.7	0.7	0.9	2.1	2.4
Primary Biliary Cirrhosis	1.5	2.1	3.7	1.2	1.4	1.1	1.5	1.0	-1.5	0.8	1.5	1.5	1.1	1.9	1.5	1.6	1.9	1.3	1.8	1.5	1.2	1.7	1.4	1.6	1.7	1.6	1.2
Townsend deprivation index at recruitment	1.5	2.0	6.9	1.0	0.7	1.6	0.8	0.6	-0.9	1.1	1.3	1.4	1.5	1.3	1.5	1.3	2.2	1.2	2.6	0.5	1.2	1.9	0.9	1.4	0.3	1.6	2.6
Trunk fat-free mass	1.5	8.7	23.1	3.9	0.1	2.9	3.2	0.7	0.0	2.5	3.5	2.8	3.6	2.9	2.8	2.3	4.0	2.4	3.8	3.0	2.0	3.8	2.5	4.1	0.9	2.0	4.8
Time employed in main current job	1.5	1.8	3.2	-1.6	-1.2	-1.5	-1.4	-1.3	0.1	-1.0	-1.3	-1.4	-1.4	-1.4	-1.4	-1.4	-1.5	-1.4	-1.1	-0.7	-1.3	-1.7	-0.8	-1.4	-0.8	-1.7	-1.8
Trunk predicted mass	1.5	8.7	23.5	3.9	0.1	2.9	3.2	0.7	-0.1	2.5	3.5	2.8	3.6	2.9	2.8	2.3	4.0	2.4	3.9	3.0	1.9	3.8	2.5	4.1	0.9	2.0	4.8
Mother’s age at death	1.5	1.8	4.6	-1.0	-1.3	-2.1	-1.1	-1.0	0.7	-0.6	-0.9	-1.1	-1.0	-1.8	-1.3	-1.4	-2.1	-1.2	-2.1	-0.5	-1.2	-1.4	-0.5	-1.3	-1.2	-1.6	-1.9
Medication: Atorvastatin	1.5	1.8	5.7	-1.2	-1.7	-0.4	-2.2	0.4	-1.7	-1.1	-1.4	-1.2	-0.8	-1.6	-1.4	-1.5	0.3	-1.4	-0.2	-1.9	-1.1	-1.2	-1.4	-1.4	-2.4	-1.2	0.3
Pain experienced in last month	1.5	2.6	8.5	-2.9	-0.7	-0.2	-1.3	-0.5	-0.1	-2.0	-1.9	-1.8	-1.4	-1.6	-1.9	-1.7	-1.4	-1.8	-2.3	-1.1	-1.0	-1.4	-2.1	-1.9	-1.2	-1.3	-1.6
Height	1.4	26.1	95.8	-2.1	-9.6	-3.9	-7.4	-3.5	-2.4	-1.6	-3.7	-4.0	-3.3	-6.8	-4.6	-6.0	0.6	-4.8	0.0	-6.1	-6.3	-4.9	-4.4	-3.5	-9.8	-6.5	1.0
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	4.7	2.2	1.0	0.0	0.4	0.1	-0.4	0.0	1.3	1.6	1.2	1.1	1.6	1.6	1.7	1.5	1.9	0.4	1.3	0.8	1.6	1.2	0.9	1.4	1.1
Hair/balding pattern: Pattern 2	1.4	1.7	7.2	-1.4	-2.7	-0.9	-0.6	-0.4	0.1	-1.0	-1.2	-1.5	-1.0	-1.2	-1.4	-1.5	-0.9	-1.8	-2.0	-0.1	-1.1	-0.9	-1.7	-0.9	-1.5	-1.6	-1.2
Medication: Amlodipine	1.4	2.0	10.0	1.3	0.4	0.9	0.1	1.9	-3.2	-1.6	1.0	1.5	0.8	0.9	1.1	1.2	2.4	1.6	2.6	-0.2	0.6	0.9	1.3	0.9	0.1	1.0	1.6
Osteoarthritis (self-reported)	1.4	1.9	6.4	1.1	1.1	-1.0	0.5	0.3	-1.7	-0.6	1.3	1.5	1.1	1.4	1.5	1.4	1.8	1.5	2.5	0.3	0.9	1.4	1.7	1.2	0.5	1.4	2.2
Medication: Aspirin	1.4	1.8	5.0	1.2	0.3	1.4	0.5	2.1	-1.3	-0.6	1.2	1.5	1.3	1.1	1.3	1.4	2.2	1.1	1.9	0.4	1.1	1.4	1.2	1.3	0.3	1.4	1.9
Illnesses of father: None of the above (group 1)	1.4	1.7	3.1	1.0	0.7	0.6	1.6	1.2	1.1	0.4	1.5	1.3	1.8	1.2	1.5	1.2	1.1	1.4	0.5	1.8	1.6	1.6	1.7	1.6	1.1	1.1	1.3
Medication: Omeprazole (e.g. Zanprol)	1.4	1.8	4.9	1.9	0.6	0.1	1.0	0.9	0.8	0.9	1.7	1.8	1.5	1.4	1.4	1.5	1.2	1.3	0.5	1.0	1.4	1.3	2.2	1.6	1.2	1.3	1.2
Ulcerative Colitis (UC)	1.3	2.4	10.1	1.2	0.5	1.8	2.0	3.2	-1.0	-0.5	1.3	1.3	0.7	2.0	1.2	1.6	1.5	1.2	0.2	2.1	1.0	1.0	1.8	1.6	2.7	1.1	-0.6
Fasting Glucose	1.3	1.6	3.2	1.4	1.7	-0.7	0.5	1.0	0.5	0.4	1.3	1.8	1.3	1.1	1.5	1.4	1.1	1.7	1.8	0.1	1.5	1.0	1.5	0.9	0.6	1.5	1.6
LDL Cholesterol	1.3	2.0	10.4	1.4	1.3	0.5	1.4	0.1	3.2	3.0	1.4	0.9	1.1	1.2	1.3	1.1	0.3	1.4	-0.9	1.4	1.0	1.0	1.3	1.0	1.8	1.1	-0.1
Schizophrenia (2014)	1.3	2.8	7.3	1.5	1.2	-0.4	1.3	1.6	1.1	2.3	1.9	1.9	1.7	1.6	2.0	1.9	0.5	2.2	1.2	0.8	1.5	1.8	2.7	1.4	2.0	2.1	1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	22.3	1.0	0.1	2.0	0.0	1.5	-3.3	-0.8	1.3	1.6	1.5	0.7	1.1	1.3	2.3	1.1	4.7	-0.3	1.4	1.4	0.3	1.0	-1.0	1.4	2.7
Birth weight	1.3	2.8	8.8	2.1	1.0	1.5	2.8	0.3	0.1	2.1	2.0	1.3	1.2	1.9	1.5	1.5	1.3	1.5	0.2	3.0	0.9	1.5	1.5	2.2	2.6	0.9	-0.3
Heel T-Score	1.2	9.4	59.6	1.4	0.4	3.0	-1.3	1.5	-7.7	-1.1	1.8	2.5	2.0	1.1	1.8	2.0	5.2	2.2	7.7	-1.3	2.0	1.6	0.8	1.1	-1.9	2.2	4.2
Waist Hip Ratio (WHR)	1.2	5.3	25.3	1.3	3.2	-0.3	-1.0	-2.8	0.6	3.0	1.6	2.0	2.0	1.0	2.0	1.7	2.4	2.0	5.0	-1.7	2.0	1.7	1.6	0.8	-1.2	2.4	4.9
Number of treatments/medications taken	1.2	2.2	12.7	1.3	0.6	1.0	0.8	1.8	-3.6	-1.0	1.2	1.6	0.5	1.8	1.3	1.6	2.0	1.1	1.7	0.6	0.4	1.3	1.7	1.4	1.6	1.4	1.2
Ever had hysterectomy (womb removed)	1.2	1.4	4.8	1.4	0.2	2.2	1.5	0.4	0.3	0.8	1.1	0.9	1.4	1.1	0.9	0.8	1.7	0.4	-0.6	1.8	1.0	1.5	0.7	1.7	0.7	0.7	1.2
Number of incorrect matches in round	1.2	1.9	9.5	1.5	0.2	2.1	1.7	2.4	-3.1	-2.1	0.7	1.1	0.6	1.4	0.7	1.3	0.7	0.5	-0.6	1.2	0.6	1.3	0.3	1.4	1.5	1.2	0.6
Fluid intelligence score	1.2	2.4	4.7	-1.7	-2.2	-0.5	-1.5	-0.7	0.4	0.1	-1.6	-1.9	-1.2	-1.8	-1.9	-2.0	-0.8	-1.9	-1.8	-0.8	-1.4	-1.7	-2.0	-1.6	-1.9	-2.0	-1.4
Qualifications: A levels/AS levels or equivalent	1.2	2.7	4.8	-2.2	-0.6	-1.5	-1.7	-1.9	0.3	-1.1	-1.6	-1.6	-1.1	-2.1	-2.0	-1.8	-1.6	-2.1	-1.8	-1.0	-1.0	-1.5	-1.7	-1.7	-2.1	-1.8	-1.5
Hair/balding pattern: Pattern 4	1.2	3.0	7.2	-1.9	-1.2	-1.2	-2.1	-2.3	0.2	-0.6	-1.8	-1.7	-1.0	-2.4	-2.1	-2.3	-0.9	-2.3	-1.7	-1.5	-1.3	-1.5	-2.1	-1.7	-2.7	-2.0	-0.6
Migraine (self-reported)	1.2	1.5	3.9	-1.4	-0.9	-0.8	-0.6	-0.9	1.0	0.4	-1.2	-1.5	-1.4	-1.0	-1.3	-1.2	-1.8	-1.4	-1.3	-0.4	-1.1	-1.5	-1.4	-1.0	-0.5	-1.5	-2.0
Medication: Omeprazole	1.2	1.4	3.9	1.7	0.7	0.3	0.8	0.9	1.4	1.6	1.5	1.5	1.2	1.1	1.2	1.3	0.8	1.1	0.1	0.8	1.0	1.0	2.0	1.3	1.3	1.1	0.8
Mineral and other dietary supplements	1.2	1.6	5.3	1.0	1.4	1.9	1.8	-1.1	1.9	1.9	1.0	0.5	1.5	1.2	0.8	0.5	1.4	0.5	-0.0	2.3	1.3	1.2	0.7	1.4	1.2	0.4	0.1
Commuting to job workplace: Public transport	1.2	1.4	3.1	-1.3	-0.7	-0.8	-1.4	-1.6	-0.0	0.4	-1.2	-1.4	-0.7	-1.4	-1.4	-1.4	-1.4	-1.4	-1.8	-0.6	-0.5	-1.3	-1.3	-1.0	-1.3	-1.3	-1.1
Fractured/broken bones in last 5 years	1.2	1.6	5.2	-0.8	-0.3	-1.9	-1.2	-2.3	-0.5	-0.9	-1.2	-1.2	-1.0	-1.2	-1.4	-1.4	-1.4	-1.4	-1.9	-1.3	-1.3	-1.1	-0.7	-1.0	-1.2	-1.2	-0.6
Intelligence (Savage-Jansen 2018)	1.1	3.3	6.1	-1.9	-2.5	-1.3	-1.8	-0.7	0.4	-1.3	-1.8	-2.0	-1.8	-2.0	-1.9	-1.9	-1.7	-2.1	-1.3	-1.8	-1.7	-2.0	-2.3	-2.1	-2.3	-1.9	-1.6
Schizophrenia (2018)	1.1	2.3	6.9	1.0	1.6	-1.4	0.9	0.8	1.3	1.8	1.9	1.9	1.7	1.1	1.7	1.7	-0.2	2.1	1.1	1.0	1.8	1.4	2.6	1.0	1.8	1.7	1.1
Maternal smoking around birth	1.1	1.6	6.6	1.3	0.1	1.7	1.3	1.7	-2.6	-0.9	0.9	0.8	0.8	1.7	0.8	1.0	1.5	0.7	1.8	0.9	0.5	1.4	0.5	1.5	0.8	1.1	1.5
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	2.7	1.0	0.4	0.9	1.6	-0.3	1.1	0.7	1.4	1.3	1.0	1.0	1.3	1.2	0.4	1.0	0.2	1.6	1.5	0.8	1.2	1.1	1.5	0.9	-0.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	5.1	1.9	-0.1	1.6	0.4	2.2	-1.3	1.4	1.4	1.3	0.9	1.2	1.2	1.2	1.8	1.4	2.3	0.0	0.4	1.1	1.5	1.2	0.7	1.3	1.7
Depression (self-reported)	1.1	1.3	4.5	-0.8	-1.3	-2.1	-1.4	-0.8	-2.0	-2.0	-0.8	-0.9	-1.1	-0.7	-1.0	-0.8	-0.9	-0.8	-0.0	-0.9	-1.3	-1.3	-0.3	-0.9	-0.9	-1.2	-0.8
Ever highly irritable/argumentative for 2 days	1.1	1.4	2.9	1.3	1.4	1.3	1.2	1.0	-0.5	-0.6	1.2	1.1	0.8	1.7	1.3	1.4	1.1	1.1	1.0	1.4	0.9	1.2	1.1	1.3	1.6	1.2	0.3
Comparative height size at age 10	1.1	5.9	22.7	-1.3	-4.6	-1.4	-3.6	-1.1	-1.3	0.4	-1.7	-1.9	-1.3	-3.3	-2.3	-3.0	0.1	-2.2	0.4	-3.2	-3.1	-2.1	-1.8	-1.5	-4.8	-3.0	1.4
Qualifications: CSEs or equivalent	1.0	1.4	2.9	1.7	1.2	-0.0	0.8	1.2	-0.0	0.9	1.1	1.4	0.5	1.2	1.5	1.5	1.2	1.6	1.7	0.3	0.6	0.9	1.6	0.9	1.3	1.4	0.5
Serious illness, injury or assault to yourself	1.0	1.2	4.4	1.7	0.9	2.1	0.3	0.1	0.7	1.9	1.0	1.1	0.7	0.8	1.2	1.1	1.2	1.1	1.0	0.0	0.9	0.7	1.1	0.7	0.8	1.2	0.8
Financial difficulties in last 2 years	1.0	1.3	7.1	0.8	1.0	-0.4	0.4	-0.1	0.3	1.6	0.9	1.0	1.2	1.0	1.3	1.1	1.2	0.6	1.9	-0.3	1.0	1.7	0.6	0.7	0.3	1.7	2.7
Illnesses of siblings	1.0	1.4	2.7	-1.6	-0.5	-0.9	-0.9	-0.6	1.6	0.4	-1.4	-1.6	-0.9	-1.1	-1.4	-1.4	-1.6	-1.1	-1.4	-1.0	-0.9	-0.9	-1.4	-1.2	-1.2	-1.1	-0.4
Peak expiratory flow (PEF)	1.0	2.4	9.2	1.7	0.6	1.0	0.7	0.1	0.2	0.1	1.7	1.6	2.7	1.1	1.4	1.3	2.2	1.2	1.8	0.8	2.2	1.7	1.6	1.7	-0.3	1.5	3.0
Medication: Paracetamol	1.0	1.6	7.6	-0.6	-2.5	-0.3	-0.8	1.0	-2.8	-2.7	-0.8	-0.8	-1.4	-0.5	-0.9	-0.8	0.3	-0.9	0.1	-0.7	-1.8	-0.9	-0.9	-0.6	-1.2	-1.3	-0.7
Forced vital capacity (FVC), Best measure	1.0	3.6	13.4	-1.4	-2.9	-2.4	-3.1	-1.6	-0.3	0.5	-1.4	-1.6	-0.7	-2.6	-1.8	-2.0	-0.9	-1.4	0.1	-2.9	-1.5	-1.8	-1.4	-1.9	-3.7	-1.8	0.9
Health satisfaction	1.0	1.3	3.0	1.5	1.7	0.6	1.1	-0.5	0.3	1.6	1.4	1.3	0.8	1.4	1.3	1.3	0.5	1.4	0.9	1.3	0.7	1.1	1.7	1.2	1.3	0.9	0.4
Heart disease (mother)	1.0	1.3	5.2	-1.0	-1.3	-1.4	-1.7	0.5	-0.7	-0.6	-1.1	-0.7	-1.5	-1.2	-0.8	-0.8	-1.2	-0.3	0.4	-2.3	-1.3	-1.3	-0.7	-1.7	-1.1	-0.5	-0.6
Friendships satisfaction	1.0	1.2	6.0	-0.5	0.8	-1.7	-1.4	-0.2	0.5	-0.3	-0.8	-0.4	-1.6	-0.8	-0.4	-0.3	-1.9	0.1	-0.8	-1.3	-1.0	-1.7	0.3	-1.4	0.0	-0.6	-2.4
Medication for cholesterol	1.0	1.6	6.3	-0.8	-0.8	-0.9	-0.0	-1.4	1.5	-0.4	-0.8	-1.0	-1.3	-1.2	-1.0	-1.1	-2.2	-0.7	-2.3	-0.3	-1.3	-1.4	-0.5	-1.3	-0.1	-1.4	-2.5
Breast cancer (self-reported)	1.0	1.2	4.5	1.2	-0.7	2.1	1.4	1.4	0.0	-0.4	1.3	1.2	0.9	0.9	1.0	0.7	1.4	1.5	0.9	1.5	0.4	0.8	1.4	1.3	0.5	0.2	0.2
Asthma (self-reported)	1.0	1.9	6.7	-0.4	0.5	-2.3	-1.0	0.3	-2.5	-1.9	-1.4	-0.8	-2.6	-0.2	-0.6	0.1	-1.4	-0.4	-0.3	-1.9	-1.5	-1.7	-0.4	-1.6	1.3	0.0	-2.4
Supplements: Fish oil (including cod liver oil)	1.0	1.3	7.4	-0.5	-1.4	-1.4	-1.4	1.4	-2.2	-2.7	-0.8	-0.3	-1.3	-0.7	-0.6	-0.2	-1.0	-0.3	-0.6	-1.5	-1.0	-1.1	-0.2	-0.8	-0.5	-0.4	-0.7
Ever smoked	1.0	1.8	4.4	0.8	0.8	0.5	1.2	1.4	-0.5	1.1	1.4	1.5	1.1	1.5	1.4	1.6	1.3	1.5	1.8	0.2	1.4	1.9	1.2	0.9	1.4	2.0	2.1
Worry (Nagel 2018)	0.9	1.8	5.4	-1.3	-1.5	-2.2	-1.2	0.8	-0.8	-0.6	-1.2	-1.2	-1.7	-0.9	-1.2	-1.0	-2.3	-0.6	-1.3	-1.1	-1.8	-1.6	-0.3	-1.5	-0.4	-1.3	-2.1
Reaction Time	0.9	1.8	7.6	0.0	2.1	-0.3	0.9	0.6	2.8	2.6	1.0	1.1	0.9	0.8	1.2	1.1	-0.8	1.5	2.0	0.7	1.4	1.0	1.3	0.4	1.3	1.3	0.3
Hair/balding pattern: Pattern 3	0.9	1.3	3.1	-0.6	0.2	-1.1	-1.5	-1.5	1.1	1.0	-0.9	-0.9	-0.7	-1.5	-1.0	-1.1	-1.8	-0.7	-1.8	-1.1	-0.5	-1.4	-0.1	-1.5	-0.6	-0.9	-1.6
Medication: Cholesterol lowering	0.9	1.4	6.6	0.5	1.0	2.6	0.3	2.1	-1.3	-0.0	0.9	1.1	0.7	1.1	1.0	1.2	1.3	1.3	1.9	-0.2	0.8	0.9	0.8	0.7	0.7	1.4	1.5
Chronic bronchitis/emphysema (mother)	0.9	1.1	6.9	0.6	-0.8	1.1	1.3	2.6	-0.5	0.1	1.0	0.9	0.9	1.2	0.9	1.0	0.4	0.8	0.7	1.1	0.8	1.3	0.9	1.0	0.9	1.1	1.1
Financial situation satisfaction	0.9	1.1	3.6	1.1	1.1	0.9	0.6	-0.1	0.3	0.9	0.9	0.9	1.0	1.1	1.1	1.0	1.1	1.0	1.9	0.2	0.9	1.3	0.6	0.9	0.3	1.3	1.9
Average weekly beer plus cider intake	0.9	1.4	5.7	0.9	1.7	0.2	0.5	-0.2	0.9	2.3	0.9	1.0	0.9	0.6	1.2	0.8	0.8	1.1	2.4	-0.3	0.6	1.4	1.0	0.5	0.4	1.4	2.1
Myopia	0.9	1.3	3.2	-1.4	-1.1	0.7	-1.0	-0.0	1.3	-0.1	-1.3	-1.2	-0.9	-1.2	-1.5	-1.3	-1.5	-1.4	-1.8	-0.9	-0.7	-1.0	-1.2	-1.4	-0.9	-1.0	-1.0
Bipolar Disorder (2018)	0.8	1.2	3.5	-1.8	-0.2	-1.5	-0.4	-1.2	-1.0	-0.7	-1.0	-1.1	-1.5	-0.6	-0.9	-0.8	-1.9	-1.0	-1.7	-0.5	-1.4	-0.8	-0.7	-1.2	0.3	-0.9	-1.4
Blood Red Count	0.8	7.8	15.9	2.7	2.2	2.1	2.6	0.6	1.5	3.9	3.2	2.9	4.0	2.7	2.6	2.3	3.2	2.8	0.7	3.8	3.8	2.9	3.8	3.0	2.2	2.2	1.7
Chronotype (morning person)	0.8	1.9	5.2	-0.8	-0.7	-0.6	-1.5	-1.0	-0.6	-1.0	-1.9	-1.9	-1.5	-1.6	-1.7	-1.5	-0.9	-1.4	-0.2	-1.9	-1.4	-1.3	-2.3	-1.7	-1.6	-1.0	-0.6
Average weekly fortified wine intake	0.8	0.9	5.6	-0.7	-1.1	-0.3	0.5	1.2	-0.6	-0.9	-0.6	-0.7	-0.7	-0.4	-0.7	-0.6	-1.5	-0.7	-2.4	0.7	-0.4	-0.5	-0.3	-0.6	0.7	-0.7	-2.0
Multivitamins +/- minerals	0.8	1.0	3.6	-0.5	-1.6	-1.4	-1.7	0.1	-0.5	0.1	-1.0	-0.6	-1.0	-1.4	-1.0	-0.8	-0.9	-0.7	-0.3	-1.9	-0.8	-1.1	-0.9	-1.3	-1.3	-0.6	-0.1
Diabetes (self-reported)	0.8	1.2	3.7	1.5	1.9	0.2	0.0	-0.1	1.0	1.3	1.0	1.2	0.6	0.9	1.3	1.3	0.7	1.4	1.8	-0.3	0.7	0.3	1.5	0.6	1.0	1.2	0.7
Number of live births	0.8	1.1	2.5	-1.2	-1.3	-0.1	-0.9	-0.5	-1.1	-1.1	-1.3	-1.4	-0.9	-0.8	-1.1	-1.0	-1.2	-1.6	-1.0	-1.1	-0.9	-0.5	-1.5	-1.0	-1.0	-0.5	0.0
Prospective memory result	0.8	0.9	2.9	1.7	0.7	-0.2	0.7	0.5	-0.8	-0.7	1.0	1.1	0.7	0.9	1.3	1.1	1.2	1.3	-0.2	0.7	0.6	0.7	1.6	1.1	1.2	0.9	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	4.3	-0.2	0.1	-1.0	-0.3	-0.3	0.2	-0.8	-0.7	-0.7	-1.2	-0.5	-0.7	-0.4	-2.0	-0.6	-2.1	-0.5	-1.0	-1.1	-0.2	-0.9	0.7	-0.6	-1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	2.8	-0.3	-0.7	-0.7	-0.8	-0.7	-1.4	-1.7	-0.7	-0.7	-1.1	-0.8	-0.7	-0.7	-1.3	-0.5	-0.9	-0.8	-0.9	-1.3	-0.4	-1.0	-0.5	-1.0	-1.5
Hearing difficulty/problems: Yes	0.7	1.1	2.4	-1.1	-0.2	-0.4	-0.9	-1.6	-1.4	-1.4	-0.8	-0.9	-1.1	-0.8	-1.1	-1.0	-0.9	-1.5	-1.5	-0.2	-1.2	-0.9	-0.6	-0.6	-0.6	-1.3	-1.3
Relative age of first facial hair	0.7	1.5	9.7	-0.5	-0.5	1.0	1.9	0.6	2.0	0.1	-0.1	-0.6	-0.3	0.7	-0.3	-0.1	-1.7	-0.9	-3.1	2.2	-0.4	0.2	-0.2	0.7	1.4	-0.7	-1.7
Fed-up feelings	0.7	1.2	5.9	1.6	-1.1	0.4	0.5	0.8	1.1	1.8	1.3	0.9	1.1	0.7	1.1	0.7	1.6	0.9	2.4	1.0	0.8	0.4	0.9	1.3	-0.2	0.2	0.8
Medication: Atenolol	0.7	0.8	5.2	-0.4	-0.9	-0.4	-1.3	1.2	-2.0	-0.2	-0.2	0.1	0.3	-0.3	-0.1	-0.2	0.9	-0.2	1.1	-1.4	-0.3	0.5	-0.1	0.1	-1.2	0.3	2.3
Nervous feelings	0.7	1.2	3.3	-1.2	-0.8	-1.8	-1.2	1.3	-1.3	-1.3	-1.2	-1.1	-1.6	-0.6	-0.9	-0.7	-1.3	-0.6	-0.3	-1.5	-1.4	-1.2	-0.6	-1.2	-0.2	-0.7	-0.8
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.4	0.9	1.8	0.4	1.0	-0.2	0.1	0.0	0.9	0.8	0.4	1.4	0.9	1.2	0.3	1.2	1.2	0.8	0.6	0.8	1.1	0.6	1.5	1.1	0.2
Pulse rate	0.7	1.3	4.3	-0.4	0.3	-0.7	-0.5	-0.6	-1.8	-2.1	-1.5	-1.3	-1.3	-0.4	-1.2	-0.7	-1.0	-1.3	-1.7	-0.5	-1.3	-0.9	-1.3	-0.9	0.1	-0.8	-1.5
Asthma	0.7	1.4	5.0	-0.1	0.8	-2.2	-0.8	0.1	-2.1	-1.4	-1.0	-0.6	-2.2	0.0	-0.3	0.3	-1.2	-0.1	0.1	-1.7	-1.2	-1.4	-0.1	-1.3	1.4	0.3	-1.9
Eye problems/disorders: None of the above	0.7	0.9	3.3	0.8	1.6	0.5	1.2	0.4	0.8	1.8	0.9	0.5	0.5	1.0	0.6	0.7	-0.2	0.9	0.3	0.8	0.4	1.2	0.9	0.8	1.7	1.0	0.6
Medication: Seretide 50 evohaler	0.7	0.8	5.7	-0.6	-0.3	-0.8	-0.2	-0.2	-2.4	-2.3	-0.8	-0.7	-1.1	-0.1	-0.4	-0.2	-0.3	-0.5	0.9	-0.4	-0.7	-0.6	-0.8	-0.6	-0.2	-0.5	-0.8
Pulse rate, automated reading	0.7	2.2	8.8	-0.5	-0.6	-0.3	-1.1	-0.4	-1.9	-3.0	-2.0	-1.8	-1.6	-1.1	-1.6	-1.4	-0.3	-1.7	-1.8	-1.0	-1.9	-1.3	-1.8	-1.2	-1.1	-1.5	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	10.2	0.4	-0.1	-0.7	0.6	1.3	3.2	1.5	0.9	0.6	0.5	0.3	0.7	0.5	-0.7	0.9	0.2	0.6	0.4	0.3	0.9	0.5	0.5	0.2	0.0
Illnesses of siblings: Diabetes	0.7	0.9	3.3	0.8	0.6	0.5	0.3	0.6	-1.0	1.1	0.7	0.7	1.2	0.7	0.8	0.8	1.2	0.9	1.5	-0.2	1.1	1.1	0.6	0.5	0.4	1.4	1.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.4	-0.5	-0.7	-0.1	-0.5	-1.6	-0.4	-0.3	-0.7	-0.9	-0.7	-0.9	-1.0	-1.2	-0.3	-1.5	-1.5	-0.3	-1.3	-0.5	-0.7	-0.4	-1.2	-1.3	-0.4
Medication: Lisinopril	0.7	0.9	5.3	0.8	0.3	1.7	0.3	-0.5	-2.3	-1.1	0.5	0.7	0.5	0.9	0.6	0.6	1.4	0.6	1.6	0.5	0.3	0.5	0.4	1.1	-0.2	0.4	0.9
Heart disease (siblings)	0.7	0.8	3.4	-0.7	-1.1	-0.7	-0.7	0.7	-1.3	-1.0	-0.6	-0.4	-1.6	-0.7	-0.5	-0.4	-1.0	-0.3	-0.3	-0.8	-1.4	-1.2	-0.3	-0.9	-0.1	-0.9	-1.8
Triglycerides	0.6	1.0	4.8	1.3	0.7	0.8	-0.3	0.1	0.4	2.1	0.6	0.6	1.2	0.6	0.7	0.7	2.2	0.8	1.6	0.1	1.0	0.8	0.6	0.7	0.2	0.9	1.5
Alcohol usually taken with meals	0.6	1.0	3.8	-1.4	-1.0	-1.9	-1.1	-0.8	-0.1	-0.9	-0.8	-0.6	-0.4	-1.2	-0.9	-0.7	-1.6	-1.1	-1.1	-1.0	0.0	-0.9	-0.9	-1.2	-0.6	-0.5	-0.7
Forced vital capacity (FVC)	0.6	2.4	11.6	-0.5	-2.9	-2.2	-2.6	-0.8	-0.7	0.1	-0.7	-0.8	-0.2	-2.1	-1.1	-1.4	0.3	-0.7	0.6	-2.5	-1.1	-1.1	-0.6	-1.2	-3.4	-1.3	1.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	3.5	-1.0	0.1	-0.7	-0.4	-1.9	-0.7	-1.4	-0.5	-0.9	-0.5	-0.5	-0.7	-0.8	-0.6	-0.8	-0.2	0.1	-0.6	-0.8	-1.1	-0.6	-0.3	-0.9	-0.9
Loud music exposure frequency	0.6	0.6	3.6	0.6	0.0	-0.1	-0.4	1.8	-1.9	-1.1	-0.2	0.1	-0.2	0.2	0.1	0.2	0.9	0.2	1.3	-1.2	-0.5	0.4	-0.1	0.1	-0.1	0.7	1.4
Worry too long after embarrassment	0.6	1.1	3.1	-1.2	-0.8	0.1	-0.6	-0.1	0.4	0.5	-1.2	-1.5	-0.9	-0.9	-1.4	-1.3	-1.5	-1.1	-0.6	-0.2	-0.9	-1.4	-1.3	-0.9	-0.4	-1.3	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.8	-0.2	-1.2	-0.1	-0.7	-0.8	-1.7	-1.4	-0.7	-0.9	-1.1	-0.5	-1.0	-0.8	-0.4	-1.1	-0.6	-0.6	-1.5	-0.8	-0.9	-0.3	-0.8	-1.2	-0.5
Suffer from ‘nerves’	0.6	1.0	5.1	-1.5	-0.4	-1.7	-1.3	0.4	0.3	-0.0	-0.8	-0.8	-1.0	-0.9	-0.8	-0.7	-2.3	-0.6	-0.3	-1.3	-0.8	-1.1	-0.4	-1.4	-0.6	-0.5	-0.9
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.5	0.8	0.8	0.3	1.0	1.2	-0.3	-0.7	0.7	0.9	0.1	1.1	0.9	1.1	0.5	0.8	0.9	0.3	0.3	0.6	1.1	0.6	1.6	1.1	0.2
Supplements: Vitamin C	0.6	0.8	2.5	-0.7	-1.6	-1.5	-0.9	0.1	-0.7	-1.0	-0.6	-0.6	-0.7	-1.1	-1.0	-0.9	-1.0	-0.8	-0.7	-0.6	-1.0	-0.7	-0.4	-0.8	-0.9	-1.0	-0.5
Back pain experienced in last month	0.6	0.9	2.6	1.5	-0.5	0.5	0.2	0.4	-1.4	0.6	0.9	0.9	0.8	0.7	0.8	0.6	1.6	0.4	1.5	0.3	0.2	0.9	1.1	1.1	-0.0	0.5	1.6
Number of self-reported non-cancer illnesses	0.6	1.0	4.9	0.5	0.5	0.4	-0.2	2.0	-2.2	-0.4	0.4	0.8	-0.3	1.0	0.6	1.1	0.7	0.8	2.1	-1.1	0.0	0.5	0.7	0.2	0.7	1.3	1.2
Hearing aid user	0.6	0.6	1.5	-0.9	-1.2	0.3	-0.2	0.2	-1.2	-1.0	-0.7	-0.7	-0.9	-0.6	-0.9	-0.9	-0.4	-1.1	-0.7	0.1	-1.2	-0.6	-0.6	-0.3	-0.5	-1.2	-1.0
Number of operations (self-reported)	0.6	0.9	4.6	0.8	-0.4	2.1	1.0	2.1	-0.1	0.8	0.9	0.9	0.7	1.0	0.8	0.9	0.9	0.6	0.3	0.7	0.8	0.9	0.7	0.8	0.8	1.0	0.7
Prostate Cancer	0.5	0.6	5.4	-0.7	-0.1	-0.0	0.2	0.1	1.6	1.1	-0.2	-0.6	-1.1	-0.5	-0.7	-0.6	-2.3	0.1	-1.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Respiratory disease	0.5	1.0	4.1	-0.1	1.0	-2.0	-0.8	0.7	-1.9	-1.4	-0.4	0.3	-1.2	0.3	0.4	0.9	-0.1	0.7	1.1	-1.5	-0.1	-0.8	0.9	-1.0	1.4	1.0	-1.0
Neuroticism	0.5	1.2	3.9	-0.6	-2.0	-1.5	-1.2	-0.3	-1.2	-0.4	-0.9	-1.2	-1.2	-0.8	-0.9	-1.0	-0.9	-0.7	-0.3	-0.5	-1.3	-1.7	-0.6	-0.9	-0.9	-1.6	-1.8
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.1	1.2	0.3	0.6	0.8	0.1	-1.1	-0.1	0.9	0.7	1.1	1.1	0.8	0.8	0.7	0.7	1.2	1.4	0.8	0.7	0.9	1.5	0.2	0.2	0.6
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.4	1.2	0.8	1.0	0.5	-0.4	-0.4	0.6	1.0	0.9	0.7	1.1	0.9	0.9	1.0	0.9	0.8	0.3	0.6	1.0	1.1	0.8	0.5	0.9	1.2
Relative age voice broke	0.5	0.7	4.4	-0.6	-0.2	0.4	0.9	-0.4	1.6	0.7	-0.1	-0.7	0.0	-0.1	-0.5	-0.6	-1.1	-0.6	-2.1	1.4	0.1	-0.2	-0.4	0.1	0.4	-0.8	-1.4
Wheeze or whistling in the chest in last year	0.5	0.8	3.7	1.2	1.9	-0.1	0.5	-0.3	-1.0	-0.2	0.6	0.7	0.2	1.2	0.9	1.1	0.6	0.8	0.8	-0.1	0.6	0.7	0.8	0.4	1.6	1.5	0.7
Medication for pain relief, constipation, heartburn	0.5	0.9	4.9	-0.9	1.0	0.3	-0.3	-1.7	2.2	1.3	-0.9	-1.1	-0.2	-0.8	-0.8	-0.9	-1.0	-0.7	-1.2	-0.1	0.2	-0.6	-1.2	-0.7	-0.1	-0.4	-0.6
Mean time to correctly identify matches	0.5	1.0	9.2	-0.4	1.3	-0.6	0.2	0.4	3.0	2.7	0.3	0.4	0.2	0.0	0.4	0.3	-1.5	0.6	0.8	0.1	0.5	0.2	0.8	-0.3	0.8	0.5	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.8	0.4	1.3	1.2	0.4	0.0	-0.1	-0.0	0.6	0.8	1.0	0.7	0.8	0.8	0.9	0.6	1.1	0.3	0.9	0.9	0.5	0.6	-0.0	1.0	1.3
Family relationship satisfaction	0.5	0.6	5.4	0.3	2.3	-0.7	0.0	-1.1	1.3	1.1	0.6	0.6	0.1	0.3	0.6	0.6	-0.1	0.6	1.2	0.1	0.2	-0.0	0.7	0.3	0.3	0.3	-0.1
Ever taken oral contraceptive pill	0.5	0.5	3.1	-0.5	-0.2	-0.9	-1.2	0.8	0.8	0.1	-0.7	-0.4	-0.6	-0.5	-0.3	-0.2	-1.0	-0.3	0.7	-1.8	-0.3	-0.5	-0.7	-0.9	-0.8	0.2	0.6
Medication: Paracetamol	0.5	0.8	5.0	-0.1	-1.9	0.4	-0.1	1.1	-2.2	-2.0	-0.2	-0.3	-0.7	-0.0	-0.4	-0.4	0.5	-0.5	0.1	0.3	-1.2	-0.4	-0.5	0.1	-0.5	-1.0	-0.7
Alcohol drinker status: Never	0.5	0.6	2.4	-0.3	-1.2	0.6	0.4	1.6	0.6	-0.4	-0.4	-0.7	-0.7	-0.2	-0.5	-0.5	-0.4	-0.7	-1.5	0.6	-0.8	-0.5	-0.4	0.1	0.3	-0.8	-1.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	3.5	-0.5	-0.6	1.6	0.7	1.9	0.5	0.3	-0.2	-0.3	-0.6	0.2	-0.4	-0.1	-1.2	-0.4	-1.3	0.4	-0.5	-0.2	-0.2	-0.1	0.9	-0.2	-1.1
Commuting to job workplace: Cycle	0.5	0.6	5.2	-0.8	0.3	0.5	0.6	-0.3	1.3	1.0	0.2	-0.2	0.7	-0.3	-0.3	-0.3	-1.5	-0.3	-2.3	1.0	0.7	0.6	-0.2	-0.1	0.0	-0.0	-0.3
Depression (Nagel 2018)	0.4	0.6	2.9	0.7	-0.2	0.2	0.8	0.3	-1.7	-0.1	0.8	0.6	0.8	1.1	0.7	0.7	0.3	0.6	1.2	1.3	0.6	0.6	0.8	1.2	0.4	0.2	0.4
Major Depression (MDD)	0.4	0.5	1.6	-0.9	-0.1	-0.5	-0.6	0.6	-1.2	-0.8	-0.6	-0.7	-0.9	-0.0	-0.6	-0.3	-1.1	-0.3	0.7	-0.4	-0.9	-0.7	-0.2	-0.6	0.1	-0.6	-0.9
Rheumatoid Arthritis	0.4	0.5	2.9	-0.1	-1.0	0.9	-0.5	1.3	-1.7	-0.7	-0.4	-0.3	-0.4	-0.1	-0.3	-0.3	1.1	0.1	0.6	-0.9	-0.7	-0.2	-0.4	-0.0	-0.8	-0.3	0.8
Ulcerative Colitis	0.4	0.6	3.7	0.3	-0.3	0.6	0.6	1.8	-1.9	-1.7	0.0	-0.1	-0.5	0.6	-0.1	0.1	0.4	0.0	-0.7	0.9	-0.5	-0.2	0.2	0.4	1.0	-0.4	-1.1
Vitamin and mineral supplements	0.4	0.5	2.0	0.0	1.1	1.1	1.2	-0.3	1.4	0.3	0.5	-0.0	0.6	0.8	0.6	0.3	0.5	0.3	0.2	1.4	0.4	0.7	0.3	0.7	0.8	0.1	-0.1
Chronic bronchitis/emphysema (father)	0.4	0.5	2.5	-0.3	-0.5	-0.4	0.2	0.5	-0.6	-0.1	-0.6	-0.7	-1.3	-0.0	-0.5	-0.3	-1.6	-0.5	-1.1	-0.1	-1.0	-0.4	-0.7	-0.6	0.7	-0.3	-1.4
Falls in the last year	0.4	0.5	3.6	-0.9	-0.7	-0.3	-0.1	-0.2	-1.9	-1.4	-0.7	-0.8	-0.3	-0.2	-0.7	-0.6	-0.5	-0.9	-0.1	0.1	-0.5	-0.2	-0.9	0.2	-0.4	-0.6	0.1
Happiness	0.4	0.5	2.2	1.2	1.1	0.3	-0.1	-0.9	0.1	0.4	0.6	0.7	0.7	0.5	0.6	0.5	1.1	0.7	1.5	0.2	0.4	0.5	0.6	0.8	-0.5	0.2	1.0
Illnesses of mother	0.4	0.5	2.9	-0.6	0.3	0.1	-0.1	-0.7	1.0	-0.4	-0.7	-0.6	-0.6	-0.7	-0.5	-0.6	-0.7	-0.7	-1.7	-0.3	-0.3	-0.8	-0.9	-0.6	0.0	-0.5	-1.2
Pulse wave Arterial Stiffness index	0.4	0.5	2.8	-0.3	-1.7	0.5	-0.6	0.2	-1.3	0.1	-0.6	-0.6	-0.7	-0.6	-0.6	-0.8	0.1	-0.9	-0.6	-0.6	-0.9	-0.6	-0.7	-0.4	-0.7	-0.7	-0.2
Tense / ‘highly strung’	0.4	0.6	2.9	0.4	-0.8	-1.7	-0.2	1.6	-1.6	-1.0	0.1	0.3	-0.7	0.3	0.2	0.4	-0.7	0.6	0.4	-0.5	-0.8	-0.3	0.9	0.0	0.5	-0.1	-0.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.7	-0.8	-0.6	-0.5	-0.6	-0.7	-0.1	-1.0	-0.7	-0.6	-1.2	-0.7	-0.8	-0.5	-1.0	-1.3	-0.3	-0.6	-1.0	-1.0	-0.9	-0.7	-0.2	-0.7	-1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	4.2	-0.4	0.9	-1.3	-0.5	-0.5	2.1	1.4	0.1	0.0	-0.2	-0.2	-0.0	0.0	-1.2	0.4	0.1	-0.7	0.3	-0.3	0.3	-0.8	0.3	0.3	-0.3
Handedness (chirality/laterality): Left-handed	0.4	0.5	3.0	-1.0	-0.7	-0.9	-0.2	0.2	-0.0	-0.2	-0.6	-0.6	-0.6	-0.6	-0.7	-0.7	-1.7	-0.8	-1.2	-0.4	-0.6	-0.3	-0.6	-0.7	-0.2	-0.5	-0.3
Wears glasses or contact lenses	0.4	0.5	2.3	-0.1	-0.5	0.4	0.6	-0.6	-0.1	-0.6	-0.5	-0.6	-0.7	0.1	-0.6	-0.4	-0.7	-0.9	-1.4	0.8	-0.6	-0.4	-0.2	-0.0	0.9	-0.8	-1.5
Basal cell carcinoma (self-reported)	0.4	0.5	5.0	0.4	0.5	1.0	1.0	0.6	2.2	0.7	0.4	-0.2	0.5	0.5	0.1	0.1	-0.5	-0.1	-0.9	0.9	0.4	0.6	0.0	0.5	0.9	0.4	0.2
Bipolar Disorder or Schizophrenia	0.3	0.8	4.0	-0.3	1.1	-2.0	0.4	0.1	0.4	1.2	0.9	0.8	0.3	0.4	0.8	0.8	-1.3	1.0	-0.2	0.4	0.6	0.6	1.6	0.1	1.6	0.8	-0.1
Neuroticism (Nagel 2018)	0.3	0.7	2.7	-0.3	-1.2	-1.6	-1.1	-0.1	-1.0	0.1	-0.6	-0.5	-0.8	-0.5	-0.4	-0.4	-0.8	-0.3	0.5	-0.6	-0.9	-1.3	-0.0	-0.6	-0.6	-1.0	-1.4
Hand grip strength (left)	0.3	0.8	3.7	0.2	-1.2	-1.4	-0.8	0.8	0.5	0.3	-0.5	-0.8	-0.3	-0.5	-0.8	-0.7	-0.2	-0.4	0.9	-1.5	-1.2	-0.1	-0.6	-0.3	-1.4	-0.4	1.9
Sensitivity / hurt feelings	0.3	0.5	2.9	-0.2	-1.7	-0.0	-0.4	0.2	-1.4	-0.9	-0.6	-0.7	-0.2	-0.5	-0.6	-0.7	0.1	-0.6	-0.1	0.2	-0.3	-0.6	-0.9	-0.1	-1.1	-1.0	-0.6
Angina	0.3	0.4	1.9	-0.2	-0.9	-0.3	-1.4	0.3	-0.3	-0.4	-0.5	-0.3	-0.1	-0.7	-0.4	-0.5	0.3	-0.4	-0.0	-1.0	-0.4	-0.4	-0.2	-0.7	-1.3	-0.5	0.4
Medication for hormone replacement therapy	0.3	0.3	1.3	0.2	0.1	0.2	0.8	1.1	-0.7	-0.9	0.1	0.1	0.6	0.7	0.1	0.3	0.2	-0.2	0.1	1.0	0.9	0.7	-0.2	0.7	0.3	0.4	0.5
Pack years adult smoking proportion	0.3	0.4	2.0	0.6	-0.2	-0.5	-0.2	-1.2	1.1	1.4	0.1	-0.4	0.2	-0.1	-0.0	-0.3	0.3	-0.1	0.7	-0.5	-0.2	0.4	-0.5	-0.0	-0.9	-0.0	1.3
Supplements: Glucosamine	0.3	0.4	1.0	0.3	0.6	-1.0	-0.7	0.2	-0.6	-0.2	0.5	1.0	0.2	-0.0	0.7	0.8	-0.1	0.8	0.9	-1.0	0.4	0.1	0.8	-0.2	-0.0	0.9	0.8
Sitting height	0.3	1.9	10.1	0.7	-2.5	0.3	-1.8	-2.1	0.3	1.8	-0.3	-0.8	0.4	-2.1	-0.8	-1.6	1.5	-0.6	0.2	-0.7	-0.7	-1.1	-0.8	-0.4	-3.2	-1.9	0.3
Heart attack	0.3	0.4	2.1	-0.2	-0.5	1.0	-0.7	0.7	0.6	0.9	0.1	0.2	0.7	-0.4	0.0	-0.2	0.8	-0.0	0.1	-0.2	0.6	0.3	-0.4	-0.1	-1.4	0.0	0.9
Neuroticism score	0.3	0.7	2.2	-0.4	-1.5	-1.1	-1.0	0.1	-0.8	-0.1	-0.7	-1.0	-0.8	-0.5	-0.7	-0.8	-0.7	-0.6	0.3	-0.3	-0.9	-1.3	-0.5	-0.5	-0.7	-1.2	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.0	5.4	-0.5	-1.4	-1.5	-1.7	-1.3	0.4	0.5	-0.5	-0.5	0.3	-1.4	-0.7	-0.9	-0.3	-0.6	-0.1	-1.6	-0.3	-0.6	-0.4	-0.8	-2.3	-0.6	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.0	0.9	-0.4	-0.4	0.9	-1.4	-0.4	1.3	0.8	0.3	0.3	0.7	0.4	0.2	-0.2	0.2	-0.3	1.3	-0.2	0.5	1.0	0.8	0.6	-0.3	-0.3
Pulse wave reflection index	0.3	0.4	2.6	-0.8	-1.6	0.6	-0.1	0.9	0.9	1.6	0.0	-0.1	0.5	-0.4	-0.3	-0.5	0.3	-0.4	-0.1	0.2	0.4	0.1	-0.2	0.1	-0.8	-0.3	0.6
Number of full brothers	0.3	0.4	2.4	-0.0	0.4	-1.5	-0.8	-0.1	0.1	0.5	0.6	0.8	0.3	-0.5	0.5	0.4	-0.3	0.6	1.2	-1.1	0.3	0.1	0.7	-0.4	-0.5	0.6	0.9
Shortness of breath walking on level ground	0.3	0.3	1.3	0.4	0.1	-1.0	-0.1	-1.2	1.0	0.9	-0.0	-0.5	-0.2	-0.1	-0.3	-0.4	-1.0	-0.7	-0.7	0.3	-0.4	-0.1	-0.0	-0.0	0.5	-0.3	-0.4
Emphysema/chronic bronchitis	0.3	0.3	3.6	0.5	0.4	-0.8	0.1	-0.2	1.9	0.8	0.5	0.5	0.5	0.0	0.6	0.4	-0.1	0.4	0.1	-0.0	0.8	0.2	0.5	0.1	0.2	0.4	0.4
Medication: Ibuprofen	0.3	0.4	2.0	-0.2	-1.0	1.2	0.9	0.7	-1.4	-0.9	0.3	0.2	0.1	0.5	0.1	0.2	0.1	-0.2	-0.2	1.0	-0.2	0.6	0.0	0.6	0.1	-0.1	0.0
Chest pain or discomfort	0.3	0.4	3.2	0.5	0.7	0.6	-0.5	-1.1	-0.8	0.3	0.5	0.6	0.4	-0.0	0.2	0.2	1.0	0.5	1.8	-0.2	0.2	0.0	0.5	0.1	-0.5	0.1	0.3
Had major operations	0.3	0.3	3.5	0.5	-1.0	1.9	-0.3	0.7	-1.1	0.6	0.3	0.4	-0.1	-0.1	0.3	0.1	0.4	0.1	-0.4	-0.2	-0.2	0.0	0.2	0.0	-0.1	0.1	0.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.2	-0.0	0.4	0.1	0.6	0.2	1.4	-0.3	0.2	0.4	0.3	0.1	0.1	0.2	0.1	0.3	-1.2	1.2	0.6	-0.4	0.6	0.4	0.6	-0.3	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.9	-0.4	-1.7	-0.8	-1.1	0.1	0.3	0.8	-0.4	-0.6	-0.1	-1.2	-0.4	-0.9	0.2	-0.7	1.1	-0.9	-0.6	-0.6	-0.7	-0.4	-1.6	-0.8	0.7
Mood swings	0.3	0.6	2.4	1.6	-0.2	-0.7	0.2	-0.7	-0.1	1.3	0.9	0.6	0.7	0.6	0.8	0.5	1.1	0.7	1.5	0.8	0.5	0.1	1.1	0.8	0.4	0.1	0.0
Loneliness, isolation	0.3	0.4	1.7	0.3	0.3	-1.3	-0.6	-0.2	0.9	0.8	0.5	0.4	0.6	0.3	0.7	0.6	0.4	0.5	1.3	-0.7	0.5	0.3	0.6	0.2	-0.2	0.7	1.3
Ever had bowel cancer screening	0.3	0.3	1.8	0.5	0.4	1.3	0.8	0.4	1.0	0.5	0.5	0.4	0.0	0.6	0.3	0.3	-0.2	0.3	-0.5	0.6	-0.2	0.3	0.5	0.5	0.6	0.0	-0.2
Miserableness	0.3	0.5	2.6	0.2	-0.3	-1.5	-1.2	-1.6	0.5	0.9	-0.2	-0.4	0.0	-0.6	-0.4	-0.5	-0.4	-0.4	0.7	-0.6	-0.1	-0.8	-0.2	-0.3	-1.1	-0.7	0.1
Illnesses of father: High blood pressure	0.3	0.4	1.3	-0.5	-1.2	-0.8	-0.6	0.8	-0.8	-0.3	-0.7	-0.6	-0.5	-0.4	-0.8	-0.5	-0.3	-1.0	-0.3	-0.9	-0.9	-0.2	-0.5	-0.6	0.1	-0.1	0.2
Risk taking	0.3	0.4	3.1	0.6	0.6	-0.9	-0.1	-1.8	0.8	0.5	0.2	0.1	0.5	-0.1	0.3	0.2	-0.3	0.2	0.1	-0.5	0.6	0.3	-0.3	-0.1	-0.6	0.5	1.2
Ever depressed for a whole week	0.3	0.4	1.7	0.7	0.9	0.5	1.0	-0.7	1.3	0.7	0.5	0.3	0.3	0.7	0.4	0.5	-0.9	0.4	0.2	0.9	0.4	0.3	0.5	0.5	0.9	0.3	-0.3
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.7	0.0	-0.3	1.3	-0.5	0.9	0.3	0.7	0.2	0.3	0.7	-0.2	0.1	-0.0	0.9	0.1	0.1	-0.1	0.7	0.3	-0.4	0.1	-1.2	0.1	0.9
Alcohol drinker status: Previous	0.3	0.4	2.2	-0.9	-1.5	0.2	-0.5	1.0	-0.1	0.5	-0.5	-0.6	-0.4	-0.3	-0.6	-0.6	-0.7	-0.5	-0.9	-0.6	-0.5	-0.2	-0.7	-0.3	-0.5	-0.4	0.5
Pack years of smoking	0.3	0.4	2.4	0.7	0.1	-0.2	0.0	-1.3	1.1	1.3	0.4	-0.1	0.5	0.1	0.2	-0.1	0.6	0.1	1.0	-0.3	0.1	0.6	-0.2	0.3	-0.8	0.2	1.6
Depressed Affect (Nagel 2018)	0.2	0.4	2.1	0.7	-0.7	-1.1	-0.7	-1.4	-0.3	0.7	0.1	0.0	0.1	-0.0	0.2	-0.0	0.6	0.2	1.4	-0.1	-0.2	-0.8	0.4	0.2	-0.9	-0.7	-0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.4	4.1	-0.2	-2.0	0.2	0.2	1.3	0.7	-0.2	0.1	-0.2	0.6	-0.1	-0.1	-0.3	0.5	-0.3	-0.4	0.7	0.3	-0.0	-0.2	0.2	-0.7	-0.5	-0.1
Ovarian Cancer	0.2	0.3	3.5	0.4	-0.0	0.8	0.2	0.5	-1.9	-0.3	0.1	0.2	-0.2	0.4	0.1	0.2	0.5	0.1	1.1	-0.2	-0.3	0.2	-0.2	0.4	0.2	0.3	0.7
Neuroticism (2016)	0.2	0.3	1.1	0.7	0.5	0.3	-0.8	-0.4	-1.1	-0.4	0.2	0.2	0.1	0.1	0.2	0.0	0.8	0.2	0.8	0.0	-0.0	-0.8	0.3	0.3	-0.7	-0.6	-0.8
Lung FVC	0.2	0.9	3.7	0.3	-0.6	-1.1	-0.8	0.3	-1.2	0.5	0.9	1.2	0.8	-0.0	0.7	0.8	-0.1	1.5	1.3	-1.4	0.8	0.5	1.1	-0.2	-0.8	1.1	1.9
Hair Pigment	0.2	7.0	31.1	-1.1	-4.1	-1.1	-0.3	0.8	0.8	-4.3	-1.5	-2.1	-2.7	-2.1	-2.4	-2.2	-3.8	-2.8	-5.6	0.1	-3.5	-2.0	-1.9	-1.1	-0.9	-3.2	-3.8
Tanning	0.2	2.8	6.9	-1.4	-0.6	-0.2	-0.5	-1.7	-0.1	0.3	-2.1	-2.5	-2.5	-1.0	-2.0	-1.7	-2.6	-1.6	-1.4	-0.6	-1.9	-1.8	-2.6	-1.5	-0.3	-1.7	-2.4
Ever used hormone-replacement therapy (HRT)	0.2	0.3	3.2	0.2	-0.2	-0.2	0.1	0.8	-1.8	-1.4	-0.2	-0.0	-0.2	0.4	-0.0	0.2	0.3	-0.6	0.3	0.0	-0.1	0.2	-0.2	0.4	0.6	0.4	0.4
Supplements: Zinc	0.2	0.3	3.1	-0.1	0.3	-0.3	0.2	0.0	1.8	1.3	-0.1	-0.1	0.1	-0.1	0.0	0.0	-1.0	0.0	-0.5	0.1	0.2	0.1	-0.2	0.0	0.1	0.1	0.1
Severe depression (siblings)	0.2	0.2	2.3	-0.4	0.0	0.3	0.4	-0.1	-0.6	-1.5	-0.1	-0.1	-0.4	0.2	-0.2	0.1	-0.5	0.0	0.7	0.1	-0.3	-0.2	-0.6	0.1	-0.0	-0.3	-0.2
Hand grip strength (right)	0.2	0.6	4.2	0.9	-1.4	-0.5	-0.6	0.7	0.3	0.5	-0.2	-0.4	0.3	0.1	-0.2	-0.3	1.2	-0.2	1.2	-0.8	-0.6	0.2	-0.1	0.4	-0.9	-0.1	2.0
Taking other prescription medications	0.2	0.4	3.8	-0.1	-0.6	-0.3	-0.1	0.8	-1.9	-0.9	0.0	0.3	-0.8	0.4	0.1	0.3	-0.1	-0.1	1.1	-0.4	-0.7	-0.3	0.4	0.0	0.2	-0.1	-0.2
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	2.2	-0.7	-0.3	0.3	0.1	1.4	-1.5	-0.9	-0.1	-0.0	-0.2	0.1	-0.3	-0.0	-0.7	0.2	-0.3	0.1	-0.5	0.3	0.0	-0.2	0.1	-0.0	-0.2
Hearing difficulty/problems with background noise	0.2	0.3	1.1	-0.8	0.1	-0.2	-0.9	0.6	-0.8	-0.5	-0.4	-0.3	-0.8	-0.4	-0.4	-0.3	-1.1	-0.1	0.0	-0.9	-0.6	-0.7	-0.0	-0.6	-0.2	-0.3	-0.7
Had other major operations	0.2	0.2	1.2	0.1	-0.7	1.1	-0.6	0.5	-0.5	-0.4	-0.4	-0.4	0.1	-0.1	-0.5	-0.4	0.6	-0.5	-0.0	-0.6	-0.1	-0.1	-0.4	-0.1	-0.8	-0.1	0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	5.6	-0.0	-1.4	-1.3	-1.4	-1.0	0.1	0.1	-0.0	0.0	0.8	-1.1	-0.3	-0.6	0.6	-0.2	0.4	-1.2	0.1	-0.2	0.1	-0.3	-2.4	-0.4	1.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.9	-0.3	-1.0	0.7	0.6	0.5	-1.4	-1.1	0.2	0.1	-0.1	0.4	0.1	0.2	-0.1	-0.1	0.1	0.5	-0.4	0.5	-0.1	0.4	-0.1	-0.1	0.3
Number of children fathered	0.2	0.3	1.2	1.1	-1.0	0.9	0.7	0.7	-0.2	0.6	0.4	0.3	0.1	0.4	0.3	0.3	0.8	0.6	0.4	0.2	0.0	0.3	0.4	0.3	0.3	0.2	-0.0
Pulse wave peak to peak time	0.2	0.2	1.6	-0.1	1.0	-0.9	-0.0	-0.5	1.3	-0.1	0.2	0.1	0.3	-0.0	0.1	0.2	-0.4	0.4	0.4	0.1	0.3	0.1	0.2	-0.0	0.1	0.1	0.1
Angina (self-reported)	0.2	0.2	1.4	-0.0	-0.8	-0.1	-1.2	0.7	-0.1	-0.1	-0.3	-0.1	-0.1	-0.6	-0.3	-0.3	0.4	-0.2	-0.1	-0.9	-0.4	-0.3	-0.0	-0.5	-1.0	-0.3	0.5
Number of full sisters	0.2	0.2	2.5	-0.5	0.2	-0.5	-0.2	-1.0	-1.6	-0.4	-0.4	-0.0	-0.3	-0.2	-0.1	-0.2	0.0	-0.5	-0.0	-0.7	-0.4	0.1	-0.4	-0.3	-0.2	0.0	0.6
Osteoporosis (self-reported)	0.2	0.2	1.4	-0.2	0.8	0.8	0.4	-1.2	0.6	-0.2	-0.1	-0.0	0.0	0.2	0.2	0.2	-0.5	-0.1	0.1	0.1	0.5	0.2	-0.6	0.1	0.2	0.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	1.0	-0.0	0.8	1.0	0.9	0.2	-0.1	0.3	0.7	0.8	0.6	0.6	0.6	0.7	-0.5	0.7	-0.2	0.6	0.7	0.8	0.7	0.5	0.4	0.7	0.5
High cholesterol (Self-reported)	0.2	0.4	3.5	0.3	0.3	0.9	0.3	1.9	0.2	0.6	0.5	0.5	-0.1	0.5	0.5	0.6	0.1	0.9	0.5	-0.1	-0.1	0.3	0.6	0.2	1.0	0.6	0.1
Irritability	0.2	0.3	2.4	0.4	-1.1	-1.6	-0.4	-1.1	-1.0	0.3	-0.0	-0.2	-0.3	-0.3	-0.1	-0.3	0.4	-0.3	-0.0	-0.0	-0.4	-0.4	0.2	-0.1	-0.1	-0.5	-0.4
Unable to work because of sickness or disability	0.2	0.2	0.7	0.0	-0.8	0.1	0.2	0.6	0.6	0.8	0.5	0.2	0.8	-0.2	0.2	-0.2	0.5	0.0	0.5	0.7	0.3	0.5	0.1	0.5	-0.6	-0.3	0.7
HbA1C	0.1	0.1	0.7	0.2	-0.3	-0.1	-0.3	0.3	-0.1	0.4	-0.4	-0.3	-0.6	-0.5	-0.3	-0.1	-0.5	-0.4	-0.3	-0.5	-0.2	-0.5	-0.2	-0.6	0.2	-0.0	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.6	0.7	-0.6	-0.6	-0.1	0.2	-0.6	0.6	0.5	0.4	-0.2	0.1	0.4	0.4	-0.8	0.4	0.5	0.1	-0.3	-0.1	0.7	0.1	0.2	0.0	-0.6
Birth weight of first child	0.1	0.2	1.0	0.4	-0.2	-0.0	0.5	0.8	0.7	1.0	0.2	-0.2	-0.4	0.1	-0.2	-0.1	-0.6	0.1	0.3	0.1	-0.7	0.3	-0.1	-0.0	0.0	-0.1	0.0
Eye problems/disorders: Cataract	0.1	0.2	0.9	-0.1	-0.7	-0.1	-0.5	-0.2	0.1	-0.9	-0.1	0.2	0.0	-0.3	0.1	-0.0	0.8	-0.1	0.1	-0.3	0.2	-0.6	-0.3	-0.1	-0.7	-0.3	-0.2
Cholesterol lowering medication	0.1	0.2	1.3	0.0	-0.7	-0.3	-0.7	0.6	0.3	1.1	-0.2	-0.3	-0.4	-0.3	-0.1	-0.3	0.2	-0.0	-0.3	-0.4	-0.5	-0.3	-0.0	-0.3	-0.1	-0.4	-0.2

Hub : Genes

FIBP

Models

Trait associations