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chr13:49,409,343-52,109,040

Best TWAS P=1.89e-25 · Best GWAS P=1.36e-58 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	NTR	Blood	DLEU7	0.07	0.02	enet	22	0.06	1.3e-19	-6.53	-10.4	1.9e-25	0.61	0.11	0.89	TRUE
11	GTEx	Nerve Tibial	DLEU2	0.11	0.05	lasso	3	0.02	7.8e-03	7.28	7.6	4.1e-14	-0.11	0.51	0.02	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DLEU7	0.05	0.00	blup	581	0.02	1.6e-03	1.30	6.8	8.5e-12	-0.46	0.08	0.21	TRUE
12	GTEx	Pancreas	EBPL	0.18	0.10	enet	5	0.09	1.6e-04	7.36	-6.2	4.8e-10	0.07	0.38	0.04	TRUE
13	GTEx	Pituitary	EBPL	0.44	0.32	enet	29	0.37	3.1e-10	6.45	-6.0	2.3e-09	-0.02	0.92	0.01	TRUE
18	GTEx	Thyroid	EBPL	0.36	0.14	enet	33	0.30	5.1e-23	6.34	-6.0	2.3e-09	0.08	1.00	0.00	TRUE
6	GTEx	Brain Cortex	EBPL	0.36	0.08	enet	24	0.14	1.5e-04	7.36	-5.6	2.0e-08	0.14	0.18	0.15	TRUE
2	CommonMind	Brain Pre-frontal Cortex	EBPL	0.34	0.16	bslmm	399	0.33	2.5e-41	0.12	-5.6	2.1e-08	0.04	1.00	0.00	TRUE
23	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EBPL	0.27	0.16	blup	59	0.22	1.0e-12	-0.92	-5.3	1.0e-07	0.06	0.29	0.71	TRUE
17	GTEx	Testis	EBPL	0.33	0.17	lasso	6	0.24	8.4e-11	6.49	-7.3	2.5e-13	0.03	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM13	0.04	0.00	blup	26	0.02	8.5e-03	7.32	-7.1	1.0e-12	0.06	0.00	0.46	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DLEU2	0.03	0.01	blup	61	0.02	2.4e-03	7.19	6.9	4.1e-12	-0.10	0.01	0.96	FALSE
15	GTEx	Skin Sun Exposed Lower leg	EBPL	0.28	0.21	lasso	5	0.20	2.5e-16	6.77	-6.9	6.1e-12	0.02	1.00	0.00	FALSE
5	GTEx	Brain Cerebellum	EBPL	0.50	0.30	enet	23	0.36	1.8e-11	7.36	-6.5	1.0e-10	0.05	0.86	0.01	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	EBPL	0.27	0.24	enet	14	0.26	4.6e-10	6.34	-6.5	1.1e-10	0.02	1.00	0.00	FALSE
14	GTEx	Skin Not Sun Exposed Suprapubic	EBPL	0.34	0.26	enet	12	0.30	4.0e-17	6.45	-6.1	9.3e-10	0.00	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EBPL	0.21	0.09	enet	10	0.13	4.9e-06	7.36	-6.0	1.7e-09	0.07	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EBPL	0.28	0.18	blup	59	0.19	4.3e-08	6.46	-6.0	2.1e-09	0.06	0.01	0.98	FALSE
3	GTEx	Artery Aorta	EBPL	0.43	0.20	enet	78	0.28	8.1e-16	6.45	-5.8	5.8e-09	0.14	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	EBPL	0.39	0.16	enet	36	0.29	9.2e-18	6.45	-5.8	8.2e-09	0.03	1.00	0.00	FALSE
7	GTEx	Brain Nucleus accumbens basal ganglia	EBPL	0.25	0.11	enet	21	0.11	7.9e-04	6.46	-5.6	2.2e-08	0.12	0.13	0.09	FALSE
21	ROSMAP	Brain Pre-frontal Cortex	EBPL	0.43	0.28	lasso	8	0.43	7.3e-60	6.34	-5.6	2.4e-08	0.03	1.00	0.00	FALSE
4	GTEx	Brain Caudate basal ganglia	EBPL	0.41	0.06	lasso	7	0.12	2.1e-04	6.34	-5.6	2.8e-08	0.02	0.11	0.17	FALSE
16	GTEx	Spleen	RCBTB1	0.37	0.02	lasso	5	0.04	3.5e-02	-0.24	-5.5	4.3e-08	0.01	0.04	0.10	FALSE
8	GTEx	Brain Putamen basal ganglia	EBPL	0.31	-0.01	enet	18	0.05	2.9e-02	6.46	-5.4	6.2e-08	0.08	0.06	0.13	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	EBPL	0.08	0.01	blup	59	0.04	6.4e-05	6.46	-5.4	6.6e-08	0.04	0.01	0.89	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DLEU2	0.08	0.02	lasso	2	0.01	1.6e-02	-4.96	5.2	1.7e-07	0.02	0.13	0.21	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	EBPL	0.28	0.10	enet	17	0.26	7.7e-25	-0.92	-5.2	1.9e-07	0.02	0.24	0.76	FALSE
19	METSIM	Adipose	EBPL	0.32	0.12	lasso	7	0.27	1.4e-39	6.49	-5.2	2.2e-07	0.03	1.00	0.00	FALSE