Best TWAS P=4.8e-19 · Best GWAS P=7.45e-19 conditioned to 0.288
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -7.6 | 7.9 | 3.0e-15 | -0.61 | 0.4 | 0.58 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -8.9 | 8.9 | 4.8e-19 | -0.90 | 0.0 | 0.77 | TRUE |