[Hub]/) : Traits : Leg fat-free mass (right) :

chr13:114,302,502-115,106,996

Best TWAS P=5.18e-09 · Best GWAS P=1.95e-07 conditioned to 0.138

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum CDC16 0.18 0.05 lasso 4 0.07 3.4e-03 -5.0 -5.1 2.9e-07 0.71 0.02 0.94 FALSE
2 GTEx Breast Mammary Tissue CDC16 0.25 0.28 lasso 6 0.26 6.9e-14 -5.1 -5.4 8.0e-08 0.71 0.02 0.98 FALSE
3 GTEx Breast Mammary Tissue (Male) CDC16 0.23 0.08 enet 11 0.09 3.8e-03 -4.6 -5.6 2.1e-08 0.71 0.04 0.82 FALSE
4 GTEx Breast Mammary Tissue (Female) CDC16 0.25 0.22 enet 28 0.22 3.6e-07 -5.1 -5.3 1.3e-07 0.71 0.02 0.98 FALSE
5 GTEx Cells Transformed fibroblasts CDC16 0.17 0.13 lasso 6 0.15 4.6e-11 -5.0 -5.1 2.9e-07 0.79 0.02 0.98 FALSE
6 GTEx Colon Transverse CDC16 0.18 0.23 lasso 5 0.21 3.2e-10 -5.1 -5.3 1.5e-07 0.78 0.02 0.98 FALSE
7 GTEx Esophagus Gastroesophageal Junction CDC16 0.09 0.05 lasso 2 0.02 5.7e-02 -5.1 -5.2 2.3e-07 0.75 0.02 0.88 FALSE
8 GTEx Nerve Tibial CDC16 0.23 0.23 enet 19 0.26 9.5e-19 -5.1 -5.3 1.5e-07 0.80 0.01 0.98 FALSE
9 GTEx Pancreas CDC16 0.09 0.14 lasso 3 0.06 1.8e-03 -5.1 -5.1 3.0e-07 0.75 0.02 0.96 FALSE
10 GTEx Prostate CDC16 0.17 0.16 lasso 3 0.11 1.4e-03 -5.1 -5.1 3.1e-07 0.75 0.02 0.92 FALSE
11 GTEx Skin Sun Exposed Lower leg CDC16 0.31 0.33 lasso 7 0.33 4.1e-28 -5.0 -5.2 1.9e-07 0.77 0.02 0.98 FALSE
12 GTEx Testis CDC16 0.32 0.30 enet 26 0.35 4.4e-16 -5.1 -5.8 5.2e-09 0.71 0.01 0.98 TRUE
13 The Cancer Genome Atlas Colon Adenocarcinoma CDC16 0.06 0.04 lasso 5 0.03 5.9e-03 -5.2 -5.5 3.4e-08 0.97 0.01 0.91 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDC16 0.05 0.04 blup 49 0.05 2.0e-06 -5.1 -5.1 3.0e-07 0.84 0.02 0.98 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma CDC16 0.04 0.01 blup 49 0.03 7.7e-03 -5.1 -5.2 2.3e-07 0.72 0.02 0.93 FALSE
16 The Cancer Genome Atlas Pancreatic Adenocarcinoma CDC16 0.11 0.09 blup 49 0.09 1.8e-04 -5.1 -5.5 5.0e-08 0.76 0.02 0.96 FALSE
17 The Cancer Genome Atlas Thyroid Carcinoma CDC16 0.06 0.09 lasso 3 0.09 3.3e-09 -5.1 -5.4 6.4e-08 0.82 0.01 0.99 FALSE