[Hub]/) : Traits : Leg fat-free mass (right) :

chr14:20,843,889-22,662,856

Best TWAS P=3.02e-09 · Best GWAS P=5.2e-10 conditioned to 3.39e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARHGEF40 0.34 0.32 enet 17 0.31 1.5e-17 -5.7 -5.5 5.0e-08 0.06 0.02 0.98 TRUE
2 GTEx Testis TOX4 0.31 0.00 enet 24 0.04 6.8e-03 -5.7 -5.9 3.0e-09 -0.49 0.03 0.63 TRUE
3 The Cancer Genome Atlas Breast Invasive Carcinoma METTL3 0.03 0.04 lasso 1 0.04 3.1e-08 -5.6 -5.6 2.3e-08 -0.19 0.04 0.96 FALSE
4 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma METTL3 0.04 0.04 lasso 2 0.04 2.5e-05 -5.7 -5.7 1.3e-08 -0.20 0.03 0.94 FALSE
5 The Cancer Genome Atlas Testicular Germ Cell Tumors METTL3 0.17 0.03 lasso 2 0.04 1.5e-02 -5.7 -5.8 5.2e-09 -0.29 0.02 0.51 FALSE