[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr16:14,229,099-15,886,243

Best TWAS P=1.05e-12 · Best GWAS P=2.44e-10 conditioned to 0.517

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NTAN1 0.05 0.03 lasso 2 0.04 6.7e-04 -6.3 6.6 3.1e-11 -0.93 0.01 0.97 FALSE
2 GTEx Artery Tibial RRN3 0.11 0.06 lasso 2 0.07 2.0e-06 5.3 5.2 2.6e-07 -0.49 0.66 0.32 FALSE
3 GTEx Cells EBV-transformed lymphocytes RRN3 0.36 0.14 lasso 5 0.20 4.5e-07 5.3 5.6 2.5e-08 -0.60 0.18 0.78 FALSE
4 GTEx Cells Transformed fibroblasts RRN3 0.10 0.12 enet 13 0.13 6.3e-10 5.3 6.0 1.7e-09 -0.59 0.56 0.44 FALSE
5 GTEx Heart Atrial Appendage NOMO1 0.19 0.12 lasso 6 0.10 3.7e-05 5.2 5.1 2.7e-07 -0.48 0.21 0.30 FALSE
6 GTEx Heart Atrial Appendage NTAN1 0.10 0.09 lasso 1 0.07 3.7e-04 5.2 5.2 2.3e-07 -0.49 0.04 0.44 FALSE
7 GTEx Heart Left Ventricle RRN3 0.24 0.12 lasso 7 0.17 2.2e-09 5.2 -6.0 2.5e-09 0.39 0.49 0.43 FALSE
8 GTEx Heart Left Ventricle NTAN1 0.09 0.04 lasso 3 0.02 2.0e-02 5.3 5.2 2.1e-07 -0.48 0.02 0.71 FALSE
9 GTEx Muscle Skeletal RRN3 0.18 0.03 enet 17 0.11 5.7e-11 4.0 -5.2 1.5e-07 0.37 0.17 0.70 FALSE
10 GTEx Muscle Skeletal NTAN1 0.12 0.07 lasso 6 0.09 1.4e-09 5.2 5.6 1.8e-08 -0.46 0.70 0.30 FALSE
11 GTEx Nerve Tibial NTAN1 0.07 0.00 enet 14 0.00 1.7e-01 5.3 5.8 7.2e-09 -0.17 0.02 0.18 FALSE
12 GTEx Skin Sun Exposed Lower leg RRN3 0.10 0.12 lasso 1 0.11 4.5e-09 5.3 5.3 1.0e-07 -0.48 0.65 0.35 FALSE
13 GTEx Testis RRN3 0.10 0.10 lasso 2 0.07 3.9e-04 5.3 5.3 1.0e-07 -0.48 0.11 0.17 FALSE
14 NTR Blood NTAN1 0.01 0.00 bslmm 110 0.00 4.2e-02 5.3 5.7 1.5e-08 -0.23 0.02 0.04 FALSE
15 NTR Blood PDXDC1 0.12 0.12 enet 26 0.15 1.3e-46 -6.2 7.1 1.0e-12 -0.84 0.01 0.99 TRUE
16 ROSMAP Brain Pre-frontal Cortex NTAN1 0.12 0.10 lasso 3 0.11 1.4e-13 5.2 5.2 2.0e-07 -0.48 0.74 0.26 FALSE