[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr16:14,229,099-15,886,243

Best TWAS P=1.05e-12 · Best GWAS P=2.44e-10 conditioned to 0.517

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	NTR	Blood	PDXDC1	0.12	0.12	enet	26	0.15	1.3e-46	-6.2	7.1	1.0e-12	-0.84	0.01	0.99	TRUE
1	GTEx	Adipose Subcutaneous	NTAN1	0.05	0.03	lasso	2	0.04	6.7e-04	-6.3	6.6	3.1e-11	-0.93	0.01	0.97	FALSE
4	GTEx	Cells Transformed fibroblasts	RRN3	0.10	0.12	enet	13	0.13	6.3e-10	5.3	6.0	1.7e-09	-0.59	0.56	0.44	FALSE
7	GTEx	Heart Left Ventricle	RRN3	0.24	0.12	lasso	7	0.17	2.2e-09	5.2	-6.0	2.5e-09	0.39	0.49	0.43	FALSE
11	GTEx	Nerve Tibial	NTAN1	0.07	0.00	enet	14	0.00	1.7e-01	5.3	5.8	7.2e-09	-0.17	0.02	0.18	FALSE
14	NTR	Blood	NTAN1	0.01	0.00	bslmm	110	0.00	4.2e-02	5.3	5.7	1.5e-08	-0.23	0.02	0.04	FALSE
10	GTEx	Muscle Skeletal	NTAN1	0.12	0.07	lasso	6	0.09	1.4e-09	5.2	5.6	1.8e-08	-0.46	0.70	0.30	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	RRN3	0.36	0.14	lasso	5	0.20	4.5e-07	5.3	5.6	2.5e-08	-0.60	0.18	0.78	FALSE
12	GTEx	Skin Sun Exposed Lower leg	RRN3	0.10	0.12	lasso	1	0.11	4.5e-09	5.3	5.3	1.0e-07	-0.48	0.65	0.35	FALSE
13	GTEx	Testis	RRN3	0.10	0.10	lasso	2	0.07	3.9e-04	5.3	5.3	1.0e-07	-0.48	0.11	0.17	FALSE
9	GTEx	Muscle Skeletal	RRN3	0.18	0.03	enet	17	0.11	5.7e-11	4.0	-5.2	1.5e-07	0.37	0.17	0.70	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	NTAN1	0.12	0.10	lasso	3	0.11	1.4e-13	5.2	5.2	2.0e-07	-0.48	0.74	0.26	FALSE
8	GTEx	Heart Left Ventricle	NTAN1	0.09	0.04	lasso	3	0.02	2.0e-02	5.3	5.2	2.1e-07	-0.48	0.02	0.71	FALSE
6	GTEx	Heart Atrial Appendage	NTAN1	0.10	0.09	lasso	1	0.07	3.7e-04	5.2	5.2	2.3e-07	-0.49	0.04	0.44	FALSE
2	GTEx	Artery Tibial	RRN3	0.11	0.06	lasso	2	0.07	2.0e-06	5.3	5.2	2.6e-07	-0.49	0.66	0.32	FALSE
5	GTEx	Heart Atrial Appendage	NOMO1	0.19	0.12	lasso	6	0.10	3.7e-05	5.2	5.1	2.7e-07	-0.48	0.21	0.30	FALSE