[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr16:71,070,698-72,540,539

Best TWAS P=1.37e-10 · Best GWAS P=7.55e-13 conditioned to 6.98e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MARVELD3 0.07 0.05 lasso 3 0.09 5.7e-11 -6.3 -5.6 1.9e-08 0.43 0.51 0.49 FALSE
2 CommonMind Brain Pre-frontal Cortex PHLPP2 0.04 0.01 bslmm 456 0.02 4.7e-04 -5.0 -6.4 1.4e-10 0.41 0.43 0.47 TRUE
3 GTEx Adrenal Gland AP1G1 0.22 0.06 enet 25 0.14 8.0e-06 -6.2 -6.1 8.1e-10 0.46 0.34 0.59 FALSE
4 GTEx Artery Aorta AP1G1 0.10 0.09 lasso 2 0.07 1.3e-04 -5.2 -5.2 2.5e-07 0.43 0.39 0.28 FALSE
5 GTEx Artery Tibial AP1G1 0.07 0.06 lasso 6 0.06 1.0e-05 -3.4 -5.3 1.4e-07 0.51 0.60 0.39 FALSE
6 GTEx Testis PHLPP2 0.29 0.38 enet 20 0.37 3.0e-17 -6.3 6.2 7.5e-10 -0.56 0.48 0.52 FALSE
7 YFS Blood PHLPP2 0.04 0.03 bslmm 459 0.05 5.5e-16 -6.2 5.6 2.8e-08 -0.42 0.53 0.47 FALSE
8 The Cancer Genome Atlas Esophageal Carcinoma PHLPP2 0.18 0.03 blup 67 0.07 2.9e-03 -6.3 -5.5 4.6e-08 0.46 0.06 0.12 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma AP1G1 0.03 0.03 lasso 4 0.02 2.1e-03 -3.4 -5.1 2.8e-07 0.46 0.02 0.86 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma AP1G1 0.11 0.02 enet 27 0.04 1.2e-04 3.0 -5.4 5.9e-08 0.41 0.08 0.24 FALSE