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chr16:71,070,698-72,540,539

Best TWAS P=1.37e-10 · Best GWAS P=7.55e-13 conditioned to 6.98e-07

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	CommonMind	Brain Pre-frontal Cortex	PHLPP2	0.04	0.01	bslmm	456	0.02	4.7e-04	-5.0	-6.4	1.4e-10	0.41	0.43	0.47	TRUE
6	GTEx	Testis	PHLPP2	0.29	0.38	enet	20	0.37	3.0e-17	-6.3	6.2	7.5e-10	-0.56	0.48	0.52	FALSE
3	GTEx	Adrenal Gland	AP1G1	0.22	0.06	enet	25	0.14	8.0e-06	-6.2	-6.1	8.1e-10	0.46	0.34	0.59	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MARVELD3	0.07	0.05	lasso	3	0.09	5.7e-11	-6.3	-5.6	1.9e-08	0.43	0.51	0.49	FALSE
7	YFS	Blood	PHLPP2	0.04	0.03	bslmm	459	0.05	5.5e-16	-6.2	5.6	2.8e-08	-0.42	0.53	0.47	FALSE
8	The Cancer Genome Atlas	Esophageal Carcinoma	PHLPP2	0.18	0.03	blup	67	0.07	2.9e-03	-6.3	-5.5	4.6e-08	0.46	0.06	0.12	FALSE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	AP1G1	0.11	0.02	enet	27	0.04	1.2e-04	3.0	-5.4	5.9e-08	0.41	0.08	0.24	FALSE
5	GTEx	Artery Tibial	AP1G1	0.07	0.06	lasso	6	0.06	1.0e-05	-3.4	-5.3	1.4e-07	0.51	0.60	0.39	FALSE
4	GTEx	Artery Aorta	AP1G1	0.10	0.09	lasso	2	0.07	1.3e-04	-5.2	-5.2	2.5e-07	0.43	0.39	0.28	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	AP1G1	0.03	0.03	lasso	4	0.02	2.1e-03	-3.4	-5.1	2.8e-07	0.46	0.02	0.86	FALSE