TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Leg fat-free mass (right)
:
←
→
chr16:67,423,939-68,988,905
Best TWAS P=4.71e-08 · Best GWAS P=1.02e-09 conditioned to 4.33e-06
67.4M
67.6M
67.8M
68M
68.2M
68.4M
68.6M
68.8M
69M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Lung
NFATC3
0.04
0.01
lasso
4
0.01
4.1e-02
5.1
-5.5
4.7e-08
-0.32
0.18
0.46
TRUE
2
GTEx
Thyroid
PLA2G15
0.06
0.04
enet
5
0.04
5.7e-04
5.6
5.3
9.2e-08
0.38
0.10
0.87
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
NFATC3
0.11
0.04
enet
4
0.04
2.8e-05
5.4
-5.3
1.3e-07
-0.36
0.00
0.99
FALSE