[Hub]/) : Traits : Leg fat-free mass (right) :

chr19:41,233,298-42,626,207

Best TWAS P=1.05e-09 · Best GWAS P=4.66e-08 conditioned to 0.544

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTC-435M10.6 0.16 0.14 lasso 3 0.13 1.3e-07 5.3 5.2 2.2e-07 0.99 0.02 0.98 FALSE
2 GTEx Brain Cerebellar Hemisphere B3GNT8 0.38 0.30 lasso 5 0.23 1.1e-06 5.5 5.3 1.4e-07 0.99 0.01 0.98 FALSE
3 GTEx Brain Cerebellar Hemisphere CTC-435M10.6 0.29 0.20 lasso 4 0.18 2.6e-05 5.5 5.5 3.6e-08 1.00 0.01 0.96 FALSE
4 GTEx Brain Cerebellum B3GNT8 0.28 0.23 lasso 5 0.21 9.2e-07 5.5 5.3 1.2e-07 0.99 0.02 0.98 FALSE
5 GTEx Brain Cerebellum CTC-435M10.6 0.18 0.01 lasso 4 0.03 5.1e-02 5.2 5.5 2.9e-08 0.86 0.02 0.85 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma EXOSC5 0.04 0.03 lasso 2 0.02 5.8e-03 5.5 5.4 5.7e-08 0.98 0.01 0.79 FALSE
7 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ATP5SL 0.23 0.05 blup 18 0.05 4.5e-03 5.4 -6.0 2.7e-09 -0.90 0.01 0.83 FALSE
8 The Cancer Genome Atlas Prostate Adenocarcinoma ATP5SL 0.03 0.03 blup 18 0.03 4.1e-04 5.4 -5.2 1.8e-07 -0.98 0.01 0.92 FALSE
9 The Cancer Genome Atlas Rectum Adenocarcinoma B3GNT8 0.39 0.08 blup 20 0.07 1.1e-02 5.1 6.1 1.1e-09 0.84 0.00 0.28 TRUE