TWAS hub - ATP5SL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3360	0.0410	0.0e+00	0.478	0.435	0.468	0.477	0.474	1.1e-65	5.4e-58	5.8e-64	1.5e-65	4.6e-65
2	GTEx	Artery Aorta	0.1420	0.0640	5.2e-03	-0.004	NA	-0.005	NA	0.005	6.7e-01	NA	7.2e-01	NA	1.6e-01
3	GTEx	Brain Frontal Cortex BA9	0.2789	0.1090	9.9e-03	0.154	NA	0.028	NA	0.105	7.2e-05	NA	6.1e-02	NA	1.0e-03
4	GTEx	Brain Hypothalamus	0.5780	0.1360	5.8e-03	-0.002	NA	0.001	NA	0.000	3.5e-01	NA	3.1e-01	NA	3.3e-01
5	GTEx	Nerve Tibial	0.0910	0.0401	6.5e-03	0.038	NA	0.018	NA	0.044	1.1e-03	NA	1.9e-02	NA	4.2e-04
6	NTR	Blood	0.0176	0.0081	4.1e-03	0.002	0.007	0.003	0.007	0.003	8.0e-02	2.1e-03	2.9e-02	2.0e-03	3.4e-02
7	YFS	Blood	0.0583	0.0171	6.1e-10	0.024	0.027	0.028	NA	0.028	2.3e-08	2.3e-09	1.8e-09	NA	1.1e-09
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0369	0.0312	9.6e-05	0.030	0.030	0.032	NA	0.028	2.4e-04	2.1e-04	1.6e-04	NA	4.0e-04
9	TCGA	Brain Lower Grade Glioma	0.0229	0.0174	7.3e-04	0.026	0.023	0.025	NA	0.023	5.5e-04	1.0e-03	7.0e-04	NA	1.0e-03
10	TCGA	Pheochromocytoma and Paraganglioma	0.2280	0.1620	6.4e-04	0.051	0.051	0.033	NA	0.047	4.2e-03	4.5e-03	1.9e-02	NA	6.2e-03
11	TCGA	Prostate Adenocarcinoma	0.0257	0.0211	1.1e-03	0.031	0.030	0.003	NA	0.029	3.2e-04	4.1e-04	1.5e-01	NA	4.9e-04
12	TCGA	Thyroid Carcinoma	0.0230	0.0200	4.3e-03	0.021	0.021	0.014	NA	0.019	3.7e-03	3.5e-03	1.4e-02	NA	5.8e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Hair/balding pattern: Pattern 4	15.8	38.2	52.3	6.8	6.8	7.2	1.7	-1.7	-4.2	-6.8	6.5	7.1	7.2	7.2	7.0
Height	10.3	198.2	309.8	-15.8	-16.1	-16.2	-5.5	3.2	7.1	14.6	-14.0	-16.2	-17.6	-16.6	-16.1
Standing height	10.3	101.7	158.8	-11.4	-11.3	-11.4	-4.8	2.8	4.7	10.9	-10.2	-11.5	-12.6	-11.7	-11.4
Comparative height size at age 10	10.2	56.2	82.8	-8.4	-8.3	-8.5	-3.5	2.2	3.4	8.1	-7.9	-8.6	-9.1	-8.7	-8.5
Sitting height	7.9	56.3	77.9	-8.5	-8.5	-8.4	-2.6	2.5	4.3	8.3	-7.9	-8.6	-8.8	-8.7	-8.4
Alcohol drinker status: Never	6.7	8.0	12.0	-3.3	-3.1	-3.4	-1.2	0.7	1.7	2.8	-3.1	-3.1	-3.5	-3.3	-3.2
Headache pain in last month	6.3	10.8	16.2	4.0	3.8	3.7	1.1	-0.7	-2.1	-3.5	3.4	3.8	3.5	3.8	3.8
Prostate Cancer	5.6	7.9	20.6	2.2	2.6	2.6	0.4	-4.5	-0.8	-4.3	2.7	2.6	2.9	2.7	2.5
Hair/balding pattern: Pattern 3	5.3	7.9	14.0	2.9	3.1	3.2	1.7	-0.8	-1.2	-2.7	2.7	3.2	3.7	3.3	3.2
Trunk fat-free mass	5.0	28.5	45.6	-6.0	-5.8	-5.9	-3.2	1.8	1.5	5.9	-5.6	-6.0	-6.8	-6.1	-6.0
Trunk predicted mass	4.9	28.2	44.9	-6.0	-5.8	-5.9	-3.3	1.8	1.4	5.9	-5.5	-6.0	-6.7	-6.1	-6.0
Ever unenthusiastic/disinterested for a whole week	4.8	5.9	9.7	-3.1	-2.5	-2.7	-2.5	0.7	-0.3	2.3	-3.0	-2.6	-2.3	-2.6	-2.8
Whole body fat-free mass	4.5	25.8	42.4	-5.7	-5.6	-5.6	-3.2	1.6	1.4	5.6	-5.2	-5.7	-6.5	-5.8	-5.7
Basal metabolic rate	4.3	23.9	37.9	-5.4	-5.4	-5.4	-2.8	1.7	1.3	5.5	-5.0	-5.5	-6.2	-5.6	-5.5
Whole body water mass	4.2	23.8	38.4	-5.5	-5.4	-5.4	-3.0	1.5	1.3	5.4	-5.0	-5.5	-6.2	-5.6	-5.5
Leg fat-free mass (left)	3.9	20.9	35.6	-5.1	-5.1	-5.0	-2.8	1.3	1.4	5.0	-4.6	-5.2	-6.0	-5.3	-5.2
Leg predicted mass (left)	3.9	20.8	35.3	-5.0	-5.1	-5.0	-2.8	1.4	1.4	4.9	-4.6	-5.2	-5.9	-5.3	-5.2
Leg predicted mass (right)	3.9	20.6	35.7	-5.1	-5.0	-5.0	-2.6	1.2	1.3	4.9	-4.6	-5.1	-6.0	-5.3	-5.1
Heart disease (siblings)	3.9	4.8	6.8	-2.5	-2.3	-2.5	-2.1	-1.0	1.8	1.7	-2.6	-2.4	-1.9	-2.4	-2.5
Leg fat-free mass (right)	3.8	20.4	35.4	-5.0	-5.0	-5.0	-2.6	1.2	1.4	4.9	-4.6	-5.1	-6.0	-5.2	-5.1
Medication: Paracetamol	3.7	5.6	8.9	2.9	2.7	2.8	1.0	0.1	-1.8	-1.8	3.0	2.8	2.1	2.7	2.9
Myopia	3.6	5.2	16.1	-2.2	-2.2	-2.2	-0.6	1.1	4.0	2.2	-2.1	-2.1	-2.6	-2.3	-2.1
Pulse rate, automated reading	3.4	10.8	17.3	3.9	3.8	3.8	1.7	-0.2	-1.1	-3.3	3.2	3.8	4.2	3.9	3.7
Medication: Paracetamol	3.3	5.4	9.1	2.7	2.7	2.7	1.1	-0.3	-1.6	-2.1	3.0	2.8	1.8	2.7	2.8
Arm fat-free mass (left)	3.3	16.9	24.1	-4.6	-4.5	-4.5	-2.4	1.1	1.0	4.7	-4.5	-4.7	-4.9	-4.7	-4.7
Emphysema/chronic bronchitis	3.2	3.6	5.3	-2.3	-2.1	-2.2	-0.4	-0.9	1.9	1.4	-2.2	-2.1	-1.9	-2.2	-2.3
Arm predicted mass (left)	3.2	16.3	22.8	-4.5	-4.5	-4.5	-2.5	1.0	0.9	4.6	-4.4	-4.6	-4.8	-4.6	-4.6
Bilateral oophorectomy (both ovaries removed)	3.1	3.6	7.3	-2.0	-1.8	-2.2	-0.1	1.2	-0.1	2.4	-2.7	-2.0	-2.1	-2.1	-2.0
Hearing difficulty/problems with background noise	3.1	5.0	8.3	2.4	2.5	2.7	2.2	0.0	0.4	-1.8	2.9	2.5	2.0	2.6	2.5
Weight	2.9	14.0	22.1	-4.2	-4.1	-4.2	-1.7	1.2	1.1	4.5	-3.8	-4.2	-4.7	-4.3	-4.3
Illnesses of siblings	2.8	3.9	6.3	2.4	2.5	2.3	0.8	0.8	-0.8	-1.6	1.7	2.3	2.4	2.4	2.4
Arm fat-free mass (right)	2.8	14.2	21.2	-4.1	-4.1	-4.1	-2.2	1.4	0.8	4.4	-4.1	-4.3	-4.6	-4.3	-4.3
Migraine (self-reported)	2.8	3.5	5.8	2.1	1.9	1.9	-1.4	-0.3	-2.1	-1.8	1.6	2.0	2.4	2.0	2.0
Heel bone mineral density (BMD) T-score, automated (right)	2.7	6.2	8.8	2.5	2.8	3.0	-0.9	-0.5	-1.5	-2.9	2.9	2.9	2.7	2.9	2.8
Forced vital capacity (FVC), Best measure	2.7	10.0	21.0	-3.5	-3.5	-3.6	-2.4	0.7	0.6	3.0	-2.7	-3.5	-4.6	-3.7	-3.6
Arm predicted mass (right)	2.7	13.7	19.9	-4.1	-4.1	-4.1	-1.9	1.0	1.0	4.3	-4.0	-4.2	-4.5	-4.3	-4.2
Supplements: Fish oil (including cod liver oil)	2.7	3.5	6.2	2.1	1.9	2.1	1.9	-0.6	-0.9	-2.1	2.5	2.1	0.9	1.9	2.1
Coronary Artery Disease (CAD)	2.6	3.1	4.8	-2.1	-2.1	-2.1	-0.4	0.8	1.1	1.7	-1.7	-2.2	-1.6	-2.0	-2.1
Eye problems/disorders: Glaucoma	2.6	3.0	4.5	1.8	2.1	2.1	-0.1	-1.0	-1.3	-1.7	1.6	2.1	1.9	2.1	2.1
Mouth/teeth dental problems: Mouth ulcers	2.4	3.8	6.3	-2.3	-2.1	-2.3	-0.6	0.3	1.2	2.2	-1.9	-2.2	-2.5	-2.2	-2.1
Forced vital capacity (FVC)	2.3	8.8	18.3	-3.4	-3.4	-3.3	-1.7	0.8	-0.1	3.0	-2.5	-3.4	-4.3	-3.5	-3.3
Qualifications: None of the above	2.3	4.9	7.7	-2.3	-2.8	-2.7	-0.0	-1.0	1.5	1.9	-1.8	-2.7	-2.4	-2.7	-2.8
Heart attack	2.2	2.8	6.3	-1.4	-1.7	-1.7	0.2	1.9	-1.2	1.8	-2.5	-1.7	-1.6	-1.8	-1.6
Diastolic blood pressure, automated reading	2.1	6.4	9.8	3.1	2.7	2.7	0.3	0.6	-1.8	-2.2	3.1	2.8	3.1	2.9	2.8
Hip circumference	2.0	8.5	15.5	-3.2	-3.1	-3.2	-0.9	1.2	1.3	3.9	-2.6	-3.3	-3.7	-3.3	-3.3
Ever taken oral contraceptive pill	2.0	2.2	4.0	-1.8	-1.4	-1.4	0.9	0.9	1.7	2.0	-1.0	-1.4	-1.6	-1.5	-1.6
HbA1C	1.9	2.1	5.8	1.4	1.3	1.4	1.0	1.7	-1.8	-0.6	2.4	1.3	0.7	1.4	1.5
Had other major operations	1.9	2.4	4.3	-1.7	-1.6	-1.6	-1.4	1.3	-0.9	2.1	-1.3	-1.5	-1.6	-1.6	-1.6
Mouth/teeth dental problems	1.9	2.8	7.8	1.6	1.7	1.8	-0.9	-0.3	-1.4	-1.7	1.5	1.8	2.8	1.9	1.7
Glaucoma (self-reported)	1.9	2.2	3.3	1.6	1.7	1.7	0.3	-1.0	-0.3	-1.8	1.5	1.8	1.4	1.7	1.8
Chronic bronchitis/emphysema (mother)	1.9	2.2	3.9	1.9	2.0	1.7	0.2	0.6	-1.4	-0.9	1.4	1.6	1.4	1.7	1.8
Medication: Ibuprofen	1.9	2.3	3.8	1.7	1.4	1.8	1.4	-1.3	-0.6	-1.8	2.0	1.6	0.9	1.5	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	3.4	1.6	1.8	1.8	1.4	0.2	-1.6	-1.1	0.9	1.8	1.4	1.7	1.8
Mineral and other dietary supplements	1.9	2.6	4.5	-1.8	-1.8	-1.8	-1.3	0.9	0.3	1.9	-2.1	-1.8	-1.0	-1.7	-1.8
Heel T-Score	1.8	14.4	33.8	3.7	4.5	4.3	0.7	-0.8	-2.1	-3.2	3.3	4.5	5.8	4.7	4.1
Trunk fat mass	1.8	7.8	12.4	-3.0	-3.1	-3.1	-0.1	1.0	1.2	3.5	-2.5	-3.2	-3.5	-3.3	-3.2
Impedance of arm (right)	1.8	8.2	14.3	-3.3	-3.3	-3.3	-0.7	-0.1	2.4	2.5	-2.3	-3.3	-3.8	-3.4	-3.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.8	5.6	13.7	-2.7	-2.6	-2.7	-1.8	0.1	0.4	2.0	-1.8	-2.6	-3.7	-2.8	-2.7
Exposure to tobacco smoke outside home	1.8	2.4	3.3	1.8	1.3	1.7	1.0	-0.9	-1.8	-1.8	1.8	1.5	1.7	1.5	1.4
Leg pain on walking	1.8	2.2	5.4	-1.5	-1.3	-1.4	-2.0	0.4	2.3	1.7	-1.8	-1.3	-0.5	-1.3	-1.4
Smoking status: Previous	1.8	2.7	7.8	-1.1	-1.6	-1.6	0.5	2.6	-0.9	2.8	-1.3	-1.5	-1.1	-1.5	-1.6
Breast cancer (self-reported)	1.8	2.1	3.3	-1.8	-1.8	-1.7	-0.1	0.3	0.9	1.6	-1.2	-1.6	-1.6	-1.7	-1.6
Mean Putamen Volume	1.7	2.0	3.2	-1.3	-1.5	-1.6	1.8	-0.8	0.2	1.1	-1.7	-1.5	-1.6	-1.5	-1.4
Pulse rate	1.7	2.9	6.9	2.3	2.0	1.9	0.1	0.5	-0.4	-1.6	1.1	1.9	2.6	2.0	1.9
Qualifications: College or University degree	1.7	5.4	8.2	2.5	2.9	2.6	-1.0	0.9	-2.3	-2.0	2.1	2.8	2.3	2.7	2.7
Medication for pain relief, constipation, heartburn	1.7	2.9	4.1	-1.9	-1.9	-1.9	-1.2	0.6	1.2	1.8	-2.0	-2.0	-1.3	-1.9	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.5	5.2	-2.1	-1.9	-2.1	-1.7	0.0	-0.0	2.0	-2.3	-2.0	-2.2	-2.1	-2.0
Heart attack/myocardial infarction (self-reported)	1.7	2.2	5.7	-1.1	-1.4	-1.4	0.5	1.9	-1.2	1.5	-2.4	-1.5	-1.2	-1.5	-1.3
Type 2 Diabetes (T2D) (2012)	1.6	1.9	3.1	1.5	1.3	1.5	0.4	-0.9	-1.8	-1.4	1.0	1.4	1.8	1.5	1.5
Number of treatments/medications taken	1.6	3.0	9.4	1.6	1.7	1.9	0.8	0.1	-3.1	-1.1	2.0	1.8	1.6	1.8	1.8
Forced expiratory volume in 1-second (FEV1)	1.6	5.4	13.2	-2.7	-2.7	-2.5	-1.2	0.5	0.2	2.1	-1.8	-2.6	-3.6	-2.8	-2.6
Loud music exposure frequency	1.6	1.7	2.3	-1.3	-1.5	-1.3	0.8	0.6	1.2	1.5	-1.2	-1.5	-1.5	-1.5	-1.5
Heart disease (mother)	1.6	2.0	2.9	-1.4	-1.5	-1.7	0.0	0.3	1.6	1.7	-1.6	-1.6	-0.8	-1.6	-1.6
Ever smoked	1.6	2.8	4.7	1.8	1.5	1.7	0.8	2.2	-1.8	-0.3	2.2	1.7	1.8	1.7	1.6
Ever had hysterectomy (womb removed)	1.5	1.7	3.9	-1.7	-1.3	-1.5	0.9	0.6	0.0	1.5	-2.0	-1.3	-0.8	-1.3	-1.4
Medication: Metformin	1.5	2.2	7.7	1.4	1.7	1.6	0.3	0.7	-1.4	-0.5	0.4	1.6	2.8	1.7	1.5
Medication: Atenolol	1.5	1.9	2.8	-1.5	-1.7	-1.6	1.2	0.6	-0.3	1.7	-1.6	-1.6	-0.9	-1.6	-1.5
Prospective memory result	1.5	1.8	3.5	1.7	1.3	1.4	1.0	-0.7	-1.3	-1.5	1.9	1.3	1.0	1.3	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	4.4	1.2	1.3	1.3	-0.9	-1.5	-1.2	-2.1	1.6	1.3	0.8	1.3	1.3
Osteoarthritis (self-reported)	1.5	1.9	3.1	-1.8	-1.4	-1.7	-1.4	0.5	1.3	1.1	-0.8	-1.5	-1.5	-1.5	-1.7
Medication: Lansoprazole	1.4	1.6	5.7	1.5	0.9	1.1	0.3	1.6	-2.4	-0.6	1.5	1.0	1.1	1.1	1.1
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	5.8	-1.1	-1.4	-1.4	-0.3	-0.8	0.9	1.0	-0.8	-1.5	-2.4	-1.6	-1.4
Medication: Amlodipine	1.4	2.0	2.7	1.7	1.5	1.5	1.0	0.1	-1.1	-1.6	1.5	1.4	1.6	1.5	1.5
Angina	1.3	1.7	3.5	-1.5	-1.4	-1.5	0.0	0.5	-0.3	1.5	-1.9	-1.5	-1.5	-1.5	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	1.3	2.8	4.6	1.4	1.7	2.0	-1.1	-0.3	-1.0	-2.1	2.0	1.9	1.9	1.9	1.9
Supplements: Glucosamine	1.3	1.7	4.2	1.3	1.4	1.4	0.8	-1.0	-0.8	-1.4	2.1	1.4	0.9	1.3	1.2
Hair/balding pattern: Pattern 2	1.3	1.6	3.4	-1.1	-1.4	-1.5	0.1	0.7	-0.3	1.4	-1.1	-1.5	-1.9	-1.5	-1.5
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.6	2.9	1.4	1.2	1.6	0.9	-1.0	-0.3	-1.6	1.7	1.4	0.6	1.3	1.5
Illnesses of father: None of the above (group 1)	1.3	1.6	7.1	0.4	1.0	0.9	1.1	-2.7	-0.6	-1.8	0.6	1.0	1.4	1.0	0.9
Hearing aid user	1.3	1.4	3.3	1.3	1.4	1.3	0.2	0.2	-1.8	-0.9	0.7	1.3	1.2	1.3	1.4
Irritability	1.3	2.1	5.3	-1.2	-1.6	-1.3	-0.1	1.9	0.3	2.3	-0.7	-1.5	-1.9	-1.5	-1.4
HDL Cholesterol	1.2	2.0	12.1	1.0	1.4	1.1	3.5	-0.9	-0.2	-1.1	0.6	1.2	1.0	1.1	1.1
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.5	-1.2	-1.3	-1.1	1.9	0.7	0.7	1.6	-0.0	-1.1	-1.7	-1.2	-1.1
Vitamin and mineral supplements	1.2	1.7	3.6	-1.9	-1.5	-1.4	-1.1	-1.0	1.5	0.4	-1.1	-1.4	-0.9	-1.3	-1.4
Severe depression (siblings)	1.2	1.3	2.5	0.8	1.3	1.2	0.0	-1.5	0.6	-1.1	1.1	1.3	1.6	1.3	1.1
Waist circumference	1.2	4.2	8.5	-2.0	-2.1	-2.2	-0.3	1.1	0.4	2.8	-2.1	-2.2	-2.9	-2.3	-2.2
Allergy	1.2	2.8	3.7	1.9	1.8	1.9	1.1	1.2	-1.9	-0.5	1.6	1.9	1.9	1.8	1.8
Impedance of arm (left)	1.2	5.4	9.5	-2.6	-2.7	-2.7	0.1	-0.2	2.5	2.0	-1.7	-2.7	-3.1	-2.8	-2.6
Pulse wave peak to peak time	1.2	1.4	2.3	-1.4	-1.1	-1.2	-1.1	-1.4	1.3	0.4	-1.0	-1.1	-1.5	-1.2	-1.2
Medication: Allopurinol	1.2	1.6	3.5	1.0	1.5	1.5	0.4	0.4	-1.4	-0.6	1.9	1.5	1.1	1.5	1.4
Qualifications: nursing, teaching	1.2	1.8	2.9	1.4	1.7	1.6	0.7	0.5	-1.3	-0.8	0.9	1.6	1.5	1.6	1.6
Fractured/broken bones in last 5 years	1.2	1.5	3.4	-1.5	-1.1	-1.3	-0.4	-1.4	0.9	0.5	-1.4	-1.2	-1.8	-1.3	-1.2
Neuroticism (2016)	1.1	1.7	4.2	-1.2	-1.1	-1.3	-0.6	1.4	-0.1	2.1	-1.6	-1.2	-1.3	-1.3	-1.2
Current tobacco smoking	1.1	1.9	4.3	1.3	1.5	1.4	-0.3	-1.5	-0.4	-2.1	1.1	1.4	1.6	1.4	1.4
Relative age voice broke	1.1	1.7	4.6	1.3	1.2	1.2	2.1	-0.8	-0.6	-1.5	1.3	1.2	1.5	1.2	1.2
Qualifications: CSEs or equivalent	1.1	1.5	7.5	-1.1	-1.0	-0.7	-1.4	-1.3	2.7	0.3	-0.7	-0.9	-0.9	-0.9	-0.9
High blood pressure (mother)	1.1	1.5	3.0	1.3	1.2	1.5	-0.1	-0.5	-0.3	-1.7	1.6	1.4	1.3	1.4	1.4
Qualifications: A levels/AS levels or equivalent	1.1	2.5	4.0	1.9	1.8	1.8	-0.4	0.6	-0.5	-1.6	1.7	2.0	1.3	1.9	2.0
Whole body fat mass	1.1	4.4	7.6	-2.3	-2.4	-2.3	0.2	0.8	0.6	2.8	-1.8	-2.4	-2.7	-2.5	-2.5
Lupus	1.0	1.5	4.4	1.1	1.1	1.1	1.2	-2.1	-0.9	-1.4	1.2	1.0	1.2	1.1	1.1
Triglycerides	1.0	1.7	4.7	1.3	1.1	1.2	-1.5	-0.3	-2.2	-1.1	1.2	1.2	1.3	1.3	1.3
Sensitivity / hurt feelings	1.0	1.7	7.7	-0.8	-0.6	-0.7	2.8	1.5	-0.1	2.0	-0.4	-0.7	-1.8	-0.8	-0.7
Falls in the last year	1.0	1.4	2.6	1.6	1.4	1.3	1.2	-0.2	-0.2	-0.9	0.3	1.3	1.5	1.3	1.4
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	3.2	-1.0	-0.8	-1.0	-1.8	0.7	0.6	1.0	-1.1	-1.0	-1.3	-1.0	-0.9
Medication: Omeprazole	1.0	1.2	3.8	-1.3	-1.0	-1.1	-0.7	0.1	0.7	1.1	-0.7	-1.1	-1.9	-1.2	-1.1
Average weekly champagne plus white wine intake	1.0	1.3	2.4	1.1	1.1	1.3	-1.2	-0.4	-0.1	-1.6	1.2	1.3	1.1	1.3	1.3
Mother’s age at death	1.0	1.3	3.6	1.0	0.9	0.9	1.2	-1.9	1.0	-1.5	1.4	1.0	0.7	0.9	0.9
Average weekly beer plus cider intake	1.0	1.4	2.3	1.1	1.4	1.3	0.1	-0.7	-1.4	-1.3	1.5	1.4	0.4	1.3	1.4
LDL Cholesterol	0.9	1.5	2.0	1.4	1.3	1.3	-1.4	-0.4	-0.9	-1.0	1.4	1.3	1.2	1.3	1.3
Hearing difficulty/problems: Yes	0.9	1.3	2.2	1.2	1.4	1.5	0.4	-0.5	0.4	-1.2	1.4	1.5	0.8	1.3	1.5
Diabetes (self-reported)	0.9	1.3	4.0	1.2	1.3	1.2	0.8	1.4	-0.7	-0.1	-0.2	1.1	2.0	1.2	1.2
Medication: Ramipril	0.9	1.1	2.7	1.1	1.2	1.0	0.8	0.8	-1.3	-0.7	0.2	1.1	1.6	1.1	1.0
High blood pressure (siblings)	0.9	1.2	2.3	-1.3	-1.4	-1.2	-0.3	-1.1	-0.0	0.5	-0.9	-1.3	-1.5	-1.3	-1.3
Long-standing illness, disability or infirmity	0.9	1.4	2.3	1.3	1.1	1.1	-1.4	1.5	-1.0	-0.3	1.2	1.2	1.1	1.2	1.2
Osteoporosis (self-reported)	0.9	1.1	2.2	0.4	1.2	0.9	-1.4	-1.4	-0.8	-1.5	1.4	1.0	-0.1	0.9	1.0
Age started oral contraceptive pill	0.9	1.2	1.7	-0.9	-1.3	-1.3	1.3	0.0	0.2	1.0	-1.1	-1.3	-0.9	-1.2	-1.3
Alzheimer’s Disease (in mother)	0.8	0.9	2.7	-0.9	-0.8	-0.9	0.6	-1.6	1.5	0.3	-0.9	-0.8	-0.7	-0.8	-0.8
Major Depression (MDD)	0.8	0.9	3.2	-0.5	-1.0	-0.7	-1.1	1.8	-1.0	0.9	-0.1	-0.9	-1.1	-0.8	-0.7
Type 2 Diabetes (T2D) (2018)	0.8	1.6	4.9	1.1	1.4	1.3	1.0	1.5	-0.7	-0.0	-0.1	1.3	2.2	1.4	1.3
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.0	0.8	1.2	1.2	-0.0	1.0	-0.2	-0.5	0.2	1.0	1.4	1.1	1.0
Trunk fat percentage	0.8	3.3	5.9	-1.8	-2.1	-2.0	0.8	0.6	1.0	2.4	-1.4	-2.1	-2.2	-2.1	-2.1
Townsend deprivation index at recruitment	0.8	1.2	4.0	-0.7	-0.9	-1.0	-1.8	-2.0	0.8	-0.5	-0.8	-1.0	-0.6	-0.9	-0.9
Age when periods started (menarche)	0.8	2.0	3.7	-1.3	-1.6	-1.5	-0.5	1.6	-0.4	1.9	-1.6	-1.6	-0.6	-1.5	-1.6
Worrier / anxious feelings	0.8	1.6	4.2	1.2	1.4	1.3	-0.4	1.2	-1.2	-0.4	2.0	1.5	0.7	1.4	1.3
Number of live births	0.8	1.2	4.0	-1.2	-1.0	-1.0	1.5	-1.0	0.3	0.3	-0.1	-1.0	-2.0	-1.1	-1.0
Eye problems/disorders: None of the above	0.8	0.9	1.5	-1.2	-1.2	-1.2	-0.4	-0.9	0.4	0.2	-1.0	-1.2	-0.9	-1.2	-1.1
Angina (self-reported)	0.8	1.1	2.6	-1.2	-1.0	-1.2	0.0	0.2	-0.6	1.2	-1.6	-1.1	-1.1	-1.1	-1.0
Smoking status: Current	0.8	1.3	3.1	1.2	1.2	1.1	-0.1	-1.2	-0.3	-1.8	0.8	1.1	1.4	1.2	1.1
Commuting to job workplace: Cycle	0.8	1.0	3.1	-1.0	-0.8	-1.0	0.6	0.5	-1.3	1.2	-1.8	-0.9	-0.3	-0.9	-1.0
Schizophrenia vs Biploar Disorder	0.7	0.9	4.0	-0.3	-0.4	-0.2	-1.9	2.0	0.8	1.4	-0.6	-0.3	0.0	-0.3	-0.4
Allergy or Eczema	0.7	1.7	4.5	-1.4	-1.5	-1.5	-0.9	-0.8	1.3	0.3	-0.2	-1.5	-2.1	-1.5	-1.4
Chronotype (morning person)	0.7	1.6	4.4	-0.9	-1.0	-1.0	-2.1	1.8	-0.2	1.9	-1.5	-1.1	-0.4	-1.0	-1.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.8	4.3	-0.4	-0.5	-0.6	-2.1	1.6	-0.9	0.9	-0.4	-0.4	-0.3	-0.4	-0.5
Past tobacco smoking	0.7	1.3	7.9	-0.0	0.5	0.4	-1.2	-2.8	1.5	-1.8	0.2	0.4	0.0	0.4	0.4
Alcohol usually taken with meals	0.7	1.1	3.9	-0.6	-1.1	-1.0	-0.5	1.4	-0.5	2.0	-0.7	-1.0	-0.8	-1.0	-1.0
Lung cancer (father)	0.7	0.8	3.6	-0.3	-0.6	-0.6	-1.9	1.2	1.2	0.6	-0.1	-0.7	-0.8	-0.6	-0.6
Shortness of breath walking on level ground	0.7	0.9	2.8	-0.4	-0.9	-0.9	-1.6	0.7	-0.8	0.8	-1.7	-0.9	0.2	-0.8	-0.7
Chest pain or discomfort	0.7	1.1	2.2	0.9	1.0	1.0	-1.0	-1.1	-1.5	-0.8	1.0	0.9	1.2	1.0	0.9
Family relationship satisfaction	0.7	0.9	3.6	-0.3	-1.0	-0.9	-0.9	-0.5	-1.9	-0.1	-0.1	-0.9	-1.2	-0.9	-0.9
Commuting to job workplace: Car/motor vehicle	0.7	0.8	6.3	-0.7	-0.2	-0.1	-0.7	-2.5	0.7	-1.0	-0.4	-0.1	0.3	-0.1	-0.2
Handedness (chirality/laterality): Left-handed	0.7	0.9	1.8	-0.9	-1.1	-1.0	0.3	1.0	-1.3	0.7	-0.7	-1.0	-0.9	-1.0	-0.9
Diabetes diagnosed by doctor	0.7	1.2	4.4	1.1	1.3	1.1	0.2	1.0	-0.8	-0.2	0.0	1.1	2.1	1.2	1.1
Guilty feelings	0.7	1.0	6.3	0.0	-0.2	-0.1	0.6	2.5	-1.5	1.5	0.7	-0.1	-0.6	-0.1	-0.1
Impedance of whole body	0.7	3.6	5.2	-2.2	-2.2	-2.2	0.4	-0.4	2.3	1.7	-1.6	-2.2	-1.9	-2.2	-2.1
Crohns Disease (2017)	0.6	1.2	1.8	-0.9	-1.3	-1.2	-0.4	1.0	-0.9	1.2	-1.3	-1.3	-0.7	-1.2	-1.3
Schizophrenia (2014)	0.6	1.4	3.6	1.6	1.1	1.3	-0.8	0.5	-1.9	-0.5	1.6	1.1	0.3	1.1	1.3
Average weekly spirits intake	0.6	0.8	2.2	1.1	0.6	1.0	1.0	0.5	-0.2	-0.5	0.8	0.9	1.5	0.9	0.9
Relative age of first facial hair	0.6	1.2	3.7	0.8	1.1	1.0	1.3	-1.2	-0.4	-1.9	0.7	1.0	1.2	1.0	1.0
Impedance of leg (right)	0.6	3.1	4.5	-2.0	-2.1	-2.1	0.5	0.2	1.9	1.8	-1.9	-2.1	-1.1	-2.0	-2.1
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.6	-1.1	-1.0	-1.2	-1.5	-0.2	1.9	0.4	-0.8	-1.2	-1.2	-1.1	-1.1
Number of incorrect matches in round	0.6	0.9	1.4	-1.0	-1.0	-0.9	0.8	-1.2	0.9	1.2	-0.8	-0.9	-0.7	-1.0	-1.0
Medication: Cholesterol lowering	0.6	0.9	2.2	1.1	1.1	1.0	1.2	0.6	-0.5	-0.3	0.2	1.1	1.5	1.1	1.0
Pulse wave reflection index	0.6	0.8	1.7	0.7	0.7	1.1	-0.6	-0.9	-0.6	-0.7	1.3	0.9	0.9	0.9	0.9
Number of children fathered	0.6	0.7	1.6	-0.8	-0.8	-0.7	-1.1	-1.3	0.9	0.3	0.0	-0.9	-0.7	-0.7	-0.8
Age at first live birth	0.6	1.1	2.0	1.2	1.1	1.2	0.0	-0.9	-0.3	-1.4	0.8	1.1	1.4	1.2	1.0
Leg fat mass (right)	0.6	2.3	4.1	-1.7	-1.7	-1.7	0.2	0.4	0.4	2.0	-1.6	-1.8	-1.6	-1.8	-1.8
Risk taking	0.6	0.8	2.0	1.1	0.8	1.1	0.9	0.2	-0.9	-0.7	1.4	1.0	0.3	0.9	0.8
Bipolar Disorder or Schizophrenia	0.5	1.2	5.7	1.2	1.0	1.1	0.5	-0.4	-2.4	-0.6	1.1	0.8	-0.3	0.8	1.1
Schizophrenia (2018)	0.5	1.0	3.5	1.2	1.0	1.0	-0.8	0.5	-1.9	-0.3	1.1	0.9	0.1	0.9	1.1
Systolic Blood Pressure	0.5	2.6	4.0	-1.7	-2.0	-1.9	-1.9	0.0	1.1	1.5	-1.8	-1.9	-0.3	-1.7	-1.9
Hair Pigment	0.5	15.4	24.2	-4.5	-4.8	-4.7	0.6	0.5	0.3	4.5	-3.6	-4.8	-3.9	-4.7	-4.9
Systolic blood pressure, automated reading	0.5	1.4	2.6	-1.1	-1.5	-1.4	-0.8	0.4	1.6	1.4	-0.8	-1.3	-0.4	-1.2	-1.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.3	-0.9	-0.8	-0.6	-0.8	0.4	0.8	0.5	-0.8	-0.7	-1.1	-0.8	-0.7
Chronic bronchitis/emphysema (father)	0.5	0.5	2.1	0.8	0.8	0.4	0.3	0.1	-1.5	-0.1	1.1	0.6	0.4	0.7	0.6
Pain all over the body in last month	0.5	0.5	1.3	-0.3	-0.6	-0.7	-1.1	1.0	-0.7	0.3	-1.0	-0.7	-0.4	-0.7	-0.7
Fluid intelligence score	0.5	1.1	4.1	1.0	1.0	0.9	-1.3	2.0	-0.9	-0.1	0.8	1.0	0.8	1.0	0.9
Pulse wave Arterial Stiffness index	0.5	0.5	3.3	0.6	0.3	0.4	0.7	1.8	-1.0	0.4	0.3	0.3	0.5	0.4	0.4
Length of working week for main job	0.5	0.6	5.4	0.1	0.0	0.2	-2.3	-0.5	0.7	-0.5	0.5	0.2	0.0	0.2	0.2
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.2	0.2	0.9	0.9	0.3	-0.9	0.8	-1.5	0.9	0.9	0.1	0.9	0.9
Gout (self-reported)	0.5	0.7	2.4	0.2	1.0	0.9	1.0	0.4	-1.6	-0.3	0.8	0.9	0.7	0.9	0.8
Birth weight	0.5	1.0	4.3	-0.9	-0.9	-0.9	-0.4	0.3	0.3	1.4	-0.9	-0.9	-2.1	-1.1	-0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	1.0	0.8	0.9	1.0	0.7	1.0	-1.0	-0.4	0.4	0.8	0.8	0.9	1.0
Illnesses of father: Heart disease	0.5	0.7	1.8	-0.5	-0.9	-0.8	-1.0	0.7	0.5	0.7	-0.9	-0.8	-1.3	-0.9	-0.7
Friendships satisfaction	0.5	0.6	1.7	-0.4	-0.8	-0.9	-0.2	0.5	-1.3	0.6	-0.2	-0.7	-1.2	-0.8	-0.9
Financial situation satisfaction	0.5	0.6	2.0	0.6	0.5	0.5	-1.4	0.1	-0.9	-1.0	1.1	0.6	0.4	0.6	0.5
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.9	-0.4	-0.1	-0.5	-0.0	1.4	-1.1	1.3	-1.1	-0.3	-0.0	-0.3	-0.3
Number of operations (self-reported)	0.5	0.7	1.6	-0.7	-0.5	-0.6	-1.1	1.2	-1.0	1.3	-0.6	-0.6	-0.5	-0.6	-0.7
Ever depressed for a whole week	0.5	0.6	2.3	-0.8	-0.7	-0.6	-1.0	0.5	-1.5	0.4	-0.7	-0.6	-0.2	-0.6	-0.6
Alcohol drinker status: Previous	0.5	0.5	1.5	0.7	0.7	0.8	0.3	-0.2	-1.2	-0.4	0.4	0.6	1.1	0.8	0.8
Bipolar Disorder (2018)	0.4	0.7	2.2	0.5	0.4	0.5	1.5	-1.2	-1.5	-0.7	0.5	0.2	-0.6	0.3	0.4
Neuroticism (Nagel 2018)	0.4	0.9	3.2	-0.6	-0.6	-0.5	0.9	1.8	-0.7	1.8	0.1	-0.6	-1.2	-0.7	-0.7
Irritable Bowel Disease (IBD)	0.4	1.0	5.7	-0.5	-0.8	-0.7	-0.4	2.4	-0.6	1.3	-0.7	-0.7	-0.4	-0.7	-0.9
Breast Cancer	0.4	1.1	3.6	0.9	0.9	1.1	-1.0	-0.7	-1.9	-0.4	0.8	0.9	1.0	1.0	1.0
Body Mass Index (BMI) (2010)	0.4	0.6	2.8	-0.5	-0.5	-0.5	-1.1	1.7	0.5	1.1	-0.6	-0.5	-0.1	-0.4	-0.5
Rheumatoid Arthritis	0.4	0.5	1.1	-0.5	-0.6	-0.7	0.9	-0.4	0.1	0.8	-1.0	-0.8	-0.7	-0.8	-0.7
Ulcerative Colitis	0.4	0.6	5.5	0.5	0.3	0.5	0.0	2.3	-0.5	0.8	0.1	0.5	0.5	0.4	0.3
Blood Eosinophil Count	0.4	2.9	13.5	-0.9	-1.2	-1.1	2.8	-1.1	3.7	0.8	-0.9	-1.2	-1.6	-1.2	-1.3
Medication: Co-codamol	0.4	0.4	1.7	0.3	0.5	0.6	-0.3	-1.3	-0.6	-0.9	0.7	0.5	-0.2	0.4	0.6
Fed-up feelings	0.4	0.6	1.2	-0.8	-1.1	-0.9	0.8	-0.2	-0.2	0.7	-0.7	-0.8	-1.1	-0.9	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.3	-0.0	0.2	0.2	-0.0	-1.5	-1.5	-1.1	0.3	0.2	-0.2	0.2	0.2
Serious illness, injury or assault to yourself	0.4	0.5	2.0	0.6	0.5	0.6	0.4	1.4	-1.4	0.5	0.1	0.5	0.5	0.5	0.5
Impedance of leg (left)	0.4	1.8	2.4	-1.6	-1.4	-1.5	1.2	-0.1	1.5	1.5	-1.5	-1.5	-0.6	-1.4	-1.5
Neuroticism score	0.4	0.8	2.5	-0.8	-0.8	-0.7	0.2	1.5	-0.7	1.6	0.1	-0.7	-1.1	-0.7	-0.7
Alcohol intake versus 10 years previously	0.4	0.6	3.1	0.3	0.0	0.1	-0.1	1.7	-1.8	0.8	0.3	0.0	0.0	-0.0	0.1
Mouth/teeth dental problems: Dentures	0.4	0.6	2.6	-0.6	-0.6	-0.7	0.5	0.2	1.6	0.7	-0.7	-0.7	-1.0	-0.7	-0.6
Arm fat mass (right)	0.4	1.8	3.6	-1.4	-1.4	-1.4	-0.1	0.6	0.3	1.9	-1.1	-1.5	-1.9	-1.5	-1.5
Birth weight of first child	0.4	0.7	2.6	-0.5	-0.6	-0.8	1.3	0.8	-0.6	0.7	-0.3	-0.5	-1.6	-0.8	-0.5
Blood clot in the leg (DVT)	0.4	0.5	2.5	-0.0	-0.5	-0.1	-1.6	-0.7	-1.3	-0.6	-0.2	-0.2	0.8	-0.1	-0.3
Worry too long after embarrassment	0.4	0.6	5.1	-0.0	-0.0	0.1	0.3	2.3	0.7	1.1	0.3	0.1	-0.5	-0.1	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.4	-0.4	0.1	-0.4	-0.7	1.2	-1.0	0.8	-0.9	-0.1	-0.9	-0.2	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.5	0.2	0.3	0.4	0.2	-1.4	1.6	-0.7	0.3	0.4	-0.1	0.3	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	3.3	-0.4	-0.2	-0.0	1.8	-1.1	0.6	0.2	-0.5	-0.1	0.5	-0.1	-0.2
Suffer from ‘nerves’	0.4	0.7	3.1	-0.5	-0.7	-0.7	-1.1	1.8	-0.2	0.8	-0.9	-0.7	-0.3	-0.6	-0.7
Loneliness, isolation	0.4	0.5	1.2	-0.8	-0.9	-0.7	0.1	-0.6	-0.3	0.7	-0.7	-0.8	-1.1	-0.8	-0.8
Ever had bowel cancer screening	0.4	0.5	1.4	-0.8	-0.7	-0.8	-0.2	0.3	-0.1	0.9	-1.2	-0.7	-0.8	-0.8	-0.6
Medication: Gliclazide	0.4	0.4	1.2	1.1	0.6	0.5	0.5	0.7	-0.3	0.3	-0.1	0.6	1.1	0.6	0.5
Arm fat mass (left)	0.4	1.7	3.4	-1.4	-1.4	-1.4	-0.1	0.7	0.4	1.9	-1.0	-1.4	-1.8	-1.4	-1.5
Supplements: Calcium	0.4	0.4	0.9	-0.9	-0.6	-0.7	0.0	-0.2	1.0	0.6	-0.3	-0.7	-0.6	-0.7	-0.8
Basal cell carcinoma (self-reported)	0.4	0.5	3.6	-0.4	-0.7	-0.3	0.3	-0.7	1.9	0.3	0.1	-0.5	0.0	-0.4	-0.5
Leg fat mass (left)	0.4	1.6	3.5	-1.4	-1.3	-1.3	0.3	0.3	0.1	1.9	-1.3	-1.4	-1.4	-1.4	-1.5
Intelligence (Savage-Jansen 2018)	0.3	1.0	4.2	1.0	1.0	0.7	-0.2	2.1	-1.2	0.9	0.5	0.8	0.6	0.9	0.9
Ulcerative Colitis (UC)	0.3	0.6	3.8	0.8	0.5	0.5	-0.4	2.0	-0.6	0.0	0.9	0.6	0.6	0.6	0.4
Reaction Time	0.3	0.5	1.9	0.5	0.8	0.8	0.4	1.4	-0.5	0.3	0.5	0.7	0.3	0.7	0.9
Verbal and Numeric Reasoning (VNR)	0.3	0.7	3.5	0.7	0.8	0.7	-0.7	1.9	-0.9	0.4	0.6	0.8	0.3	0.8	0.7
Ovarian Cancer	0.3	0.4	3.2	0.6	0.0	-0.0	1.8	0.8	0.1	0.2	0.7	0.2	-0.7	0.0	0.2
Bipolar Disorder (2011)	0.3	0.3	0.8	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.7	0.9	0.6	0.9	0.9
Lung FVC	0.3	1.4	2.3	1.3	1.5	1.2	0.2	0.1	-0.8	-1.5	1.3	1.4	1.0	1.3	1.2
Hand grip strength (left)	0.3	0.7	2.1	1.0	0.8	0.9	0.6	-0.1	-1.1	-0.9	-0.0	0.6	1.4	0.8	0.7
Medication for hormone replacement therapy	0.3	0.4	2.2	-0.4	-0.7	-0.5	-0.2	-0.8	-1.5	0.2	-0.1	-0.5	-0.2	-0.5	-0.5
Diabetes (father)	0.3	0.4	0.6	0.5	0.7	0.6	-0.3	0.4	-0.8	-0.3	0.6	0.7	0.7	0.7	0.6
Taking other prescription medications	0.3	0.4	1.7	0.2	0.3	0.5	-0.9	-0.2	-1.3	-0.3	1.1	0.4	0.1	0.4	0.4
Multivitamins +/- minerals	0.3	0.4	1.0	1.0	0.6	0.5	0.7	0.6	-0.8	-0.2	0.7	0.5	-0.0	0.5	0.5
Had menopause	0.3	0.4	2.9	0.0	-0.1	0.0	1.7	-0.2	0.6	0.4	0.8	0.0	-0.3	-0.1	-0.1
Financial difficulties in last 2 years	0.3	0.4	0.6	0.8	0.5	0.7	-0.6	-0.3	-0.6	-0.8	0.7	0.7	0.6	0.6	0.6
Medication: Simvastatin	0.3	0.4	0.7	0.5	0.9	0.7	0.8	-0.4	-0.5	-0.2	0.2	0.7	0.7	0.7	0.7
Happiness	0.3	0.4	1.3	0.0	-0.3	-0.4	-1.0	-0.7	-1.1	-1.0	-0.2	-0.3	-0.9	-0.4	-0.3
Illnesses of mother	0.3	0.4	2.8	-0.1	-0.1	-0.1	0.8	1.7	-0.2	0.9	-0.2	-0.1	-0.0	-0.1	-0.2
Exposure to tobacco smoke at home	0.3	0.4	2.7	0.5	0.4	0.3	-0.1	-1.6	-0.0	-0.8	0.3	0.3	0.3	0.3	0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.4	-0.5	-0.2	-0.2	-0.7	0.9	-1.2	0.7	-0.5	-0.2	0.5	-0.1	-0.3
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.7	0.3	-0.0	0.1	-1.6	-0.9	0.5	-1.0	1.0	0.0	-0.6	0.0	0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.2	-0.6	-0.8	-0.8	0.7	0.2	-0.3	1.1	-0.2	-0.8	-0.7	-0.8	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.7	0.7	0.5	0.6	0.7	-0.2	-0.7	-0.7	0.8	0.5	-0.3	0.5	0.6
Number of full brothers	0.3	0.4	1.5	-0.7	-0.5	-0.6	-0.2	0.0	0.6	0.9	-1.2	-0.6	0.0	-0.5	-0.5
Health satisfaction	0.3	0.4	3.6	0.2	0.3	0.1	-1.9	0.5	-0.5	-0.9	-0.1	0.1	-0.1	0.1	0.1
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.6	0.5	0.8	0.5	1.3	-0.2	-0.3	-0.3	-0.1	0.7	0.6	0.6	0.6
Medication: Seretide 50 evohaler	0.3	0.3	1.4	0.2	0.5	0.6	0.4	-1.2	0.4	-0.5	0.5	0.4	-0.1	0.4	0.5
Mean time to correctly identify matches	0.3	0.6	1.6	0.5	0.8	0.8	0.9	1.3	0.2	0.3	0.8	0.9	0.1	0.7	0.9
Alcohol intake frequency.	0.3	0.6	2.8	0.3	0.6	0.2	-1.7	0.7	-1.6	-0.0	-0.6	0.2	0.2	0.3	0.4
Had major operations	0.3	0.4	4.3	0.0	0.2	0.1	-0.4	0.0	-2.1	0.3	-0.2	0.2	0.4	0.1	0.0
Age at last live birth	0.3	0.5	1.1	0.6	0.6	0.8	0.6	-0.8	-0.9	-1.0	0.5	0.6	0.3	0.6	0.6
Mood swings	0.3	0.6	1.0	-0.9	-1.0	-0.6	0.5	0.2	-0.2	1.0	-0.4	-0.9	-0.8	-0.9	-0.9
Commuting to job workplace: Walk	0.3	0.4	1.8	-0.5	-0.6	-0.5	1.4	-0.2	0.6	-0.0	-0.4	-0.5	-0.3	-0.5	-0.5
Eye problems/disorders: Cataract	0.3	0.4	2.1	-0.5	-0.2	-0.4	0.2	0.4	1.5	0.9	-0.7	-0.4	0.0	-0.3	-0.5
Medication for cholesterol	0.3	0.4	2.6	0.2	0.4	0.2	1.1	1.6	0.4	0.6	-0.3	0.3	0.3	0.2	0.1
Medication: Aspirin	0.3	0.3	1.2	0.5	0.4	0.5	1.1	0.3	0.1	-0.0	-0.6	0.5	1.0	0.4	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	1.3	0.8	0.9	0.7	1.0	-1.1	-0.1	-1.2	0.4	0.9	0.7	0.8	0.8
Number of self-reported non-cancer illnesses	0.3	0.5	4.0	-0.1	-0.2	-0.3	-0.9	0.9	-2.0	0.4	0.1	-0.2	-0.0	-0.2	-0.2
Miserableness	0.3	0.5	1.1	-1.1	-1.0	-0.8	-0.6	-0.2	-0.3	0.5	-0.5	-0.9	-0.4	-0.8	-1.0
Medication: Bendroflumethiazide	0.3	0.5	1.4	-0.5	-0.5	-0.5	0.7	1.2	0.7	1.1	-0.8	-0.5	-0.4	-0.5	-0.5
Medication: Atorvastatin	0.3	0.4	2.1	0.6	0.3	0.2	-1.4	0.6	0.1	-0.5	0.5	0.4	0.6	0.4	0.4
Illnesses of father: High blood pressure	0.3	0.4	1.8	-0.1	-0.3	0.1	-1.1	1.2	1.3	0.5	0.1	-0.2	0.0	-0.1	-0.1
Unable to work because of sickness or disability	0.3	0.4	2.8	-0.1	0.3	0.4	-0.4	-1.7	-0.4	-0.8	-0.0	0.3	0.6	0.3	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.5	-0.2	-0.7	-0.3	-1.2	-0.8	-1.1	-0.4	-0.4	-0.4	0.5	-0.4	-0.5
Depressed Affect (Nagel 2018)	0.2	0.5	1.7	-0.7	-0.8	-0.6	0.2	0.2	-1.3	1.1	-0.0	-0.6	-0.7	-0.6	-0.7
Depression (Nagel 2018)	0.2	0.3	1.8	0.2	0.3	0.2	0.1	-0.9	-1.3	-0.6	-0.2	0.3	0.1	0.3	0.3
Crohns Disease (2012)	0.2	0.4	2.7	0.5	-0.1	0.2	-0.3	0.9	-1.6	0.1	-0.3	-0.0	0.9	0.1	-0.0
Fasting Glucose	0.2	0.2	1.0	0.4	0.5	0.3	-0.5	0.5	-1.0	0.0	0.2	0.4	0.1	0.4	0.4
Primary Biliary Cirrhosis	0.2	0.3	2.2	0.3	0.5	0.3	0.6	0.2	-1.5	-0.4	0.0	0.5	0.4	0.4	0.5
Waist Hip Ratio (WHR)	0.2	1.1	2.9	-0.9	-1.1	-1.2	-0.6	0.3	0.2	0.8	-1.2	-1.1	-1.7	-1.2	-1.1
Cardiovascular Disease	0.2	0.8	5.3	-0.5	-0.5	-0.7	-2.3	-0.0	-0.2	0.9	-1.0	-0.6	0.2	-0.5	-0.8
Respiratory disease	0.2	0.5	2.3	-0.3	-0.2	-0.2	-0.2	-1.5	0.3	-0.4	0.6	-0.2	-1.5	-0.3	-0.1
Neuroticism	0.2	0.4	1.7	-0.3	-0.3	-0.3	0.6	1.2	-0.9	1.3	0.1	-0.3	-0.6	-0.3	-0.3
Tanning	0.2	2.2	6.1	-1.4	-1.4	-1.2	-0.7	-2.5	2.5	0.4	-1.1	-1.4	-1.4	-1.4	-1.3
Hand grip strength (right)	0.2	0.4	1.7	0.6	0.6	0.6	-0.1	0.4	-1.0	-0.4	-0.3	0.5	1.3	0.6	0.4
Stomach or abdominal pain in last month	0.2	0.3	1.5	0.3	-0.3	0.1	-0.8	1.2	0.6	0.3	0.5	-0.1	0.6	-0.0	-0.1
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.7	-0.7	-0.1	-0.5	-0.5	0.4	0.6	0.6	-0.8	-0.3	0.6	-0.2	-0.4
Medication: Levothyroxine sodium	0.2	0.3	2.0	-0.4	-0.4	-0.5	1.4	-0.3	-0.5	0.5	0.1	-0.4	-0.5	-0.4	-0.5
Time employed in main current job	0.2	0.2	1.0	-0.2	-0.3	-0.1	-1.0	-0.8	0.1	-0.5	0.3	-0.2	0.0	-0.2	-0.3
Father’s age at death	0.2	0.2	0.8	0.4	0.3	0.4	-0.4	0.5	-0.9	-0.6	0.4	0.4	0.7	0.4	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.5	-0.4	-0.4	-0.4	-1.1	0.0	-0.4	0.1	-1.2	-0.4	-0.0	-0.4	-0.4
Noisy workplace	0.2	0.3	3.0	-0.1	-0.3	-0.2	1.7	-0.5	-0.2	0.0	-0.0	-0.2	-0.2	-0.2	-0.1
Asthma	0.2	0.3	3.0	-0.4	0.0	-0.1	0.1	-1.7	0.0	-0.6	0.0	-0.2	-0.5	-0.1	-0.1
Depression (self-reported)	0.2	0.2	0.5	0.2	0.7	0.5	0.1	0.4	-0.3	-0.5	-0.1	0.6	0.4	0.6	0.5
Tense / ‘highly strung’	0.2	0.4	2.0	-0.3	-0.7	-0.5	1.4	0.3	-0.3	0.7	-0.2	-0.5	-0.6	-0.5	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.0	-0.9	-0.4	-0.6	-1.0	0.1	-0.0	0.4	-0.6	-0.4	-0.7	-0.5	-0.6
Body fat percentage	0.2	0.8	1.9	-0.8	-0.9	-0.9	1.1	0.4	0.3	1.4	-0.5	-0.9	-0.9	-0.9	-1.0
Neck or shoulder pain in last month	0.2	0.2	0.9	-0.3	-0.4	-0.3	-0.0	-0.7	1.0	-0.0	-0.4	-0.4	-0.7	-0.4	-0.4
Medication: Blood pressure	0.2	0.4	2.4	-0.3	0.1	0.0	1.6	0.6	-0.3	0.8	-0.8	0.0	0.7	0.1	-0.0
Number of full sisters	0.2	0.2	1.5	-0.0	-0.2	-0.1	0.9	0.2	-1.2	-0.2	-0.5	-0.3	-0.1	-0.3	-0.1
Overall health rating	0.2	0.4	2.2	-0.0	-0.1	-0.2	-0.6	1.5	-1.4	0.4	0.4	-0.0	-0.6	-0.1	-0.1
Medication: Aspirin	0.2	0.3	2.1	0.3	0.0	0.2	1.4	0.2	0.4	0.2	-0.7	0.2	0.8	0.1	0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.7	0.5	0.3	0.4	-0.7	0.2	0.1	-0.5	0.8	0.4	0.5	0.4	0.5
Illnesses of siblings: Diabetes	0.2	0.3	1.5	-0.0	-0.1	-0.1	1.2	-0.4	1.1	-0.1	-0.3	0.0	0.6	0.0	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.5	-0.4	-0.4	-0.3	0.5	0.4	0.2	0.3	-0.3	-0.3	-0.7	-0.4	-0.3
Asthma (self-reported)	0.2	0.5	3.4	-0.7	-0.3	-0.4	0.2	-1.8	0.5	-0.5	-0.2	-0.5	-0.8	-0.4	-0.4
Wears glasses or contact lenses	0.2	0.2	1.6	0.3	0.4	0.3	1.3	-0.5	0.5	-0.2	-0.1	0.3	-0.4	0.3	0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.2	-0.8	-0.4	-0.2	0.1	-0.0	1.1	0.6	-0.2	-0.3	-0.2	-0.3	-0.4
High cholesterol (Self-reported)	0.2	0.3	1.0	0.3	0.6	0.4	-0.4	-1.0	-0.7	-0.4	0.3	0.5	0.6	0.5	0.5
Medication: Lisinopril	0.2	0.2	0.6	0.2	0.1	0.4	0.4	-0.7	0.1	-0.8	0.7	0.2	-0.5	0.1	0.3
Worry (Nagel 2018)	0.1	0.2	0.8	0.3	0.3	0.2	0.7	0.3	-0.9	0.1	0.6	0.3	-0.2	0.3	0.3
Alzheimer’s Disease (in father)	0.1	0.1	0.8	-0.3	0.2	0.1	-0.9	0.2	0.7	-0.1	-0.1	0.1	0.2	0.2	0.0
Alzheimer’s Disease (including proxy)	0.1	0.2	1.4	-0.4	-0.1	-0.2	-0.2	-0.6	1.2	-0.0	-0.5	-0.3	-0.3	-0.1	-0.2
Age at First Birth	0.1	0.2	0.6	0.5	0.3	0.2	-0.3	-0.4	-0.6	-0.6	0.8	0.3	-0.1	0.3	0.3
Blood Platelet Count	0.1	0.7	3.5	1.0	0.6	0.6	-0.1	1.9	0.5	0.5	1.2	0.5	0.5	0.6	0.4
Blood Red Count	0.1	0.6	1.9	1.4	0.6	0.6	1.1	-0.1	0.4	-0.6	0.7	0.7	1.0	0.7	0.6
Blood White Count	0.1	0.5	1.8	0.1	0.1	-0.1	0.1	1.1	0.8	1.4	-0.5	-0.2	1.3	-0.0	-0.4
Smoking Status	0.1	0.3	1.5	0.5	0.2	0.0	-0.6	1.2	-1.2	0.4	0.1	0.2	0.5	0.2	0.1
Hypothyroidism (self reported)	0.1	0.2	0.9	-0.4	-0.3	-0.3	0.9	-0.3	-0.5	0.5	0.3	-0.3	-0.1	-0.2	-0.4
Lung FEV1/FVC ratio	0.1	0.3	0.8	-0.3	-0.7	-0.6	0.3	0.3	0.9	0.2	-0.5	-0.6	-0.7	-0.6	-0.4
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.9	0.2	0.3	0.3	0.1	0.3	-0.9	-0.6	-0.0	0.2	-0.2	0.2	0.3
Supplements: Zinc	0.1	0.1	0.6	0.4	-0.3	-0.2	-0.0	0.2	0.0	0.2	0.5	-0.4	-0.8	-0.4	-0.3
Diabetes (mother)	0.1	0.2	0.8	0.2	0.2	0.2	-0.9	-0.7	0.4	-0.4	0.1	0.2	-0.0	0.2	0.2
Maternal smoking around birth	0.1	0.2	0.7	0.5	0.0	0.4	0.4	0.4	-0.9	-0.3	0.6	0.1	-0.0	0.2	0.4
Body mass index (BMI)	0.1	0.6	0.8	0.9	0.9	0.9	0.6	0.1	-0.9	-0.3	0.7	0.8	0.8	0.9	0.8
Nervous feelings	0.1	0.1	0.4	0.3	0.2	-0.0	0.7	0.3	0.5	0.4	0.1	0.2	0.3	0.2	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.3	-0.2	-0.3	-0.2	0.3	0.2	-0.4	0.5	-0.5	-0.3	-0.3	-0.3	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.6	0.2	0.3	0.2	-0.6	0.6	0.1	-0.1	0.8	0.2	-0.3	0.3	0.3
Breastfed as a baby	0.1	0.1	0.6	0.2	0.2	0.1	-0.6	0.8	-0.5	0.5	0.3	0.3	-0.1	0.2	0.2
Peak expiratory flow (PEF)	0.1	0.3	0.8	-0.5	-0.7	-0.4	0.0	0.2	0.5	0.5	-0.4	-0.6	-0.9	-0.6	-0.5
Comparative body size at age 10	0.1	0.2	0.9	0.2	0.4	0.2	-1.0	-0.3	0.7	-0.2	0.4	0.2	0.2	0.3	0.2
Wheeze or whistling in the chest in last year	0.1	0.3	1.3	-0.2	-0.5	-0.4	-0.1	-0.8	1.2	-0.0	-0.4	-0.5	0.0	-0.4	-0.5
Supplements: Vitamin C	0.1	0.1	0.5	0.4	0.2	0.1	-0.6	0.1	0.7	-0.1	-0.7	0.1	-0.4	-0.0	0.1
Knee pain experienced in last month	0.1	0.2	0.9	0.2	0.3	0.5	-0.3	0.1	0.9	-0.4	0.5	0.4	0.2	0.3	0.4
Average weekly red wine intake	0.1	0.2	1.4	0.1	0.1	0.0	0.3	0.3	1.2	0.6	-0.3	0.0	-0.1	0.0	0.0
Back pain experienced in last month	0.1	0.1	0.7	-0.1	0.1	0.3	-0.5	-0.8	-0.4	-0.1	0.3	0.2	-0.2	0.1	0.1
Commuting to job workplace: Public transport	0.1	0.2	0.5	0.3	0.5	0.1	-0.0	0.7	-0.7	0.5	-0.1	0.2	-0.1	0.3	0.4
Medication: Blood pressure	0.1	0.2	0.6	-0.2	-0.5	-0.4	-0.8	-0.7	0.5	-0.3	-0.2	-0.5	-0.4	-0.4	-0.3
Leg fat percentage (left)	0.1	0.2	1.7	0.3	0.2	0.2	1.3	-0.0	-0.1	0.5	0.2	0.2	0.6	0.3	0.1
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.5	-0.1	0.1	0.2	0.5	0.7	-0.2	-0.1	0.6	0.2	-0.2	0.1	0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.4	0.5	0.4	0.6	0.4	-0.4	-0.2	-0.7	0.5	0.5	0.5	0.5	0.5
Cholesterol lowering medication	0.1	0.2	1.6	-0.2	0.1	-0.0	-0.2	-1.3	-0.3	-0.3	0.3	0.0	-0.3	0.0	0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.6	-0.2	0.1	0.1	0.2	-0.0	-0.5	0.1	0.6	0.1	-0.8	-0.0	0.1
Pain experienced in last month	0.1	0.2	0.6	-0.6	-0.3	-0.5	0.4	-0.0	-0.4	0.7	-0.8	-0.4	-0.1	-0.3	-0.4
Pack years of smoking	0.1	0.1	0.4	-0.4	-0.4	-0.4	-0.2	-0.3	0.2	-0.1	-0.1	-0.4	-0.6	-0.4	-0.3
BMI	0.0	0.2	0.9	0.3	0.4	0.3	-0.2	0.6	-0.7	0.2	-0.5	0.3	0.9	0.4	0.2
Pack years adult smoking proportion	0.0	0.0	0.2	-0.1	-0.1	-0.1	-0.5	-0.2	-0.1	-0.3	-0.0	-0.1	-0.3	-0.1	-0.1
Average weekly fortified wine intake	0.0	0.0	0.1	0.1	0.2	0.0	0.3	0.3	0.2	0.1	0.1	0.1	0.1	0.2	0.1
High blood pressure	0.0	0.1	0.2	0.2	0.3	0.1	-0.1	-0.5	0.3	-0.2	-0.0	0.2	0.4	0.2	0.1
Arm fat percentage (right)	0.0	0.1	0.4	-0.1	-0.1	-0.0	0.6	0.2	-0.1	0.4	0.3	-0.1	-0.5	-0.1	-0.2
Leg fat percentage (right)	0.0	0.1	1.1	0.1	-0.1	-0.1	1.0	0.2	0.1	0.6	-0.0	-0.1	0.5	-0.0	-0.2
Hypertension (Self-reported)	0.0	0.1	0.4	0.0	0.1	-0.1	-0.0	-0.5	0.6	-0.2	-0.2	-0.0	0.2	0.0	-0.1
Arm fat percentage (left)	0.0	0.1	0.7	0.3	0.2	0.2	0.8	0.1	-0.1	0.2	0.5	0.2	-0.2	0.2	0.1

Hub : Genes

ATP5SL

Models

Trait associations