TWAS hub - B3GNT8

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.1380	0.0510	8.2e-04	0.087	NA	0.056	NA	0.083	1.6e-05	NA	5.0e-04	NA	2.6e-05
2	GTEx	Brain Cerebellar Hemisphere	0.3780	0.0950	5.3e-05	0.299	NA	0.173	NA	0.234	2.1e-08	NA	3.4e-05	NA	1.1e-06
3	GTEx	Brain Cerebellum	0.2750	0.0740	1.4e-04	0.231	NA	0.198	NA	0.207	1.9e-07	NA	1.7e-06	NA	9.2e-07
4	GTEx	Cells Transformed fibroblasts	0.0960	0.0380	2.2e-03	0.023	NA	0.030	NA	0.031	6.8e-03	NA	2.3e-03	NA	2.0e-03
5	GTEx	Colon Transverse	0.2080	0.0640	6.0e-05	0.173	NA	0.173	NA	0.179	1.3e-08	NA	1.3e-08	NA	6.7e-09
6	GTEx	Esophagus Muscularis	0.1390	0.0450	2.1e-04	0.097	NA	0.146	NA	0.158	1.8e-06	NA	3.4e-09	NA	7.5e-10
7	GTEx	Heart Left Ventricle	0.2736	0.0787	2.4e-05	0.041	NA	0.041	NA	0.060	3.1e-03	NA	3.1e-03	NA	3.9e-04
8	GTEx	Nerve Tibial	0.2196	0.0487	5.4e-09	0.167	NA	0.196	NA	0.180	6.9e-12	NA	6.6e-14	NA	8.5e-13
9	GTEx	Skin Sun Exposed Lower leg	0.1080	0.0380	4.2e-04	0.038	NA	0.031	NA	0.046	4.0e-04	NA	1.3e-03	NA	1.1e-04
10	GTEx	Stomach	0.2160	0.0590	2.6e-05	0.137	NA	0.111	NA	0.125	4.5e-07	NA	5.7e-06	NA	1.4e-06
11	GTEx	Thyroid	0.0920	0.0340	2.3e-03	0.037	NA	0.033	NA	0.032	8.0e-04	NA	1.4e-03	NA	1.7e-03
12	TCGA	Bladder Urothelial Carcinoma	0.0320	0.0220	4.6e-04	0.043	0.038	0.029	NA	0.030	1.4e-04	3.2e-04	1.5e-03	NA	1.4e-03
13	TCGA	Breast Invasive Carcinoma	0.0402	0.0224	5.9e-13	0.066	0.067	0.067	NA	0.066	2.4e-13	1.2e-13	1.3e-13	NA	2.1e-13
14	TCGA	Colon Adenocarcinoma	0.0870	0.0570	8.0e-07	0.129	0.112	0.105	NA	0.111	6.8e-08	5.2e-07	1.2e-06	NA	5.9e-07
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.1100	0.0707	8.2e-03	0.029	0.022	0.025	NA	0.026	3.1e-04	1.5e-03	6.8e-04	NA	5.4e-04
16	TCGA	Ovarian Serous Cystadenocarcinoma	0.0400	0.0370	6.9e-03	0.035	0.013	0.003	NA	0.019	2.1e-03	4.3e-02	2.0e-01	NA	1.8e-02
17	TCGA	Pancreatic Adenocarcinoma	0.1550	0.0950	1.3e-05	0.119	0.117	0.114	NA	0.107	1.1e-05	1.3e-05	1.7e-05	NA	3.2e-05
18	TCGA	Rectum Adenocarcinoma	0.3940	0.1790	3.6e-03	0.078	0.068	0.053	NA	0.019	6.9e-03	1.1e-02	2.2e-02	NA	1.2e-01
19	TCGA	Thyroid Carcinoma	0.0960	0.0630	2.7e-10	0.115	0.103	0.098	NA	0.107	2.6e-11	3.2e-10	8.5e-10	NA	1.3e-10

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Hair/balding pattern: Pattern 4	16.0	38.8	49.8	-6.5	-6.7	-7.0	-6.7	-6.7	-5.7	-5.1	-6.4	-6.1	-6.8	-6.3	-7.1	-6.9	-6.9	-3.6	-4.5	-6.0	-5.4	-6.7
Height	10.2	195.7	269.0	14.6	16.3	16.4	16.0	15.9	12.1	10.5	14.5	12.6	16.0	13.7	16.1	15.6	15.4	5.7	8.3	12.2	13.8	14.6
Comparative height size at age 10	10.0	55.2	75.2	7.9	8.4	8.7	8.3	8.2	6.6	5.4	7.6	6.8	8.5	7.6	8.5	8.3	8.2	3.3	4.7	6.7	7.2	7.8
Standing height	9.8	97.0	134.6	10.4	11.6	11.6	11.3	11.2	8.6	6.5	10.2	8.9	11.2	9.6	11.3	11.0	10.8	3.8	5.9	8.6	10.0	10.3
Sitting height	7.8	55.4	74.8	7.9	8.6	8.6	8.4	8.3	6.6	4.8	7.6	7.0	8.4	6.8	8.4	8.3	8.1	3.8	4.8	6.7	7.9	7.8
Headache pain in last month	7.2	12.4	14.7	-3.7	-3.8	-3.8	-3.8	-3.5	-3.4	-3.2	-3.5	-3.5	-3.7	-3.8	-3.8	-3.8	-3.8	-2.4	-2.8	-3.4	-3.0	-3.7
Alcohol drinker status: Never	6.6	7.9	11.0	3.1	3.3	3.3	3.2	3.1	2.5	2.1	2.6	2.7	3.0	2.7	3.1	3.1	2.9	1.6	1.6	2.4	3.3	2.9
Ever unenthusiastic/disinterested for a whole week	6.0	7.4	9.9	3.1	3.1	2.8	2.5	2.4	3.0	3.1	2.7	2.8	2.5	2.5	2.7	2.7	2.7	1.9	2.7	2.7	2.8	2.8
Heart disease (siblings)	5.4	6.6	12.0	2.9	3.0	2.6	2.3	2.3	2.9	3.5	2.8	2.5	2.4	1.6	2.5	2.6	2.6	1.9	2.7	2.7	1.8	2.5
Medication: Paracetamol	5.2	8.1	10.6	-3.2	-3.0	-3.0	-2.7	-2.6	-3.3	-2.2	-2.9	-3.2	-2.6	-2.1	-2.9	-2.9	-2.9	-2.8	-3.0	-3.1	-2.2	-3.1
Hair/balding pattern: Pattern 3	5.0	7.4	12.0	-3.1	-3.5	-3.4	-3.0	-2.8	-2.5	-2.5	-2.9	-2.2	-3.1	-2.2	-3.3	-3.1	-3.2	-0.4	-1.6	-2.3	-2.0	-2.8
Medication: Paracetamol	4.8	7.9	10.9	-3.0	-2.7	-2.8	-2.7	-2.6	-3.1	-2.1	-2.8	-3.3	-2.7	-2.3	-2.8	-2.9	-3.0	-3.2	-3.0	-3.3	-1.6	-3.1
Trunk fat-free mass	4.7	26.9	41.5	5.6	6.1	6.2	5.9	5.9	4.5	3.0	5.3	4.5	5.8	4.9	5.9	5.7	5.5	1.6	3.0	4.2	6.4	5.3
Trunk predicted mass	4.7	26.6	41.0	5.5	6.1	6.1	5.9	5.9	4.5	2.9	5.3	4.5	5.8	4.9	5.9	5.7	5.5	1.7	3.0	4.2	6.4	5.3
Emphysema/chronic bronchitis	4.4	5.0	12.0	2.5	2.3	2.4	2.1	2.2	2.4	2.2	2.4	2.1	2.1	2.2	2.1	2.2	1.9	1.4	2.0	1.9	3.5	2.2
Whole body fat-free mass	4.3	24.3	40.6	5.3	5.8	5.9	5.7	5.6	4.3	2.9	5.0	4.2	5.6	4.5	5.6	5.5	5.2	1.4	2.8	3.9	6.4	5.0
Supplements: Fish oil (including cod liver oil)	4.3	5.6	9.6	-2.6	-1.8	-2.1	-1.9	-1.8	-2.9	-2.0	-2.2	-2.7	-1.9	-2.1	-2.1	-2.2	-2.2	-2.8	-3.1	-2.7	-2.3	-2.5
Basal metabolic rate	4.1	22.9	38.7	5.2	5.6	5.7	5.4	5.4	4.3	2.9	4.9	4.1	5.4	4.4	5.4	5.3	5.1	1.5	2.9	3.8	6.2	4.9
Whole body water mass	4.0	22.6	39.0	5.2	5.6	5.7	5.4	5.4	4.2	2.8	4.9	4.1	5.4	4.3	5.4	5.2	5.0	1.4	2.8	3.7	6.2	4.9
Hearing difficulty/problems with background noise	3.8	6.0	7.4	-2.6	-2.3	-2.7	-2.7	-2.5	-2.5	-2.1	-2.6	-2.7	-2.5	-1.9	-2.6	-2.6	-2.6	-2.4	-2.1	-2.6	-1.6	-2.6
Leg fat-free mass (left)	3.7	19.5	35.8	4.8	5.2	5.3	5.1	5.1	3.8	2.6	4.5	3.6	5.1	3.8	5.1	4.9	4.7	1.0	2.4	3.3	6.0	4.5
Leg predicted mass (left)	3.7	19.6	35.6	4.8	5.2	5.3	5.1	5.1	3.8	2.7	4.5	3.6	5.1	3.9	5.1	4.9	4.7	1.0	2.5	3.4	6.0	4.5
Leg predicted mass (right)	3.6	19.1	37.1	4.8	5.3	5.3	5.0	4.9	3.7	2.5	4.5	3.6	5.0	3.7	5.0	4.8	4.6	1.0	2.3	3.2	6.1	4.5
Leg fat-free mass (right)	3.5	18.9	37.2	4.8	5.3	5.3	5.0	4.9	3.7	2.5	4.4	3.5	5.0	3.7	5.0	4.8	4.5	0.9	2.3	3.2	6.1	4.4
Coronary Artery Disease (CAD)	3.4	4.1	6.5	2.0	2.5	2.3	2.1	2.3	1.6	1.6	2.2	2.1	2.3	1.3	2.1	2.3	2.1	0.0	2.2	2.2	2.5	0.0
Illnesses of siblings	3.4	4.8	7.1	-2.3	-2.3	-2.4	-2.6	-2.7	-2.0	-2.4	-2.2	-1.8	-2.6	-1.7	-2.4	-2.4	-2.4	-0.7	-1.6	-1.9	-2.0	-2.1
Arm fat-free mass (left)	3.4	17.1	29.3	4.5	4.7	4.8	4.6	4.5	3.9	2.5	4.3	3.7	4.5	3.6	4.6	4.5	4.3	1.8	2.8	3.4	5.4	4.3
Prostate Cancer	3.3	4.7	7.2	-2.3	-2.7	-2.6	-2.6	-2.7	-1.8	-1.3	-2.3	-2.4	-2.6	-1.3	-2.5	-2.5	-2.4	0.0	-1.0	-1.9	-1.7	-2.2
Bilateral oophorectomy (both ovaries removed)	3.3	3.8	6.7	2.2	2.3	2.3	1.8	2.0	1.9	1.4	2.2	1.9	1.9	2.2	2.0	2.0	1.9	1.3	1.3	1.6	2.6	1.9
Pulse rate, automated reading	3.3	10.6	16.6	-3.4	-4.0	-3.8	-3.8	-3.9	-2.7	-2.2	-3.2	-2.9	-3.8	-2.8	-3.7	-3.6	-3.4	-1.3	-1.8	-2.7	-4.1	-3.3
Arm predicted mass (left)	3.3	16.9	29.9	4.5	4.7	4.7	4.5	4.4	3.9	2.5	4.3	3.8	4.4	3.7	4.5	4.5	4.2	1.9	2.9	3.5	5.5	4.3
Heel bone mineral density (BMD) T-score, automated (right)	3.2	7.3	12.9	-2.8	-3.0	-2.9	-2.7	-2.8	-2.5	-3.6	-2.8	-2.6	-2.8	-1.2	-2.9	-2.9	-2.8	-2.0	-2.0	-2.4	-3.0	-2.8
Qualifications: None of the above	3.1	6.7	10.5	2.5	2.2	2.5	2.8	2.8	2.5	3.2	2.8	2.2	2.8	2.1	2.7	2.7	2.8	1.3	2.4	2.4	2.9	2.6
Medication: Ibuprofen	3.1	3.8	6.5	-2.1	-1.9	-1.7	-1.4	-1.5	-2.4	-1.1	-2.1	-2.3	-1.4	-2.2	-1.7	-1.8	-1.8	-2.2	-2.5	-2.2	-1.6	-2.0
Eye problems/disorders: Glaucoma	3.1	3.7	4.6	-2.0	-2.1	-2.1	-2.1	-2.1	-1.9	-1.7	-2.0	-1.9	-2.0	-1.2	-2.1	-2.1	-2.2	-1.3	-1.6	-2.0	-1.5	-2.1
Weight	2.8	13.8	25.0	4.0	4.1	4.3	4.1	4.0	3.4	2.5	3.8	3.2	4.1	3.7	4.2	4.1	3.9	1.2	2.4	3.0	5.0	3.9
Arm fat-free mass (right)	2.8	14.4	26.8	4.2	4.5	4.4	4.2	4.1	3.5	2.3	4.0	3.3	4.1	3.4	4.2	4.1	3.9	1.4	2.5	3.1	5.2	3.9
Arm predicted mass (right)	2.8	14.2	26.5	4.1	4.3	4.3	4.1	4.0	3.5	2.3	4.0	3.4	4.1	3.2	4.1	4.1	3.9	1.6	2.6	3.1	5.1	3.9
Glaucoma (self-reported)	2.6	3.0	4.0	-1.9	-1.9	-1.8	-1.7	-1.6	-2.0	-1.1	-1.7	-2.0	-1.6	-1.4	-1.8	-1.8	-1.9	-1.6	-1.9	-2.0	-1.2	-2.0
Mineral and other dietary supplements	2.6	3.5	6.0	2.0	1.6	1.9	1.8	1.7	2.1	1.3	1.6	2.2	1.7	1.8	1.8	1.9	1.8	2.4	2.0	2.1	1.7	2.0
Chronic bronchitis/emphysema (mother)	2.5	2.9	4.2	-1.9	-2.0	-1.7	-2.0	-1.8	-1.8	-2.0	-1.7	-1.7	-1.9	-1.2	-1.7	-1.8	-1.7	-1.3	-1.5	-1.7	-1.2	-1.6
Medication for pain relief, constipation, heartburn	2.5	4.2	5.6	2.1	1.9	2.0	2.0	1.9	2.3	1.5	2.2	2.3	2.0	1.9	2.0	2.1	2.2	2.0	2.4	2.3	1.6	2.3
Heart disease (mother)	2.5	3.1	6.5	1.7	1.6	1.4	1.4	1.4	1.9	2.5	1.9	2.0	1.6	0.6	1.7	1.8	1.9	1.9	2.2	2.1	1.0	1.8
Qualifications: NVQ or HND or HNC or equivalent	2.5	3.1	5.6	-1.7	-1.4	-1.7	-1.9	-1.7	-1.8	-2.4	-1.8	-1.7	-1.8	-1.1	-1.8	-1.8	-1.9	-1.1	-1.9	-1.9	-1.5	-1.9
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.1	6.4	-1.8	-1.4	-1.4	-1.2	-1.3	-2.2	-1.1	-1.9	-2.1	-1.2	-2.0	-1.5	-1.6	-1.7	-2.3	-2.5	-2.2	-1.0	-1.9
Migraine (self-reported)	2.4	3.0	6.5	-2.1	-2.5	-2.2	-1.9	-1.9	-1.7	-1.2	-2.0	-1.2	-1.9	-1.4	-2.0	-1.9	-2.0	-0.0	-1.0	-1.4	-1.1	-1.7
HbA1C	2.3	2.6	4.7	-1.7	-1.2	-1.3	-1.2	-1.2	-2.0	-1.9	-1.6	-1.9	-1.3	-0.6	-1.5	-1.5	-1.6	-2.2	-2.1	-2.0	-1.1	-1.6
Ever had hysterectomy (womb removed)	2.3	2.6	4.6	1.7	1.7	1.5	1.3	1.3	1.7	1.2	1.7	1.9	1.3	1.7	1.3	1.5	1.3	2.1	1.5	1.5	2.1	1.6
Forced vital capacity (FVC), Best measure	2.3	8.3	13.0	3.0	3.5	3.6	3.4	3.4	2.3	0.9	3.0	2.2	3.5	3.1	3.5	3.3	3.3	-0.1	1.3	2.2	3.2	2.9
Myopia	2.3	3.3	6.9	2.0	2.6	2.3	2.1	2.2	1.4	1.5	1.6	1.7	2.1	1.2	2.2	2.1	2.0	0.9	0.5	1.5	1.4	1.8
Medication: Atenolol	2.2	2.7	4.4	1.4	1.6	1.3	1.8	1.8	1.5	2.1	1.7	1.8	1.8	1.3	1.6	1.6	1.7	1.8	1.5	1.8	1.3	1.6
Leg pain on walking	2.1	2.6	4.7	1.8	1.6	1.3	1.2	1.2	2.0	1.6	1.6	1.8	1.4	1.3	1.4	1.6	1.5	1.8	2.2	1.7	1.8	1.6
Mouth/teeth dental problems: Mouth ulcers	2.1	3.4	6.7	1.9	2.1	2.2	2.1	2.2	1.5	1.1	1.9	1.6	2.2	1.3	2.1	2.1	1.9	0.6	0.9	1.4	2.6	1.9
Qualifications: College or University degree	2.0	6.3	9.1	-2.5	-2.3	-2.5	-2.8	-2.9	-2.3	-2.4	-2.7	-2.2	-3.0	-2.9	-2.8	-2.7	-2.8	-1.3	-2.0	-2.4	-2.0	-2.5
Diastolic blood pressure, automated reading	2.0	6.3	10.6	-2.8	-3.3	-3.0	-2.6	-2.7	-2.3	-1.8	-2.2	-2.2	-2.8	-2.9	-2.8	-2.7	-2.6	-0.9	-1.5	-2.1	-2.9	-2.6
Trunk fat mass	1.9	8.0	14.2	3.0	3.0	3.2	3.1	3.0	2.6	2.4	3.0	2.3	3.1	2.9	3.2	3.1	3.0	0.7	1.9	2.3	3.8	2.9
Heart attack	1.9	2.5	4.9	1.5	2.2	1.8	1.6	1.7	1.0	1.3	1.8	1.7	1.8	1.2	1.6	1.7	1.5	1.6	0.4	1.2	1.8	1.5
Qualifications: A levels/AS levels or equivalent	1.9	4.2	7.0	-2.0	-1.3	-1.8	-1.9	-1.9	-2.3	-2.3	-2.3	-1.9	-1.9	-2.6	-2.0	-2.0	-2.1	-1.4	-2.5	-2.2	-2.2	-2.1
Osteoarthritis (self-reported)	1.9	2.5	7.3	1.5	0.8	1.4	1.4	1.4	1.8	2.7	1.5	1.5	1.4	1.3	1.6	1.6	1.7	0.6	1.9	1.6	1.6	1.7
Average weekly beer plus cider intake	1.9	2.8	6.1	-1.7	-1.3	-1.4	-1.4	-1.1	-2.0	-2.0	-1.7	-2.0	-1.3	-0.5	-1.5	-1.5	-1.7	-2.5	-2.2	-2.2	-0.1	-1.8
Had other major operations	1.8	2.2	2.8	1.7	1.7	1.7	1.6	1.3	1.6	1.7	1.6	1.4	1.5	1.4	1.6	1.6	1.6	0.7	1.3	1.4	1.3	1.5
Forced vital capacity (FVC)	1.8	6.9	11.5	2.7	3.0	3.3	3.3	3.2	1.9	0.5	2.7	2.0	3.4	2.8	3.3	3.1	3.1	-0.0	1.0	2.1	2.3	2.7
Hip circumference	1.8	8.0	14.2	3.0	3.1	3.3	3.1	3.0	2.6	2.2	2.9	2.3	3.1	2.8	3.2	3.1	3.0	0.5	1.8	2.2	3.8	3.0
Prospective memory result	1.8	2.2	3.7	-1.8	-1.9	-1.6	-1.2	-1.3	-1.8	-1.3	-1.6	-1.8	-1.2	-0.8	-1.3	-1.4	-1.3	-1.6	-1.5	-1.5	-1.7	-1.5
Smoking status: Previous	1.8	2.7	5.5	1.5	1.4	1.4	1.7	1.5	1.6	1.4	1.9	1.7	1.6	2.3	1.6	1.6	1.6	1.5	1.6	1.6	1.8	1.6
Breast cancer (self-reported)	1.8	2.1	3.4	1.3	1.3	1.6	1.8	1.8	1.1	1.7	1.3	1.5	1.8	1.2	1.6	1.6	1.5	1.1	0.8	1.4	1.3	1.5
Hearing difficulty/problems: Yes	1.7	2.6	4.8	-1.6	-1.4	-1.5	-1.4	-1.4	-1.9	-2.2	-1.7	-1.8	-1.3	-1.1	-1.5	-1.5	-1.6	-1.8	-2.0	-2.0	-0.7	-1.8
Loud music exposure frequency	1.6	1.8	6.1	1.4	1.7	1.5	1.4	1.3	1.3	0.8	1.1	1.0	1.4	0.5	1.4	1.4	1.3	0.4	1.0	0.9	2.5	1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.6	3.3	6.6	2.0	2.3	2.2	1.9	2.0	1.6	0.6	2.1	1.7	2.0	1.4	1.9	1.9	1.7	0.8	1.1	1.5	2.6	1.9
Ever taken oral contraceptive pill	1.6	1.8	2.9	1.5	1.3	1.5	1.4	1.3	1.5	1.7	1.3	1.0	1.4	0.8	1.5	1.4	1.5	0.0	1.3	1.3	1.2	1.4
Number of treatments/medications taken	1.5	2.7	3.6	-1.9	-1.9	-1.9	-1.6	-1.7	-1.7	-1.0	-1.6	-1.7	-1.7	-1.6	-1.8	-1.8	-1.8	-1.4	-1.4	-1.8	-1.0	-1.8
Impedance of arm (right)	1.5	6.9	11.1	2.5	2.8	3.1	3.3	3.2	1.9	1.9	2.6	2.3	3.3	3.0	3.3	3.1	3.2	0.6	1.2	2.5	1.1	2.7
Qualifications: nursing, teaching	1.5	2.3	4.7	-1.6	-1.2	-1.6	-1.8	-1.7	-1.5	-2.2	-1.4	-1.4	-1.6	-1.1	-1.6	-1.6	-1.5	-0.9	-1.3	-1.4	-1.8	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	3.6	-1.4	-1.4	-1.3	-1.2	-1.2	-1.4	-0.7	-1.2	-1.7	-1.2	0.1	-1.4	-1.4	-1.4	-1.9	-1.3	-1.6	-0.6	-1.5
Hearing aid user	1.5	1.7	4.3	-1.2	-1.1	-1.3	-1.3	-1.2	-1.3	-2.1	-1.3	-1.3	-1.3	-0.2	-1.4	-1.4	-1.5	-0.9	-1.2	-1.4	-0.7	-1.4
Mean Putamen Volume	1.4	1.5	2.4	1.3	1.2	1.5	1.5	1.3	1.0	0.4	1.2	1.3	1.4	1.0	1.5	1.5	1.4	1.0	0.6	1.1	1.4	1.4
Heel T-Score	1.4	11.2	20.7	-2.9	-4.1	-4.2	-4.4	-4.4	-1.6	-3.0	-3.8	-2.3	-4.5	-2.1	-4.4	-4.0	-4.2	0.1	-0.0	-2.3	-2.0	-3.3
Age when periods started (menarche)	1.4	3.3	5.4	1.9	1.3	1.6	1.6	1.7	2.2	1.7	2.1	2.0	1.6	1.8	1.6	1.7	1.8	2.1	2.3	2.3	0.9	1.9
Heel bone mineral density (BMD) T-score, automated (left)	1.4	3.2	7.9	-1.8	-2.1	-1.9	-1.7	-1.8	-1.6	-2.8	-1.9	-1.6	-1.9	-0.4	-1.9	-1.9	-1.9	-1.1	-1.3	-1.5	-2.0	-1.8
Pulse rate	1.4	2.4	4.6	-1.5	-2.1	-1.9	-2.0	-1.9	-1.1	-0.6	-1.6	-1.1	-2.0	-1.4	-1.9	-1.8	-1.7	0.3	-0.5	-1.0	-2.0	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.4	7.3	2.2	2.7	2.7	2.5	2.5	1.5	0.4	2.1	1.4	2.6	2.5	2.6	2.4	2.4	-0.6	0.6	1.5	2.1	2.0
Medication: Allopurinol	1.4	1.9	3.2	-1.2	-1.3	-1.4	-1.6	-1.5	-1.1	-1.5	-1.5	-1.6	-1.6	-0.9	-1.4	-1.5	-1.5	-1.8	-0.8	-1.5	-0.7	-1.5
Age started oral contraceptive pill	1.4	1.7	2.7	1.3	1.3	1.2	1.3	1.2	1.3	1.4	1.4	1.3	1.2	1.6	1.3	1.3	1.3	1.1	1.3	1.4	1.1	1.3
Heart attack/myocardial infarction (self-reported)	1.4	1.8	3.6	1.2	1.9	1.5	1.4	1.5	0.7	1.0	1.5	1.5	1.6	1.0	1.3	1.4	1.2	1.6	0.2	1.0	1.7	1.2
Type 2 Diabetes (T2D) (2012)	1.3	1.5	2.3	-1.3	-1.3	-1.3	-1.2	-1.3	-1.2	-0.3	-1.5	-1.2	-1.3	-1.1	-1.5	-1.4	-1.5	-0.2	-0.8	-1.1	-1.1	-1.1
Vitamin and mineral supplements	1.3	1.8	2.6	1.4	0.9	1.3	1.4	1.3	1.4	0.9	1.1	1.6	1.4	0.8	1.3	1.4	1.3	1.5	1.5	1.5	1.5	1.5
High blood pressure (mother)	1.3	1.9	3.2	-1.5	-1.4	-1.4	-1.3	-1.3	-1.4	-1.1	-1.5	-1.4	-1.3	-1.8	-1.4	-1.4	-1.5	-1.0	-1.2	-1.4	-1.0	-1.4
Hair/balding pattern: Pattern 2	1.3	1.7	3.9	1.4	1.8	1.6	1.5	1.3	1.1	2.0	1.2	0.9	1.3	0.8	1.5	1.4	1.5	-0.0	0.7	1.0	0.9	1.3
Mouth/teeth dental problems	1.3	1.9	5.7	-1.3	-1.8	-1.8	-1.7	-1.8	-0.6	-0.7	-1.5	-0.6	-1.7	-0.8	-1.7	-1.6	-1.4	0.9	0.3	-0.3	-2.4	-1.2
Exposure to tobacco smoke outside home	1.3	1.7	3.1	-1.4	-1.8	-1.6	-1.3	-1.3	-1.1	-0.5	-1.3	-1.4	-1.3	-1.5	-1.5	-1.5	-1.4	-0.8	-0.7	-1.2	-1.1	-1.4
Osteoporosis (self-reported)	1.3	1.7	6.5	-1.1	-0.6	-0.8	-1.2	-1.1	-1.3	-0.2	-1.2	-1.7	-1.2	-0.2	-0.9	-1.2	-1.0	-2.5	-1.6	-1.5	-1.8	-1.3
Crohns Disease (2017)	1.2	2.6	7.1	1.5	1.3	1.3	1.4	1.3	1.7	2.1	1.4	1.7	1.2	2.7	1.3	1.3	1.3	1.9	1.7	1.7	1.1	1.6
Angina	1.2	1.5	4.3	1.3	2.1	1.5	1.4	1.4	0.9	0.8	1.3	1.3	1.4	0.8	1.4	1.4	1.4	0.9	0.3	1.1	0.5	1.2
Supplements: Glucosamine	1.2	1.6	5.1	-1.2	-1.1	-1.4	-1.3	-1.2	-1.0	0.1	-1.0	-1.7	-1.3	-0.6	-1.3	-1.4	-1.2	-2.3	-0.6	-1.3	-1.1	-1.4
Allergy	1.2	2.8	4.0	-1.8	-1.9	-1.8	-1.8	-1.8	-1.6	-1.4	-2.0	-1.5	-1.8	-1.7	-1.8	-1.8	-1.8	-0.8	-1.3	-1.6	-1.4	-1.8
Worrier / anxious feelings	1.2	2.3	5.4	-1.4	-1.2	-1.5	-1.4	-1.3	-1.5	-1.4	-1.5	-1.8	-1.4	0.1	-1.4	-1.5	-1.5	-2.3	-1.4	-1.6	-1.5	-1.7
Forced expiratory volume in 1-second (FEV1)	1.2	4.0	7.4	1.9	2.4	2.6	2.7	2.6	1.2	0.2	1.8	1.3	2.7	2.3	2.6	2.3	2.3	-0.5	0.2	1.4	1.5	1.9
Medication: Amlodipine	1.2	1.7	3.5	-1.5	-1.5	-1.5	-1.4	-1.4	-1.2	-0.5	-1.5	-1.2	-1.5	-1.9	-1.5	-1.5	-1.6	-0.6	-0.7	-1.3	-0.2	-1.2
Average weekly champagne plus white wine intake	1.2	1.7	4.8	-1.3	-1.1	-1.2	-1.2	-1.2	-1.3	-1.4	-1.3	-1.1	-1.2	-2.2	-1.4	-1.3	-1.5	-0.6	-1.2	-1.3	-0.5	-1.3
Ever smoked	1.2	2.1	4.3	-1.8	-2.1	-2.0	-1.5	-1.4	-1.3	-0.5	-1.3	-1.6	-1.5	-1.0	-1.7	-1.7	-1.6	-1.1	-0.7	-1.3	-1.1	-1.7
Bipolar Disorder or Schizophrenia	1.1	2.6	7.4	-1.8	-1.3	-1.0	-1.0	-1.2	-2.3	-1.5	-1.5	-2.1	-1.0	-0.5	-1.1	-1.3	-1.2	-2.5	-2.7	-2.1	-1.3	-1.4
Systolic Blood Pressure	1.1	5.7	13.0	2.2	1.5	1.8	2.0	2.0	2.7	2.8	2.4	2.9	1.8	1.1	2.0	2.2	2.4	3.6	3.2	3.1	0.4	2.6
Medication: Metformin	1.1	1.5	3.2	-0.9	-1.4	-1.5	-1.8	-1.7	-0.2	-0.6	-1.1	-0.0	-1.7	-1.4	-1.6	-1.3	-1.5	1.7	0.6	-0.4	-0.2	-0.8
Impedance of leg (right)	1.1	5.2	8.9	2.0	1.7	1.9	2.0	2.1	2.4	2.4	2.3	2.6	2.1	2.6	2.2	2.2	2.5	2.7	2.6	3.0	-0.1	2.4
Eye problems/disorders: None of the above	1.1	1.3	1.8	1.0	0.9	1.0	1.3	1.3	1.0	0.9	0.9	1.3	1.2	1.1	1.2	1.2	1.2	1.2	1.1	1.2	1.1	1.2
Whole body fat mass	1.1	4.7	10.4	2.3	2.2	2.4	2.3	2.2	2.1	1.9	2.3	1.7	2.4	2.1	2.4	2.3	2.2	0.4	1.6	1.7	3.2	2.2
Commuting to job workplace: Cycle	1.1	1.3	2.8	1.3	1.3	1.1	0.9	0.9	1.4	-0.2	1.2	1.4	0.9	1.3	0.9	1.0	0.9	1.7	1.3	1.3	1.0	1.2
LDL Cholesterol	1.0	1.6	2.5	-1.6	-1.3	-1.4	-1.3	-1.3	-1.6	-1.3	-1.5	-1.2	-1.3	-0.8	-1.4	-1.4	-1.4	-0.8	-1.0	-1.3	-0.5	-1.2
Schizophrenia (2014)	1.0	2.3	5.1	-1.8	-1.4	-1.3	-1.1	-1.3	-2.1	-0.9	-1.6	-1.9	-1.1	-1.0	-1.2	-1.4	-1.2	0.0	-2.2	-1.9	-2.0	-1.7
Waist circumference	1.0	3.5	8.6	2.0	2.2	2.3	2.1	2.0	1.4	1.3	1.9	1.4	2.1	2.1	2.1	2.1	1.9	0.1	0.6	1.1	2.9	1.8
Falls in the last year	1.0	1.4	2.3	-1.3	-1.4	-1.3	-1.4	-1.2	-1.2	-1.5	-1.1	-1.0	-1.3	-0.9	-1.4	-1.3	-1.4	0.0	-1.0	-1.2	-0.3	-1.2
Impedance of arm (left)	1.0	4.4	7.5	1.9	2.2	2.5	2.6	2.6	1.5	1.8	2.1	1.8	2.7	2.2	2.6	2.5	2.6	0.4	1.0	2.0	1.0	2.2
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.4	1.0	1.5	1.5	1.5	1.5	0.4	0.5	1.2	0.2	1.6	0.1	1.5	1.3	1.3	-1.3	-0.3	0.3	1.4	0.9
Shortness of breath walking on level ground	1.0	1.2	5.6	0.8	0.7	0.6	0.9	0.9	0.9	0.8	0.9	1.4	0.9	0.9	0.8	1.0	0.9	2.4	1.1	1.3	1.0	1.1
Schizophrenia (2018)	0.9	1.9	4.8	-1.6	-1.3	-1.0	-0.9	-1.2	-2.0	-1.0	-1.4	-1.6	-1.0	-0.7	-1.0	-1.2	-1.1	-1.6	-2.2	-1.6	-1.5	-1.3
Neuroticism (2016)	0.9	1.3	3.5	1.0	1.4	1.2	1.1	1.3	0.7	0.8	1.0	1.0	1.3	1.9	1.1	1.2	1.0	0.5	0.4	0.8	1.8	0.9
Systolic blood pressure, automated reading	0.9	2.6	5.0	1.4	0.8	1.1	1.5	1.4	1.8	2.1	1.8	1.9	1.4	1.2	1.5	1.6	1.8	2.2	2.1	2.2	-0.5	1.7
Trunk fat percentage	0.9	3.6	6.3	1.9	1.8	2.0	2.0	1.9	1.8	2.0	2.0	1.5	2.1	1.9	2.1	2.0	2.0	0.4	1.4	1.6	2.5	1.9
Current tobacco smoking	0.9	1.4	4.2	-1.2	-1.3	-1.4	-1.5	-1.2	-0.8	0.4	-0.9	-1.1	-1.5	-2.1	-1.4	-1.4	-1.4	-0.5	-0.4	-1.0	-0.3	-1.2
High blood pressure (siblings)	0.9	1.3	2.1	1.2	1.2	1.4	1.5	1.4	1.0	1.0	1.0	0.9	1.3	1.0	1.3	1.3	1.2	0.3	0.6	0.9	1.0	1.1
Risk taking	0.9	1.3	5.2	-0.8	-0.7	-0.9	-0.8	-0.8	-1.0	-1.5	-1.0	-1.7	-0.8	-0.7	-0.9	-1.0	-1.0	-2.3	-1.1	-1.4	-0.4	-1.3
Triglycerides	0.8	1.4	2.2	-1.4	-1.1	-1.2	-1.0	-1.1	-1.4	-1.1	-1.5	-1.1	-1.4	-1.3	-1.3	-1.3	-1.4	-0.4	-0.9	-1.1	-0.6	-1.1
Hair Pigment	0.8	22.0	25.7	4.8	4.4	4.7	4.8	4.8	5.0	4.7	5.0	4.6	4.8	4.2	4.9	4.9	5.1	3.0	4.9	4.8	4.3	5.0
Severe depression (siblings)	0.8	0.9	1.9	-0.7	-1.0	-1.1	-1.4	-1.1	-0.3	-0.4	-0.8	-0.7	-1.3	-1.3	-1.2	-1.1	-1.0	-0.3	0.1	-0.5	-1.3	-1.0
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	3.3	0.8	0.2	0.3	0.1	0.2	1.3	1.6	0.7	1.3	0.2	0.5	0.4	0.5	0.6	1.8	1.8	1.3	-0.0	0.9
Medication: Lansoprazole	0.8	0.9	1.9	-1.2	-1.4	-1.1	-0.8	-0.9	-1.0	-1.0	-0.8	-1.1	-0.9	-0.4	-1.1	-1.0	-1.1	-0.8	-0.7	-1.1	-0.3	-1.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.4	-0.7	-0.1	-0.6	-1.0	-1.1	-1.1	-1.9	-1.2	-1.1	-1.0	-0.6	-1.0	-1.0	-1.2	-1.4	-1.5	-1.3	-1.0	-1.1
Mean time to correctly identify matches	0.8	1.5	3.4	-1.3	-1.0	-1.0	-0.9	-0.9	-1.6	-1.8	-1.2	-1.4	-0.7	-0.8	-0.9	-1.0	-1.1	-1.7	-1.8	-1.5	-0.5	-1.4
Leg fat mass (right)	0.8	3.0	7.3	1.9	1.7	1.8	1.7	1.6	1.8	1.5	1.8	1.6	1.7	1.8	1.8	1.8	1.7	0.9	1.6	1.5	2.7	1.8
Fractured/broken bones in last 5 years	0.8	1.0	2.0	1.1	1.3	1.4	1.1	1.0	0.7	-0.5	1.1	0.9	1.0	1.4	1.2	1.2	1.1	0.2	0.1	0.7	0.9	1.1
Impedance of whole body	0.8	3.9	5.6	1.8	1.8	2.0	2.1	2.1	1.8	2.0	2.1	2.0	2.2	2.1	2.2	2.1	2.3	1.4	1.7	2.4	0.2	2.1
HDL Cholesterol	0.7	1.1	2.6	-0.9	-0.9	-1.1	-1.5	-1.3	-0.8	-1.1	-0.6	-1.0	-1.0	-1.6	-1.1	-1.1	-1.1	-0.8	-0.8	-1.0	-0.8	-1.2
Chronotype (morning person)	0.7	1.6	4.8	1.0	0.8	1.0	1.1	1.0	1.2	0.8	1.0	1.5	1.0	2.2	1.0	1.1	1.0	1.8	1.3	1.3	1.5	1.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.7	-0.6	-0.4	-0.8	-1.4	-1.1	-0.3	-1.6	-0.6	-0.5	-1.2	-1.2	-1.1	-1.0	-1.1	0.2	-0.1	-0.7	0.0	-0.7
Medication: Co-codamol	0.7	0.8	2.3	-0.9	-0.6	-0.6	-0.5	-0.6	-1.3	-0.3	-0.9	-1.1	-0.4	-0.8	-0.6	-0.7	-0.7	-1.5	-1.5	-1.1	-0.6	-0.9
Townsend deprivation index at recruitment	0.7	1.0	2.8	1.0	0.8	0.9	1.0	0.9	1.0	1.6	1.0	1.0	0.8	0.1	0.9	0.9	0.8	1.1	1.0	0.9	1.7	1.1
Relative age voice broke	0.7	1.1	2.7	-1.2	-1.4	-1.3	-1.2	-1.0	-0.9	-0.0	-0.9	-0.9	-1.1	-1.3	-1.1	-1.1	-1.0	-0.3	-0.5	-0.7	-1.6	-1.0
Diabetes (self-reported)	0.7	1.1	2.6	-0.9	-1.1	-1.1	-1.4	-1.4	-0.5	-1.5	-1.0	0.0	-1.2	-1.4	-1.2	-1.0	-1.1	1.6	-0.0	-0.4	-0.4	-0.6
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.4	-0.8	-0.3	-0.4	-0.4	-0.4	-1.2	-1.1	-0.7	-1.3	-0.6	-0.4	-0.6	-0.7	-0.9	-1.8	-1.5	-1.5	0.6	-0.9
Pulse wave peak to peak time	0.7	0.9	1.7	1.2	1.3	1.3	1.0	0.9	0.9	0.2	1.0	0.7	1.1	0.1	1.2	1.1	1.1	-0.2	0.6	0.8	0.6	1.0
Angina (self-reported)	0.7	0.9	2.8	0.9	1.7	1.1	1.0	1.0	0.6	0.5	0.9	1.0	1.1	0.7	1.1	1.1	1.1	0.8	0.1	0.8	0.2	0.9
Illness, injury, bereavement, stress in last 2 years	0.7	0.9	2.8	-1.1	-1.0	-0.8	-0.9	-0.7	-1.1	-1.7	-1.0	-0.8	-0.8	-0.4	-0.9	-0.9	-0.9	-0.3	-1.1	-0.9	-0.8	-0.8
Long-standing illness, disability or infirmity	0.7	1.0	1.5	-1.1	-0.9	-1.2	-1.2	-1.1	-1.0	-0.4	-0.9	-1.1	-1.1	-0.7	-1.2	-1.2	-1.2	-0.8	-0.8	-1.1	-0.4	-1.2
Miserableness	0.7	1.3	3.7	1.2	1.1	0.9	1.0	1.1	1.5	1.3	1.3	0.9	1.0	0.3	0.9	1.0	0.9	0.6	1.7	1.1	1.9	1.0
Irritability	0.7	1.2	2.8	1.0	1.3	1.4	1.5	1.7	0.6	0.4	1.1	0.6	1.7	0.9	1.4	1.3	1.4	-0.5	0.2	0.8	0.9	1.0
Bipolar Disorder (2018)	0.6	0.9	4.0	-0.8	-0.4	-0.3	-0.4	-0.5	-1.2	-1.3	-0.6	-1.4	-0.4	0.1	-0.5	-0.7	-0.6	-2.0	-1.6	-1.2	-0.2	-0.7
Reaction Time	0.6	1.2	3.6	-1.2	-1.2	-0.9	-0.9	-0.8	-1.4	-1.9	-1.2	-1.1	-0.6	-0.7	-0.9	-0.9	-0.9	-1.2	-1.5	-1.2	-0.6	-1.1
Lupus	0.6	0.9	2.0	-0.9	-1.4	-1.1	-1.0	-1.1	-0.6	-0.8	-1.3	-0.8	-1.2	-0.9	-1.1	-1.1	-1.1	-0.2	-0.3	-0.7	-0.4	-0.7
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.5	-0.8	-1.1	-1.2	-1.6	-1.4	-0.3	-1.5	-1.0	0.1	-1.4	-1.3	-1.3	-1.1	-1.2	1.6	0.3	-0.3	-0.6	-0.7
Impedance of leg (left)	0.6	3.0	5.7	1.5	1.4	1.3	1.3	1.3	1.8	1.8	1.9	2.1	1.5	2.1	1.6	1.6	1.8	2.2	2.1	2.4	-0.5	1.8
Alcohol usually taken with meals	0.6	1.0	1.7	1.0	0.8	1.0	1.0	0.9	1.0	0.8	0.8	1.2	0.9	-0.3	1.0	1.0	1.0	1.3	1.0	1.1	0.9	1.2
Pain all over the body in last month	0.6	0.6	2.1	0.9	1.0	0.7	0.6	0.6	0.8	1.1	1.2	0.6	0.7	0.4	0.7	0.7	0.7	0.4	0.8	0.6	1.5	0.6
Pulse wave reflection index	0.6	0.8	1.3	-1.1	-0.9	-1.0	-0.7	-0.6	-1.0	-0.7	-1.1	-0.8	-0.8	-0.4	-1.0	-1.0	-1.1	-0.5	-0.9	-1.0	0.2	-0.9
Number of children fathered	0.6	0.7	3.2	0.6	0.4	0.6	0.7	0.6	0.8	1.8	0.8	0.4	0.8	1.0	0.8	0.7	0.9	-0.2	1.0	0.7	0.7	0.8
Medication: Omeprazole	0.6	0.7	1.8	0.8	1.2	1.1	0.9	1.0	0.3	0.8	0.8	0.3	1.0	0.5	1.0	0.9	0.8	-0.9	-0.2	0.2	1.3	0.7
Handedness (chirality/laterality): Left-handed	0.6	0.7	1.5	0.6	0.7	0.8	1.2	1.0	0.4	1.1	0.8	0.7	1.1	1.0	0.9	0.9	1.0	0.5	0.3	0.8	0.1	0.8
Diabetes diagnosed by doctor	0.6	0.9	2.7	-0.7	-1.1	-1.1	-1.4	-1.4	-0.2	-1.0	-0.8	0.2	-1.3	-1.2	-1.1	-0.9	-1.0	1.6	0.5	-0.1	-0.6	-0.5
Smoking status: Current	0.6	1.0	4.0	-0.9	-1.1	-1.1	-1.2	-1.0	-0.7	0.5	-0.7	-0.8	-1.2	-2.0	-1.2	-1.1	-1.2	-0.1	-0.3	-0.8	-0.1	-0.9
Mother’s age at death	0.6	0.8	1.5	-0.9	-1.2	-1.0	-0.9	-0.7	-0.8	-0.4	-1.0	-1.0	-1.0	-0.7	-0.9	-0.9	-0.9	-1.0	-0.6	-0.9	-0.6	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	3.3	0.8	0.6	0.4	0.8	0.7	1.0	-0.1	0.7	1.1	0.6	1.3	0.4	0.6	0.4	1.8	1.2	1.0	0.9	0.7
Alzheimer’s Disease (in mother)	0.5	0.6	1.5	0.8	0.5	0.8	0.8	0.8	0.8	0.4	0.5	0.8	0.7	0.9	0.8	0.8	0.7	0.7	0.6	0.7	1.2	0.9
Irritable Bowel Disease (IBD)	0.5	1.1	6.9	1.1	0.7	0.8	0.9	0.8	1.2	1.2	0.8	0.9	0.7	2.6	0.8	0.8	0.9	0.8	1.2	1.1	0.3	0.9
Allergy or Eczema	0.5	1.2	2.3	0.9	1.2	1.3	1.5	1.5	0.6	1.1	1.2	0.5	1.5	0.4	1.5	1.3	1.5	-0.7	0.3	0.7	0.5	1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.6	0.4	0.6	0.8	1.2	1.3	0.2	0.5	0.7	0.5	1.2	1.2	1.1	1.0	1.0	-0.5	-0.1	0.5	0.9	0.7
Number of incorrect matches in round	0.5	0.8	1.2	0.9	0.7	0.8	1.0	1.0	0.9	0.8	1.0	0.8	1.1	0.5	1.0	1.0	1.0	0.5	0.8	0.9	1.0	0.8
Medication: Ramipril	0.5	0.6	1.5	-0.5	-0.7	-0.9	-1.2	-1.2	-0.2	-0.1	-0.5	-0.3	-1.1	-0.7	-1.0	-0.9	-0.8	0.5	0.2	-0.3	-1.2	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.5	0.8	1.1	1.1	0.7	0.7	0.5	1.2	0.9	0.6	0.7	0.2	0.9	0.8	0.8	0.0	0.1	0.5	0.5	0.8
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.7	0.8	0.4	0.3	0.3	0.2	1.1	0.9	0.7	0.9	0.1	0.2	0.2	0.4	0.2	1.2	1.4	0.7	1.6	0.6
Gout (self-reported)	0.5	0.7	1.4	-0.6	-0.9	-0.8	-1.0	-1.0	-0.5	-0.7	-0.9	-0.9	-0.9	0.1	-0.8	-0.9	-0.7	-1.2	-0.3	-0.8	-0.7	-0.9
Number of full brothers	0.5	0.7	2.7	0.8	0.5	0.6	0.4	0.6	0.9	1.0	0.9	1.2	0.5	-0.2	0.7	0.7	0.8	1.6	0.9	1.0	-0.2	0.9
Medication: Seretide 50 evohaler	0.5	0.6	2.4	-0.6	-0.3	-0.5	-0.6	-0.4	-0.8	-1.1	-0.4	-1.0	-0.4	-0.9	-0.5	-0.6	-0.5	-1.6	-0.9	-0.8	-0.9	-0.7
Family relationship satisfaction	0.5	0.6	1.7	0.7	0.7	0.9	1.1	1.0	0.5	0.6	0.8	0.2	0.9	1.3	0.9	0.8	0.8	-0.3	0.2	0.4	1.1	0.7
Friendships satisfaction	0.5	0.6	1.3	1.0	1.1	0.9	0.9	0.7	0.8	0.8	0.9	0.2	0.8	0.9	0.9	0.8	0.8	-0.7	0.5	0.4	0.9	0.6
Medication: Lisinopril	0.5	0.6	2.5	-0.7	-0.3	-0.3	-0.2	-0.3	-1.0	-1.6	-0.5	-1.0	-0.2	-0.3	-0.3	-0.4	-0.4	-1.5	-1.3	-1.0	-0.0	-0.6
Supplements: Calcium	0.5	0.5	1.2	0.8	0.9	0.7	0.6	0.7	0.9	0.3	1.1	0.6	0.7	0.0	0.8	0.7	0.9	0.0	0.9	0.8	0.2	0.7
Leg fat mass (left)	0.5	2.1	5.7	1.6	1.4	1.5	1.3	1.2	1.6	1.3	1.5	1.2	1.3	1.6	1.4	1.4	1.4	0.6	1.4	1.2	2.4	1.5
Major Depression (MDD)	0.4	0.5	2.5	0.4	0.7	0.8	1.1	1.0	0.2	0.9	0.5	0.2	0.8	1.6	0.8	0.6	0.8	0.0	-0.1	0.4	-0.2	0.6
Cardiovascular Disease	0.4	1.4	4.2	1.2	0.8	0.7	0.5	0.5	1.6	1.5	1.3	1.4	0.4	1.2	0.7	0.8	0.8	1.7	2.0	1.4	1.0	1.2
Average weekly spirits intake	0.4	0.5	2.3	-0.8	-1.2	-1.0	-0.7	-0.6	-0.5	-0.3	-0.3	-0.4	-0.6	-0.6	-0.9	-0.8	-0.7	0.4	-0.1	-0.2	-1.5	-0.7
Qualifications: CSEs or equivalent	0.4	0.6	1.3	0.7	0.7	0.8	1.0	1.1	0.6	0.3	0.8	0.7	1.1	0.2	0.9	0.9	1.0	0.3	0.4	0.8	-0.3	0.7
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.4	0.8	1.0	1.0	1.0	1.0	0.8	0.7	1.1	0.9	1.0	0.7	1.1	1.1	1.2	0.4	0.7	1.0	0.0	1.1
Multivitamins +/- minerals	0.4	0.5	1.7	-0.8	-0.5	-0.5	-0.6	-0.6	-0.8	-0.5	-0.5	-0.9	-0.5	-0.2	-0.5	-0.6	-0.5	-1.3	-0.9	-0.9	-0.3	-0.7
Chronic bronchitis/emphysema (father)	0.4	0.4	0.9	-0.7	-0.8	-0.7	-0.7	-0.7	-0.5	-0.5	-0.4	-0.7	-0.8	-0.9	-0.7	-0.6	-0.7	-1.0	-0.2	-0.7	0.2	-0.5
Number of live births	0.4	0.6	1.5	0.5	0.8	1.0	1.0	0.8	0.0	1.0	0.4	0.0	1.0	-0.6	1.0	0.8	0.8	-1.2	-0.5	-0.1	1.2	0.6
Medication: Cholesterol lowering	0.4	0.6	1.3	-0.7	-0.5	-1.0	-1.1	-1.1	-0.5	-0.5	-0.7	-0.4	-1.1	-0.8	-1.1	-0.9	-1.0	0.5	-0.2	-0.6	-0.3	-0.8
Arm fat mass (right)	0.4	1.8	6.2	1.4	1.3	1.5	1.4	1.4	1.2	0.9	1.3	0.8	1.4	1.4	1.5	1.4	1.3	-0.2	0.8	0.8	2.5	1.3
Blood clot in the leg (DVT)	0.4	0.6	3.5	0.6	0.4	0.1	0.6	0.5	0.9	-0.2	0.5	1.0	0.4	0.9	0.2	0.4	0.2	1.9	1.2	0.9	0.7	0.5
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.5	-0.6	-0.1	-0.5	-0.4	-0.4	-0.8	-0.9	-0.6	-0.8	-0.2	-1.2	-0.4	-0.4	-0.4	-1.1	-1.0	-0.8	-0.3	-0.7
Age at first live birth	0.4	0.7	1.4	-0.6	-0.7	-1.0	-1.2	-1.1	-0.3	-1.1	-0.7	-0.8	-1.2	-0.2	-1.1	-1.1	-1.1	-0.2	-0.0	-0.6	-0.5	-0.9
Suffer from ‘nerves’	0.4	0.7	1.7	0.8	0.9	0.7	0.7	0.8	0.8	0.9	0.8	0.9	0.7	0.9	0.6	0.7	0.6	1.1	0.7	0.7	1.3	0.8
Age at last live birth	0.4	0.5	1.2	-0.6	-0.3	-0.5	-0.6	-0.6	-0.8	-0.8	-0.6	-1.0	-0.5	-0.2	-0.7	-0.7	-0.8	-1.1	-1.0	-1.0	0.3	-0.8
Illnesses of siblings: Diabetes	0.4	0.5	1.8	0.8	0.3	0.2	0.0	0.2	1.1	0.9	0.6	0.7	0.1	0.2	0.2	0.3	0.2	1.1	1.4	0.6	1.0	0.4
Mood swings	0.4	0.6	1.3	0.9	0.7	0.8	1.0	1.1	0.9	0.1	0.9	0.5	1.1	0.3	0.9	0.8	0.9	-0.2	0.8	0.8	0.9	0.8
Illnesses of father: None of the above (group 1)	0.4	0.5	1.4	-0.5	-1.2	-0.9	-1.0	-1.2	-0.1	-0.3	-0.7	-0.3	-1.0	-0.1	-0.9	-0.8	-0.7	0.2	0.4	-0.2	-1.2	-0.6
Arm fat mass (left)	0.4	1.7	6.7	1.4	1.3	1.5	1.3	1.3	1.2	1.0	1.3	0.8	1.4	1.2	1.4	1.4	1.2	-0.2	0.9	0.7	2.6	1.2
Wears glasses or contact lenses	0.4	0.5	2.1	-0.4	-0.2	-0.1	-0.4	-0.5	-0.9	-1.2	-0.5	-0.6	-0.5	-0.2	-0.4	-0.4	-0.7	-0.7	-1.4	-1.0	0.3	-0.6
Ever depressed for a whole week	0.4	0.6	1.2	0.7	0.7	0.5	0.7	0.6	0.8	1.1	0.9	0.8	0.7	0.3	0.7	0.7	0.7	0.8	0.9	0.7	0.7	0.7
Verbal and Numeric Reasoning (VNR)	0.3	0.6	1.3	-0.7	-0.8	-0.7	-0.8	-1.1	-0.7	-1.2	-0.8	-0.5	-1.1	-0.6	-0.7	-0.8	-0.8	-0.5	-0.6	-0.7	-1.0	-0.6
Breast Cancer	0.3	0.8	1.9	-0.9	-0.8	-0.9	-0.9	-0.9	-0.8	-1.4	-0.8	-0.8	-1.1	-0.5	-1.0	-1.0	-1.0	-0.4	-0.7	-1.0	-0.3	-0.8
Ovarian Cancer	0.3	0.4	2.3	-0.7	-0.4	-0.2	0.0	-0.0	-1.1	-0.7	-0.6	-0.8	-0.0	-0.2	-0.2	-0.2	-0.5	-1.1	-1.5	-1.0	0.2	-0.6
Crohns Disease (2012)	0.3	0.4	2.6	0.2	0.1	-0.0	0.2	0.0	0.6	1.4	0.3	0.6	-0.0	0.7	-0.0	0.0	0.1	1.6	0.9	0.8	-0.3	0.4
Rheumatoid Arthritis	0.3	0.4	0.9	0.5	0.7	0.7	0.7	0.6	0.4	-0.2	1.0	0.6	0.7	0.0	0.7	0.7	0.6	0.5	0.2	0.5	0.9	0.7
Respiratory disease	0.3	0.8	5.8	-0.3	0.4	0.2	0.3	0.2	-0.9	-0.2	-0.2	-1.1	0.3	-0.2	0.1	-0.1	-0.3	-2.4	-1.6	-1.3	1.2	-0.5
Lung FVC	0.3	1.6	2.3	-1.2	-1.4	-1.3	-1.5	-1.4	-1.0	-1.2	-1.2	-1.4	-1.4	-0.9	-1.3	-1.3	-1.2	-1.3	-0.8	-1.1	-1.5	-1.3
Sensitivity / hurt feelings	0.3	0.5	3.2	0.5	1.0	0.9	0.6	0.8	-0.0	-0.3	0.1	-0.4	0.7	0.5	0.7	0.5	0.4	-1.8	-0.7	-0.4	1.2	0.1
Relative age of first facial hair	0.3	0.7	1.6	-0.8	-0.7	-1.0	-1.1	-1.3	-0.5	0.7	-0.8	-0.6	-1.0	-0.6	-0.9	-0.9	-0.8	-0.2	-0.2	-0.5	-1.1	-0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.0	0.6	0.8	0.5	0.5	0.3	0.6	1.0	0.5	0.6	0.4	0.3	0.4	0.5	0.3	0.5	0.6	0.5	0.9	0.5
Medication for hormone replacement therapy	0.3	0.4	2.3	0.3	0.1	0.3	0.7	0.7	0.4	0.5	0.5	0.5	0.7	0.6	0.4	0.5	0.4	0.6	0.6	0.4	1.5	0.5
Maternal smoking around birth	0.3	0.4	2.0	-0.7	-0.6	-0.3	-0.2	-0.2	-1.0	-1.4	-0.6	-0.6	-0.1	-0.2	-0.3	-0.4	-0.3	-0.6	-1.1	-0.5	-1.1	-0.5
Fed-up feelings	0.3	0.5	1.4	0.7	0.9	0.9	1.0	1.2	0.3	0.7	0.5	0.4	1.1	-0.0	0.8	0.8	0.7	0.1	-0.2	0.3	0.9	0.5
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.2	0.6	0.8	0.8	0.9	0.8	0.1	0.8	0.3	0.3	0.7	1.1	0.7	0.6	0.6	-0.1	-0.5	0.2	-0.0	0.3
Financial difficulties in last 2 years	0.3	0.4	0.6	-0.5	-0.6	-0.6	-0.5	-0.6	-0.6	0.1	-0.6	-0.7	-0.5	-0.4	-0.6	-0.6	-0.6	-0.6	-0.7	-0.7	-0.7	-0.8
Medication: Simvastatin	0.3	0.5	0.9	-0.7	-0.5	-0.7	-0.9	-0.9	-0.6	-0.8	-0.4	-0.4	-0.8	-0.9	-0.8	-0.7	-0.8	-0.1	-0.5	-0.7	0.4	-0.6
Fluid intelligence score	0.3	0.7	1.3	-0.7	-0.8	-0.8	-1.0	-1.1	-0.5	-1.2	-0.8	-0.5	-1.1	-0.7	-0.9	-0.9	-0.9	-0.2	-0.3	-0.5	-1.1	-0.7
Depression (self-reported)	0.3	0.3	1.4	-0.2	-0.0	-0.3	-0.8	-0.7	-0.3	-0.3	-0.5	-0.4	-0.7	0.5	-0.5	-0.6	-0.5	-0.3	-0.5	-0.4	-1.2	-0.5
Birth weight of first child	0.3	0.5	2.1	0.1	0.3	0.5	0.5	0.6	-0.5	-1.0	0.2	-0.4	0.7	1.5	0.6	0.5	0.4	-1.3	-1.2	-0.4	-0.1	-0.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.1	0.7	0.6	0.6	0.7	0.6	0.9	0.6	0.8	0.7	0.7	-0.3	0.9	0.8	0.9	0.3	1.1	1.0	0.4	0.9
Wheeze or whistling in the chest in last year	0.3	0.5	1.5	0.6	0.2	0.4	0.5	0.6	0.7	1.2	0.8	0.6	0.5	0.9	0.5	0.5	0.6	0.8	0.9	0.8	-0.2	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.8	0.3	-0.2	0.1	0.2	0.2	0.6	0.7	0.4	0.7	0.1	0.9	0.1	0.2	0.2	1.3	0.8	0.8	-0.1	0.5
Chest pain or discomfort	0.3	0.5	1.2	-0.6	-0.7	-0.9	-0.9	-1.1	-0.3	-0.3	-0.5	-0.6	-1.0	-0.4	-0.9	-0.9	-0.9	-0.2	-0.0	-0.6	-0.2	-0.7
Illnesses of father: Heart disease	0.3	0.4	1.6	0.4	1.3	0.8	0.8	0.9	-0.2	-0.1	0.5	0.3	0.8	0.3	0.7	0.7	0.5	0.1	-0.8	0.0	0.9	0.5
Loneliness, isolation	0.3	0.5	2.4	0.6	0.8	0.8	0.9	0.9	0.3	0.4	0.5	0.5	0.8	-0.1	0.7	0.7	0.5	0.1	-0.1	0.2	1.5	0.6
Ever had bowel cancer screening	0.3	0.4	0.9	0.5	1.0	0.7	0.7	0.6	0.2	-0.2	0.6	0.7	0.8	0.3	0.6	0.7	0.5	0.7	-0.1	0.4	0.8	0.5
Commuting to job workplace: Walk	0.3	0.4	1.8	0.5	0.5	0.5	0.7	0.8	0.5	1.3	0.3	0.5	0.7	0.4	0.5	0.6	0.6	0.5	0.3	0.6	0.1	0.5
Eye problems/disorders: Cataract	0.3	0.4	1.2	0.7	0.5	0.4	0.1	0.2	0.9	0.6	0.6	0.6	0.3	0.6	0.4	0.4	0.5	0.6	1.1	0.7	0.7	0.6
Medication: Aspirin	0.3	0.4	2.0	-0.3	-0.0	-0.4	-0.6	-0.5	-0.3	-0.9	-0.4	0.3	-0.4	-0.9	-0.4	-0.3	-0.3	1.4	-0.2	0.1	-1.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.6	-0.7	-0.8	-0.7	-1.0	-0.9	-0.7	-1.0	-0.9	-0.7	-0.8	-0.4	-0.8	-0.8	-0.8	-0.3	-0.7	-0.6	-1.3	-0.8
Financial situation satisfaction	0.3	0.4	1.5	-0.5	-0.5	-0.6	-0.4	-0.5	-0.5	0.1	-0.5	-0.9	-0.4	-0.8	-0.5	-0.5	-0.5	-1.2	-0.5	-0.6	-1.0	-0.9
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.8	0.6	0.7	0.5	0.1	0.0	0.6	-0.2	0.4	0.7	0.2	1.0	0.3	0.4	0.2	0.9	0.6	0.3	1.4	0.5
Number of operations (self-reported)	0.3	0.4	0.9	0.8	0.6	0.6	0.6	0.3	0.8	0.9	0.9	0.6	0.6	0.4	0.7	0.7	0.8	0.1	0.9	0.7	0.6	0.6
Pain experienced in last month	0.3	0.4	1.9	0.6	0.7	0.5	0.3	0.2	0.7	0.2	0.7	1.0	0.2	0.2	0.4	0.5	0.5	1.4	0.8	0.7	0.3	0.8
Basal cell carcinoma (self-reported)	0.3	0.4	0.7	0.6	0.2	0.4	0.7	0.7	0.7	0.4	0.7	0.7	0.7	0.1	0.6	0.6	0.7	0.8	0.8	0.8	0.0	0.5
Alcohol drinker status: Previous	0.3	0.4	0.8	-0.8	-0.9	-0.8	-0.7	-0.7	-0.5	-0.3	-0.5	-0.2	-0.6	-0.8	-0.7	-0.7	-0.7	0.5	-0.2	-0.3	-0.7	-0.5
Depressed Affect (Nagel 2018)	0.2	0.4	2.2	0.6	0.4	0.6	0.8	0.8	0.6	0.1	0.7	0.3	0.8	0.4	0.6	0.6	0.6	-0.3	0.6	0.3	1.5	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.1	-0.9	-0.7	-0.8	-1.0	-1.0	-0.8	-0.4	-1.0	-0.5	-1.1	-1.4	-0.9	-0.9	-0.9	0.0	-0.8	-0.7	-0.9	-0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	1.1	0.5	0.4	0.3	0.3	0.5	0.6	0.7	0.3	0.4	0.6	0.2	0.4	0.5	0.6	0.0	0.6	0.7	-1.0	0.3
Ulcerative Colitis (UC)	0.2	0.3	0.8	-0.3	-0.9	-0.6	-0.4	-0.5	-0.1	-0.2	-0.4	-0.7	-0.5	0.9	-0.5	-0.5	-0.4	-0.9	0.1	-0.3	-0.8	-0.6
Bipolar Disorder (2011)	0.2	0.2	1.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.9	-0.9	-1.0	0.0	-0.8	-1.0	0.1	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	0.8	0.5	0.5	0.5	0.4	0.3	0.4	0.5	0.3	0.7	0.4	0.5	0.5	0.6	0.6	0.9	0.8	0.8	0.0	0.6
Fasting Glucose	0.2	0.2	0.5	-0.3	-0.1	-0.3	-0.4	-0.5	-0.4	-0.6	-0.3	-0.5	-0.6	-0.3	-0.5	-0.4	-0.6	-0.6	-0.5	-0.7	0.6	-0.4
Blood White Count	0.2	1.4	9.0	0.9	-0.3	0.1	-0.1	0.1	1.9	1.1	1.0	1.2	0.0	0.2	0.4	0.5	0.7	1.9	3.0	1.6	0.8	1.0
Waist Hip Ratio (WHR)	0.2	0.9	2.3	1.0	1.4	1.3	1.1	1.1	0.5	0.4	0.9	0.6	1.1	1.5	1.1	1.0	0.9	0.0	-0.2	0.5	0.8	0.8
Hand grip strength (left)	0.2	0.4	1.9	-0.4	-0.7	-0.6	-0.8	-0.7	0.0	-1.4	-0.3	-0.0	-0.7	-0.8	-0.7	-0.6	-0.5	0.8	0.5	0.0	-0.8	-0.3
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	-0.3	-0.1	-0.1	-0.3	-0.4	-0.7	-0.1	-0.3	-0.7	-0.2	-0.5	-0.3	-0.3	-0.4	-0.9	-1.1	-0.7	-0.5	-0.5
Supplements: Zinc	0.2	0.2	2.4	-0.0	0.2	0.3	0.3	0.2	-0.1	-0.1	0.5	-0.6	0.4	0.1	0.3	0.2	0.3	-1.6	-0.2	-0.3	0.5	-0.0
Diabetes (father)	0.2	0.3	0.5	-0.5	-0.5	-0.7	-0.7	-0.7	-0.3	0.0	-0.6	-0.4	-0.6	-0.7	-0.7	-0.6	-0.6	-0.4	-0.0	-0.5	-0.3	-0.6
Taking other prescription medications	0.2	0.3	0.8	-0.5	-0.4	-0.5	-0.3	-0.3	-0.5	-0.1	-0.3	-0.6	-0.4	-0.5	-0.4	-0.5	-0.4	-0.9	-0.5	-0.5	-0.9	-0.5
Serious illness, injury or assault to yourself	0.2	0.3	0.9	-0.4	-0.2	-0.4	-0.5	-0.6	-0.5	-0.3	-0.8	-0.4	-0.6	0.0	-0.5	-0.5	-0.5	-0.0	-0.5	-0.4	-0.9	-0.5
Stomach or abdominal pain in last month	0.2	0.2	1.4	-0.1	-0.6	-0.2	0.2	0.4	0.3	1.2	0.0	0.3	0.4	-0.6	0.1	0.1	0.3	0.7	0.7	0.6	-0.6	0.2
Past tobacco smoking	0.2	0.4	1.0	-0.3	-0.1	-0.2	-0.6	-0.5	-0.5	-1.0	-0.8	-0.6	-0.5	-0.9	-0.4	-0.5	-0.5	-0.6	-0.8	-0.6	-0.8	-0.4
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	1.6	-0.4	-0.1	-0.2	-0.3	-0.2	-0.5	-0.6	-0.3	-0.8	-0.3	-0.0	-0.3	-0.4	-0.3	-1.3	-0.6	-0.7	-0.2	-0.3
Neuroticism score	0.2	0.4	1.9	0.5	0.9	0.7	0.9	1.1	0.3	0.2	0.5	0.2	0.9	0.4	0.6	0.6	0.5	-0.7	0.0	0.1	1.4	0.4
Time employed in main current job	0.2	0.2	0.9	0.4	0.0	0.2	0.4	0.4	0.5	-0.1	0.3	0.1	0.3	1.0	0.2	0.2	0.2	-0.1	0.7	0.3	0.8	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.1	0.6	0.7	0.5	0.4	0.4	0.6	0.4	0.5	0.7	0.5	0.5	0.4	0.5	0.5	1.1	0.4	0.6	0.3	0.5
Happiness	0.2	0.2	0.8	0.2	0.7	0.4	0.4	0.4	-0.2	0.3	0.2	-0.4	0.4	0.8	0.3	0.3	0.2	-0.9	-0.8	-0.4	0.4	-0.1
Mouth/teeth dental problems: Dentures	0.2	0.4	2.4	0.4	0.5	0.6	0.5	0.7	0.1	0.7	0.6	0.3	0.5	0.8	0.6	0.5	0.4	-0.2	-0.1	0.0	1.6	0.5
Lung cancer (father)	0.2	0.2	1.0	0.4	0.3	0.5	0.7	0.6	0.3	-0.0	0.6	0.1	0.6	0.4	0.6	0.5	0.5	-0.4	0.2	0.1	1.0	0.4
Exposure to tobacco smoke at home	0.2	0.2	0.7	-0.6	-0.8	-0.5	-0.4	-0.3	-0.6	-0.5	-0.6	-0.4	-0.3	-0.4	-0.3	-0.4	-0.3	-0.3	-0.5	-0.4	-0.5	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.0	0.8	0.9	0.6	0.3	0.4	0.8	0.5	1.0	0.4	0.4	0.9	0.5	0.5	0.5	-0.2	0.6	0.4	0.4	0.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	2.2	-0.5	-0.7	-0.1	0.1	0.1	-0.7	-0.4	-0.5	-0.9	0.0	-0.0	-0.1	-0.2	-0.1	-1.5	-0.9	-0.6	-0.6	-0.4
Birth weight	0.2	0.5	1.8	0.3	0.7	1.0	0.9	0.9	-0.5	-0.8	-0.0	-0.1	0.8	0.9	0.8	0.6	0.6	-1.1	-1.4	-0.3	0.5	0.3
Body fat percentage	0.2	0.9	2.5	1.0	0.7	0.9	0.8	0.8	1.0	1.3	1.0	0.7	0.9	1.2	1.0	0.9	0.9	0.2	1.0	0.8	1.6	1.0
Worry too long after embarrassment	0.2	0.3	2.2	-0.2	0.1	-0.1	0.0	0.2	-0.4	-0.6	-0.3	-0.5	0.1	-1.5	-0.0	-0.1	-0.1	-1.1	-0.6	-0.5	0.1	-0.4
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.7	-0.3	-0.2	-0.5	-0.8	-0.8	-0.3	0.2	-0.4	-0.3	-0.8	-0.4	-0.6	-0.6	-0.7	0.0	-0.2	-0.5	0.3	-0.5
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.7	0.3	0.1	0.1	0.2	0.0	0.6	0.4	0.3	0.6	0.1	0.2	0.2	0.2	0.3	0.8	0.9	0.7	-0.2	0.3
Medication: Aspirin	0.2	0.3	2.6	0.0	0.2	-0.1	-0.2	-0.1	0.1	-0.6	0.0	0.6	-0.0	-0.7	-0.1	0.0	0.0	1.6	0.2	0.5	-0.9	0.0
Knee pain experienced in last month	0.2	0.4	1.0	-0.6	-0.8	-0.6	-0.4	-0.3	-0.7	-0.7	-0.7	-0.7	-0.2	-0.2	-0.4	-0.4	-0.3	-0.8	-0.7	-0.5	-1.0	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.6	-0.8	-0.8	-0.6	-0.3	-0.2	-0.6	-0.2	-0.7	-0.3	-0.3	-0.2	-0.5	-0.4	-0.5	0.1	-0.4	-0.3	-0.3	-0.4
Medication: Gliclazide	0.2	0.2	0.6	-0.2	-0.3	-0.5	-0.6	-0.5	-0.0	-0.6	-0.3	-0.1	-0.5	-0.8	-0.5	-0.4	-0.4	0.7	0.2	-0.1	-0.4	-0.3
Commuting to job workplace: Public transport	0.2	0.3	0.9	-0.5	-0.6	-0.2	-0.5	-0.1	-0.7	-0.9	-0.4	-0.5	-0.4	-0.4	-0.4	-0.4	-0.6	-0.5	-0.9	-0.8	0.4	-0.3
Medication: Bendroflumethiazide	0.2	0.2	0.4	0.5	0.5	0.6	0.4	0.5	0.5	0.6	0.6	0.6	0.4	0.1	0.5	0.5	0.6	0.6	0.3	0.6	-0.3	0.5
Medication: Atorvastatin	0.2	0.3	1.3	-0.4	-0.2	-0.4	-0.3	-0.3	-0.3	0.8	-0.4	0.1	-0.5	-1.0	-0.4	-0.3	-0.3	0.8	-0.2	-0.0	-1.1	-0.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.2	-0.4	-0.2	-0.3	-0.1	-0.2	-0.4	-0.1	-0.0	-0.6	-0.0	-0.8	-0.2	-0.3	-0.2	-1.1	-0.4	-0.4	-0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	2.2	-0.3	0.1	-0.0	-0.1	-0.2	-0.6	-0.1	-0.4	-0.7	-0.2	-0.4	-0.2	-0.3	-0.4	-1.5	-1.0	-0.7	0.2	-0.4
Neuroticism (Nagel 2018)	0.1	0.3	1.3	0.5	0.5	0.6	0.6	0.8	0.3	-0.1	0.5	-0.1	0.7	0.3	0.6	0.6	0.6	-1.1	0.1	-0.0	1.0	0.3
Worry (Nagel 2018)	0.1	0.2	1.2	-0.4	-0.2	-0.3	-0.3	-0.2	-0.4	-0.4	-0.2	-0.6	-0.3	0.6	-0.3	-0.3	-0.4	-1.1	-0.5	-0.6	-0.0	-0.5
Alzheimer’s Disease (in father)	0.1	0.1	0.3	0.2	-0.2	0.0	-0.1	-0.1	0.4	0.5	-0.3	0.2	-0.3	0.4	-0.0	-0.1	0.0	0.2	0.5	0.2	-0.2	0.2
Age at First Birth	0.1	0.2	0.4	-0.5	-0.3	-0.5	-0.2	-0.4	-0.5	0.6	-0.3	-0.5	-0.6	-0.3	-0.3	-0.3	-0.3	-0.7	-0.6	-0.6	0.1	-0.4
Primary Biliary Cirrhosis	0.1	0.2	0.4	-0.3	0.0	-0.3	-0.5	-0.6	-0.4	-0.6	-0.3	-0.3	-0.5	0.0	-0.5	-0.4	-0.5	-0.1	-0.5	-0.5	-0.2	-0.5
Ulcerative Colitis	0.1	0.2	1.3	-0.2	-0.4	-0.4	-0.3	-0.1	-0.2	0.0	-0.6	-0.6	-0.3	1.0	-0.3	-0.3	-0.2	0.0	-0.2	-0.1	-1.1	-0.5
Blood Eosinophil Count	0.1	1.0	2.0	1.3	1.4	1.4	1.1	1.1	1.0	0.8	0.9	0.5	1.1	0.3	1.3	1.2	1.3	-0.3	0.6	0.8	0.7	1.0
Blood Red Count	0.1	0.5	2.7	-0.6	-1.4	-0.8	-0.5	-0.4	-0.3	-0.5	-0.7	-0.4	-0.6	-1.6	-0.5	-0.4	-0.2	0.3	0.1	-0.2	-1.4	-0.5
Smoking Status	0.1	0.2	1.0	0.1	-0.2	-0.2	-0.1	-0.0	0.4	1.0	0.3	0.2	-0.2	-0.0	-0.2	-0.1	-0.2	0.4	0.7	0.2	1.0	0.1
Hypothyroidism (self reported)	0.1	0.2	0.7	0.3	0.2	0.2	0.3	0.2	0.6	0.5	0.3	0.3	0.3	-0.1	0.4	0.3	0.5	0.1	0.8	0.6	-0.2	0.4
Neuroticism	0.1	0.2	1.4	0.2	0.4	0.3	0.4	0.5	0.0	0.2	0.3	-0.1	0.4	0.5	0.3	0.2	0.1	-0.6	-0.1	-0.2	1.2	0.1
Tanning	0.1	1.5	5.3	1.1	1.3	1.3	1.5	1.4	0.9	1.4	1.2	1.1	1.3	0.4	1.2	1.2	1.1	0.8	0.6	0.9	2.3	1.3
Diabetes (mother)	0.1	0.1	0.3	-0.2	-0.2	-0.2	-0.3	-0.2	-0.3	-0.4	-0.4	-0.3	-0.2	0.4	-0.2	-0.2	-0.2	-0.3	-0.5	-0.4	-0.3	-0.3
Hand grip strength (right)	0.1	0.3	1.4	0.0	-0.4	-0.4	-0.7	-0.7	0.5	-1.1	0.0	0.3	-0.6	-0.6	-0.4	-0.3	-0.2	1.2	0.9	0.4	-0.7	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.8	-0.1	0.1	-0.1	-0.1	-0.3	-0.3	-0.6	-0.3	-0.5	-0.2	-0.2	-0.2	-0.3	-0.3	-0.9	-0.5	-0.6	0.1	-0.3
Medication: Levothyroxine sodium	0.1	0.2	0.4	0.4	0.6	0.4	0.3	0.2	0.5	0.6	0.5	0.3	0.3	-0.4	0.5	0.4	0.5	-0.1	0.6	0.5	0.1	0.5
Body mass index (BMI)	0.1	0.5	0.9	-0.6	-1.0	-0.8	-0.9	-0.9	-0.5	-0.3	-0.7	-0.8	-0.9	-0.6	-0.8	-0.8	-0.9	-0.6	-0.3	-0.9	0.7	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.5	0.5	0.7	0.4	0.3	0.3	0.4	0.4	0.4	0.2	0.3	0.6	0.3	0.3	0.3	0.1	0.2	0.2	0.3	0.3
Had menopause	0.1	0.1	0.3	-0.3	-0.4	-0.2	0.2	0.3	-0.1	-0.6	-0.0	-0.2	0.0	0.2	0.1	0.0	0.0	-0.5	0.0	-0.1	0.4	-0.0
Alcohol intake versus 10 years previously	0.1	0.1	1.1	-0.3	-0.3	-0.2	0.0	-0.1	-0.3	0.2	-0.1	-0.2	0.1	1.1	-0.0	-0.1	0.0	-0.3	-0.1	0.1	-0.7	-0.2
Father’s age at death	0.1	0.2	1.1	0.1	-0.1	-0.3	-0.3	-0.5	0.4	1.0	-0.1	-0.2	-0.5	0.0	-0.3	-0.3	-0.3	0.1	0.7	-0.0	0.7	-0.1
Asthma	0.1	0.1	1.2	-0.0	0.0	0.2	0.1	-0.0	-0.1	-0.1	0.2	-0.3	-0.0	0.5	0.0	-0.1	-0.1	-0.8	-0.3	-0.4	1.1	0.1
Illnesses of mother	0.1	0.1	0.3	0.4	0.2	0.2	0.2	0.1	0.5	0.0	0.2	0.3	0.1	0.6	0.2	0.2	0.2	0.2	0.5	0.3	-0.2	0.2
Pulse wave Arterial Stiffness index	0.1	0.1	0.4	-0.5	-0.5	-0.5	-0.2	-0.2	-0.4	0.3	-0.3	-0.2	-0.4	0.6	-0.4	-0.3	-0.4	0.4	-0.3	-0.3	0.1	-0.3
Length of working week for main job	0.1	0.1	0.4	-0.2	-0.2	-0.2	-0.0	-0.2	-0.3	-0.6	-0.3	-0.1	-0.2	-0.0	-0.2	-0.2	-0.3	-0.1	-0.4	-0.3	-0.0	-0.2
Breastfed as a baby	0.1	0.1	0.3	-0.1	-0.4	-0.1	-0.2	-0.2	-0.2	-0.3	-0.0	-0.3	-0.3	-0.5	-0.2	-0.2	-0.3	-0.4	-0.2	-0.4	0.4	-0.3
Tense / ‘highly strung’	0.1	0.2	0.6	0.3	0.5	0.4	0.7	0.8	0.2	-0.0	0.6	0.3	0.7	0.8	0.5	0.5	0.4	0.0	0.1	0.3	0.4	0.4
Peak expiratory flow (PEF)	0.1	0.2	1.1	0.2	0.4	0.5	0.6	0.7	-0.1	-1.0	0.1	0.1	0.7	0.4	0.5	0.5	0.4	-0.3	-0.3	0.1	0.4	0.3
Leg fat percentage (right)	0.1	0.4	1.5	0.4	-0.1	0.1	0.0	0.0	0.8	1.1	0.4	0.5	0.0	0.9	0.2	0.2	0.3	0.8	1.2	0.6	0.8	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.6	0.4	0.8	0.5	-0.1	-0.0	-0.0	0.5	0.4	-0.1	-0.0	0.8	0.1	0.1	-0.1	-0.7	-0.6	-0.3	0.5	-0.1
Health satisfaction	0.1	0.1	1.0	0.2	0.2	0.1	-0.2	-0.3	0.1	0.5	-0.1	-0.5	-0.1	-0.1	-0.1	-0.2	-0.1	-1.0	-0.2	-0.3	-0.0	-0.3
Neck or shoulder pain in last month	0.1	0.1	0.5	0.4	0.7	0.4	0.4	0.3	0.1	0.6	0.4	-0.1	0.4	0.0	0.3	0.2	0.2	-0.7	-0.2	0.1	0.4	0.1
Medication: Blood pressure	0.1	0.2	1.8	0.4	0.4	0.1	-0.1	-0.1	0.6	0.5	0.4	0.7	-0.0	-0.0	0.0	0.2	0.1	1.4	0.8	0.6	0.2	0.3
Alcohol intake frequency.	0.1	0.1	0.4	-0.3	-0.4	-0.2	-0.5	-0.6	-0.4	-0.3	-0.3	-0.1	-0.5	0.3	-0.4	-0.4	-0.5	0.1	-0.4	-0.4	0.4	-0.2
Overall health rating	0.1	0.2	1.1	0.1	0.4	0.1	0.1	0.1	-0.1	0.7	0.1	-0.4	0.2	0.1	0.1	0.0	-0.1	-1.0	-0.3	-0.5	1.0	-0.2
Supplements: Vitamin C	0.1	0.1	1.0	-0.1	0.3	0.1	-0.2	-0.2	-0.5	0.1	-0.0	-0.5	-0.1	0.0	-0.0	-0.1	-0.1	-0.5	-1.0	-0.5	-0.4	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.3	0.2	0.4	0.3	0.3	0.2	-0.0	-0.5	0.2	-0.0	0.3	-0.2	0.3	0.3	0.2	-0.4	-0.3	-0.1	0.4	0.1
Back pain experienced in last month	0.1	0.1	0.5	-0.1	-0.2	-0.1	-0.2	-0.3	-0.2	-0.4	-0.4	-0.4	-0.1	0.5	-0.2	-0.2	-0.2	-0.7	-0.5	-0.4	-0.1	-0.3
Asthma (self-reported)	0.1	0.2	1.6	0.3	0.3	0.5	0.4	0.3	0.1	0.2	0.5	-0.0	0.3	0.7	0.3	0.3	0.2	-0.6	-0.0	-0.1	1.3	0.4
Number of self-reported non-cancer illnesses	0.1	0.2	1.1	0.1	-0.1	0.0	0.2	0.1	0.3	0.8	0.6	0.3	0.2	-0.1	0.2	0.2	0.2	0.2	0.5	0.2	1.0	0.2
Guilty feelings	0.1	0.1	1.3	-0.2	0.0	-0.0	0.2	0.2	-0.4	0.2	-0.4	-0.5	0.1	0.2	0.0	-0.0	-0.0	-1.2	-0.6	-0.4	-0.1	-0.2
Medication: Blood pressure	0.1	0.1	0.4	0.0	0.0	0.3	0.5	0.4	-0.0	0.4	0.5	0.2	0.5	0.1	0.4	0.4	0.3	0.1	-0.0	0.1	0.6	0.4
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	0.4	0.2	0.3	0.2	0.4	0.4	-0.0	0.3	0.4	0.4	-0.0	0.3	0.3	0.3	0.2	0.4	0.4	0.3	0.3
High cholesterol (Self-reported)	0.1	0.1	0.4	-0.3	-0.1	-0.5	-0.6	-0.6	-0.1	0.2	-0.1	-0.1	-0.6	-0.3	-0.5	-0.5	-0.5	0.2	0.1	-0.3	0.3	-0.3
Leg fat percentage (left)	0.1	0.2	0.9	0.2	-0.2	-0.2	-0.3	-0.4	0.6	0.8	0.3	0.2	-0.3	0.7	-0.1	-0.1	-0.1	0.5	0.9	0.3	0.6	0.1
Unable to work because of sickness or disability	0.1	0.2	1.4	-0.3	-0.6	-0.5	-0.3	-0.3	-0.2	-0.2	0.0	-0.1	-0.1	-0.5	-0.3	-0.3	-0.1	0.1	-0.1	0.0	-1.2	-0.3
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.8	-0.5	-0.5	-0.5	-0.4	-0.3	-0.6	-0.7	-0.7	-0.4	-0.4	-0.7	-0.5	-0.5	-0.5	-0.1	-0.5	-0.4	-0.9	-0.5
Cholesterol lowering medication	0.1	0.1	0.3	-0.5	-0.4	-0.1	-0.1	-0.1	-0.5	-0.1	0.0	-0.1	-0.2	-0.5	-0.1	-0.1	-0.1	-0.2	-0.5	-0.3	-0.1	-0.0
Pack years of smoking	0.1	0.1	0.8	0.1	0.1	0.2	0.3	0.4	-0.1	-0.0	0.4	0.1	0.3	-0.4	0.3	0.3	0.2	-0.3	-0.2	-0.1	0.9	0.2
Depression (Nagel 2018)	0.0	0.1	0.2	-0.1	-0.0	-0.1	-0.3	-0.4	-0.3	0.2	-0.2	-0.2	-0.3	-0.2	-0.3	-0.3	-0.4	-0.1	-0.5	-0.5	0.2	-0.3
Alzheimer’s Disease (including proxy)	0.0	0.1	0.3	0.4	-0.0	0.4	0.2	0.0	0.4	0.2	-0.1	0.1	-0.1	0.6	0.1	0.1	0.1	-0.1	0.3	0.1	0.5	0.4
Blood Platelet Count	0.0	0.3	1.2	-0.3	-1.1	-0.6	-0.6	-0.5	0.0	0.2	-0.2	-0.7	-0.7	-0.0	-0.4	-0.5	-0.2	-1.0	0.5	-0.2	-0.9	-0.4
BMI	0.0	0.2	1.7	0.4	0.1	-0.1	-0.4	-0.5	0.6	-0.2	0.1	0.3	-0.3	0.2	-0.3	-0.1	-0.2	0.9	0.8	0.1	1.3	0.1
Lung FEV1/FVC ratio	0.0	0.2	0.6	0.1	0.5	0.5	0.6	0.6	-0.2	0.8	0.1	0.3	0.6	0.7	0.4	0.4	0.4	0.4	-0.5	0.2	0.2	0.3
Pack years adult smoking proportion	0.0	0.0	0.3	-0.1	-0.2	0.0	0.1	0.2	-0.2	-0.2	0.2	-0.1	0.1	-0.4	0.1	0.1	0.0	-0.2	-0.3	-0.2	0.6	0.0
Average weekly fortified wine intake	0.0	0.0	0.1	0.1	-0.3	-0.0	-0.2	-0.2	0.2	0.2	0.0	0.1	-0.4	-0.1	-0.1	-0.1	-0.1	0.3	0.3	0.0	0.1	0.1
High blood pressure	0.0	0.1	0.7	0.0	-0.3	-0.2	-0.3	-0.4	0.3	0.5	0.1	0.1	-0.3	0.1	-0.1	-0.1	-0.1	0.3	0.6	0.0	0.8	0.0
Nervous feelings	0.0	0.0	0.1	-0.1	-0.0	-0.2	-0.1	0.3	0.0	-0.1	-0.1	-0.0	-0.1	0.2	-0.2	-0.1	-0.2	0.2	0.2	0.0	-0.2	-0.1
Arm fat percentage (right)	0.0	0.1	0.7	0.1	-0.1	0.1	0.1	0.1	-0.0	0.2	-0.0	-0.3	0.1	0.4	0.1	0.1	0.0	-0.8	-0.1	-0.3	0.8	-0.0
Noisy workplace	0.0	0.0	0.3	-0.1	0.1	-0.0	0.3	0.2	-0.1	0.1	0.1	-0.1	0.3	-0.0	0.2	0.2	0.1	-0.2	-0.1	-0.1	0.5	-0.0
Comparative body size at age 10	0.0	0.1	0.4	-0.2	-0.3	-0.2	-0.3	-0.3	-0.0	-0.5	-0.4	-0.2	-0.4	0.1	-0.3	-0.3	-0.3	-0.3	0.1	-0.3	0.6	-0.1
Number of full sisters	0.0	0.1	0.4	-0.1	-0.1	0.0	0.1	0.2	-0.1	0.2	0.4	0.1	0.4	0.2	0.2	0.2	0.2	0.0	-0.0	-0.0	0.6	0.1
Had major operations	0.0	0.0	0.3	0.2	-0.1	-0.1	-0.1	-0.3	0.3	0.3	0.4	0.2	-0.1	-0.2	-0.0	0.0	0.0	0.2	0.5	0.2	-0.0	-0.1
Hypertension (Self-reported)	0.0	0.1	0.5	0.2	-0.1	0.0	-0.1	-0.2	0.4	0.5	0.3	0.2	-0.1	0.2	0.0	0.1	0.1	0.4	0.6	0.2	0.7	0.2
Arm fat percentage (left)	0.0	0.2	0.9	-0.2	-0.4	-0.2	-0.3	-0.3	-0.2	0.1	-0.3	-0.5	-0.2	0.1	-0.2	-0.2	-0.3	-0.9	-0.2	-0.6	0.8	-0.3
Average weekly red wine intake	0.0	0.1	0.3	0.0	0.1	0.1	-0.3	-0.3	-0.0	-0.3	-0.3	0.0	-0.2	-0.6	-0.0	-0.1	-0.0	0.2	-0.1	0.1	-0.5	0.1
Medication for cholesterol	0.0	0.1	0.3	0.4	0.4	-0.0	-0.4	-0.3	0.4	0.0	-0.2	-0.1	-0.2	-0.0	-0.1	-0.1	-0.0	-0.2	0.3	0.1	-0.5	-0.2
Illnesses of father: High blood pressure	0.0	0.0	0.2	-0.1	-0.4	0.0	0.2	0.4	-0.1	0.0	-0.2	0.0	0.3	-0.2	0.1	0.1	0.1	0.1	0.0	0.1	0.2	0.1

Hub : Genes

B3GNT8

Models

Trait associations