[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr1:182,298,784-184,739,300

Best TWAS P=6.45e-10 · Best GWAS P=2.56e-11 conditioned to 0.0375

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TSEN15	0.23	0.18	lasso	9	0.18	4.7e-21	6.3	6.2	6.5e-10	0.90	0.01	0.99	TRUE
2	GTEx	Adipose Visceral Omentum	RP11-181K3.4	0.13	0.06	lasso	3	0.14	8.3e-08	5.0	5.5	3.3e-08	0.04	0.04	0.96	TRUE
4	GTEx	Brain Cerebellar Hemisphere	TSEN15	0.38	0.08	lasso	13	0.16	5.3e-05	6.3	6.0	2.0e-09	0.83	0.01	0.96	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	TSEN15	0.11	0.08	blup	52	0.10	6.7e-12	6.3	6.0	2.2e-09	0.78	0.01	0.99	FALSE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GLT25D2	0.05	0.01	enet	10	0.04	6.3e-05	3.0	-5.7	1.0e-08	-0.69	0.01	0.93	FALSE
7	METSIM	Adipose	TSEN15	0.06	0.02	enet	28	0.04	1.3e-06	6.3	5.7	1.4e-08	0.76	0.01	0.99	FALSE
5	GTEx	Esophagus Muscularis	RP11-181K3.4	0.05	0.09	lasso	1	0.07	3.9e-05	5.2	5.2	2.2e-07	0.03	0.04	0.95	FALSE
3	GTEx	Artery Tibial	RP11-181K3.4	0.07	0.07	lasso	15	0.05	1.1e-04	4.9	5.1	2.8e-07	0.06	0.06	0.93	FALSE
6	GTEx	Nerve Tibial	LAMC1	0.07	0.08	enet	30	0.05	1.1e-04	5.1	5.1	3.0e-07	0.07	0.03	0.96	FALSE