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Traits
:
Leg fat-free mass (right)
:
←
chr22:41,300,370-43,032,870
Best TWAS P=1.05e-08 · Best GWAS P=4.36e-12 conditioned to 4.22e-06
41.2M
41.4M
41.6M
41.8M
42M
42.2M
42.4M
42.6M
42.8M
43M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
WBP2NL
0.06
0.04
blup
140
0.03
9.6e-05
-4.9
5.7
1.0e-08
-0.53
0.58
0.24
TRUE
2
GTEx
Skin Sun Exposed Lower leg
CENPM
0.05
0.00
enet
8
0.02
1.5e-02
-5.0
5.6
2.5e-08
-0.53
0.07
0.43
FALSE
1
GTEx
Breast Mammary Tissue (Female)
DESI1
0.14
0.07
lasso
4
0.11
4.2e-04
-4.9
5.1
3.1e-07
-0.45
0.08
0.12
FALSE