[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr2:85,083,503-86,513,102

Best TWAS P=5.01e-10 · Best GWAS P=1.72e-09 conditioned to 0.0275

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	GGCX	0.04	0.02	blup	44	0.02	2.7e-03	5.1	6.2	5.0e-10	0.72	0.11	0.70	TRUE
11	GTEx	Skin Sun Exposed Lower leg	GGCX	0.15	0.11	lasso	3	0.18	7.9e-15	4.9	5.9	3.9e-09	0.69	0.42	0.58	FALSE
9	GTEx	Pancreas	VAMP5	0.29	0.09	enet	4	0.05	3.2e-03	5.3	-5.8	7.2e-09	-0.66	0.02	0.76	FALSE
2	GTEx	Artery Tibial	GGCX	0.29	0.22	enet	14	0.24	6.3e-19	4.8	5.7	1.6e-08	0.69	0.55	0.44	FALSE
13	GTEx	Thyroid	GGCX	0.30	0.17	enet	10	0.23	1.4e-17	4.9	5.7	1.6e-08	0.74	0.52	0.48	FALSE
8	GTEx	Nerve Tibial	GGCX	0.38	0.30	lasso	7	0.33	6.5e-24	4.8	5.6	1.7e-08	0.72	0.56	0.44	FALSE
7	GTEx	Muscle Skeletal	GGCX	0.10	0.04	enet	11	0.02	2.7e-03	4.8	5.6	1.9e-08	0.78	0.09	0.91	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	GGCX	0.13	0.04	enet	11	0.06	3.9e-04	4.9	5.5	3.5e-08	0.64	0.24	0.38	FALSE
6	GTEx	Esophagus Muscularis	GGCX	0.14	0.12	lasso	9	0.12	1.1e-07	4.8	5.5	5.0e-08	0.75	0.39	0.61	FALSE
12	GTEx	Testis	GGCX	0.38	0.36	enet	25	0.40	8.6e-19	4.9	5.5	5.1e-08	0.72	0.50	0.50	FALSE
3	GTEx	Brain Cerebellum	GGCX	0.54	0.30	lasso	10	0.34	6.0e-11	4.9	5.4	6.1e-08	0.75	0.58	0.42	FALSE
1	GTEx	Artery Aorta	GGCX	0.23	0.22	lasso	6	0.23	5.5e-13	4.8	5.4	7.8e-08	0.74	0.46	0.54	FALSE
4	GTEx	Colon Transverse	GGCX	0.26	0.28	lasso	3	0.28	1.4e-13	4.9	5.3	1.2e-07	0.73	0.50	0.50	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	VAMP8	0.06	0.01	enet	15	0.02	2.1e-02	5.1	5.3	1.4e-07	0.45	0.04	0.19	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	C2orf68	0.06	0.06	lasso	2	0.05	1.1e-03	5.3	-5.2	1.6e-07	-0.88	0.02	0.71	FALSE
14	GTEx	Whole Blood	GGCX	0.15	0.14	lasso	4	0.15	1.7e-13	4.9	5.2	1.9e-07	0.73	0.54	0.46	FALSE
15	YFS	Blood	VAMP8	0.15	0.15	enet	37	0.18	2.2e-55	5.0	-5.2	1.9e-07	-0.75	0.46	0.53	FALSE
5	GTEx	Esophagus Gastroesophageal Junction	GGCX	0.24	0.16	lasso	6	0.12	4.3e-05	4.9	5.2	2.5e-07	0.74	0.28	0.54	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	GGCX	0.03	0.03	enet	5	0.02	8.7e-03	4.9	5.2	2.5e-07	0.82	0.05	0.56	FALSE