Best TWAS P=2.08e-10 · Best GWAS P=2.2e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BCL2L11 | 0.04 | 0.04 | lasso | 2 | 0.03 | 2.0e-04 | 6.3 | -6.4 | 2.1e-10 | -1.00 | 0.01 | 0.99 | TRUE |
2 | GTEx | Adrenal Gland | BCL2L11 | 0.21 | 0.05 | enet | 9 | 0.12 | 3.1e-05 | 4.5 | -5.2 | 2.1e-07 | -0.79 | 0.06 | 0.85 | FALSE |
3 | The Cancer Genome Atlas | Colon Adenocarcinoma | BCL2L11 | 0.07 | 0.01 | blup | 71 | 0.06 | 2.0e-04 | -5.1 | -5.3 | 1.0e-07 | -0.85 | 0.02 | 0.94 | FALSE |