[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr3:55,969,663-58,283,722

Best TWAS P=3.04e-11 · Best GWAS P=7.52e-11 conditioned to 0.0129

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RP11-755B10.4 0.11 0.06 lasso 11 0.04 1.4e-02 5.5 -5.5 4.5e-08 -0.01 0.03 0.90 TRUE
2 GTEx Artery Tibial RP11-755B10.4 0.11 0.06 enet 13 0.04 2.1e-04 5.4 -5.2 2.1e-07 -0.06 0.02 0.97 FALSE
3 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -6.0 5.5 3.5e-08 -0.82 0.05 0.87 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -3.9 -5.4 7.7e-08 0.54 0.46 0.54 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -5.9 -6.6 3.9e-11 0.79 0.01 0.99 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -5.9 5.5 4.7e-08 -0.89 0.01 0.85 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC66 0.09 0.05 blup 56 0.06 5.3e-07 -5.0 -5.1 3.0e-07 0.69 0.44 0.56 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -5.9 -6.6 3.0e-11 0.73 0.01 0.99 TRUE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -4.7 -5.4 6.8e-08 0.51 0.34 0.26 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -3.9 -5.5 4.8e-08 0.55 0.10 0.33 FALSE