[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr4:105,373,669-107,092,169

Best TWAS P=4.3e-20 · Best GWAS P=4.5e-22 conditioned to 0.000822

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-9.5	-9.2	4.3e-20	0.88	0.02	0.97	TRUE
4	GTEx	Brain Cortex	PPA2	0.14	0.09	lasso	9	0.09	1.6e-03	-8.0	-8.1	5.4e-16	0.88	0.04	0.69	FALSE
7	GTEx	Esophagus Mucosa	PPA2	0.18	0.06	enet	14	0.12	2.5e-08	6.0	-7.5	6.9e-14	0.72	0.02	0.97	FALSE
11	GTEx	Ovary	PPA2	0.18	0.10	lasso	3	0.14	2.2e-04	-6.7	-7.5	8.5e-14	0.76	0.04	0.77	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	PPA2	0.04	0.02	blup	84	0.04	6.1e-05	-7.8	-7.1	1.2e-12	0.77	0.14	0.65	FALSE
5	GTEx	Cells Transformed fibroblasts	PPA2	0.11	0.03	lasso	3	0.01	6.5e-02	-6.6	-6.9	4.4e-12	0.67	0.36	0.22	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPA2	0.08	0.03	bslmm	429	0.04	2.2e-05	-6.1	-6.7	2.0e-11	0.66	0.04	0.95	FALSE
2	GTEx	Artery Aorta	PPA2	0.11	-0.01	enet	24	0.01	1.6e-01	-9.5	-6.5	6.5e-11	0.63	0.04	0.63	FALSE
12	GTEx	Skin Sun Exposed Lower leg	TET2	0.09	0.01	enet	18	0.02	3.6e-03	-9.6	-6.5	6.9e-11	0.69	0.01	0.93	FALSE
10	GTEx	Nerve Tibial	PPA2	0.13	0.07	enet	23	0.07	2.1e-05	-6.7	-6.3	3.8e-10	0.66	0.35	0.47	FALSE
8	GTEx	Heart Atrial Appendage	PPA2	0.15	0.05	lasso	7	0.06	7.4e-04	-7.9	-6.1	8.9e-10	0.71	0.21	0.44	FALSE
3	GTEx	Brain Cerebellum	PPA2	0.22	0.01	lasso	4	0.03	3.7e-02	-6.7	-5.3	9.0e-08	0.62	0.09	0.16	FALSE
9	GTEx	Muscle Skeletal	PPA2	0.19	0.06	enet	28	0.11	8.7e-11	-7.8	-5.2	2.6e-07	0.60	0.72	0.28	FALSE