[Hub]/) : Traits : Leg fat-free mass (right) : ← →

chr1:35,908,451-37,494,602

Best TWAS P=2.15e-11 · Best GWAS P=9.97e-12 conditioned to 0.229

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Artery Aorta	RP11-268J15.5	0.20	0.14	lasso	4	0.13	1.2e-07	-6.4	-6.7	2.2e-11	0.31	0.02	0.97	TRUE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	TRAPPC3	0.07	0.02	blup	38	0.03	5.7e-03	-5.1	-5.7	1.1e-08	0.69	0.05	0.40	TRUE
19	The Cancer Genome Atlas	Colon Adenocarcinoma	MAP7D1	0.06	0.01	blup	33	0.04	1.3e-03	-5.9	-6.5	7.4e-11	0.75	0.02	0.45	FALSE
5	GTEx	Lung	SH3D21	0.12	0.02	lasso	1	0.03	2.1e-03	-6.4	6.4	1.2e-10	-0.29	0.02	0.96	FALSE
7	GTEx	Skin Sun Exposed Lower leg	SH3D21	0.15	0.07	lasso	5	0.08	4.7e-07	6.1	6.4	1.4e-10	-0.37	0.06	0.92	FALSE
13	METSIM	Adipose	SH3D21	0.05	0.05	lasso	3	0.04	5.1e-07	-6.4	6.4	1.5e-10	-0.29	0.02	0.98	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	SH3D21	0.28	0.18	lasso	5	0.19	4.1e-24	-6.4	6.3	2.6e-10	-0.28	0.01	0.99	FALSE
9	GTEx	Thyroid	RP11-268J15.5	0.13	0.12	lasso	4	0.10	2.7e-08	-6.4	-6.3	3.2e-10	0.29	0.02	0.98	FALSE
4	GTEx	Lung	RP11-268J15.5	0.27	0.16	lasso	4	0.15	1.6e-11	-6.4	-6.2	4.6e-10	0.28	0.02	0.98	FALSE
1	GTEx	Adipose Visceral Omentum	RP11-268J15.5	0.17	0.14	lasso	2	0.11	2.8e-06	-6.4	-6.2	7.9e-10	0.25	0.02	0.97	FALSE
3	GTEx	Artery Tibial	RP11-268J15.5	0.11	0.10	lasso	3	0.08	4.1e-07	-6.4	-6.0	1.5e-09	0.29	0.03	0.97	FALSE
12	METSIM	Adipose	RP11-268J15.5	0.05	0.06	lasso	3	0.05	4.0e-08	-6.4	-6.0	2.2e-09	0.29	0.02	0.98	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	RP11-268J15.5	0.21	0.16	lasso	5	0.17	4.3e-21	-6.4	-5.9	3.7e-09	0.21	0.01	0.99	FALSE
6	GTEx	Nerve Tibial	RP11-268J15.5	0.18	0.09	lasso	5	0.08	1.5e-06	-6.4	-5.8	5.0e-09	0.25	0.02	0.98	FALSE
10	GTEx	Thyroid	SH3D21	0.14	0.03	lasso	4	0.05	6.6e-05	-6.4	5.8	7.4e-09	-0.27	0.02	0.96	FALSE
11	GTEx	Whole Blood	MAP7D1	0.12	0.09	lasso	3	0.09	8.3e-09	-5.6	-5.7	1.2e-08	0.78	0.76	0.24	FALSE
17	YFS	Blood	MAP7D1	0.04	0.03	lasso	7	0.03	8.3e-10	-5.5	-5.7	1.6e-08	0.78	0.80	0.20	FALSE
8	GTEx	Thyroid	TRAPPC3	0.10	0.08	lasso	3	0.08	7.2e-07	-5.5	5.6	1.8e-08	-0.76	0.30	0.66	FALSE
18	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM176B	0.14	0.04	blup	23	0.04	1.8e-03	-6.4	5.6	2.2e-08	-0.34	0.00	0.97	FALSE
14	NTR	Blood	MAP7D1	0.02	0.03	lasso	3	0.02	3.4e-08	-5.5	-5.5	3.4e-08	0.76	0.28	0.72	FALSE