[Hub]/) : Traits : Leg fat-free mass (right) :

chr1:35,908,451-37,494,602

Best TWAS P=2.15e-11 · Best GWAS P=9.97e-12 conditioned to 0.229

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-268J15.5 0.17 0.14 lasso 2 0.11 2.8e-06 -6.4 -6.2 7.9e-10 0.25 0.02 0.97 FALSE
2 GTEx Artery Aorta RP11-268J15.5 0.20 0.14 lasso 4 0.13 1.2e-07 -6.4 -6.7 2.2e-11 0.31 0.02 0.97 TRUE
3 GTEx Artery Tibial RP11-268J15.5 0.11 0.10 lasso 3 0.08 4.1e-07 -6.4 -6.0 1.5e-09 0.29 0.03 0.97 FALSE
4 GTEx Lung RP11-268J15.5 0.27 0.16 lasso 4 0.15 1.6e-11 -6.4 -6.2 4.6e-10 0.28 0.02 0.98 FALSE
5 GTEx Lung SH3D21 0.12 0.02 lasso 1 0.03 2.1e-03 -6.4 6.4 1.2e-10 -0.29 0.02 0.96 FALSE
6 GTEx Nerve Tibial RP11-268J15.5 0.18 0.09 lasso 5 0.08 1.5e-06 -6.4 -5.8 5.0e-09 0.25 0.02 0.98 FALSE
7 GTEx Skin Sun Exposed Lower leg SH3D21 0.15 0.07 lasso 5 0.08 4.7e-07 6.1 6.4 1.4e-10 -0.37 0.06 0.92 FALSE
8 GTEx Thyroid TRAPPC3 0.10 0.08 lasso 3 0.08 7.2e-07 -5.5 5.6 1.8e-08 -0.76 0.30 0.66 FALSE
9 GTEx Thyroid RP11-268J15.5 0.13 0.12 lasso 4 0.10 2.7e-08 -6.4 -6.3 3.2e-10 0.29 0.02 0.98 FALSE
10 GTEx Thyroid SH3D21 0.14 0.03 lasso 4 0.05 6.6e-05 -6.4 5.8 7.4e-09 -0.27 0.02 0.96 FALSE
11 GTEx Whole Blood MAP7D1 0.12 0.09 lasso 3 0.09 8.3e-09 -5.6 -5.7 1.2e-08 0.78 0.76 0.24 FALSE
12 METSIM Adipose RP11-268J15.5 0.05 0.06 lasso 3 0.05 4.0e-08 -6.4 -6.0 2.2e-09 0.29 0.02 0.98 FALSE
13 METSIM Adipose SH3D21 0.05 0.05 lasso 3 0.04 5.1e-07 -6.4 6.4 1.5e-10 -0.29 0.02 0.98 FALSE
14 NTR Blood MAP7D1 0.02 0.03 lasso 3 0.02 3.4e-08 -5.5 -5.5 3.4e-08 0.76 0.28 0.72 FALSE
15 ROSMAP Brain Pre-frontal Cortex RP11-268J15.5 0.21 0.16 lasso 5 0.17 4.3e-21 -6.4 -5.9 3.7e-09 0.21 0.01 0.99 FALSE
16 ROSMAP Brain Pre-frontal Cortex SH3D21 0.28 0.18 lasso 5 0.19 4.1e-24 -6.4 6.3 2.6e-10 -0.28 0.01 0.99 FALSE
17 YFS Blood MAP7D1 0.04 0.03 lasso 7 0.03 8.3e-10 -5.5 -5.7 1.6e-08 0.78 0.80 0.20 FALSE
18 The Cancer Genome Atlas Colon Adenocarcinoma FAM176B 0.14 0.04 blup 23 0.04 1.8e-03 -6.4 5.6 2.2e-08 -0.34 0.00 0.97 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma MAP7D1 0.06 0.01 blup 33 0.04 1.3e-03 -5.9 -6.5 7.4e-11 0.75 0.02 0.45 FALSE
20 The Cancer Genome Atlas Colon Adenocarcinoma TRAPPC3 0.07 0.02 blup 38 0.03 5.7e-03 -5.1 -5.7 1.1e-08 0.69 0.05 0.40 TRUE