Best TWAS P=1.34e-13 · Best GWAS P=5.32e-15 conditioned to 0.00217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | CDKN2C | 0.14 | 0.11 | enet | 17 | 0.12 | 0.00003 | 7.7 | -7.4 | 1.3e-13 | -0.86 | 0.02 | 0.94 | TRUE |
2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 0.00126 | 5.2 | -5.2 | 1.5e-07 | 0.02 | 0.90 | 0.00 | TRUE |