Best TWAS P=1.45e-10 · Best GWAS P=1e-10 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | TEX10 | 0.10 | 0.09 | lasso | 4 | 0.10 | 3.1e-06 | 3.9 | 5.3 | 1.4e-07 | 0.92 | 0.02 | 0.98 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | TEX10 | 0.27 | 0.27 | lasso | 8 | 0.28 | 7.0e-23 | 6.5 | 6.4 | 1.4e-10 | 1.00 | 0.01 | 0.99 | TRUE |
3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | INVS | 0.10 | 0.03 | blup | 107 | 0.07 | 4.0e-04 | 6.2 | 5.2 | 1.6e-07 | 0.89 | 0.01 | 0.96 | FALSE |
4 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | INVS | 0.16 | 0.12 | enet | 8 | 0.08 | 2.8e-04 | 5.4 | 5.6 | 2.8e-08 | 0.77 | 0.24 | 0.65 | FALSE |