Best TWAS P=6.5e-11 · Best GWAS P=3.28e-10 conditioned to 0.00683
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | CTNNAL1 | 0.66 | 0.06 | enet | 84 | 0.18 | 2.8e-05 | -2.7 | 5.2 | 2.4e-07 | 0.46 | 0.12 | 0.44 | FALSE |
| 2 | NTR | Blood | C9orf5 | 0.05 | 0.02 | enet | 14 | 0.03 | 2.2e-10 | 3.9 | -6.2 | 7.5e-10 | -0.40 | 0.93 | 0.07 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C9orf4 | 0.08 | 0.03 | blup | 80 | 0.02 | 9.8e-04 | 3.9 | -5.2 | 1.9e-07 | -0.31 | 0.11 | 0.74 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTNNAL1 | 0.09 | 0.00 | blup | 83 | 0.04 | 1.0e-04 | 2.8 | 6.5 | 6.5e-11 | 0.44 | 0.04 | 0.14 | TRUE |