[Hub]/) : Traits : Leg predicted mass (right) :

chr10:76,465,803-80,383,574

Best TWAS P=6.08e-11 · Best GWAS P=1.28e-10 conditioned to 0.00353

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C10orf11 0.24 0.21 lasso 9 0.20 3.3e-16 5.9 -6.3 3.1e-10 0.03 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous DLG5 0.39 0.40 lasso 12 0.43 1.9e-38 -5.2 -5.1 3.0e-07 0.78 0.54 0.46 FALSE
3 GTEx Adipose Visceral Omentum C10orf11 0.40 0.32 enet 11 0.27 2.2e-14 5.9 -6.4 1.2e-10 0.02 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum DLG5 0.26 0.23 lasso 8 0.21 5.7e-11 -5.2 -5.1 2.7e-07 0.79 0.47 0.52 FALSE
5 GTEx Adrenal Gland C10orf11 0.24 0.22 enet 21 0.18 5.8e-07 5.9 -5.8 8.5e-09 0.02 0.01 0.99 FALSE
6 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 -5.2 -5.6 2.6e-08 0.74 0.29 0.52 FALSE
7 GTEx Artery Aorta DLG5 0.26 0.19 enet 10 0.22 2.6e-12 -5.0 -5.7 1.5e-08 0.82 0.36 0.64 TRUE
8 GTEx Artery Aorta RP13-39P12.3 0.14 0.13 enet 9 0.12 2.2e-07 -5.0 -5.5 3.1e-08 0.82 0.08 0.92 FALSE
9 GTEx Artery Coronary DLG5 0.33 0.25 lasso 4 0.27 1.4e-09 -5.4 -5.1 2.7e-07 0.80 0.24 0.75 FALSE
10 GTEx Artery Tibial DLG5 0.24 0.18 lasso 5 0.18 9.7e-14 -5.2 -5.2 2.4e-07 0.79 0.54 0.46 FALSE
11 GTEx Breast Mammary Tissue DLG5 0.15 0.09 lasso 7 0.08 6.7e-05 -5.1 -5.1 3.0e-07 0.79 0.24 0.51 FALSE
12 GTEx Cells Transformed fibroblasts DLG5 0.25 0.18 lasso 11 0.16 2.0e-12 -5.3 -5.5 4.1e-08 0.83 0.17 0.83 FALSE
13 GTEx Cells Transformed fibroblasts RP13-39P12.3 0.19 0.13 lasso 7 0.15 4.5e-11 -5.3 -5.2 2.1e-07 0.77 0.33 0.67 FALSE
14 GTEx Colon Transverse DLG5 0.23 0.17 lasso 8 0.19 1.4e-09 -5.4 -5.2 2.3e-07 0.80 0.44 0.56 FALSE
15 GTEx Esophagus Gastroesophageal Junction DLG5 0.27 0.03 enet 13 0.06 3.9e-03 -6.4 -5.2 2.1e-07 0.75 0.00 0.98 FALSE
16 GTEx Esophagus Muscularis C10orf11 0.45 0.39 enet 42 0.38 5.1e-24 5.9 -6.4 1.5e-10 0.01 0.02 0.98 FALSE
17 GTEx Heart Atrial Appendage DLG5 0.32 0.23 lasso 4 0.24 3.9e-11 -5.1 -5.2 1.7e-07 0.82 0.51 0.49 FALSE
18 GTEx Heart Left Ventricle DLG5 0.13 0.10 lasso 4 0.09 1.2e-05 -5.1 -5.1 2.7e-07 0.82 0.14 0.85 FALSE
19 GTEx Lung C10orf11 0.30 0.26 lasso 5 0.24 2.0e-18 5.9 -6.3 3.4e-10 0.03 0.01 0.99 FALSE
20 GTEx Lung DLG5 0.41 0.38 lasso 8 0.37 7.9e-30 -5.2 -5.3 1.5e-07 0.82 0.57 0.42 FALSE
21 GTEx Nerve Tibial DLG5 0.51 0.44 lasso 6 0.50 1.4e-39 -5.2 -5.6 2.4e-08 0.86 0.55 0.45 FALSE
22 GTEx Nerve Tibial RP13-39P12.3 0.31 0.25 lasso 7 0.36 1.3e-26 -5.2 -5.2 1.8e-07 0.80 0.26 0.74 FALSE
23 GTEx Ovary DLG5 0.62 0.38 lasso 6 0.40 5.3e-11 -5.3 -5.6 2.5e-08 0.76 0.50 0.49 FALSE
24 GTEx Ovary RP13-39P12.3 0.42 0.29 lasso 5 0.33 7.5e-09 -5.3 -5.5 4.8e-08 0.75 0.41 0.48 FALSE
25 GTEx Pancreas DLG5 0.39 0.43 enet 11 0.44 3.5e-20 -5.2 -5.2 2.1e-07 0.80 0.56 0.44 FALSE
26 GTEx Pancreas RP13-39P12.3 0.20 0.24 lasso 3 0.23 3.8e-10 -5.2 -5.2 2.2e-07 0.79 0.51 0.49 FALSE
27 GTEx Pituitary DLG5 0.45 0.36 lasso 11 0.31 1.9e-08 -5.3 -5.5 4.7e-08 0.83 0.06 0.93 FALSE
28 GTEx Pituitary RP13-39P12.3 0.38 0.22 lasso 11 0.17 3.8e-05 -5.3 -5.4 6.2e-08 0.83 0.03 0.93 FALSE
29 GTEx Skin Sun Exposed Lower leg DLG5 0.12 0.06 lasso 4 0.06 4.9e-06 -5.2 -5.2 2.0e-07 0.78 0.28 0.70 FALSE
30 GTEx Spleen DLG5 0.51 0.46 lasso 4 0.44 1.1e-12 -5.2 -5.2 1.6e-07 0.80 0.44 0.56 FALSE
31 GTEx Spleen RP13-39P12.3 0.38 0.34 lasso 2 0.35 8.8e-10 -5.2 -5.2 2.2e-07 0.76 0.30 0.68 FALSE
32 GTEx Stomach DLG5 0.20 0.12 lasso 7 0.08 1.3e-04 -5.2 -5.2 2.3e-07 0.79 0.32 0.60 FALSE
33 GTEx Thyroid C10orf11 0.38 0.21 lasso 9 0.25 6.7e-19 5.6 -6.5 6.1e-11 0.02 0.03 0.97 TRUE
34 GTEx Thyroid DLG5 0.39 0.43 lasso 5 0.43 1.5e-35 -5.2 -5.2 2.4e-07 0.79 0.59 0.41 FALSE
35 GTEx Thyroid RP13-39P12.3 0.28 0.30 lasso 8 0.29 3.3e-22 -5.2 -5.3 1.5e-07 0.79 0.57 0.43 FALSE
36 METSIM Adipose C10orf11 0.11 0.10 enet 14 0.10 1.1e-14 5.6 -5.7 1.2e-08 0.02 0.03 0.97 FALSE
37 ROSMAP Brain Pre-frontal Cortex ZNF503-AS2 0.07 0.06 lasso 2 0.06 2.2e-08 5.0 5.2 1.8e-07 0.02 0.58 0.41 FALSE
38 The Cancer Genome Atlas Prostate Adenocarcinoma DLG5 0.10 0.05 blup 116 0.05 2.1e-06 -5.2 -5.3 1.5e-07 0.66 0.56 0.44 FALSE