Best TWAS P=2.24e-07 · Best GWAS P=4.55e-08 conditioned to 0.078
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | VCL | 0.02 | 0.00 | blup | 57 | 0.01 | 0.00057 | 5.5 | -5.2 | 2.5e-07 | -0.82 | 0.00 | 0.90 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | VCL | 0.04 | 0.03 | lasso | 1 | 0.02 | 0.00058 | 5.2 | -5.2 | 2.2e-07 | -0.94 | 0.01 | 0.92 | TRUE |