[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr12:27,587,038-29,432,481

Best TWAS P=2.17e-09 · Best GWAS P=2.55e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts CCDC91 0.10 0.10 lasso 5 0.09 5.5e-07 -5.7 -5.8 6.7e-09 0.85 0.10 0.90 FALSE
2 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 -5.9 6.0 2.2e-09 -0.96 0.05 0.95 TRUE
3 GTEx Heart Atrial Appendage CCDC91 0.10 0.06 lasso 8 0.04 4.4e-03 -5.7 -5.1 2.9e-07 0.85 0.04 0.91 FALSE
4 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 -5.9 5.9 4.1e-09 -0.91 0.04 0.92 FALSE
5 GTEx Muscle Skeletal RP11-967K21.1 0.04 0.01 lasso 9 0.00 2.9e-01 -5.6 5.2 2.3e-07 -0.90 0.06 0.81 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 -6.3 -5.6 2.4e-08 0.87 0.03 0.97 FALSE
7 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 -5.9 -5.5 2.9e-08 0.85 0.07 0.88 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC91 0.04 0.04 lasso 3 0.03 1.8e-06 -5.4 -5.4 6.8e-08 0.94 0.17 0.83 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC91 0.09 0.11 lasso 2 0.12 2.3e-05 -5.5 -5.5 4.9e-08 0.91 0.07 0.91 FALSE