[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr12:109,231,851-113,517,494

Best TWAS P=1.6e-10 · Best GWAS P=1.18e-16 conditioned to 0.189

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	4.5	5.2	1.5e-07	-0.19	0.03	0.10	FALSE
2	GTEx	Artery Tibial	VPS29	0.05	0.03	lasso	3	0.02	5.9e-03	5.5	5.5	3.4e-08	-0.07	0.01	0.96	TRUE
3	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	-7.3	-6.4	1.6e-10	0.85	0.02	0.92	TRUE
4	GTEx	Brain Cerebellar Hemisphere	MMAB	0.31	0.27	lasso	3	0.24	6.6e-07	5.2	-5.2	1.8e-07	-0.06	0.02	0.98	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	MMAB	0.40	0.24	enet	16	0.28	2.5e-08	4.4	-5.2	1.6e-07	-0.01	0.06	0.84	FALSE
6	GTEx	Breast Mammary Tissue (Female)	VPS29	0.10	-0.01	lasso	2	0.02	1.0e-01	-3.9	5.3	1.2e-07	-0.24	0.02	0.33	FALSE
7	GTEx	Cells Transformed fibroblasts	VPS29	0.09	0.13	lasso	3	0.13	9.8e-10	5.5	5.1	2.9e-07	-0.03	0.00	1.00	FALSE
8	GTEx	Colon Sigmoid	KCTD10	0.25	0.16	lasso	8	0.15	6.2e-06	5.2	-5.4	7.0e-08	-0.03	0.07	0.91	FALSE
9	GTEx	Colon Transverse	MMAB	0.08	0.07	lasso	2	0.05	1.7e-03	5.2	-5.2	2.1e-07	-0.04	0.06	0.84	FALSE
10	GTEx	Muscle Skeletal	VPS29	0.06	0.06	lasso	3	0.05	4.3e-06	5.5	5.3	1.2e-07	-0.04	0.00	1.00	FALSE
11	GTEx	Thyroid	VPS29	0.07	0.01	lasso	5	0.01	8.9e-02	4.6	5.4	8.2e-08	-0.06	0.01	0.89	FALSE
12	NTR	Blood	ALDH2	0.06	0.01	blup	222	0.02	4.3e-08	4.4	6.1	8.7e-10	-0.60	0.38	0.62	TRUE
13	NTR	Blood	UBE3B	0.09	0.05	lasso	8	0.08	1.0e-25	4.9	5.7	1.3e-08	0.02	0.02	0.98	TRUE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	KCTD10	0.06	0.00	lasso	3	0.00	1.4e-01	4.9	-5.2	2.5e-07	-0.05	0.00	0.65	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MMAB	0.04	0.02	blup	53	0.02	5.2e-03	5.2	-5.3	1.5e-07	-0.05	0.01	0.62	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	CUX2	0.08	0.01	blup	95	0.02	1.3e-03	4.4	6.0	2.0e-09	-0.16	0.02	0.86	TRUE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	MMAB	0.06	0.06	blup	57	0.06	5.4e-07	-4.7	-5.6	2.1e-08	-0.03	0.08	0.91	FALSE