TWAS hub - ALDH2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0460	0.0170	3.1e-12	0.106	0.103	0.087	0.101	0.097	7.7e-13	1.8e-12	8.5e-11	2.6e-12	7.7e-12
2	GTEx	Artery Aorta	0.0520	0.0290	1.4e-03	0.041	NA	0.047	NA	0.039	2.5e-03	NA	1.3e-03	NA	3.0e-03
3	GTEx	Artery Tibial	0.0785	0.0409	2.9e-05	0.089	NA	0.062	NA	0.072	1.9e-07	NA	1.2e-05	NA	2.7e-06
4	GTEx	Brain Frontal Cortex BA9	0.3343	0.1162	5.4e-04	0.036	NA	0.092	NA	0.074	4.0e-02	NA	2.0e-03	NA	5.2e-03
5	GTEx	Brain Putamen basal ganglia	0.1190	0.0750	1.8e-03	0.000	NA	-0.003	NA	0.016	3.2e-01	NA	3.7e-01	NA	1.3e-01
6	GTEx	Esophagus Mucosa	0.0540	0.0270	1.6e-05	0.057	NA	0.063	NA	0.071	1.1e-04	NA	4.8e-05	NA	1.7e-05
7	GTEx	Heart Atrial Appendage	0.1590	0.0670	4.3e-04	0.140	NA	0.048	NA	0.103	7.7e-07	NA	3.3e-03	NA	2.4e-05
8	GTEx	Heart Left Ventricle	0.0986	0.0532	4.2e-04	0.054	NA	0.052	NA	0.046	7.6e-04	NA	9.6e-04	NA	1.7e-03
9	GTEx	Lung	0.0684	0.0367	1.3e-03	0.012	NA	0.018	NA	0.024	3.6e-02	NA	1.5e-02	NA	5.9e-03
10	GTEx	Nerve Tibial	0.0475	0.0255	7.9e-04	0.041	NA	0.031	NA	0.048	6.3e-04	NA	2.8e-03	NA	2.4e-04
11	GTEx	Skin Not Sun Exposed Suprapubic	0.1250	0.0500	5.1e-09	0.176	NA	0.143	NA	0.158	6.0e-10	NA	3.1e-08	NA	5.0e-09
12	GTEx	Skin Sun Exposed Lower leg	0.1030	0.0390	4.5e-10	0.088	NA	0.130	NA	0.128	8.9e-08	NA	6.7e-11	NA	9.4e-11
13	GTEx	Thyroid	0.0640	0.0340	2.3e-05	0.037	NA	0.048	NA	0.050	7.6e-04	NA	1.4e-04	NA	9.7e-05
14	METSIM	Adipose	0.0735	0.0406	8.8e-04	0.004	0.020	0.008	0.022	0.005	7.0e-02	4.0e-04	2.1e-02	2.5e-04	5.9e-02
15	NTR	Blood	0.0583	0.0196	2.6e-07	0.012	0.023	0.017	0.022	0.018	6.6e-05	4.3e-08	3.2e-06	1.1e-07	1.2e-06
16	YFS	Blood	0.3600	0.0648	0.0e+00	0.071	0.091	0.105	0.097	0.089	3.9e-22	2.4e-28	1.8e-32	6.3e-30	1.6e-27
17	TCGA	Colon Adenocarcinoma	0.0670	0.0470	5.5e-04	0.031	0.047	0.054	NA	0.055	6.1e-03	1.0e-03	4.8e-04	NA	3.9e-04
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.1036	0.0668	5.9e-03	-0.002	-0.001	0.001	NA	-0.002	9.6e-01	4.1e-01	2.6e-01	NA	6.9e-01
19	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1000	0.0620	4.2e-05	0.085	0.095	0.092	NA	0.075	1.5e-05	4.5e-06	6.3e-06	NA	4.6e-05
20	TCGA	Brain Lower Grade Glioma	0.0257	0.0234	4.7e-03	0.030	0.015	0.014	NA	0.028	2.2e-04	6.4e-03	8.0e-03	NA	3.1e-04
21	TCGA	Pheochromocytoma and Paraganglioma	0.0850	0.0500	3.0e-04	0.082	0.088	0.030	NA	0.046	3.7e-04	2.3e-04	2.3e-02	NA	6.6e-03
22	TCGA	Prostate Adenocarcinoma	0.0203	0.0151	6.8e-03	0.021	0.014	0.014	NA	0.014	2.7e-03	1.2e-02	1.2e-02	NA	1.3e-02
23	TCGA	Thyroid Carcinoma	0.0330	0.0270	2.7e-03	0.023	0.018	0.001	NA	0.011	2.6e-03	6.4e-03	2.7e-01	NA	2.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Blood Eosinophil Count	54.0	415.9	986.0	22.4	21.9	21.9	18.8	20.0	22.9	17.9	11.7	21.7	21.2	21.6	31.4	25.1	17.1	-17.6	-9.4	24.6	12.6	20.1	21.0	20.2	18.9	17.4
Medication: Levothyroxine sodium	32.5	55.1	127.7	8.3	7.3	8.1	6.8	7.7	8.3	5.9	4.1	7.8	7.8	8.0	11.3	8.8	6.8	-6.9	-3.5	8.5	4.9	6.9	7.7	7.6	7.1	6.8
Hypothyroidism (self reported)	30.8	70.8	196.0	8.6	8.4	8.7	9.4	7.8	9.1	7.2	3.6	8.5	8.1	8.3	14.0	9.9	8.5	-10.1	-5.2	10.9	5.7	6.9	8.0	7.7	6.8	6.5
Hypothyroidism/myxoedema (self-reported)	26.7	52.2	139.2	7.7	7.3	7.8	6.9	6.8	7.9	6.2	3.6	7.4	7.2	7.5	11.8	8.5	7.1	-7.8	-3.8	8.9	4.7	6.3	7.2	7.0	6.3	6.0
Blood White Count	26.2	194.5	449.4	16.1	13.7	15.2	12.3	14.2	15.9	10.2	8.8	14.1	14.6	15.2	21.2	18.1	9.9	-13.0	-8.5	16.1	9.6	12.6	14.5	14.2	13.1	12.5
Systolic Blood Pressure	15.2	76.3	153.8	10.4	8.3	9.4	9.3	11.1	9.5	5.8	5.8	9.0	9.1	9.7	12.2	12.4	4.8	-8.1	-3.7	8.3	5.2	8.0	9.0	8.7	8.5	8.2
Reaction Time	13.3	25.4	44.0	5.5	5.5	5.4	4.5	4.6	5.8	4.3	3.3	5.6	5.4	5.5	6.6	6.0	5.0	-3.5	-2.4	5.8	4.0	4.9	5.4	5.0	4.9	5.0
Diastolic blood pressure, automated reading	13.1	40.6	90.8	7.5	6.3	6.7	6.9	7.7	7.0	4.7	4.0	6.6	6.4	7.0	9.2	9.5	3.0	-6.0	-2.2	6.5	3.2	6.2	6.3	6.3	6.2	5.5
Mean time to correctly identify matches	11.9	22.6	43.5	5.5	5.0	5.3	3.9	4.2	5.4	3.8	2.9	5.1	5.1	5.4	6.6	5.7	4.7	-4.0	-2.2	5.4	3.5	4.5	5.0	4.7	4.6	4.7
High blood pressure	11.6	32.3	59.6	6.8	5.3	6.1	6.2	6.7	6.2	3.9	4.4	5.9	6.0	6.4	7.7	7.6	3.2	-4.3	-1.0	5.0	5.9	5.3	5.9	5.9	5.8	5.3
LDL Cholesterol	11.1	17.6	36.6	-4.6	-4.2	-4.7	-3.9	-3.5	-4.5	-3.6	-2.9	-4.3	-4.4	-4.8	-6.0	-4.4	-4.2	3.1	1.6	-4.7	-5.2	-3.8	-4.3	-3.9	-3.8	-4.1
Cardiovascular Disease	10.7	35.2	69.0	7.1	5.4	6.4	6.0	7.2	6.5	3.9	4.2	6.1	6.3	6.7	8.3	8.1	3.4	-4.3	-1.1	5.4	5.7	5.6	6.1	6.2	6.1	5.4
Blood Red Count	10.5	101.6	234.7	12.6	8.9	11.7	7.2	12.3	11.8	5.3	4.4	10.2	11.3	11.7	15.3	12.6	6.8	-9.1	-3.9	9.0	3.3	10.6	11.4	10.8	10.8	9.9
Qualifications: NVQ or HND or HNC or equivalent	9.9	12.0	18.5	-4.2	-3.7	-4.0	-0.9	-3.5	-3.7	-3.1	-3.4	-3.8	-4.0	-4.3	-3.5	-3.9	-2.8	-0.6	-0.9	-2.4	-1.9	-3.9	-4.0	-4.2	-4.3	-4.1
Medication: Blood pressure	9.5	18.1	32.0	4.8	4.2	4.6	5.5	4.6	4.5	3.3	3.1	4.5	4.2	4.7	5.7	5.3	3.4	-3.5	-1.9	4.4	4.5	3.3	4.0	4.3	3.9	3.9
Vascular/heart problems diagnosed by doctor	9.5	26.0	54.3	-6.2	-4.5	-5.5	-5.3	-6.0	-5.7	-2.9	-3.4	-5.1	-5.4	-5.7	-7.4	-7.0	-2.6	4.6	0.9	-4.5	-5.3	-4.7	-5.3	-5.2	-5.2	-4.5
Systolic blood pressure, automated reading	9.3	27.0	55.5	6.2	4.8	5.5	5.6	6.1	5.7	3.3	3.3	5.1	5.4	5.7	7.4	7.5	2.8	-5.7	-2.8	5.1	4.0	4.2	5.3	5.1	4.8	4.9
Hypertension (Self-reported)	9.2	25.5	48.8	6.2	4.5	5.4	5.5	6.2	5.4	3.2	3.6	5.1	5.3	5.7	7.0	6.9	2.6	-3.8	-0.4	4.2	5.3	4.7	5.2	5.3	5.2	4.6
Coronary Artery Disease (CAD)	9.0	10.7	22.6	3.5	2.8	3.3	3.7	3.3	3.8	1.7	1.2	3.2	3.2	3.1	4.7	3.6	2.9	-4.0	-2.5	3.8	4.6	2.6	3.7	2.6	2.4	2.7
Smoking status: Previous	8.7	13.0	30.5	4.2	3.1	4.2	1.4	2.5	4.6	2.1	2.0	3.5	4.2	4.2	5.5	3.9	3.2	-3.0	-1.9	4.2	3.1	3.7	4.2	4.0	3.8	3.5
Birth weight of first child	8.5	15.4	37.7	-4.5	-4.3	-4.4	-2.9	-4.1	-4.4	-3.4	-2.7	-4.1	-4.1	-4.3	-6.1	-4.8	-3.5	3.4	1.6	-4.4	-1.4	-3.6	-4.1	-3.9	-3.8	-3.6
Smoking status: Current	8.4	13.4	21.1	-3.6	-4.6	-4.0	-2.8	-2.4	-3.6	-4.4	-4.4	-4.5	-3.7	-4.0	-3.2	-3.3	-4.3	-0.9	-0.5	-3.7	-3.4	-3.7	-3.8	-4.2	-4.0	-4.0
Heart disease (mother)	8.2	10.0	18.7	3.7	3.0	3.8	0.9	2.0	3.8	2.3	3.1	3.4	3.7	3.8	4.3	2.7	3.2	-1.4	-0.7	3.4	2.3	3.2	3.6	3.8	3.5	3.8
Fed-up feelings	8.0	14.6	22.3	-4.2	-4.2	-4.2	-3.5	-3.2	-4.0	-4.0	-3.6	-4.2	-4.1	-4.4	-4.5	-4.7	-3.1	1.0	0.9	-4.1	-2.6	-3.7	-4.1	-4.3	-4.0	-4.2
Ever highly irritable/argumentative for 2 days	8.0	9.7	13.9	-3.6	-3.3	-3.5	-2.0	-2.9	-3.5	-2.6	-3.1	-3.6	-3.5	-3.6	-3.7	-3.4	-2.5	0.9	1.3	-3.0	-1.7	-3.0	-3.5	-3.7	-3.5	-3.7
Frequency of tiredness / lethargy in last 2 weeks	7.9	12.8	20.0	-3.5	-4.3	-3.9	-3.1	-2.3	-3.8	-4.2	-4.1	-4.2	-3.7	-3.8	-3.9	-3.6	-3.5	0.8	1.6	-4.5	-2.9	-3.1	-3.7	-3.9	-3.4	-3.9
Current tobacco smoking	7.8	12.7	19.9	-3.5	-4.5	-3.9	-2.5	-2.2	-3.4	-4.4	-4.2	-4.3	-3.6	-3.9	-2.9	-3.1	-4.4	-1.1	-0.5	-3.6	-3.5	-3.7	-3.7	-4.1	-3.9	-3.9
Medication: Atenolol	7.8	9.8	25.0	3.5	2.9	3.3	3.2	3.2	3.4	2.2	2.0	3.0	3.0	3.3	5.0	3.8	2.1	-4.0	-2.1	3.9	3.1	2.5	3.0	2.8	2.6	2.4
Primary Biliary Cirrhosis	7.4	10.5	24.5	3.7	3.2	3.6	3.1	3.4	3.6	2.1	1.9	3.1	3.3	3.6	4.9	3.8	2.3	-3.3	-1.3	3.4	3.8	3.0	3.5	3.0	3.0	2.8
Chronotype (morning person)	7.4	17.1	28.2	4.7	4.1	5.1	0.5	3.0	5.0	2.8	3.2	4.2	4.9	4.8	5.3	3.6	4.7	-2.7	-2.4	4.3	4.5	3.8	4.8	4.5	4.3	4.5
Pain experienced in last month	7.4	12.3	21.4	3.5	3.9	3.9	1.9	1.8	3.9	4.0	3.3	3.8	3.9	3.8	4.6	3.4	4.1	-1.1	-0.7	4.2	2.8	3.6	4.1	3.8	3.5	3.7
Birth weight	6.9	14.9	33.2	-4.7	-3.5	-4.4	-2.7	-5.3	-4.5	-2.1	-1.5	-3.9	-4.4	-4.4	-5.8	-4.6	-2.3	2.9	1.4	-3.6	-2.3	-4.3	-4.4	-4.0	-4.2	-3.5
Medication: Blood pressure	6.8	12.1	26.1	4.3	3.1	3.8	2.8	4.2	3.9	2.2	1.8	3.6	3.9	4.1	5.1	4.9	2.1	-2.4	0.4	3.0	2.0	3.9	3.9	3.7	3.8	3.2
Number of self-reported non-cancer illnesses	6.7	11.7	24.4	3.9	3.3	3.6	3.9	3.8	3.7	2.7	1.8	3.6	3.5	3.8	4.9	4.3	2.8	-2.7	-1.1	3.5	3.0	3.1	3.5	3.5	3.4	3.2
Loneliness, isolation	6.3	8.7	12.7	-3.4	-3.3	-3.4	-1.7	-2.8	-3.3	-2.6	-2.8	-3.4	-3.3	-3.4	-3.6	-3.4	-2.6	1.1	0.3	-2.8	-1.8	-2.9	-3.3	-3.4	-3.3	-3.3
Medication: Allopurinol	6.0	8.0	14.6	3.4	3.0	3.2	2.3	2.8	3.1	2.6	1.9	3.0	2.9	3.3	3.8	3.7	1.8	-1.2	-0.3	3.1	2.8	2.9	3.0	3.0	2.9	2.7
Frequency of unenthusiasm / disinterest in last 2 weeks	5.9	7.9	12.5	-3.5	-2.6	-3.2	-2.5	-3.5	-3.2	-1.7	-2.5	-3.1	-3.2	-3.3	-3.3	-3.4	-1.4	1.8	0.9	-2.4	-0.8	-2.9	-3.2	-3.2	-3.1	-3.3
Past tobacco smoking	5.7	10.4	26.4	-4.0	-2.5	-3.8	-0.6	-2.5	-4.2	-1.5	-1.3	-2.9	-3.8	-3.8	-5.1	-3.7	-2.2	2.8	1.9	-3.6	-2.3	-3.5	-3.8	-3.6	-3.5	-3.1
Headache pain in last month	5.6	9.6	21.2	-2.9	-3.3	-3.4	-2.5	-1.1	-3.3	-3.8	-2.9	-3.0	-3.1	-3.2	-4.3	-2.5	-3.3	2.5	3.0	-4.6	-3.0	-2.3	-3.2	-2.9	-2.4	-3.0
Medication for cholesterol	5.5	8.4	18.5	-3.1	-2.6	-3.0	-3.9	-3.1	-3.1	-1.8	-1.7	-2.9	-2.6	-2.9	-4.3	-3.6	-2.2	3.9	2.2	-3.3	-3.0	-1.8	-2.5	-2.6	-2.3	-2.3
Back pain experienced in last month	5.5	8.0	13.1	-3.3	-2.7	-3.2	-2.6	-3.6	-3.2	-1.7	-2.1	-3.0	-3.1	-3.1	-3.6	-3.6	-1.9	2.7	1.2	-2.5	-2.0	-2.5	-3.1	-3.0	-2.9	-3.0
Illnesses of siblings	5.4	7.6	20.3	-3.6	-2.2	-3.0	-3.3	-4.5	-3.0	-1.1	-0.9	-2.9	-3.0	-3.2	-3.8	-4.0	-0.8	2.5	0.2	-1.4	-0.3	-2.9	-2.9	-2.7	-3.1	-2.5
Gout (self-reported)	5.4	7.4	13.4	3.1	3.2	3.0	2.3	2.3	2.7	3.1	2.3	2.9	2.6	3.1	3.6	3.7	2.0	-0.8	-0.1	3.1	2.6	2.6	2.7	2.8	2.7	2.5
Taking other prescription medications	5.1	7.8	21.4	3.1	2.7	2.9	3.2	3.2	3.0	2.1	0.5	2.8	2.8	3.0	4.6	4.0	2.0	-3.1	-1.9	3.2	1.1	2.5	2.7	2.4	2.4	2.1
Illnesses of father: None of the above (group 1)	5.1	6.3	13.2	-3.2	-1.7	-2.7	-3.0	-3.2	-2.8	-1.1	-1.5	-2.2	-2.6	-2.9	-3.6	-3.4	-0.8	2.8	1.3	-2.0	-2.0	-2.2	-2.7	-2.5	-2.6	-2.5
Depression (Nagel 2018)	5.0	7.4	12.0	-3.4	-2.4	-3.3	-1.5	-2.9	-3.3	-1.4	-2.2	-2.8	-3.1	-3.2	-3.5	-2.9	-2.1	2.2	1.3	-2.4	-2.4	-2.6	-3.0	-3.1	-3.0	-3.1
Medication: Bendroflumethiazide	5.0	7.6	16.5	3.5	2.3	3.0	3.1	4.1	2.9	1.0	1.6	2.8	2.9	3.2	3.5	3.8	1.6	-2.2	-0.8	1.9	1.8	2.3	2.9	3.0	3.0	3.0
Number of full brothers	4.7	5.9	16.3	-2.0	-3.0	-2.5	-0.8	-0.4	-2.5	-2.9	-3.4	-2.6	-2.3	-2.3	-2.6	-1.6	-2.9	0.8	1.4	-3.6	-4.0	-2.0	-2.2	-2.4	-1.8	-2.3
Depressed Affect (Nagel 2018)	4.6	9.6	15.0	-3.7	-3.1	-3.7	-2.2	-2.4	-3.5	-2.8	-2.7	-3.2	-3.4	-3.7	-3.9	-3.8	-2.1	1.1	0.7	-3.2	-2.2	-3.3	-3.5	-3.6	-3.4	-3.3
Knee pain experienced in last month	4.5	7.0	13.3	-2.3	-3.5	-2.7	-1.5	-1.4	-2.7	-3.6	-2.8	-3.1	-2.8	-2.6	-2.6	-2.2	-3.5	-0.7	0.3	-3.3	-2.7	-2.8	-2.8	-2.8	-2.5	-2.6
Mood swings	4.5	8.1	13.0	-3.4	-2.9	-3.6	-0.7	-2.0	-3.3	-2.5	-2.4	-2.9	-3.3	-3.5	-3.6	-2.8	-2.5	0.6	0.6	-3.0	-1.1	-3.1	-3.4	-3.5	-3.3	-3.4
Number of treatments/medications taken	4.4	8.0	21.0	3.4	2.7	3.0	2.5	3.2	3.1	1.7	0.9	2.9	2.9	3.2	4.6	4.0	2.4	-3.1	-0.4	2.8	1.8	2.6	2.8	2.7	2.8	2.5
Blood Platelet Count	4.3	49.7	388.1	-2.6	-4.2	-2.1	6.4	2.1	-1.6	-4.7	-15.6	-4.2	-3.5	-3.9	11.9	-1.9	3.2	-19.7	-3.1	2.5	-5.3	-2.8	-3.6	-5.4	-5.6	-9.3
Father’s age at death	4.3	5.8	14.8	-2.3	-2.6	-2.3	-3.9	-2.1	-2.5	-2.7	-1.4	-2.5	-2.2	-2.3	-3.3	-3.3	-1.1	2.2	1.8	-3.3	-2.1	-2.4	-2.2	-1.9	-1.7	-1.5
High blood pressure (siblings)	4.3	6.1	13.2	3.0	2.3	2.7	2.7	3.6	2.7	1.5	1.6	2.8	2.7	2.7	3.5	3.2	1.6	-2.1	0.3	1.8	0.1	2.6	2.5	2.6	2.7	2.3
Ever smoked	4.1	7.2	17.1	3.1	2.3	3.0	0.5	2.2	3.6	1.5	1.3	2.6	3.2	3.1	4.1	3.0	1.9	-1.8	-1.6	3.1	1.9	3.0	3.2	3.0	2.9	2.6
Rheumatoid Arthritis	4.0	5.5	26.6	2.4	1.7	1.9	5.2	3.0	2.2	1.1	0.5	2.1	1.9	2.0	3.5	3.2	1.0	-4.2	-1.6	2.0	0.0	0.9	1.8	1.8	1.6	1.8
Hip circumference	3.9	16.9	38.0	-4.1	-4.7	-4.5	-3.0	-3.9	-4.4	-4.0	-3.0	-4.3	-4.1	-4.1	-6.2	-3.6	-4.7	4.1	2.8	-5.2	-3.5	-3.3	-4.1	-4.0	-3.5	-3.7
Blood clot in the leg (DVT)	3.9	5.1	11.1	2.5	2.5	2.4	2.2	1.8	2.5	2.7	1.1	2.4	2.5	2.5	3.3	2.4	2.0	-0.6	-0.0	2.5	1.3	2.7	2.6	2.2	2.3	2.0
Frequency of tenseness / restlessness in last 2 weeks	3.8	5.9	11.4	-3.1	-2.1	-2.8	-2.7	-3.2	-2.5	-1.5	-1.8	-2.4	-2.5	-2.9	-3.4	-2.9	-1.9	2.2	0.5	-2.0	-1.0	-2.0	-2.5	-2.6	-2.5	-2.7
Diverticular disease/diverticulitis (self-reported)	3.7	4.4	11.0	-2.1	-1.8	-2.1	-2.5	-1.9	-2.3	-1.3	-0.8	-2.0	-1.9	-2.0	-3.2	-2.0	-1.9	3.3	2.2	-2.6	-1.2	-1.6	-2.1	-1.9	-1.6	-2.0
Medication: Ibuprofen (e.g. Nurofen)	3.7	4.7	11.7	-2.3	-1.8	-2.4	-2.9	-1.8	-2.4	-1.7	-0.3	-2.1	-2.2	-2.2	-3.4	-1.8	-2.3	2.9	1.9	-2.8	-1.1	-1.8	-2.2	-1.9	-1.8	-1.9
Illnesses of father: High blood pressure	3.6	4.5	17.8	2.3	1.9	1.8	4.2	3.7	1.9	1.3	1.2	2.2	1.9	2.0	2.5	3.2	0.3	-2.0	-0.0	1.3	1.9	1.9	1.9	1.7	1.8	1.6
Deep venous thrombosis (DVT) (self-reported)	3.5	4.5	9.5	2.2	2.4	2.2	2.1	1.6	2.3	2.8	1.1	2.3	2.4	2.3	3.1	2.2	2.1	-0.3	0.3	2.4	1.4	2.5	2.4	2.0	2.1	1.8
Illnesses of father: Heart disease	3.4	4.7	12.0	2.8	1.9	2.4	0.6	2.9	2.5	0.9	1.7	2.1	2.5	2.5	3.5	2.7	0.7	-1.4	0.5	1.5	0.9	2.6	2.5	2.4	2.7	2.2
Medication: Omeprazole (e.g. Zanprol)	3.4	4.1	7.2	2.2	2.4	2.0	1.9	2.0	2.2	1.6	1.3	2.5	2.2	2.1	2.7	2.4	1.9	-0.6	0.3	2.0	2.0	2.4	2.1	2.1	2.2	1.7
Medication: Ramipril	3.3	4.2	13.1	2.9	1.3	2.2	2.0	3.6	2.4	0.1	0.2	1.8	2.3	2.3	2.8	3.0	0.2	-2.1	-0.3	1.0	1.2	2.2	2.2	2.0	2.3	1.8
Mouth/teeth dental problems: Loose teeth	3.3	3.9	12.3	-2.0	-2.4	-2.3	-0.4	-1.3	-2.1	-2.0	-3.5	-2.4	-2.0	-2.2	-1.7	-1.6	-1.5	-0.1	0.1	-2.0	-1.7	-1.8	-1.9	-2.3	-2.2	-2.3
Arm predicted mass (left)	3.3	17.0	43.2	-3.9	-4.4	-4.1	-5.0	-4.3	-4.1	-3.6	-2.0	-3.9	-3.5	-3.6	-6.6	-4.3	-3.7	6.4	4.5	-5.8	-2.7	-2.6	-3.5	-3.2	-2.7	-2.8
Lupus	3.2	4.9	13.1	2.4	2.1	2.5	2.6	2.2	2.4	1.6	1.1	2.2	2.2	2.4	3.6	2.5	1.6	-3.1	-1.1	2.3	2.2	2.1	2.0	1.7	1.8	1.5
Medication: Lansoprazole	3.2	3.6	9.3	2.1	1.9	2.0	1.2	0.8	2.1	1.4	1.8	2.0	2.0	2.1	3.0	2.2	2.0	-1.5	0.8	1.8	2.4	2.0	2.0	1.8	1.7	1.7
Medication: Lisinopril	3.2	4.1	8.6	2.1	2.2	2.1	2.4	2.1	2.0	1.9	1.4	2.4	2.1	2.2	2.9	2.5	1.7	-1.3	-0.0	2.0	1.1	2.3	2.2	2.0	2.0	1.7
Arm fat-free mass (left)	3.2	16.4	42.9	-3.9	-4.3	-4.0	-4.9	-4.3	-4.0	-3.5	-1.9	-3.8	-3.5	-3.5	-6.5	-4.3	-3.6	6.4	4.3	-5.7	-2.4	-2.5	-3.4	-3.2	-2.6	-2.7
Heart attack/myocardial infarction (self-reported)	3.2	4.2	11.8	2.6	1.4	2.2	0.8	2.6	2.6	-0.2	0.0	1.7	2.4	2.3	3.4	2.7	0.4	-3.1	-1.5	1.9	1.2	1.9	2.2	1.9	2.0	1.5
Frequency of depressed mood in last 2 weeks	3.1	4.3	7.6	-2.7	-1.7	-2.5	-1.3	-2.3	-2.3	-0.9	-2.0	-2.1	-2.4	-2.6	-2.5	-2.4	-1.2	1.3	-0.1	-1.2	-1.8	-1.9	-2.4	-2.5	-2.5	-2.5
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	6.0	1.8	2.3	2.0	1.8	2.0	1.8	2.2	1.6	2.3	1.7	1.9	2.0	1.8	2.5	-0.3	-0.1	2.2	2.0	1.7	1.7	2.1	1.8	1.9
Neck or shoulder pain in last month	3.1	4.4	11.5	-1.6	-2.6	-2.2	-0.4	-0.2	-1.9	-3.4	-2.6	-2.2	-2.0	-2.1	-1.9	-1.0	-3.0	-1.7	-0.4	-2.6	-2.1	-2.3	-2.2	-2.3	-2.1	-2.2
Comparative height size at age 10	3.1	16.9	33.6	-4.5	-4.1	-4.6	-4.5	-4.8	-4.5	-3.2	-2.5	-4.4	-4.1	-4.2	-5.8	-4.6	-2.7	4.7	3.2	-4.8	-2.9	-3.4	-4.1	-4.1	-3.7	-3.5
Medication: Aspirin	3.1	4.0	8.5	2.4	2.2	2.2	0.5	2.0	2.4	1.3	1.2	2.1	2.3	2.4	2.9	2.8	1.0	-1.0	-0.2	2.2	1.3	2.4	2.3	2.2	2.2	1.8
Trunk predicted mass	3.0	16.9	42.3	-4.2	-4.2	-4.2	-4.8	-4.6	-4.2	-3.4	-2.0	-4.0	-3.7	-3.8	-6.5	-4.6	-3.4	5.8	4.0	-5.4	-2.9	-2.9	-3.6	-3.4	-3.0	-2.9
Migraine (self-reported)	3.0	3.7	6.9	-2.4	-2.1	-2.4	0.3	-1.3	-2.1	-2.0	-2.6	-2.0	-2.2	-2.3	-2.2	-2.0	-0.9	-0.3	-0.2	-1.6	-1.1	-2.1	-2.1	-2.2	-2.3	-2.1
Pack years adult smoking proportion	2.9	4.4	8.4	-2.5	-2.0	-2.4	-1.9	-2.1	-2.4	-1.6	-1.8	-2.3	-2.4	-2.4	-2.9	-2.0	-1.8	1.5	1.0	-2.1	-0.8	-2.0	-2.4	-2.4	-2.2	-2.5
Trunk fat-free mass	2.9	16.6	41.8	-4.1	-4.2	-4.2	-4.8	-4.6	-4.2	-3.3	-1.9	-3.9	-3.6	-3.7	-6.5	-4.5	-3.3	5.9	4.0	-5.3	-2.9	-2.9	-3.6	-3.4	-3.0	-2.8
Illnesses of mother	2.9	3.6	7.6	-2.3	-1.7	-2.0	-1.0	-2.0	-2.1	-1.2	-2.5	-1.8	-2.0	-2.0	-2.8	-2.5	-0.3	1.4	0.8	-1.8	-1.3	-2.1	-2.0	-2.1	-2.1	-2.0
Medication: Ibuprofen	2.9	3.5	8.1	-2.1	-1.6	-2.2	-2.3	-1.5	-2.1	-1.6	-0.6	-1.9	-2.1	-2.1	-2.8	-1.6	-1.8	1.9	1.0	-2.3	-0.6	-1.9	-2.1	-1.9	-1.8	-1.8
Suffer from ‘nerves’	2.9	4.6	8.3	-2.6	-2.0	-2.6	-1.0	-2.3	-2.6	-1.5	-1.9	-2.3	-2.7	-2.6	-2.1	-2.1	-2.0	0.1	0.3	-1.8	-0.8	-2.3	-2.5	-2.6	-2.5	-2.9
Medication for cholesterol, blood pressure or diabetes	2.8	4.7	11.9	-2.8	-1.8	-2.3	-2.1	-3.3	-2.2	-1.1	-0.5	-2.2	-2.3	-2.6	-3.2	-3.4	-0.8	1.8	-0.8	-1.4	-0.8	-2.4	-2.3	-2.1	-2.3	-1.8
HbA1C	2.7	3.0	9.1	-2.5	-0.1	-2.1	-0.2	-2.8	-2.1	1.3	0.4	-0.8	-1.7	-2.0	-2.8	-2.0	0.4	3.0	0.8	-0.8	-1.5	-1.7	-1.8	-1.4	-1.7	-1.4
Arm fat-free mass (right)	2.7	14.1	36.6	-3.6	-4.0	-3.7	-4.7	-4.3	-3.6	-3.2	-1.7	-3.6	-3.1	-3.2	-6.1	-4.0	-3.5	5.8	3.7	-5.2	-2.5	-2.4	-3.1	-3.0	-2.5	-2.5
High blood pressure (mother)	2.6	3.6	9.1	2.5	1.3	2.1	1.0	3.0	2.1	0.5	1.6	1.8	2.1	2.2	2.3	3.0	-0.3	-1.0	0.6	0.7	1.0	2.3	2.0	2.1	2.4	1.9
Heart attack	2.6	3.3	9.9	2.4	1.1	2.0	0.3	2.3	2.3	-0.4	-0.2	1.4	2.1	2.0	3.1	2.4	0.2	-2.9	-1.4	1.6	0.8	1.7	2.0	1.7	1.8	1.3
Neuroticism score	2.6	5.4	9.2	-3.0	-2.1	-2.9	-1.8	-2.7	-2.6	-1.6	-2.0	-2.4	-2.8	-3.0	-2.5	-3.0	-1.0	0.6	0.1	-1.6	-0.4	-2.4	-2.8	-2.9	-2.8	-2.9
Arm predicted mass (right)	2.6	13.4	35.4	-3.4	-3.9	-3.6	-4.7	-4.1	-3.5	-3.2	-1.5	-3.4	-3.0	-3.1	-6.0	-3.9	-3.4	5.8	3.6	-5.1	-2.4	-2.3	-2.9	-2.8	-2.3	-2.3
Ever depressed for a whole week	2.6	3.1	12.5	-1.7	-1.8	-1.7	-3.5	-2.2	-1.4	-2.2	-1.7	-1.9	-1.4	-1.7	-1.9	-2.3	-0.6	1.1	1.0	-1.8	-1.8	-1.2	-1.4	-1.6	-1.3	-1.4
Mouth/teeth dental problems: Bleeding gums	2.5	3.3	5.8	2.1	2.1	1.7	0.9	1.9	2.0	1.4	1.8	2.2	2.1	1.9	2.0	2.2	0.9	-0.4	-0.2	1.5	-0.3	2.2	2.1	2.1	2.2	2.4
Whole body water mass	2.5	14.0	39.9	-3.6	-3.7	-3.7	-4.5	-4.1	-3.7	-2.9	-1.6	-3.4	-3.1	-3.2	-6.2	-3.9	-3.2	6.3	4.2	-5.0	-2.5	-2.3	-3.1	-2.9	-2.4	-2.4
Basal metabolic rate	2.5	14.0	37.3	-3.6	-3.8	-3.8	-4.3	-4.0	-3.7	-3.2	-1.7	-3.4	-3.2	-3.2	-6.1	-3.8	-3.4	6.1	4.2	-5.1	-2.7	-2.2	-3.1	-2.9	-2.4	-2.4
Alcohol drinker status: Previous	2.5	2.9	6.9	1.5	2.1	1.5	1.7	0.7	1.6	2.6	2.3	2.0	1.8	1.9	1.7	2.0	1.6	0.6	0.7	1.7	1.0	1.9	1.6	1.6	1.7	1.7
Verbal and Numeric Reasoning (VNR)	2.4	5.7	11.2	2.8	1.9	2.9	-1.5	1.8	2.9	1.3	2.2	2.3	3.0	2.9	1.8	1.9	1.7	1.8	-0.2	1.8	1.8	2.8	3.0	3.3	3.3	3.2
Weight	2.4	11.9	28.5	-3.2	-3.8	-3.6	-3.4	-3.3	-3.4	-3.4	-2.3	-3.3	-3.1	-3.0	-5.3	-3.1	-3.4	4.7	3.7	-4.8	-3.3	-2.2	-3.1	-2.9	-2.4	-2.6
Whole body fat-free mass	2.4	13.5	38.8	-3.6	-3.6	-3.7	-4.4	-4.0	-3.6	-2.9	-1.5	-3.3	-3.1	-3.2	-6.1	-3.9	-3.2	6.2	4.2	-4.9	-2.5	-2.2	-3.0	-2.8	-2.3	-2.3
Mean Putamen Volume	2.3	2.7	5.4	-1.5	-2.3	-1.7	-0.4	-1.2	-1.7	-2.2	-2.1	-2.0	-1.7	-1.6	-1.4	-1.5	-1.7	-0.6	1.2	-1.8	-1.7	-1.6	-1.6	-1.6	-1.6	-1.6
Supplements: Calcium	2.3	2.5	5.0	1.5	1.8	2.0	0.2	1.1	1.8	1.8	1.3	1.7	1.6	1.7	2.1	1.3	2.0	-1.1	-1.3	2.2	1.1	1.1	1.5	1.8	1.4	1.5
Pack years of smoking	2.3	3.3	6.6	-2.2	-1.5	-2.0	-2.1	-2.1	-2.1	-1.2	-1.6	-1.9	-2.0	-2.0	-2.6	-1.9	-1.2	1.7	1.1	-1.7	-0.5	-1.6	-2.1	-2.0	-1.8	-2.1
Waist circumference	2.2	7.9	15.5	-2.7	-3.4	-3.2	-1.1	-2.4	-3.1	-3.1	-3.0	-2.9	-2.9	-2.7	-3.7	-2.2	-2.7	1.9	2.5	-3.9	-2.8	-2.2	-2.9	-2.9	-2.5	-2.7
Fluid intelligence score	2.2	4.6	7.7	2.2	2.0	2.6	-0.2	1.2	2.7	1.9	2.2	2.2	2.5	2.4	2.1	1.4	1.9	0.7	-1.5	2.8	2.0	2.3	2.5	2.8	2.5	2.5
Pulse wave Arterial Stiffness index	2.2	2.5	19.7	1.3	-0.8	0.6	1.1	2.7	0.8	-2.4	-2.6	-0.2	0.5	0.6	2.1	1.8	-0.8	-4.4	-1.5	-0.7	-1.5	-0.0	0.4	-0.1	0.4	0.0
Pulse wave peak to peak time	2.1	2.5	19.1	-1.3	0.8	-0.6	-1.1	-2.7	-0.8	2.3	2.5	0.1	-0.5	-0.6	-2.0	-1.8	0.9	4.4	1.4	0.8	1.6	-0.0	-0.4	0.1	-0.4	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.1	2.5	4.9	1.6	1.9	1.5	2.2	1.4	1.5	1.6	1.2	1.7	1.4	1.5	2.1	2.0	1.6	-1.1	-0.3	1.7	2.0	1.3	1.4	1.3	1.3	1.3
Risk taking	2.0	2.9	6.4	-2.1	-1.5	-2.0	-0.7	-1.5	-2.0	-1.1	-0.9	-1.7	-1.9	-2.0	-2.5	-2.0	-1.6	1.6	0.6	-1.7	0.4	-1.8	-1.9	-1.8	-1.8	-2.0
Cholesterol lowering medication	2.0	2.9	9.9	2.2	0.9	1.9	1.6	2.2	2.0	-0.4	-0.0	1.4	1.7	1.9	2.7	1.9	0.7	-3.1	-1.4	1.4	1.3	1.1	1.6	1.6	1.5	1.4
Intelligence (Savage-Jansen 2018)	1.9	5.8	10.8	2.6	2.2	3.1	-1.6	1.7	2.8	1.6	2.1	2.5	2.8	2.9	2.4	1.5	2.4	1.4	-0.2	1.9	2.1	2.8	2.8	3.2	3.3	3.0
Neuroticism (Nagel 2018)	1.9	4.5	7.9	-2.7	-2.0	-2.7	-1.4	-2.0	-2.3	-1.7	-1.8	-2.2	-2.5	-2.8	-2.2	-2.6	-1.2	0.3	-0.3	-1.5	-0.4	-2.3	-2.5	-2.5	-2.6	-2.6
Supplements: Zinc	1.9	2.0	6.1	-1.0	-1.2	-1.2	-1.7	-0.6	-1.5	-1.2	-0.7	-1.3	-1.5	-1.2	-2.1	-1.1	-2.1	1.6	1.2	-1.9	-2.5	-1.1	-1.4	-1.0	-0.7	-1.1
Ever unenthusiastic/disinterested for a whole week	1.9	2.3	8.0	-1.5	-1.5	-1.6	-2.8	-1.5	-1.3	-2.0	-1.1	-1.7	-1.4	-1.6	-2.0	-1.6	-0.9	1.0	0.7	-1.7	-1.2	-1.2	-1.4	-1.5	-1.2	-1.3
Alcohol intake versus 10 years previously	1.9	2.8	6.8	1.8	1.5	1.7	1.7	2.2	2.1	0.7	0.5	1.7	1.8	1.7	2.6	1.8	0.7	-2.4	-2.0	1.8	0.8	1.4	1.9	1.5	1.3	1.3
Leg fat mass (right)	1.9	7.6	16.1	-2.5	-3.2	-2.9	-1.8	-2.4	-2.8	-2.8	-2.3	-2.7	-2.5	-2.5	-4.0	-2.1	-3.2	3.2	3.1	-4.0	-2.7	-1.6	-2.6	-2.5	-2.0	-2.4
High cholesterol (Self-reported)	1.9	3.3	8.5	2.3	1.4	2.1	1.1	2.9	2.1	0.4	1.0	1.8	1.9	2.2	2.2	2.0	0.6	-1.8	-1.3	1.5	1.9	1.6	1.9	2.0	2.0	1.9
Type 2 Diabetes (T2D) (2018)	1.8	3.3	9.4	2.4	1.3	2.0	1.6	2.5	2.1	0.3	0.1	1.6	2.0	2.2	2.8	3.1	0.9	-1.5	0.0	1.1	1.1	2.0	2.0	1.8	1.9	1.5
Relative age voice broke	1.8	2.7	7.6	2.2	0.7	2.0	-0.5	2.8	2.1	-0.6	-0.2	1.4	2.1	1.9	2.3	1.2	0.8	-1.3	0.3	0.2	-1.1	1.9	2.0	1.9	2.2	1.8
Ever taken oral contraceptive pill	1.8	2.0	7.5	-0.6	-2.2	-0.9	-2.5	-0.1	-0.9	-2.7	-1.7	-1.8	-0.9	-0.9	-0.9	-0.9	-2.5	-0.3	0.5	-2.1	-1.3	-0.7	-0.9	-1.0	-0.6	-1.1
Leg fat-free mass (left)	1.7	8.8	34.5	-2.8	-2.6	-3.0	-3.2	-3.2	-2.9	-2.0	-1.0	-2.4	-2.3	-2.4	-5.1	-2.8	-2.6	5.9	4.0	-4.0	-2.1	-1.3	-2.3	-2.2	-1.7	-1.8
Medication for pain relief, constipation, heartburn	1.7	2.9	5.8	-2.0	-2.0	-1.7	-0.3	-2.1	-2.0	-0.6	-1.3	-2.2	-1.9	-2.0	-1.9	-2.4	-1.2	0.4	-0.8	-1.0	-1.6	-2.2	-1.8	-1.9	-2.1	-1.7
Whole body fat mass	1.7	6.9	15.1	-2.3	-3.1	-2.8	-1.6	-2.1	-2.6	-2.9	-2.5	-2.6	-2.4	-2.3	-3.7	-1.9	-3.0	2.8	3.1	-3.9	-2.9	-1.6	-2.5	-2.4	-1.9	-2.2
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	9.9	-1.4	-1.8	-1.3	-3.1	-2.0	-1.5	-1.9	-1.1	-1.8	-1.5	-1.5	-2.4	-2.2	-0.8	1.4	0.6	-1.9	-0.2	-1.5	-1.5	-1.3	-1.2	-1.2
Medication: Aspirin	1.7	2.3	6.3	1.8	1.5	1.6	0.5	1.5	1.8	0.9	0.6	1.5	1.7	1.8	2.5	2.2	0.7	-1.2	-0.1	1.8	0.8	1.7	1.7	1.6	1.5	1.2
Leg fat mass (left)	1.7	6.5	14.7	-2.2	-3.0	-2.6	-1.7	-2.2	-2.5	-2.6	-2.0	-2.5	-2.3	-2.2	-3.8	-2.0	-3.1	3.2	2.9	-3.8	-2.5	-1.5	-2.4	-2.3	-1.8	-2.1
Leg predicted mass (left)	1.6	8.6	35.1	-2.7	-2.6	-2.9	-3.2	-3.2	-2.8	-1.9	-1.0	-2.3	-2.3	-2.4	-5.0	-2.7	-2.6	5.9	4.0	-3.9	-2.0	-1.3	-2.3	-2.1	-1.6	-1.7
Diabetes diagnosed by doctor	1.6	2.7	7.5	1.9	1.4	1.6	2.0	2.3	1.7	0.5	0.4	1.4	1.4	1.7	2.5	2.7	0.8	-1.9	-1.2	1.5	2.2	1.2	1.4	1.4	1.3	1.0
Ulcerative Colitis (UC)	1.5	2.9	9.9	1.9	1.1	1.9	0.0	1.8	2.2	0.6	0.4	1.4	1.8	1.9	3.1	2.0	1.2	-2.1	-1.5	2.0	1.0	1.5	1.8	1.7	1.6	1.6
Allergy or Eczema	1.5	4.0	32.7	-1.9	-0.2	-1.6	-2.8	-2.9	-1.6	1.0	1.4	-0.7	-1.1	-1.4	-3.9	-2.2	-0.5	5.7	1.1	-1.2	-1.2	-0.7	-1.1	-0.9	-0.8	-0.3
Neuroticism	1.5	3.7	6.5	-2.4	-2.0	-2.3	-1.4	-2.2	-2.0	-1.8	-1.8	-2.0	-2.2	-2.5	-1.8	-2.6	-1.0	-0.0	-0.6	-1.2	-0.4	-2.1	-2.2	-2.3	-2.4	-2.2
Sensitivity / hurt feelings	1.5	2.6	5.7	1.2	2.3	1.4	0.0	0.5	1.5	2.1	2.4	2.2	1.6	1.4	0.8	1.0	2.3	1.4	0.4	1.6	1.5	1.7	1.6	1.8	1.6	1.8
Relative age of first facial hair	1.5	3.0	7.3	2.2	1.5	2.1	0.8	2.7	2.1	0.7	0.8	1.9	2.1	2.0	2.4	1.8	0.9	-1.0	-0.6	1.2	0.0	2.1	2.0	2.0	2.1	1.9
Trunk fat mass	1.5	6.3	14.0	-2.1	-3.1	-2.6	-1.4	-1.9	-2.5	-3.0	-2.5	-2.5	-2.3	-2.2	-3.4	-1.6	-2.9	2.4	2.9	-3.7	-2.9	-1.5	-2.4	-2.3	-1.8	-2.2
Average weekly beer plus cider intake	1.5	2.1	3.8	-1.8	-1.3	-1.7	1.4	-1.3	-1.8	-0.5	-1.7	-1.3	-1.9	-1.7	-1.4	-1.6	-0.8	-0.2	-0.1	-0.8	0.2	-1.7	-1.7	-1.8	-1.9	-2.0
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	4.6	1.4	1.6	1.4	1.2	1.7	1.4	1.3	-0.1	1.6	1.5	1.4	2.1	1.6	1.3	-0.7	0.3	1.1	0.1	1.8	1.5	1.2	1.4	0.9
Angina	1.4	1.8	4.5	1.8	0.9	1.5	0.0	1.6	1.8	-0.1	0.5	1.1	1.5	1.4	2.1	1.8	-0.2	-1.8	-0.6	1.3	1.1	1.7	1.4	1.4	1.4	0.8
Hayfever, allergic rhinitis or eczema	1.4	3.0	25.8	-1.5	-0.1	-1.2	-2.4	-2.4	-1.4	1.1	1.2	-0.5	-0.9	-1.0	-3.3	-1.6	-0.4	5.1	1.3	-0.9	-1.5	-0.4	-0.9	-0.6	-0.5	-0.0
Falls in the last year	1.4	1.9	5.0	-1.3	-1.4	-1.5	0.4	-0.0	-1.4	-1.5	-2.2	-1.2	-1.4	-1.5	-1.1	-0.9	-1.3	-0.8	0.4	-1.7	-2.2	-1.2	-1.4	-1.6	-1.4	-1.6
Impedance of arm (left)	1.4	6.5	24.1	2.3	2.4	2.2	3.7	3.2	2.4	1.5	0.2	2.1	2.0	1.9	4.6	2.8	2.6	-4.9	-2.4	3.2	0.7	1.5	2.0	1.6	1.3	1.3
Arm fat mass (right)	1.4	5.7	13.0	-2.0	-2.8	-2.5	-1.2	-1.8	-2.4	-2.6	-2.2	-2.3	-2.1	-2.0	-3.6	-1.6	-2.8	3.1	2.9	-3.6	-2.4	-1.3	-2.2	-2.0	-1.6	-1.9
Leg fat percentage (right)	1.4	5.0	9.6	-2.0	-2.8	-2.4	-0.9	-1.7	-2.3	-2.6	-2.4	-2.3	-2.3	-2.1	-2.9	-1.6	-2.6	1.3	1.8	-3.1	-2.5	-1.6	-2.3	-2.2	-1.9	-2.2
Exposure to tobacco smoke outside home	1.4	1.9	5.6	1.1	1.6	0.9	2.3	1.1	0.9	1.5	1.6	1.3	0.9	1.1	1.6	2.4	0.3	-1.2	-1.2	1.8	2.4	1.0	0.9	0.7	0.6	0.5
Age started oral contraceptive pill	1.4	1.7	4.5	1.5	1.3	1.5	0.2	0.8	1.5	1.1	1.5	1.1	1.3	1.4	1.5	1.2	0.5	-0.9	-2.1	1.8	1.1	1.0	1.4	1.4	1.2	1.5
Type 2 Diabetes (T2D) (2012)	1.3	1.4	10.2	0.8	0.0	0.7	0.9	1.0	1.4	-0.9	0.5	0.4	1.0	0.5	1.2	0.8	-0.4	-2.5	-3.2	1.0	2.1	0.3	0.9	0.6	0.4	0.6
Medication for hormone replacement therapy	1.3	1.4	2.6	-1.4	-1.1	-1.3	0.4	-0.9	-1.1	-0.9	-1.5	-1.1	-1.3	-1.5	-0.6	-1.1	-0.3	-1.6	-1.0	-0.5	-1.3	-1.5	-1.3	-1.4	-1.6	-1.3
Mouth/teeth dental problems	1.3	1.9	3.9	1.2	1.7	1.6	0.9	1.0	1.5	2.0	1.9	1.6	1.5	1.5	0.9	0.9	1.1	1.2	0.2	1.6	0.9	1.6	1.5	1.6	1.5	1.6
Medication: Omeprazole	1.3	1.5	2.6	1.4	1.4	1.1	1.4	1.6	1.3	0.7	0.5	1.4	1.4	1.3	1.6	1.5	0.8	0.1	0.5	1.0	1.2	1.6	1.3	1.3	1.5	1.0
Leg fat-free mass (right)	1.3	6.9	37.6	-2.2	-2.1	-2.4	-3.2	-2.8	-2.3	-1.5	-0.4	-1.8	-1.8	-1.8	-4.7	-2.5	-2.3	6.1	3.7	-3.5	-1.6	-0.9	-1.7	-1.5	-1.1	-1.1
Miserableness	1.3	2.2	4.2	-1.8	-1.3	-1.8	-1.7	-1.6	-1.5	-1.0	-1.0	-1.3	-1.4	-1.7	-2.0	-2.1	-0.8	1.5	0.9	-1.6	-2.0	-1.0	-1.5	-1.6	-1.4	-1.2
Guilty feelings	1.3	2.0	3.8	-1.8	-1.2	-1.6	-0.6	-1.5	-1.5	-0.8	-1.3	-1.5	-1.6	-1.8	-1.1	-1.3	-0.8	-0.6	-1.8	-0.4	0.4	-1.7	-1.6	-1.8	-1.9	-1.9
Fractured/broken bones in last 5 years	1.3	1.7	3.5	1.6	0.7	1.3	0.9	1.9	1.7	-0.4	0.5	1.2	1.6	1.3	1.8	1.6	0.4	-1.7	-0.6	0.8	1.2	1.4	1.5	1.3	1.3	1.1
Worry (Nagel 2018)	1.2	2.5	5.0	-2.0	-1.4	-2.1	-1.0	-1.7	-1.9	-1.1	-1.5	-1.6	-2.0	-2.1	-1.3	-1.6	-1.1	0.4	1.1	-1.1	0.1	-1.4	-1.9	-1.9	-1.9	-2.2
Lung FVC	1.2	6.2	15.1	2.1	3.3	2.4	2.2	1.3	2.4	3.6	2.6	3.0	2.3	2.3	3.4	2.3	2.6	-1.4	-0.7	3.9	2.2	2.4	2.2	2.2	1.9	1.8
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	2.4	-1.1	-1.1	-1.3	-0.3	-0.3	-1.6	-0.8	-1.2	-1.1	-1.5	-1.2	-1.3	-0.5	-1.2	0.8	1.0	-1.3	-1.0	-1.0	-1.5	-1.3	-1.1	-1.3
Pulse rate	1.2	2.0	4.0	1.7	1.3	1.7	-0.1	1.3	1.7	0.4	0.1	1.6	1.7	1.7	2.0	1.6	1.6	-1.2	-0.2	0.9	-0.6	1.9	1.7	1.5	1.7	1.2
Medication: Amlodipine	1.2	1.7	4.1	1.3	1.3	1.3	0.7	1.1	1.4	1.0	1.2	1.2	1.1	1.3	1.8	1.8	0.8	-1.4	-1.2	1.8	2.0	1.1	1.1	1.3	1.1	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.5	3.3	1.6	1.0	1.5	-1.1	1.2	1.4	0.4	0.4	1.2	1.4	1.6	0.9	1.0	0.7	0.8	1.2	0.3	0.1	1.8	1.5	1.4	1.8	1.4
Friendships satisfaction	1.2	1.5	10.4	0.1	1.3	0.2	-1.1	-0.7	0.6	1.5	2.1	1.1	0.8	0.3	-0.6	0.2	0.7	3.2	1.1	0.6	2.3	1.1	0.7	0.9	0.9	0.9
Leg predicted mass (right)	1.2	6.6	37.6	-2.1	-2.0	-2.3	-3.2	-2.7	-2.2	-1.4	-0.3	-1.7	-1.7	-1.7	-4.6	-2.4	-2.2	6.1	3.7	-3.4	-1.6	-0.8	-1.6	-1.4	-1.0	-1.0
Ever used hormone-replacement therapy (HRT)	1.1	1.4	5.6	-1.0	-1.4	-0.9	-0.6	-1.4	-0.7	-1.1	-1.4	-1.3	-1.1	-1.1	-0.5	-1.3	-0.0	-1.5	-2.4	0.2	-1.0	-1.7	-1.0	-1.0	-1.3	-0.8
Diabetes (father)	1.1	1.3	2.5	1.5	0.6	1.2	0.2	1.0	1.1	-0.2	0.4	1.1	1.2	1.4	1.5	1.1	1.0	-1.6	1.1	0.0	-1.5	1.3	1.2	0.9	1.2	1.5
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	3.7	0.8	1.3	1.0	0.4	0.2	1.1	1.2	1.6	1.3	1.2	1.0	0.3	0.3	1.3	1.4	-0.0	1.1	1.9	0.8	1.2	1.4	1.2	1.6
Body mass index (BMI)	1.1	4.5	11.9	-1.8	-2.5	-2.2	-1.3	-1.9	-2.1	-2.1	-1.5	-1.9	-1.9	-1.8	-3.5	-1.5	-2.7	3.0	2.3	-3.0	-2.1	-1.2	-2.0	-1.8	-1.4	-1.6
Standing height	1.1	11.1	21.9	-3.3	-3.6	-3.4	-4.7	-3.4	-3.3	-3.5	-2.3	-3.5	-2.9	-3.1	-4.5	-3.8	-2.1	3.6	3.3	-4.5	-3.0	-2.5	-2.9	-2.9	-2.5	-2.5
Comparative body size at age 10	1.1	3.0	5.7	2.0	1.6	2.0	-0.3	1.2	2.1	1.5	2.0	1.9	2.0	2.1	1.2	1.8	0.6	0.7	-1.3	2.0	0.0	1.9	1.9	2.2	2.0	2.4
Leg pain on walking	1.1	1.4	5.4	-1.1	-1.3	-1.2	-0.2	-0.2	-1.2	-1.2	-1.6	-0.9	-1.0	-1.1	-1.2	-1.0	-0.7	0.8	2.3	-2.1	0.1	-0.3	-1.0	-1.2	-0.8	-1.3
Arm fat mass (left)	1.1	4.4	10.8	-1.7	-2.5	-2.1	-1.1	-1.7	-2.1	-2.2	-1.8	-1.9	-1.8	-1.7	-3.3	-1.3	-2.5	3.0	2.6	-3.2	-2.2	-1.1	-1.9	-1.7	-1.3	-1.6
Irritable Bowel Disease (IBD)	1.0	2.4	10.8	1.5	0.7	1.4	0.7	1.6	1.7	0.1	0.1	0.8	1.2	1.3	3.3	2.1	0.3	-3.1	-2.5	1.9	0.9	0.9	1.2	1.1	1.0	0.9
Height	1.0	19.2	39.8	-4.0	-5.1	-4.3	-6.3	-4.1	-4.3	-5.2	-3.8	-5.0	-3.8	-4.0	-5.4	-4.9	-3.2	3.9	3.9	-6.1	-4.0	-3.4	-3.8	-3.9	-3.2	-3.3
Stomach or abdominal pain in last month	1.0	1.2	3.7	-1.0	-1.2	-1.2	0.1	0.1	-1.1	-1.9	-1.5	-1.0	-1.2	-1.3	-0.7	-0.8	-0.7	-1.3	0.6	-1.5	-0.2	-1.2	-1.1	-1.3	-1.2	-1.2
Number of children fathered	1.0	1.1	5.6	-0.7	-1.0	-0.8	-1.8	-1.2	-0.8	-1.0	-0.4	-0.9	-0.7	-0.6	-1.1	-1.2	-0.8	1.5	2.4	-1.5	-1.1	-0.3	-0.7	-0.6	-0.3	-0.6
Angina (self-reported)	1.0	1.3	3.6	1.4	0.8	1.2	0.1	1.3	1.5	-0.0	0.4	0.9	1.3	1.1	1.9	1.6	-0.2	-1.7	-0.6	1.2	1.2	1.5	1.2	1.1	1.2	0.5
Leg fat percentage (left)	1.0	3.5	7.5	-1.6	-2.5	-1.9	-0.9	-1.3	-1.9	-2.3	-1.9	-1.9	-1.8	-1.6	-2.6	-1.3	-2.3	1.5	1.5	-2.7	-2.2	-1.2	-1.9	-1.8	-1.4	-1.7
Waist Hip Ratio (WHR)	0.9	3.9	12.5	2.3	1.4	1.9	3.0	2.8	1.8	0.3	-0.8	1.7	1.7	2.0	3.4	2.2	2.3	-3.5	-0.1	1.1	0.9	1.7	1.8	1.3	1.5	1.2
Tanning	0.9	10.6	20.0	4.0	3.3	3.6	2.3	3.2	4.0	2.1	2.0	3.8	3.9	3.8	4.5	4.2	1.9	-2.5	-0.1	3.0	0.7	4.0	3.8	3.3	3.6	3.2
Allergy	0.9	2.2	24.1	0.8	-0.5	0.5	2.5	1.9	0.6	-1.6	-1.1	-0.2	0.2	0.2	2.4	1.2	-0.4	-4.9	-1.4	0.4	1.0	-0.4	0.1	-0.0	-0.2	-0.5
Qualifications: A levels/AS levels or equivalent	0.9	2.1	16.7	-0.2	1.4	0.3	-1.5	-0.5	0.4	1.9	1.6	1.4	0.8	0.3	-0.8	-0.7	1.6	4.1	2.8	0.1	0.3	1.8	0.8	0.9	1.1	0.6
Breastfed as a baby	0.9	1.2	7.1	-0.0	0.8	0.5	-2.7	-1.4	0.4	1.2	0.6	0.5	0.6	0.4	0.5	-0.8	1.9	1.8	1.7	0.4	0.5	1.0	0.8	0.5	0.7	0.3
Loud music exposure frequency	0.9	0.9	5.6	-0.3	-0.7	-0.6	0.5	0.4	-0.6	-1.4	-1.1	-0.6	-0.7	-0.6	0.0	0.3	-1.4	-2.4	-0.4	-0.8	-1.8	-0.9	-0.8	-1.0	-0.8	-0.9
Had major operations	0.9	1.1	3.1	1.1	0.8	1.3	-1.2	1.2	1.2	0.0	-0.9	0.9	1.1	1.1	1.4	0.3	1.8	-0.5	0.6	0.7	-0.3	1.1	1.0	1.2	1.3	1.0
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.4	-1.0	-1.5	-1.2	-0.6	-0.8	-1.1	-1.5	-1.3	-1.4	-1.2	-1.1	-0.9	-0.6	-0.9	-0.5	-0.1	-1.2	-0.4	-1.2	-1.1	-1.3	-1.1	-1.1
Alzheimer’s Disease (in mother)	0.8	0.9	6.1	0.4	1.1	0.5	-0.3	-0.6	0.6	1.2	2.5	0.9	0.7	0.6	0.1	0.3	0.1	1.2	0.5	0.8	1.9	0.8	0.7	0.9	0.7	0.8
Bipolar Disorder (2011)	0.8	0.8	1.4	-1.1	-0.9	-1.0	0.8	-1.0	-0.8	-0.4	-0.7	-0.8	-1.0	-1.1	-0.8	-0.8	-0.3	-0.5	-1.2	-0.2	0.0	-1.2	-1.0	-1.0	-1.2	-1.0
Lung FEV1/FVC ratio	0.8	4.1	22.8	-1.6	-1.2	-1.7	-2.6	-1.5	-2.0	-0.5	-0.0	-1.3	-1.4	-1.5	-3.1	-1.4	-1.7	4.8	3.3	-2.8	-3.0	-0.4	-1.3	-1.0	-0.4	-0.7
Medication: Metformin	0.8	1.1	2.2	-1.2	-0.8	-1.4	1.4	-0.6	-1.2	-0.6	-1.0	-0.9	-1.4	-1.2	-0.9	-0.2	-1.0	0.1	-0.2	-0.6	-0.0	-1.2	-1.3	-1.2	-1.4	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	3.0	-1.2	-1.7	-1.1	-1.5	-1.6	-1.6	-1.5	-1.5	-1.7	-1.5	-1.2	-1.4	-1.6	-0.5	0.7	1.3	-1.6	-0.9	-1.5	-1.4	-1.2	-1.1	-1.3
Chronic bronchitis/emphysema (father)	0.8	0.9	3.8	-0.7	-1.0	-0.7	-2.0	-1.1	-0.6	-0.4	-1.2	-0.9	-0.5	-0.6	-1.2	-1.1	-0.7	1.9	0.3	-0.9	-0.8	-0.1	-0.6	-0.6	-0.4	-0.8
Diabetes (self-reported)	0.8	1.2	4.0	1.3	0.7	1.1	1.4	2.0	1.1	-0.1	-0.2	0.9	1.0	1.1	1.8	2.0	0.3	-1.2	-0.3	0.6	1.3	0.9	0.9	1.0	0.9	0.6
Medication: Cholesterol lowering	0.8	1.2	4.5	1.5	0.6	1.0	0.9	2.1	1.1	-0.1	-0.3	0.9	1.1	1.2	1.6	1.9	-0.5	-1.2	-0.0	0.4	0.0	1.2	1.0	0.9	1.1	0.8
Tinnitus: Yes, now most or all of the time	0.8	0.9	7.3	-0.1	0.2	0.1	0.8	-1.0	0.2	0.5	0.4	-0.2	-0.2	-0.1	1.3	-0.1	0.3	-2.7	-2.4	1.8	-0.1	-0.7	-0.2	-0.2	-0.6	-0.1
Schizophrenia vs Biploar Disorder	0.7	0.9	1.9	1.3	0.4	1.1	-0.6	1.2	1.1	-0.0	0.1	0.5	1.3	1.2	1.4	0.7	0.6	-0.1	1.2	0.1	0.3	1.2	1.3	1.0	1.3	0.9
Triglycerides	0.7	1.1	5.6	0.2	-0.9	-0.3	1.2	2.0	0.1	-1.5	-1.9	-0.5	-0.1	-0.3	0.3	1.3	-1.5	-2.4	-1.6	-0.8	-0.2	-0.3	-0.2	-0.6	-0.4	-0.4
BMI	0.7	4.0	14.0	-1.8	-2.0	-2.1	-0.9	-2.0	-2.0	-1.3	-1.0	-1.6	-1.7	-1.6	-3.7	-1.3	-2.5	3.7	1.9	-2.7	-2.0	-1.1	-1.8	-1.6	-1.2	-1.5
Smoking Status	0.7	1.6	7.5	1.3	-0.7	1.0	-0.7	1.2	1.5	-1.4	-1.6	-0.1	1.2	1.0	2.3	1.4	-0.9	-2.7	-1.6	0.5	-0.2	0.9	1.1	0.6	0.8	0.4
Hair Pigment	0.7	20.2	32.9	-4.8	-5.7	-4.8	-2.0	-3.3	-4.8	-5.3	-4.3	-5.2	-4.8	-4.9	-5.7	-5.5	-4.7	1.4	-0.6	-5.2	-2.0	-5.0	-4.8	-4.6	-4.5	-4.5
Hearing difficulty/problems: Yes	0.7	1.0	8.6	0.5	0.0	0.6	0.9	0.4	0.6	-0.3	-0.4	0.2	0.1	0.4	1.3	0.4	1.0	-2.9	-2.5	1.4	1.1	-0.7	0.1	0.3	-0.1	0.2
Vitamin and mineral supplements	0.7	1.0	3.6	1.1	0.9	0.9	-0.1	0.4	1.3	0.9	0.2	0.7	1.2	1.0	1.9	0.8	0.8	-0.4	-0.5	1.3	0.7	1.1	1.3	1.0	1.1	1.1
Multivitamins +/- minerals	0.7	0.9	3.5	-1.1	-0.7	-0.9	0.1	-0.1	-1.3	-0.6	0.1	-0.6	-1.1	-1.1	-1.9	-1.0	-1.1	0.7	0.4	-1.3	-0.7	-0.8	-1.1	-1.1	-1.0	-1.1
Hearing difficulty/problems with background noise	0.7	1.2	3.6	-1.0	-1.2	-0.9	-0.7	-0.7	-1.1	-1.2	-1.9	-1.2	-1.4	-1.0	-0.7	-1.1	-0.1	-1.1	-0.6	-0.7	-0.3	-1.6	-1.4	-1.1	-1.2	-1.2
Had other major operations	0.7	0.8	3.2	1.1	0.5	0.9	-0.6	1.8	0.7	-0.3	0.2	0.9	1.0	1.0	0.3	0.6	-0.5	1.1	1.2	-0.7	-0.3	1.2	0.9	1.0	1.3	0.9
Medication: Simvastatin	0.7	1.0	5.2	1.2	0.1	0.8	1.3	1.6	0.9	-0.7	-0.6	0.5	0.7	0.9	1.6	1.4	-0.7	-2.3	-0.7	0.5	0.7	0.5	0.6	0.6	0.6	0.4
Impedance of arm (right)	0.7	3.3	20.0	1.3	1.3	1.2	3.3	2.6	1.2	0.6	-0.8	1.0	0.9	0.9	3.4	1.9	1.9	-4.5	-1.7	2.0	0.2	0.5	0.8	0.7	0.4	0.3
Worrier / anxious feelings	0.7	1.2	2.2	-1.3	-1.1	-1.4	-0.1	-1.1	-1.4	-0.6	-0.6	-1.1	-1.4	-1.3	-1.2	-1.1	-0.8	0.7	0.9	-1.1	0.7	-1.0	-1.3	-1.3	-1.3	-1.5
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	3.0	0.9	0.3	0.7	-1.1	1.7	0.9	-0.4	0.0	0.8	1.2	0.9	0.2	0.7	-0.1	0.6	0.5	-0.5	-0.7	1.6	1.2	0.9	1.3	1.1
Body fat percentage	0.7	2.8	6.8	-1.2	-2.2	-1.7	-0.2	-0.8	-1.5	-2.3	-2.1	-1.6	-1.5	-1.3	-2.0	-0.6	-2.2	1.2	2.0	-2.6	-2.2	-0.8	-1.5	-1.5	-1.1	-1.6
Health satisfaction	0.7	1.0	2.6	-1.1	-0.6	-1.1	-0.8	-0.9	-1.1	-0.4	-1.3	-0.9	-1.0	-1.0	-0.7	-0.6	-0.3	0.9	1.6	-1.0	0.5	-0.5	-1.1	-1.2	-1.1	-1.5
Alcohol intake frequency.	0.7	1.6	4.3	1.4	1.2	1.1	2.0	2.1	1.4	0.8	0.9	1.5	1.5	1.3	1.2	1.8	0.4	-0.9	-0.6	0.7	0.4	1.3	1.4	1.2	1.3	1.2
Illnesses of siblings: Diabetes	0.7	0.9	2.3	1.3	0.1	0.8	-0.2	1.5	1.1	-0.5	-0.2	0.6	1.2	1.1	1.1	1.4	-0.6	0.2	0.8	-0.6	-0.8	1.5	1.1	0.9	1.4	0.7
Long-standing illness, disability or infirmity	0.7	1.0	6.8	0.1	0.2	0.2	2.0	0.1	0.3	0.5	-1.3	0.1	0.1	0.1	2.1	0.8	1.1	-2.6	-1.2	1.3	-0.3	0.2	0.1	-0.3	-0.4	-0.4
Ever had bowel cancer screening	0.7	0.8	9.6	0.2	0.9	0.6	-0.3	-1.0	0.4	1.2	0.2	0.7	0.5	0.5	0.8	-0.5	3.1	-0.1	0.4	1.0	1.3	0.1	0.5	0.6	0.3	0.6
Eye problems/disorders: Cataract	0.7	0.8	2.0	-0.7	-1.0	-1.0	-0.1	0.5	-0.9	-1.4	-1.3	-1.0	-0.9	-1.0	-0.5	-0.4	-0.7	-0.7	0.3	-1.3	-0.5	-1.0	-0.9	-0.9	-0.8	-0.8
Osteoporosis (self-reported)	0.7	0.8	3.3	0.9	0.8	0.9	-0.5	1.1	1.1	-0.1	0.2	0.9	1.1	0.8	1.3	0.3	1.0	-1.8	-0.8	0.9	-0.8	0.7	1.0	0.8	0.8	0.9
Medication: Gliclazide	0.7	0.7	1.8	1.0	0.8	0.8	1.1	1.4	0.9	0.3	0.2	0.9	0.8	0.9	1.1	1.3	0.2	-0.5	-0.0	0.8	1.4	0.9	0.8	0.8	0.8	0.5
Mother’s age at death	0.7	0.9	4.0	-1.1	-0.9	-0.7	-1.0	-1.4	-1.0	-0.4	-0.6	-0.9	-0.8	-0.8	-1.4	-2.0	0.5	1.4	0.3	-0.8	-0.7	-1.0	-0.8	-0.7	-0.7	-0.4
Commuting to job workplace: Public transport	0.7	0.8	2.4	0.9	1.1	0.9	1.1	1.4	0.9	1.0	0.1	1.0	0.9	0.9	1.0	1.5	0.6	-0.1	-0.3	1.1	0.2	1.1	0.8	0.8	0.8	0.7
Impedance of whole body	0.7	3.5	22.4	1.6	1.1	1.5	2.4	2.7	1.6	0.2	-0.5	1.0	1.2	1.2	3.6	2.0	1.5	-4.7	-2.3	1.9	0.3	0.8	1.2	0.8	0.7	0.5
Major Depression (MDD)	0.6	0.7	3.2	-0.8	-0.9	-0.7	-1.8	-1.3	-0.4	-1.1	-0.9	-0.7	-0.3	-0.6	-0.6	-0.9	-0.3	1.1	0.9	-1.0	-0.9	-0.4	-0.4	-0.5	-0.4	-0.6
Ovarian Cancer	0.6	0.8	4.9	0.6	0.8	0.9	-0.2	0.6	0.8	1.3	1.0	0.6	0.5	0.6	0.3	1.1	0.3	0.3	-2.2	1.8	0.5	0.5	0.6	0.9	0.7	0.8
Body Mass Index (BMI) (2010)	0.6	0.9	6.4	-0.2	-0.4	-0.4	-1.8	-0.5	-0.2	-0.5	0.7	-0.0	0.1	-0.2	-1.6	-0.5	-0.6	2.5	1.4	-1.4	-1.1	0.2	-0.3	0.4	0.6	0.5
Fasting Glucose	0.6	0.8	5.0	0.2	-1.2	-0.3	-0.4	0.8	-0.6	-2.2	-0.9	-1.0	-0.3	-0.2	-0.3	0.0	-1.8	-1.1	0.3	-1.5	0.4	-0.5	-0.1	-0.3	-0.1	-0.4
Respiratory disease	0.6	1.3	5.3	0.9	1.4	0.9	-0.1	0.1	1.1	1.8	1.5	1.2	1.2	1.1	-0.1	0.8	0.9	2.3	-0.2	1.1	0.7	1.0	1.1	1.3	1.2	1.5
Severe depression (siblings)	0.6	0.7	4.6	0.1	0.2	0.4	-2.2	-0.8	0.1	0.7	0.9	0.1	0.3	0.2	-0.8	-0.6	0.4	2.1	0.6	-0.0	-0.8	0.6	0.4	0.6	0.6	0.7
Trunk fat percentage	0.6	2.4	6.1	-0.9	-2.1	-1.5	-0.1	-0.5	-1.3	-2.3	-2.1	-1.5	-1.3	-1.1	-1.7	-0.4	-2.0	0.9	1.9	-2.5	-2.2	-0.7	-1.4	-1.4	-1.0	-1.4
Maternal smoking around birth	0.6	0.8	4.8	-0.3	-1.4	-0.6	0.3	-0.2	-0.3	-1.6	-2.2	-0.9	-0.6	-0.6	0.2	-0.5	-0.4	-2.0	-0.7	-0.6	-0.3	-0.8	-0.6	-0.8	-0.7	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	3.3	-0.8	-1.6	-0.9	-0.4	-0.6	-1.2	-1.8	-1.8	-1.4	-1.2	-1.0	-0.7	-1.3	-0.4	-0.5	0.7	-1.5	-0.8	-1.2	-1.1	-1.1	-1.0	-1.1
Qualifications: None of the above	0.6	1.2	9.9	0.3	-0.3	-0.1	2.5	0.3	0.2	-0.3	-0.9	-0.3	-0.1	0.1	1.2	1.3	-0.5	-3.1	-2.0	0.7	0.7	-0.5	-0.1	-0.6	-0.7	-0.5
Arm fat percentage (right)	0.6	2.4	5.3	-1.1	-1.9	-1.6	0.6	-0.6	-1.5	-1.8	-2.0	-1.4	-1.5	-1.3	-2.0	-0.4	-2.1	1.3	1.8	-2.3	-1.8	-0.8	-1.5	-1.5	-1.1	-1.6
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	6.0	0.4	1.0	0.5	-1.6	0.3	0.2	0.6	1.1	0.8	0.5	0.4	-0.7	-0.3	0.8	2.4	1.7	-0.3	-0.5	1.1	0.6	0.8	1.0	0.9
Chronic bronchitis/emphysema (mother)	0.6	0.7	5.0	0.6	0.6	0.5	1.4	0.8	0.6	0.4	0.1	0.4	0.4	0.5	1.5	0.9	0.1	-2.2	-1.4	1.2	0.5	0.0	0.3	0.1	0.0	0.1
Qualifications: College or University degree	0.6	2.0	9.1	0.6	1.7	1.0	-1.8	0.1	0.8	1.8	2.2	1.4	1.1	0.9	0.0	0.3	1.1	3.0	2.2	0.8	0.5	1.6	1.2	1.5	1.5	1.2
Irritability	0.6	1.1	2.6	-1.3	-0.9	-1.1	-0.6	-1.3	-0.8	-0.8	-0.9	-1.0	-1.0	-1.4	-0.5	-1.6	-0.2	-0.8	-0.4	-0.2	0.5	-1.2	-1.1	-1.3	-1.4	-1.3
Ever had prostate specific antigen (PSA) test	0.6	0.6	3.7	0.4	0.6	0.7	0.3	0.6	0.3	0.5	0.7	0.9	0.4	0.6	0.2	-0.4	1.7	0.8	1.9	-0.2	1.0	0.7	0.5	0.9	0.9	0.8
Crohns Disease (2017)	0.5	1.1	8.6	0.4	0.1	0.5	1.2	0.4	0.6	-0.2	-0.0	-0.0	0.2	0.2	2.2	1.2	-0.3	-2.9	-2.5	1.3	0.9	-0.1	0.2	0.1	-0.2	-0.1
Crohns Disease (2012)	0.5	0.8	6.1	0.4	0.0	0.4	2.0	0.9	0.2	-0.3	-0.5	-0.1	0.0	0.2	1.5	1.0	-0.8	-2.5	-1.2	0.5	0.0	-0.5	0.1	0.1	-0.2	-0.1
Ever had hysterectomy (womb removed)	0.5	0.5	3.5	-0.9	-0.6	-0.8	-0.6	-1.9	-0.5	-0.2	-0.1	-0.5	-0.5	-0.7	-0.4	-0.7	-0.1	0.5	-1.1	0.0	1.0	-0.9	-0.5	-0.4	-0.6	-0.5
Townsend deprivation index at recruitment	0.5	0.7	4.0	0.3	0.3	0.4	2.0	1.0	0.7	0.3	-0.6	0.6	0.6	0.3	1.1	0.7	0.3	-1.8	-1.3	0.7	0.2	0.5	0.5	0.2	0.2	0.1
Age when periods started (menarche)	0.5	1.2	6.7	0.9	0.9	0.9	2.6	1.8	1.0	0.4	0.1	1.2	1.0	0.8	1.4	0.9	0.6	-2.0	-1.0	0.9	0.3	0.5	1.0	0.7	0.6	0.7
Alcohol usually taken with meals	0.5	0.8	4.9	1.2	-0.1	0.8	-0.7	2.2	0.7	-1.4	0.2	0.3	0.8	0.7	0.1	0.9	-0.8	-1.1	-0.4	-0.7	-0.7	0.4	0.7	0.8	1.0	0.9
Had menopause	0.5	0.6	2.1	-0.4	-0.9	-0.3	-0.7	-1.0	-0.4	-0.6	-1.3	-0.9	-0.6	-0.4	0.1	-0.9	0.1	-1.2	-1.5	0.1	-0.3	-1.0	-0.6	-0.6	-0.8	-0.7
Pain all over the body in last month	0.5	0.5	5.9	0.3	0.0	0.4	0.3	1.0	0.4	-0.3	0.4	0.1	0.2	0.2	0.1	0.7	-0.6	-0.8	-2.4	0.4	1.7	-0.1	0.2	0.4	0.2	0.2
Number of live births	0.5	0.7	2.9	-0.5	-1.1	-0.5	0.3	-0.2	-0.5	-1.0	-1.7	-0.8	-0.7	-0.6	0.0	-0.8	0.4	-1.3	-1.0	-0.5	1.2	-1.1	-0.8	-0.8	-0.9	-0.9
Happiness	0.5	0.6	4.9	-0.6	-0.2	-0.6	-2.2	-0.6	-0.1	-0.4	-0.1	-0.3	-0.1	-0.5	-0.9	-0.6	-0.2	2.2	0.8	-0.5	0.7	0.2	-0.2	-0.1	0.0	-0.2
Mouth/teeth dental problems: Dentures	0.5	0.8	3.8	-0.3	-1.0	-0.8	0.2	0.1	-0.5	-1.5	-2.0	-0.9	-0.7	-0.7	0.4	0.2	-0.4	-1.9	-0.4	-0.9	-0.1	-0.6	-0.8	-1.1	-0.9	-1.2
Exposure to tobacco smoke at home	0.5	0.6	3.4	0.9	-0.3	0.5	1.1	1.5	0.6	-0.6	-0.6	0.1	0.4	0.6	1.1	1.0	-0.6	-1.9	-0.5	-0.1	-0.6	0.3	0.4	0.3	0.4	0.6
Tense / ‘highly strung’	0.5	0.9	5.9	-0.8	0.7	-0.6	-0.2	-1.1	-0.2	1.3	0.8	0.4	-0.1	-0.6	-0.5	-0.6	0.7	2.4	1.1	0.7	2.2	0.6	-0.0	-0.1	-0.2	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	5.6	-0.9	-0.4	-1.1	-0.9	-1.1	-0.7	-0.1	0.1	-0.6	-0.6	-0.9	-1.5	-0.4	-1.1	2.4	0.7	-0.8	-1.0	-0.3	-0.6	-0.5	-0.4	-0.6
Peak expiratory flow (PEF)	0.5	1.2	2.8	1.2	1.2	1.1	-1.1	0.5	1.0	0.9	1.7	1.1	1.1	1.2	1.1	1.2	0.3	0.7	1.1	0.7	-0.3	1.5	1.1	1.3	1.4	1.3
Average weekly champagne plus white wine intake	0.5	0.7	2.5	1.1	0.5	0.9	-0.5	1.1	0.9	-0.3	0.3	0.4	0.7	0.8	1.1	1.3	-0.4	-1.6	-0.7	0.6	-0.5	0.6	0.7	0.7	0.8	0.7
Hearing aid user	0.5	0.6	5.9	0.4	-0.4	0.4	1.0	0.3	0.2	-0.4	-0.2	-0.2	0.0	0.2	1.2	0.2	-0.1	-2.4	-1.7	0.6	0.1	-0.6	0.1	0.1	-0.1	0.2
Financial situation satisfaction	0.5	0.6	2.8	-0.7	-0.6	-0.9	1.2	0.7	-0.4	-0.8	-0.6	-0.4	-0.6	-0.8	-0.1	-0.2	-1.7	-1.0	-0.5	-0.5	-1.1	-0.5	-0.7	-0.8	-0.8	-0.9
Alcohol drinker status: Never	0.5	0.6	3.1	-0.2	-0.7	-0.6	-0.2	1.1	-0.6	-1.2	-0.9	-0.6	-0.5	-0.5	-1.0	0.2	-1.8	0.4	0.6	-1.4	-1.2	-0.1	-0.5	-0.4	-0.2	-0.5
Number of operations (self-reported)	0.5	0.8	6.2	0.7	0.1	0.6	-0.7	2.5	0.4	-0.8	-1.7	0.6	0.6	0.6	0.0	0.3	0.2	0.6	0.6	-0.7	-1.1	0.9	0.5	0.7	1.0	0.5
Commuting to job workplace: Cycle	0.5	0.6	4.7	0.1	1.0	0.4	-0.2	0.6	0.1	1.3	1.3	0.8	0.3	0.2	-0.6	0.2	0.5	2.2	0.8	0.3	-0.4	0.8	0.3	0.7	0.8	0.6
Bipolar Disorder (2018)	0.4	0.6	3.0	-0.6	0.7	0.1	0.6	-1.7	-0.1	1.6	0.5	0.4	-0.3	-0.2	-0.2	-0.5	1.5	0.7	-0.4	1.2	0.4	-0.1	-0.4	-0.3	-0.5	-0.4
Schizophrenia (2018)	0.4	0.8	5.8	-0.4	-0.4	-0.6	-0.1	-0.0	-0.6	-0.2	-1.3	-0.3	-0.3	-0.5	-0.9	-0.3	-0.5	1.9	2.4	-1.2	-1.8	0.2	-0.4	-0.5	-0.1	-0.6
Alzheimer’s Disease (including proxy)	0.4	0.5	3.4	-0.4	0.5	0.0	-0.2	-1.6	0.1	1.1	1.5	0.2	-0.0	0.0	-0.2	-0.8	0.8	0.3	-0.2	1.1	1.8	-0.2	-0.1	0.1	-0.3	0.1
HDL Cholesterol	0.4	0.7	3.1	0.5	0.7	0.7	-1.4	0.3	0.3	0.7	1.5	0.7	0.6	0.7	-0.7	-0.2	0.5	1.8	0.6	-0.0	-0.2	0.8	0.7	0.9	1.0	0.9
Schizophrenia (2014)	0.4	0.8	2.7	-1.0	-0.6	-0.8	0.2	-1.1	-0.9	-0.1	-1.6	-0.8	-0.8	-0.9	-0.8	-0.9	0.2	0.9	1.6	-0.8	0.0	-0.5	-0.8	-0.8	-0.8	-1.0
Impedance of leg (right)	0.4	1.8	18.9	-0.3	-1.1	-0.4	0.8	1.0	-0.4	-1.8	-2.0	-1.1	-0.7	-0.8	1.4	0.1	-0.3	-4.4	-1.5	-0.3	-0.5	-1.1	-0.7	-1.1	-1.1	-1.3
Supplements: Glucosamine	0.4	0.5	2.6	0.0	-1.3	-0.1	-0.7	0.2	-0.3	-1.6	-0.5	-1.0	-0.4	-0.1	-0.5	-0.3	-1.0	-1.0	-0.9	-0.9	-0.7	-1.1	-0.5	-0.3	-0.3	-0.0
Number of incorrect matches in round	0.4	0.7	4.9	-0.2	1.1	-0.2	2.2	-0.8	0.1	1.9	1.2	0.6	-0.0	-0.0	0.2	0.9	0.6	0.0	-0.4	1.5	0.8	0.2	0.0	-0.1	-0.4	-0.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.1	-0.7	0.0	-0.7	-0.0	-1.1	-0.6	0.8	1.3	-0.1	-0.5	-0.4	-1.4	-0.6	-0.1	1.4	-0.4	0.1	-0.9	-0.7	-0.5	-0.2	-0.4	0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	4.6	0.7	1.3	0.8	-1.0	-0.2	0.7	1.5	1.9	1.1	0.9	0.9	0.4	1.0	0.5	2.2	1.6	0.6	-0.2	1.5	0.9	1.1	1.3	1.0
Prospective memory result	0.4	0.5	3.4	-0.8	-0.3	-0.6	-0.5	-1.8	-0.5	0.5	-0.2	-0.5	-0.7	-0.6	-0.5	-0.8	0.5	0.3	-0.3	0.4	0.3	-0.6	-0.8	-0.6	-0.8	-0.6
Lung cancer (father)	0.4	0.4	1.2	-0.7	-0.3	-0.5	-0.2	-0.6	-0.7	-0.1	-0.3	-0.4	-0.7	-0.6	-1.1	-0.8	0.1	0.7	-1.0	-0.3	0.5	-1.1	-0.8	-0.6	-0.7	-0.6
Pulse wave reflection index	0.4	0.5	2.0	0.8	0.4	0.5	0.7	1.2	0.8	-0.1	0.0	0.5	0.6	0.5	1.3	1.2	-0.2	-1.4	-0.7	0.6	0.1	0.5	0.5	0.4	0.5	0.4
Worry too long after embarrassment	0.4	0.6	3.0	-0.9	-0.3	-0.6	-0.6	-1.3	-0.6	0.2	0.3	-0.6	-0.8	-0.8	-0.1	-0.9	0.3	-0.5	-1.7	0.7	0.4	-1.2	-0.7	-0.6	-1.0	-0.5
Emphysema/chronic bronchitis	0.4	0.5	2.6	-0.4	-0.7	-0.3	-0.7	-1.0	-0.4	-0.7	-1.6	-0.7	-0.5	-0.3	-0.1	-0.6	1.2	-0.6	0.4	-0.6	0.0	-0.5	-0.4	-0.7	-0.6	-0.6
Medication: Seretide 50 evohaler	0.4	0.5	1.1	0.9	0.6	0.9	-0.5	0.7	0.9	0.1	-0.1	0.6	0.7	0.9	1.0	0.5	0.7	-1.1	-0.2	0.8	0.0	0.6	0.8	0.8	0.8	0.7
Overall health rating	0.4	0.9	3.1	-1.0	-1.2	-1.1	-1.1	-1.1	-0.7	-1.4	-1.8	-1.1	-0.7	-1.0	-0.3	-0.9	-0.3	0.2	0.5	-0.9	0.3	-0.4	-0.8	-1.1	-0.9	-1.3
Age at last live birth	0.4	0.6	1.4	1.0	0.6	0.9	0.6	1.0	0.8	0.2	0.9	0.9	1.0	0.9	0.3	1.0	-0.4	0.1	0.3	0.2	-0.0	1.2	1.0	0.9	1.0	0.9
Commuting to job workplace: Car/motor vehicle	0.4	0.5	2.0	-0.1	-1.1	-0.4	-1.1	-0.4	-0.3	-1.4	-0.8	-1.0	-0.4	-0.4	-0.4	-0.4	-1.2	-0.7	-0.3	-1.0	-0.9	-0.7	-0.3	-0.5	-0.4	-0.3
Arm fat percentage (left)	0.4	1.6	3.6	-0.9	-1.5	-1.4	0.7	-0.6	-1.2	-1.4	-1.7	-1.0	-1.1	-0.9	-1.7	-0.1	-1.8	1.4	1.7	-1.9	-1.8	-0.4	-1.2	-1.2	-0.8	-1.2
Qualifications: nursing, teaching	0.4	0.7	3.8	-0.4	0.3	0.3	-2.0	-0.6	-0.1	0.8	0.7	0.2	0.0	-0.1	-0.7	-1.8	1.4	1.8	0.1	0.1	-0.1	-0.0	0.1	0.5	0.3	0.5
Breast cancer (self-reported)	0.4	0.5	2.4	-0.4	-0.6	-0.4	-0.8	-0.6	-0.4	-0.5	-0.9	-0.4	-0.1	-0.3	-1.2	-0.7	-0.7	1.6	0.8	-1.3	-1.1	0.0	-0.1	-0.4	-0.2	-0.2
Bipolar Disorder or Schizophrenia	0.3	0.6	3.6	-0.7	0.2	-0.4	0.3	-1.1	-0.5	0.9	-0.7	0.0	-0.4	-0.5	-0.8	-0.6	0.6	1.9	1.6	-0.2	-1.2	0.1	-0.6	-0.6	-0.4	-0.8
Ulcerative Colitis	0.3	0.4	2.4	0.7	-0.1	0.4	0.2	0.9	0.6	-0.4	-0.7	0.0	0.4	0.4	1.4	1.0	-0.4	-1.5	-0.2	0.3	0.0	0.0	0.3	0.4	0.4	0.3
Medication: Co-codamol	0.3	0.3	1.2	-0.6	-0.4	-0.6	-0.8	-0.5	-0.6	-0.3	-0.5	-0.5	-0.5	-0.5	-0.7	-0.4	-0.1	0.7	1.1	-0.7	-0.7	-0.1	-0.4	-0.6	-0.3	-0.6
Qualifications: CSEs or equivalent	0.3	0.4	1.9	0.6	-0.6	0.0	-0.1	1.3	0.2	-1.4	-0.3	-0.0	0.3	0.2	-0.1	0.4	-1.3	-0.6	0.0	-1.2	-1.0	0.3	0.3	0.1	0.4	0.4
Serious illness, injury or assault to yourself	0.3	0.4	0.9	0.6	0.6	0.5	0.4	0.7	0.8	0.5	0.1	0.6	0.8	0.5	1.0	0.8	0.5	-0.2	-0.7	0.7	0.9	0.7	0.7	0.5	0.6	0.4
Impedance of leg (left)	0.3	1.4	16.1	0.3	-0.6	0.3	0.8	1.4	0.2	-1.4	-1.2	-0.5	-0.1	-0.1	1.8	0.4	0.0	-4.0	-2.0	0.1	0.1	-0.6	-0.1	-0.4	-0.4	-0.5
Financial difficulties in last 2 years	0.3	0.3	0.9	-1.0	-0.3	-1.0	0.2	-0.7	-0.6	-0.4	0.2	-0.2	-0.7	-1.0	-0.8	-0.6	-0.3	-0.1	0.2	-0.3	-0.4	-0.6	-0.7	-0.7	-0.8	-0.4
Noisy workplace	0.3	0.4	1.8	-0.1	-0.6	-0.4	0.1	0.8	-0.4	-1.2	-1.4	-0.4	-0.3	-0.3	-0.4	0.5	-0.9	-0.7	0.3	-1.1	-0.2	-0.2	-0.3	-0.7	-0.4	-0.5
Asthma	0.3	0.5	5.3	-0.2	0.6	0.1	-1.0	-0.7	0.1	1.2	0.9	0.5	0.2	0.1	-0.9	-0.3	0.5	2.3	0.3	0.3	0.1	0.4	0.3	0.4	0.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	4.6	0.3	1.3	0.6	-1.2	-0.2	0.3	1.6	1.8	1.0	0.6	0.6	0.2	0.5	0.9	2.2	2.0	0.6	-0.2	1.4	0.6	0.8	1.0	0.7
Hair/balding pattern: Pattern 4	0.3	0.7	3.4	1.0	0.6	0.8	1.8	1.3	0.6	0.4	-0.3	0.8	0.6	0.9	1.1	1.8	-0.2	-0.4	-0.1	0.7	0.3	0.6	0.5	0.7	0.7	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.6	0.1	0.6	0.2	1.6	0.4	0.4	1.1	0.6	0.6	0.3	0.1	0.2	0.4	0.9	-0.5	-1.3	0.9	0.7	0.1	0.2	0.2	0.1	0.4
Age at first live birth	0.3	0.6	1.4	0.7	0.7	0.8	-1.0	0.2	0.6	0.5	1.2	0.8	0.8	0.8	0.0	0.3	-0.3	1.1	0.8	0.2	-1.0	1.1	0.8	0.9	1.0	0.9
Shortness of breath walking on level ground	0.3	0.3	1.1	-0.7	-0.3	-0.6	-0.0	-1.1	-0.6	0.1	-0.9	-0.5	-0.6	-0.6	-0.2	-0.5	0.5	0.1	0.7	-0.1	0.1	-0.2	-0.6	-0.7	-0.7	-0.9
Pulse rate, automated reading	0.3	1.0	2.8	1.2	1.3	1.4	-0.4	0.1	1.0	1.0	0.2	1.1	0.9	1.4	1.2	1.2	1.7	-0.0	0.5	1.0	-0.6	1.1	1.0	1.1	1.1	0.8
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.9	-0.3	-0.7	-0.3	-0.5	-1.4	-0.6	-0.4	-0.5	-0.8	-0.7	-0.3	-0.4	-0.6	0.1	-0.1	-0.1	-0.2	-0.5	-1.0	-0.8	-0.5	-0.7	-0.6
Supplements: Vitamin C	0.3	0.3	2.2	0.4	0.5	0.3	-0.3	-0.1	0.2	0.5	0.3	0.6	0.3	0.5	-0.3	0.4	0.5	1.2	1.5	-0.0	-0.5	0.5	0.3	0.6	0.6	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	3.6	-0.9	-0.5	-0.8	-0.8	-0.8	-0.7	-0.2	0.8	-0.5	-0.6	-0.7	-1.2	-0.8	-0.7	1.9	0.8	-0.6	0.1	-0.4	-0.7	-0.5	-0.5	-0.5
Average weekly red wine intake	0.3	0.4	1.2	-0.6	-0.4	-0.5	-0.7	0.4	-0.7	-0.3	-0.9	-0.3	-0.6	-0.7	-1.1	-0.7	0.2	1.0	-0.1	-0.7	-0.8	-0.3	-0.7	-0.5	-0.3	-0.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	-0.6	-0.6	-0.5	-0.0	-0.5	-0.5	-0.6	-0.5	-0.5	-0.7	-0.7	-0.6	-0.7	-0.1	-0.9	-1.0	-0.2	-0.4	-1.0	-0.8	-0.6	-0.8	-0.4
Commuting to job workplace: Walk	0.3	0.3	3.7	0.2	-0.1	0.0	-0.6	0.1	-0.0	-0.1	-0.1	0.1	0.2	0.2	-0.2	-0.4	0.1	1.0	1.9	-0.8	0.3	0.7	0.1	0.2	0.4	0.1
Asthma (self-reported)	0.3	0.5	5.1	-0.1	0.8	0.2	-0.9	-0.7	0.2	1.3	0.9	0.6	0.3	0.1	-0.8	-0.1	0.7	2.3	0.2	0.5	0.1	0.4	0.3	0.5	0.4	0.6
Wears glasses or contact lenses	0.3	0.3	1.7	0.7	0.2	0.6	-0.8	0.5	0.4	-0.2	-0.4	0.3	0.5	0.8	0.5	0.4	0.8	0.0	1.3	-0.1	-0.0	0.7	0.5	0.5	0.7	0.4
Medication: Paracetamol	0.3	0.5	1.9	-0.4	-0.7	-0.6	-0.3	0.4	-0.6	-1.4	-1.0	-0.5	-0.7	-0.6	-0.5	-0.3	-0.3	-0.7	0.8	-1.2	-0.2	-0.6	-0.7	-0.6	-0.5	-0.6
Unable to work because of sickness or disability	0.3	0.4	2.2	0.1	1.1	0.2	0.6	0.1	0.4	1.5	0.3	0.8	0.4	0.2	0.5	0.8	1.1	0.7	0.5	1.0	0.4	1.1	0.3	0.3	0.4	0.0
Myopia	0.3	0.4	3.6	0.4	0.4	0.6	0.9	-0.4	0.4	0.5	-0.1	0.5	0.4	0.5	1.1	-0.2	1.9	-0.7	0.1	0.5	1.1	0.4	0.3	0.3	0.2	0.2
Heart disease (siblings)	0.3	0.4	1.3	0.9	-0.0	0.6	0.7	0.8	0.3	-0.3	-0.2	0.0	0.2	0.7	1.0	1.2	-0.9	-1.1	-0.0	-0.1	-0.6	0.3	0.3	0.2	0.5	0.1
Neuroticism (2016)	0.2	0.2	2.5	-0.5	-0.4	-0.2	0.1	-0.4	-0.1	-0.3	-0.5	-0.4	-0.2	-0.3	-0.2	-0.6	0.3	-0.7	-1.6	0.4	0.1	-0.5	0.0	-0.4	-0.6	-0.3
Average weekly spirits intake	0.2	0.2	1.0	0.4	-0.0	0.4	-0.4	-0.0	0.5	0.1	0.4	0.0	0.4	0.4	0.5	0.6	0.4	-0.0	-0.7	0.5	1.0	0.1	0.4	0.6	0.5	0.6
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.9	-0.1	-0.3	-0.3	0.9	0.6	-0.3	-0.4	-0.3	-0.4	-0.4	-0.5	-0.0	0.5	-0.8	-0.9	-0.9	-0.1	-0.0	-0.5	-0.4	-0.3	-0.4	-0.4
Diabetes (mother)	0.2	0.2	1.5	0.2	-0.0	0.1	-0.2	0.8	0.2	-0.3	0.6	0.2	0.2	0.2	-0.4	0.2	-0.9	1.2	-0.1	-0.2	0.3	0.5	0.2	0.4	0.5	0.2
Hand grip strength (right)	0.2	0.5	1.4	0.8	0.5	0.9	-1.2	0.7	0.8	0.2	1.1	0.6	0.8	0.8	0.2	0.4	0.1	0.6	-0.7	0.6	0.4	0.6	0.8	0.9	0.9	1.1
Nervous feelings	0.2	0.4	1.1	-1.0	0.5	-0.8	0.3	-1.0	-0.7	0.7	-0.1	0.1	-0.8	-0.9	-0.4	-0.6	1.0	0.1	0.6	0.4	0.3	-0.5	-0.7	-0.7	-0.8	-0.8
Time employed in main current job	0.2	0.2	1.5	-0.0	-0.2	-0.3	1.2	0.5	-0.4	-0.2	-0.1	-0.0	-0.2	-0.1	-0.2	0.1	-0.2	-0.0	1.0	-1.0	-1.0	-0.2	-0.4	-0.3	-0.0	-0.1
Hair/balding pattern: Pattern 3	0.2	0.2	1.7	0.2	0.2	0.2	-0.7	-0.3	0.1	0.2	0.5	0.2	0.3	0.3	0.1	-0.1	0.8	0.5	1.3	-0.3	-0.7	0.5	0.3	0.2	0.3	0.6
Depression (self-reported)	0.2	0.3	1.7	-0.3	-0.4	-0.4	-1.3	-0.5	-0.4	-0.4	0.0	-0.5	-0.3	-0.4	-0.9	-0.5	-0.6	0.9	0.5	-0.8	-0.5	-0.2	-0.2	-0.3	-0.1	-0.1
Length of working week for main job	0.2	0.2	1.8	-0.0	0.0	0.1	1.2	-0.5	0.2	0.7	0.3	0.3	0.4	0.2	0.2	-0.3	0.5	0.5	0.0	0.1	1.3	0.2	0.5	0.2	0.1	0.1
Medication: Paracetamol	0.2	0.4	2.2	0.3	-0.5	-0.1	-0.2	1.2	-0.1	-1.5	-0.5	-0.1	-0.2	-0.0	-0.2	0.4	-0.9	-0.8	1.0	-1.2	0.1	-0.0	-0.2	-0.1	0.2	-0.1
Glaucoma (self-reported)	0.2	0.3	0.8	-0.3	-0.7	-0.3	-0.6	-0.5	-0.5	-0.8	-0.9	-0.7	-0.5	-0.3	-0.4	-0.4	-0.2	-0.4	-0.2	-0.6	-0.3	-0.6	-0.5	-0.5	-0.4	-0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.8	-0.7	-0.3	-0.5	-0.7	-1.3	-0.3	-0.0	-0.3	-0.3	-0.4	-0.5	-0.3	-1.1	0.6	0.1	0.5	0.1	-0.3	-0.5	-0.4	-0.4	-0.5	-0.2
Forced vital capacity (FVC), Best measure	0.2	0.7	2.2	0.3	1.3	0.6	-0.7	-0.2	0.5	1.5	1.5	0.9	0.6	0.6	0.8	0.6	1.0	1.1	1.0	1.1	0.2	1.1	0.6	0.7	0.7	0.5
Eye problems/disorders: None of the above	0.2	0.3	0.9	0.4	0.6	0.6	0.6	-0.1	0.5	0.6	0.9	0.8	0.6	0.6	-0.1	-0.1	0.7	0.6	0.1	0.6	0.2	0.6	0.6	0.6	0.4	0.5
Number of full sisters	0.2	0.3	1.1	-0.6	-0.3	-0.5	0.5	0.2	-0.6	-0.2	-0.0	-0.1	-0.4	-0.5	-0.8	-0.6	-0.5	0.9	0.7	-1.1	0.6	-0.2	-0.4	-0.4	-0.2	-0.5
Chest pain or discomfort	0.2	0.4	1.2	-0.8	-0.5	-0.7	-0.3	-0.3	-0.4	-0.7	-1.1	-0.3	-0.6	-0.8	-0.3	-0.9	0.1	-0.4	0.4	-0.3	-0.0	-0.3	-0.6	-0.7	-0.7	-1.0
Family relationship satisfaction	0.2	0.2	2.7	-0.2	0.3	-0.2	-0.6	0.1	0.1	0.2	0.4	0.3	0.2	-0.2	-0.8	-0.2	-0.3	1.6	-0.2	0.1	0.7	0.3	0.1	0.2	0.2	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	3.0	0.2	-0.2	0.1	0.2	0.3	0.3	-0.7	-0.4	0.0	0.2	0.1	0.3	0.2	-0.2	-1.7	-1.2	-0.0	-0.6	-0.0	0.1	-0.1	-0.1	0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	3.1	0.0	-0.1	0.0	1.8	0.3	0.0	-0.2	-0.1	0.2	-0.1	-0.1	0.2	-0.1	0.1	-1.4	-0.9	0.2	-0.2	-0.4	-0.2	-0.2	-0.4	0.0
Alzheimer’s Disease (in father)	0.1	0.1	0.5	-0.2	-0.1	-0.1	0.7	-0.4	-0.3	0.2	-0.4	-0.3	-0.4	-0.2	-0.1	-0.2	0.5	-0.7	0.2	0.1	0.2	-0.3	-0.4	-0.5	-0.5	-0.4
Age at First Birth	0.1	0.2	1.3	0.2	-0.7	0.0	0.0	0.4	-0.0	-0.9	-0.7	-0.3	0.0	0.1	-0.2	0.3	-0.8	0.2	-0.2	-0.2	-1.2	-0.1	0.1	0.1	0.2	0.2
Heel T-Score	0.1	1.0	2.5	1.1	0.8	1.1	1.3	1.3	1.1	0.9	0.5	0.8	1.0	1.1	1.6	1.2	0.2	-0.7	-0.1	1.0	0.1	1.1	1.1	1.0	0.9	0.8
Hand grip strength (left)	0.1	0.3	2.4	0.3	-0.2	0.2	-1.6	0.1	0.3	-0.4	0.4	-0.1	0.3	0.3	-0.3	0.2	-0.7	0.6	-0.0	-0.1	-0.9	0.1	0.3	0.4	0.5	0.7
Average weekly fortified wine intake	0.1	0.1	0.5	0.1	-0.1	0.3	-0.1	-0.0	0.2	-0.2	-0.5	0.3	0.2	0.1	-0.2	-0.7	0.7	0.0	-0.6	-0.2	0.4	0.2	0.1	0.2	0.2	0.2
Sitting height	0.1	1.0	6.7	0.3	0.3	0.5	-2.6	-0.5	0.7	-0.0	1.2	0.5	0.9	0.6	-0.0	-0.2	0.1	2.4	1.5	0.0	0.0	1.4	0.9	0.9	1.0	0.8
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	-0.1	0.1	0.1	0.3	0.5	-0.1	0.2	-0.3	0.2	-0.1	-0.0	-0.2	-0.6	0.2	-0.2	0.0	-0.3	-0.7	0.0	-0.0	-0.1	-0.0	-0.1
Forced vital capacity (FVC)	0.1	0.6	2.2	0.2	0.8	0.4	-1.0	-0.8	0.5	1.3	1.5	0.6	0.5	0.5	0.5	0.5	0.5	1.2	0.7	0.9	-0.0	0.7	0.5	0.6	0.6	0.5
Wheeze or whistling in the chest in last year	0.1	0.2	1.0	0.7	-0.2	0.5	-0.4	0.4	0.6	-0.3	0.2	0.2	0.5	0.6	-0.0	0.5	-1.0	-0.0	-0.7	-0.1	-0.7	0.6	0.5	0.4	0.6	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	1.1	-0.2	0.1	-0.3	1.0	0.3	-0.1	0.4	0.3	0.2	-0.1	-0.2	0.0	0.6	-0.4	-0.1	0.2	0.1	0.6	0.1	-0.1	-0.1	-0.2	-0.3
Mineral and other dietary supplements	0.1	0.2	1.5	-0.2	0.1	-0.2	-1.1	-0.3	-0.1	0.2	-0.5	-0.1	0.1	-0.1	-0.1	-0.0	0.1	1.2	0.8	-0.2	-0.4	0.4	0.1	-0.1	0.2	-0.2
Osteoarthritis (self-reported)	0.1	0.2	1.0	0.5	-0.0	0.4	0.3	0.6	0.4	-0.4	0.0	0.1	0.2	0.5	0.3	-0.0	0.3	-0.8	-0.1	-0.1	1.0	-0.1	0.2	0.3	0.3	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.5	0.1	0.8	0.4	-0.6	-0.4	0.1	0.8	0.8	0.5	0.1	0.3	0.2	0.1	1.2	0.6	0.9	0.6	0.5	0.3	0.1	0.4	0.4	0.3
Eye problems/disorders: Glaucoma	0.1	0.1	0.9	-0.1	-0.2	-0.0	-0.1	-0.4	-0.2	-0.1	-0.4	-0.4	-0.4	-0.1	-0.0	0.2	-0.1	-0.8	-1.0	0.2	0.4	-0.6	-0.4	-0.4	-0.4	-0.2
Medication: Atorvastatin	0.1	0.1	0.4	-0.1	-0.4	-0.1	0.0	0.1	-0.1	-0.4	-0.5	-0.2	-0.2	-0.1	0.4	-0.2	0.4	-0.6	-0.0	-0.2	0.0	-0.3	-0.2	-0.1	-0.1	-0.2
Basal cell carcinoma (self-reported)	0.1	0.2	0.9	-0.4	-0.1	-0.1	-0.4	-0.8	0.0	0.3	-0.1	0.0	0.1	-0.1	-0.1	-0.7	1.0	0.5	-0.8	0.2	0.1	-0.4	-0.0	0.1	-0.0	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ALDH2

Models

Trait associations