TWAS hub - MMAB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1220	0.0330	3.4e-08	0.091	0.066	0.083	0.052	0.021	3.3e-11	1.9e-08	2.9e-10	6.2e-07	1.3e-03
2	GTEx	Adipose Visceral Omentum	0.0970	0.0430	6.8e-03	-0.005	NA	-0.005	NA	-0.001	8.5e-01	NA	9.5e-01	NA	3.8e-01
3	GTEx	Brain Cerebellar Hemisphere	0.3140	0.0910	7.9e-04	0.270	NA	0.230	NA	0.242	1.3e-07	NA	1.3e-06	NA	6.6e-07
4	GTEx	Brain Nucleus accumbens basal ganglia	0.3970	0.1050	7.6e-05	0.243	NA	0.285	NA	0.277	3.6e-07	NA	2.5e-08	NA	4.4e-08
5	GTEx	Cells Transformed fibroblasts	0.0700	0.0300	1.6e-03	0.058	NA	0.053	NA	0.051	3.9e-05	NA	7.3e-05	NA	1.1e-04
6	GTEx	Colon Transverse	0.0780	0.0380	8.6e-03	0.069	NA	0.020	NA	0.052	3.6e-04	NA	3.6e-02	NA	1.7e-03
7	GTEx	Muscle Skeletal	0.0601	0.0243	5.2e-04	0.041	NA	0.036	NA	0.047	5.9e-05	NA	1.6e-04	NA	1.9e-05
8	GTEx	Thyroid	0.0670	0.0310	3.2e-03	0.005	NA	0.023	NA	0.024	1.3e-01	NA	6.9e-03	NA	5.4e-03
9	TCGA	Breast Invasive Carcinoma	0.0309	0.0184	7.0e-05	0.010	0.025	0.023	NA	0.018	3.3e-03	6.5e-06	1.3e-05	NA	9.4e-05
10	TCGA	Cervical Squamous Cell Carcinoma	0.0490	0.0310	7.9e-03	0.012	0.015	0.005	NA	0.015	7.8e-02	5.8e-02	1.7e-01	NA	6.1e-02
11	TCGA	Colon Adenocarcinoma	0.1210	0.0830	5.0e-03	0.068	0.005	0.054	NA	0.068	9.5e-05	1.5e-01	4.3e-04	NA	8.6e-05
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0273	0.0165	2.3e-03	0.016	0.020	0.011	NA	0.008	6.2e-03	2.2e-03	2.1e-02	NA	3.5e-02
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0369	0.0225	4.6e-03	0.025	0.016	0.008	NA	0.011	7.4e-04	5.2e-03	4.2e-02	NA	1.9e-02
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0880	0.0430	6.7e-05	0.049	0.092	0.076	NA	0.073	8.9e-04	6.3e-06	3.9e-05	NA	5.5e-05
15	TCGA	Lung Adenocarcinoma	0.0280	0.0190	5.1e-03	0.023	0.019	0.010	NA	0.012	8.3e-04	2.4e-03	2.1e-02	NA	1.2e-02
16	TCGA	Lung Squamous Cell Carcinoma	0.0749	0.0644	4.6e-03	0.004	0.015	0.005	NA	0.011	1.1e-01	6.6e-03	7.1e-02	NA	1.9e-02
17	TCGA	Ovarian Serous Cystadenocarcinoma	0.0660	0.0490	5.1e-03	0.015	0.029	0.017	NA	0.017	3.1e-02	4.5e-03	2.5e-02	NA	2.5e-02
18	TCGA	Prostate Adenocarcinoma	0.0587	0.0275	2.4e-06	0.058	0.061	0.057	NA	0.061	1.2e-06	5.4e-07	1.2e-06	NA	5.4e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
HDL Cholesterol	21.5	35.9	58.8	-7.3	-7.5	-5.5	-6.5	-6.3	-7.6	-3.8	-6.7	-5.5	-4.7	-2.9	-7.1	-6.6	-6.3	-3.4	-5.2	-3.9	-7.7
Frequency of tiredness / lethargy in last 2 weeks	18.2	29.6	42.7	-6.3	-5.4	-2.5	-3.4	-6.5	-6.2	-4.8	-6.5	-6.0	-5.5	-3.2	-6.3	-6.2	-6.3	-5.4	-5.3	-5.2	-4.9
Neuroticism (Nagel 2018)	15.2	35.8	62.6	-7.1	-6.0	-3.5	-3.5	-7.9	-6.7	-5.9	-7.4	-6.0	-6.2	-2.9	-7.3	-7.0	-6.1	-4.8	-5.4	-5.5	-5.6
Frequency of tenseness / restlessness in last 2 weeks	14.1	22.0	30.4	-5.2	-4.2	-1.4	-2.5	-5.3	-5.0	-3.8	-5.5	-5.2	-5.4	-4.1	-5.4	-5.2	-5.5	-5.2	-4.6	-4.9	-3.5
Neuroticism	13.6	32.9	49.4	-6.5	-5.6	-2.9	-2.9	-7.0	-6.4	-5.5	-6.5	-6.0	-6.2	-3.0	-6.9	-6.6	-6.3	-5.2	-6.0	-5.7	-5.3
Worry (Nagel 2018)	10.6	22.4	39.8	-5.5	-4.5	-2.1	-2.1	-6.3	-5.2	-4.9	-5.6	-4.8	-5.3	-2.4	-6.0	-5.4	-4.8	-4.0	-4.7	-4.7	-4.1
Hearing difficulty/problems: Yes	10.2	15.6	29.6	-5.4	-3.9	-3.2	-3.2	-4.2	-5.0	-3.3	-4.4	-4.4	-3.2	-1.7	-4.8	-5.2	-3.7	-2.9	-2.3	-3.4	-4.5
Sensitivity / hurt feelings	9.9	17.0	28.0	-5.3	-5.3	-3.6	-2.2	-5.1	-5.2	-3.5	-4.9	-3.5	-3.7	-0.2	-5.1	-4.8	-4.0	-2.9	-3.6	-2.8	-4.8
Miserableness	9.9	17.1	27.8	-4.6	-4.0	-1.6	-2.8	-4.6	-4.6	-4.4	-4.3	-5.2	-4.5	-2.3	-5.1	-5.3	-3.9	-4.2	-2.6	-4.8	-3.4
Neuroticism score	9.6	19.9	32.3	-4.7	-4.7	-1.9	-1.9	-5.5	-5.0	-4.6	-5.0	-4.7	-5.1	-1.9	-5.7	-4.9	-4.9	-4.3	-4.4	-4.3	-4.1
Falls in the last year	9.6	13.0	22.5	-3.8	-4.7	-1.5	-3.2	-3.0	-4.1	-2.7	-4.1	-4.6	-3.8	-2.3	-3.9	-3.6	-4.6	-4.1	-2.5	-3.3	-3.4
Depressed Affect (Nagel 2018)	8.4	17.6	30.0	-4.6	-4.0	-2.2	-3.0	-5.5	-4.6	-4.4	-4.6	-4.5	-4.3	-3.2	-5.1	-5.0	-4.3	-3.6	-3.7	-4.1	-3.8
Pain experienced in last month	8.1	13.5	21.8	4.4	3.7	2.7	2.8	4.5	4.5	2.6	3.8	3.9	3.3	2.8	4.7	4.5	3.9	2.9	2.7	3.0	4.0
Worrier / anxious feelings	7.3	13.7	24.9	-3.9	-4.4	-2.0	-2.5	-4.6	-4.4	-3.9	-4.7	-3.9	-4.2	-1.0	-5.0	-4.0	-3.5	-2.8	-2.6	-3.2	-3.6
Mouth/teeth dental problems	7.2	11.0	22.7	3.6	4.3	1.6	2.4	3.6	4.0	3.2	3.4	3.5	3.5	0.4	4.8	3.5	3.5	3.0	2.4	2.5	3.8
Medication: Paracetamol	7.2	12.0	19.7	-3.6	-2.6	-0.2	-1.0	-3.8	-3.2	-4.2	-3.1	-4.0	-4.4	-3.2	-4.3	-4.0	-3.6	-4.2	-3.1	-4.3	-2.0
Irritability	6.8	11.4	21.9	-4.0	-3.6	-2.1	-2.7	-4.7	-3.8	-2.2	-4.6	-2.9	-3.2	-2.0	-3.8	-3.5	-3.8	-2.4	-3.8	-2.6	-3.4
Pain all over the body in last month	6.5	7.0	14.3	-2.7	-2.3	0.0	-1.1	-1.9	-2.5	-2.6	-2.4	-3.6	-3.2	-2.1	-2.5	-2.4	-3.8	-3.3	-3.3	-3.2	-2.0
Hearing difficulty/problems with background noise	6.2	10.0	18.0	-4.2	-3.4	-2.7	-1.3	-3.5	-4.1	-2.9	-3.4	-3.5	-2.7	-1.2	-4.0	-4.2	-3.0	-2.6	-1.8	-2.8	-3.6
Worry too long after embarrassment	6.2	10.5	20.7	-3.5	-3.9	-1.7	-1.2	-4.5	-3.7	-3.4	-4.5	-2.9	-3.3	0.2	-4.0	-3.3	-3.4	-2.6	-3.1	-2.4	-3.2
Mouth/teeth dental problems: Bleeding gums	5.7	7.4	14.1	-3.4	-3.5	-2.2	-1.8	-3.1	-3.5	-1.6	-2.8	-2.5	-2.5	0.3	-3.8	-3.2	-2.8	-1.8	-2.3	-1.9	-3.6
Mood swings	5.7	10.3	16.4	-3.8	-3.8	-2.8	-3.4	-3.8	-4.0	-2.5	-3.7	-3.1	-2.5	-1.8	-3.8	-3.9	-3.1	-2.3	-2.0	-2.3	-3.7
Townsend deprivation index at recruitment	5.4	7.6	14.9	-3.4	-3.1	-2.0	-1.4	-2.2	-3.4	-1.6	-2.6	-3.5	-2.9	-2.4	-3.4	-3.9	-2.6	-2.9	-0.9	-2.9	-2.6
Medication: Paracetamol	5.4	8.4	15.6	-2.7	-2.2	0.2	-0.4	-3.5	-2.6	-4.0	-2.6	-3.3	-3.7	-2.7	-3.7	-3.1	-3.0	-3.3	-2.8	-3.4	-1.6
Maternal smoking around birth	5.2	7.6	20.5	-3.2	-3.2	-4.5	-3.6	-2.0	-4.1	0.7	-2.5	-2.1	-1.2	-2.1	-2.9	-3.5	-2.2	-0.8	0.2	-0.7	-4.1
Medication: Ventolin 100micrograms inhaler	5.1	6.5	10.5	-2.5	-2.6	-0.8	-3.0	-2.9	-2.9	-1.7	-3.1	-3.0	-3.0	-1.8	-3.2	-2.7	-2.7	-2.3	-1.7	-2.4	-2.1
Schizophrenia (2018)	4.9	10.1	19.0	3.1	2.3	0.1	-0.3	3.6	2.6	3.3	4.0	3.6	4.4	2.7	3.7	3.6	3.2	3.6	3.6	4.1	1.4
Neck or shoulder pain in last month	4.9	6.9	12.8	-3.0	-1.9	-1.9	-2.0	-3.4	-3.0	-2.5	-2.9	-2.6	-2.5	-2.7	-3.6	-3.5	-2.3	-1.7	-1.8	-2.4	-2.5
Long-standing illness, disability or infirmity	4.9	7.4	15.4	-3.3	-3.7	-3.4	-3.1	-2.1	-3.7	-1.9	-1.9	-2.7	-1.7	-1.1	-3.0	-3.5	-2.5	-1.5	-1.4	-1.9	-3.9
Nervous feelings	4.7	8.7	15.1	-3.6	-2.6	-0.7	-0.5	-3.4	-3.1	-3.0	-3.2	-3.0	-3.6	-0.8	-3.9	-3.0	-3.4	-3.3	-3.4	-2.9	-2.5
Depression (Nagel 2018)	4.5	6.8	13.2	-3.0	-2.6	-2.5	-3.6	-3.6	-3.1	-1.7	-3.6	-2.2	-1.7	-1.4	-2.8	-2.8	-2.6	-1.2	-2.0	-1.5	-3.1
Chronic bronchitis/emphysema (father)	4.5	5.3	10.2	-2.0	-3.1	-0.2	-1.8	-1.3	-2.5	-1.9	-1.9	-2.9	-2.9	-1.4	-2.7	-2.1	-3.1	-3.2	-2.1	-2.5	-1.9
Allergy	4.5	10.4	17.9	3.6	2.4	-0.0	2.5	3.7	3.1	1.5	4.1	3.6	4.2	2.5	3.5	3.3	3.7	3.8	3.8	3.9	1.7
Medication for hormone replacement therapy	4.4	4.9	10.7	-2.3	-2.8	-0.5	-0.1	-2.0	-2.3	-1.9	-1.9	-2.3	-2.3	-1.6	-2.4	-2.0	-3.3	-2.7	-3.1	-2.0	-2.1
Peak expiratory flow (PEF)	4.4	10.2	19.8	3.4	4.4	0.2	2.2	3.0	3.2	3.5	3.3	3.5	4.1	0.9	3.6	2.7	3.9	3.9	3.2	3.1	2.3
Financial situation satisfaction	4.2	5.2	15.1	-3.3	-1.5	-3.2	-1.8	-2.6	-2.9	-1.5	-2.9	-2.0	-1.9	0.4	-2.5	-3.9	-1.0	-0.8	-0.8	-2.4	-2.3
Major Depression (MDD)	4.1	4.9	8.6	-2.5	-2.7	-2.2	-2.9	-2.5	-2.8	-0.3	-2.4	-1.8	-1.6	-2.4	-2.5	-2.4	-2.4	-1.4	-1.4	-1.1	-2.7
Pack years of smoking	4.0	5.9	11.1	-2.8	-2.3	-1.2	-1.2	-2.1	-2.7	-2.7	-1.9	-3.3	-2.3	-2.8	-2.4	-3.1	-2.8	-2.6	-1.4	-2.8	-2.0
Ever unenthusiastic/disinterested for a whole week	3.9	4.7	10.1	-2.4	-2.1	-2.6	-1.7	-2.4	-2.9	-1.5	-1.5	-2.2	-1.5	-2.3	-2.7	-3.2	-1.9	-0.8	-1.4	-1.7	-2.9
Headache pain in last month	3.9	6.8	14.1	-2.7	-2.7	-0.3	-0.1	-1.8	-2.4	-2.5	-1.7	-2.9	-3.3	-1.9	-3.2	-2.8	-3.3	-3.8	-3.1	-3.1	-1.9
Back pain experienced in last month	3.9	5.7	11.2	-2.1	-2.0	-1.0	-0.9	-3.2	-2.7	-1.7	-2.7	-2.9	-2.5	-3.0	-3.4	-2.8	-2.5	-2.1	-1.2	-2.1	-2.1
Schizophrenia (2014)	3.8	8.4	14.7	2.5	2.6	0.1	-0.2	3.5	2.6	3.2	3.8	3.2	3.8	2.5	3.5	2.9	3.2	3.1	3.1	3.3	1.7
Pack years adult smoking proportion	3.8	5.8	10.7	-2.6	-2.3	-0.8	-0.8	-2.2	-2.6	-2.7	-1.9	-3.3	-2.4	-2.8	-2.5	-3.0	-2.8	-2.6	-1.6	-2.8	-1.8
Exposure to tobacco smoke outside home	3.7	4.9	11.5	-2.4	-3.4	-0.8	-2.2	-1.8	-2.6	-1.6	-1.8	-2.3	-2.3	-1.7	-2.9	-2.1	-2.7	-2.5	-1.3	-1.5	-2.2
Tinnitus: Yes, now most or all of the time	3.7	4.3	8.9	-2.7	-0.4	-0.1	0.2	-2.4	-1.8	-1.0	-1.9	-2.4	-2.5	-2.6	-1.9	-2.6	-2.2	-2.4	-2.6	-3.0	-0.6
Ovarian Cancer	3.5	4.7	9.9	-2.0	-2.6	0.1	-1.4	-1.7	-2.1	-1.8	-1.4	-2.5	-3.0	-1.1	-2.8	-2.0	-2.7	-3.1	-2.2	-2.4	-1.6
Number of incorrect matches in round	3.4	5.6	16.8	1.1	1.7	-2.4	-0.0	2.2	0.9	2.7	2.0	2.3	3.7	1.7	2.7	0.7	3.3	3.2	4.1	2.5	0.6
Ever depressed for a whole week	3.3	4.1	7.8	-2.3	-2.4	-2.2	-1.6	-2.2	-2.8	-1.1	-1.6	-1.9	-1.6	-1.2	-2.6	-2.6	-2.0	-1.0	-1.6	-1.4	-2.8
Schizophrenia vs Biploar Disorder	3.2	4.3	8.0	2.3	1.8	0.9	0.5	2.4	1.9	2.3	2.8	2.4	2.3	1.4	2.2	2.8	1.8	2.3	1.5	2.5	1.3
Vitamin and mineral supplements	3.2	4.3	8.2	2.9	2.1	2.6	2.1	1.8	2.8	0.5	2.6	2.2	1.2	2.0	1.6	2.7	2.1	1.3	0.9	1.5	2.4
Fed-up feelings	3.2	5.8	9.7	-2.5	-2.1	-0.8	-1.2	-3.1	-2.5	-2.4	-2.5	-2.6	-2.8	-2.3	-2.9	-2.8	-2.6	-2.5	-2.3	-2.6	-1.8
Financial difficulties in last 2 years	3.2	4.4	6.9	-2.5	-2.2	-1.2	-1.5	-2.2	-2.5	-2.1	-2.0	-2.4	-2.4	-0.3	-2.6	-2.6	-2.0	-2.0	-1.6	-2.3	-1.9
Leg fat-free mass (left)	3.1	16.4	35.6	-4.9	-5.0	-5.5	-5.5	-2.2	-5.4	-2.4	-3.7	-4.0	-1.9	-1.7	-3.7	-5.3	-4.0	-2.2	-2.3	-2.6	-6.0
Leg predicted mass (left)	3.1	16.2	35.0	-4.8	-5.0	-5.4	-5.4	-2.2	-5.3	-2.4	-3.6	-4.0	-1.9	-1.7	-3.7	-5.3	-4.0	-2.3	-2.4	-2.6	-5.9
Suffer from ‘nerves’	3.1	4.9	10.4	-2.5	-2.3	-1.1	-1.4	-2.7	-2.5	-2.2	-1.9	-2.5	-2.4	-1.6	-3.2	-2.9	-2.1	-2.0	-1.3	-2.1	-2.1
Impedance of leg (left)	3.0	14.7	26.8	5.1	4.1	3.2	2.9	2.6	4.5	4.2	3.7	4.3	3.5	0.0	3.8	5.2	3.6	3.5	3.5	4.3	4.1
Smoking status: Current	3.0	4.8	10.6	-1.9	-0.5	1.7	1.4	-2.4	-0.9	-2.5	-1.9	-2.5	-3.1	-3.0	-2.0	-1.7	-2.1	-3.2	-2.1	-3.1	0.6
Hypothyroidism (self reported)	2.9	6.7	11.7	-2.5	-3.4	-0.1	-1.2	-2.9	-2.5	-2.8	-2.5	-2.9	-2.9	-2.5	-3.0	-2.3	-3.1	-3.2	-2.4	-2.5	-1.7
Chronotype (morning person)	2.9	6.7	13.0	-3.3	-2.2	-1.4	-0.1	-3.1	-3.1	-1.8	-3.1	-3.2	-2.5	-2.0	-3.1	-3.6	-2.6	-2.7	-1.4	-2.7	-2.1
Frequency of depressed mood in last 2 weeks	2.9	4.1	7.0	-2.2	-2.0	-1.2	-2.0	-2.5	-2.2	-1.8	-2.7	-2.3	-2.0	-1.5	-2.2	-2.4	-2.1	-1.8	-1.5	-2.0	-1.7
Impedance of leg (right)	2.9	13.9	26.4	4.9	4.0	3.2	2.7	2.7	4.4	4.0	3.8	4.1	3.4	0.1	3.6	5.1	3.5	3.5	3.4	4.3	3.9
Current tobacco smoking	2.9	4.8	10.4	-2.1	-1.0	1.3	0.9	-2.5	-1.3	-2.5	-1.9	-2.5	-3.2	-2.6	-2.4	-2.0	-2.1	-3.2	-1.8	-3.0	0.2
Age when periods started (menarche)	2.9	6.9	12.2	-3.3	-2.4	-2.2	-2.7	-3.5	-3.4	-1.6	-2.8	-2.4	-2.0	-2.5	-3.2	-2.9	-2.9	-1.3	-2.1	-1.5	-3.2
Leg fat-free mass (right)	2.9	15.3	31.8	-4.8	-4.7	-5.3	-5.3	-2.2	-5.2	-2.4	-3.7	-3.8	-1.9	-1.6	-3.5	-5.2	-3.8	-2.2	-2.4	-2.6	-5.6
Leg predicted mass (right)	2.9	15.5	31.4	-4.8	-4.7	-5.2	-5.2	-2.3	-5.2	-2.5	-3.7	-3.8	-2.0	-1.6	-3.6	-5.3	-3.8	-2.3	-2.5	-2.7	-5.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.8	4.2	10.3	-2.5	-1.3	-1.5	-1.8	-1.8	-2.2	-1.2	-2.1	-2.6	-1.7	-3.0	-2.2	-3.2	-1.6	-1.8	-0.7	-2.5	-1.6
Knee pain experienced in last month	2.8	4.3	10.6	-2.4	-2.5	-3.2	-2.9	-2.0	-2.9	0.7	-2.0	-1.5	-0.9	-1.0	-2.3	-2.5	-1.6	-0.5	-0.7	-0.6	-3.3
Mother’s age at death	2.8	3.5	5.0	2.2	1.9	1.1	2.1	2.1	2.1	1.4	2.1	1.8	2.0	1.6	2.2	2.1	1.9	1.3	1.5	1.6	1.7
High cholesterol (Self-reported)	2.8	4.9	10.9	-1.9	-2.3	0.6	-0.7	-1.9	-1.7	-2.7	-1.7	-2.2	-2.7	-2.4	-2.4	-1.6	-3.0	-2.9	-3.3	-2.3	-1.4
Medication: Atorvastatin	2.8	3.4	8.5	-1.9	-1.2	0.6	0.1	-1.7	-1.3	-2.9	-1.3	-2.3	-2.2	-1.7	-1.8	-1.5	-2.3	-2.3	-2.4	-2.3	-1.0
BMI	2.7	15.4	32.6	-4.4	-5.7	-3.5	-3.5	-2.4	-5.1	-2.1	-3.2	-4.7	-2.9	-2.4	-4.4	-4.8	-4.5	-4.3	-1.5	-2.9	-5.0
Allergy or Eczema	2.7	7.1	12.2	-3.3	-1.9	-0.7	-2.4	-3.0	-2.9	-1.8	-3.5	-3.3	-3.1	-2.4	-2.9	-3.2	-2.4	-2.7	-1.7	-3.3	-1.6
Hair/balding pattern: Pattern 2	2.7	3.5	6.4	1.6	1.8	-0.1	0.1	1.9	1.7	2.0	2.5	2.4	2.4	2.0	2.1	1.9	2.0	2.1	1.3	2.3	1.0
Medication: Ramipril	2.7	3.5	8.9	1.9	0.4	-0.2	-0.9	2.4	1.3	3.0	2.2	1.9	2.5	0.4	1.8	2.0	1.6	1.6	2.7	2.7	0.5
Lung cancer (father)	2.7	3.2	7.0	-1.8	-2.3	-1.0	-2.6	-2.3	-2.0	-1.9	-2.3	-1.6	-1.7	0.0	-2.4	-1.6	-1.5	-1.0	-0.8	-1.0	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	2.6	3.5	7.7	-1.9	-1.7	-0.8	-1.6	-2.8	-2.0	-1.4	-2.5	-2.0	-1.9	-1.5	-2.1	-2.0	-2.1	-1.8	-1.6	-1.6	-1.5
Ever had prostate specific antigen (PSA) test	2.6	3.0	4.5	2.0	1.9	0.4	1.6	2.0	1.8	1.0	1.9	2.0	1.6	2.1	1.8	1.7	2.1	2.0	1.4	1.7	1.3
Bipolar Disorder or Schizophrenia	2.5	6.2	12.3	2.0	2.2	-0.4	-0.9	2.3	2.0	2.9	2.8	2.7	3.5	1.6	3.0	2.2	3.0	3.0	3.4	2.9	1.5
Systolic Blood Pressure	2.5	12.5	30.8	4.4	1.0	0.7	0.9	3.0	2.9	5.2	3.1	4.5	4.2	2.9	3.8	5.3	2.5	4.0	2.5	5.5	1.3
Hayfever, allergic rhinitis or eczema	2.5	5.3	10.0	-2.7	-1.3	0.0	-1.4	-2.7	-2.1	-1.4	-3.1	-2.7	-3.0	-1.8	-2.3	-2.6	-2.3	-2.8	-2.4	-3.2	-0.8
Weight	2.5	12.0	33.5	-3.9	-4.7	-5.5	-5.2	-1.5	-4.8	-0.8	-2.7	-3.1	-0.8	-1.2	-3.1	-4.4	-3.2	-1.5	-1.0	-1.3	-5.8
Ever highly irritable/argumentative for 2 days	2.5	3.0	6.5	-2.0	-2.5	-1.6	-1.8	-2.4	-2.4	-1.2	-2.0	-1.4	-1.1	-0.8	-2.1	-1.5	-1.9	-1.0	-0.8	-0.5	-2.3
Angina	2.4	3.1	6.9	-2.1	-2.4	-2.5	-2.2	-1.0	-2.5	-0.9	-1.2	-1.5	-1.0	-0.4	-1.7	-2.2	-1.9	-1.1	-1.4	-1.1	-2.6
Neuroticism (2016)	2.3	3.4	9.7	-2.4	-1.6	-1.3	-0.8	-3.1	-2.1	-1.6	-2.4	-1.6	-1.7	-0.1	-2.2	-2.2	-1.9	-1.4	-1.8	-1.4	-1.7
Number of treatments/medications taken	2.3	4.1	13.0	-2.1	-2.8	-2.9	-3.6	-1.0	-2.6	-0.8	-1.0	-1.6	-0.5	-2.0	-1.9	-2.3	-1.9	-0.7	-0.7	-0.5	-3.3
Hip circumference	2.3	10.1	26.1	-3.4	-4.6	-4.2	-4.3	-1.8	-4.5	-1.3	-2.5	-3.0	-1.3	-1.6	-3.3	-3.7	-3.4	-2.0	-1.2	-1.2	-5.1
Pulse wave Arterial Stiffness index	2.3	2.6	5.1	-1.7	-2.2	-1.4	-1.0	-1.7	-2.2	-0.4	-1.8	-1.4	-1.4	-1.5	-2.0	-1.5	-2.1	-1.1	-1.4	-0.7	-2.3
Angina (self-reported)	2.3	3.1	6.2	-1.9	-2.5	-2.0	-2.2	-1.0	-2.4	-1.1	-1.1	-1.6	-1.2	-0.6	-1.8	-2.0	-2.0	-1.4	-1.5	-1.1	-2.5
Risk taking	2.3	3.3	9.6	-2.1	-1.6	-0.3	-1.0	-1.7	-1.8	-1.0	-1.5	-2.2	-2.0	-3.1	-2.1	-2.0	-2.1	-2.2	-1.4	-1.8	-1.0
Noisy workplace	2.2	2.7	5.9	-2.1	-1.6	-1.8	-1.7	-0.2	-2.2	-0.9	-1.0	-2.4	-1.0	-1.0	-1.6	-2.4	-1.6	-1.5	-0.3	-1.7	-2.1
Hypothyroidism/myxoedema (self-reported)	2.2	4.4	7.5	-2.0	-2.5	-0.2	-1.1	-2.4	-1.9	-2.7	-1.8	-2.3	-2.3	-2.0	-2.5	-2.1	-2.3	-2.2	-2.1	-2.2	-1.6
Health satisfaction	2.2	2.8	4.8	-1.8	-1.9	-1.3	-1.2	-1.5	-2.0	-1.8	-1.5	-2.0	-1.5	-0.4	-2.2	-2.1	-1.7	-1.4	-0.9	-1.5	-2.1
Pulse rate, automated reading	2.2	7.1	12.7	-3.3	-2.0	-1.1	-0.6	-3.4	-3.0	-3.6	-2.6	-2.7	-2.9	-1.1	-2.8	-2.9	-3.1	-2.9	-2.9	-2.7	-2.2
Basal metabolic rate	2.2	12.4	30.0	-4.2	-4.3	-5.2	-5.2	-1.5	-4.7	-1.7	-2.8	-3.4	-1.2	-1.8	-3.0	-4.6	-3.4	-1.6	-1.8	-2.0	-5.5
Number of operations (self-reported)	2.2	3.3	8.0	-1.1	-1.8	0.7	-0.2	-0.2	-1.2	-1.4	-1.3	-2.8	-2.6	-2.8	-2.1	-1.5	-2.3	-2.4	-1.3	-2.5	-1.0
Heart disease (siblings)	2.2	2.8	9.1	-1.7	-2.1	-3.0	-1.7	-2.5	-2.2	-0.8	-1.6	-0.8	-0.3	0.2	-1.6	-2.1	-0.8	0.8	-0.8	-0.3	-2.6
Systolic blood pressure, automated reading	2.1	6.0	15.3	3.0	0.1	0.3	0.1	2.4	1.7	3.6	2.2	2.9	2.9	2.8	2.3	3.6	1.8	2.7	2.1	3.9	0.5
Medication: Cholesterol lowering	2.1	3.3	8.1	-1.8	-2.5	-1.5	-2.9	-1.1	-2.2	-1.1	-1.3	-1.9	-1.1	-2.0	-1.8	-1.9	-1.9	-1.3	-1.1	-1.2	-2.4
Arm fat mass (right)	2.1	8.5	23.9	-3.2	-4.2	-4.6	-4.1	-1.6	-4.1	-0.6	-2.5	-2.5	-0.6	-0.6	-2.7	-3.5	-2.6	-1.4	-0.3	-0.7	-4.9
Breastfed as a baby	2.1	2.5	6.6	2.3	1.2	1.5	0.6	1.8	1.9	0.5	1.5	1.5	1.0	2.6	2.0	2.1	1.6	0.9	0.7	0.8	1.9
Chest pain or discomfort	2.1	3.1	5.0	-1.8	-1.7	-1.1	-2.1	-1.4	-2.0	-0.4	-2.2	-2.2	-1.9	-2.0	-2.1	-2.0	-1.8	-1.7	-0.4	-1.6	-1.6
Whole body fat-free mass	2.1	12.0	27.1	-4.2	-3.9	-5.0	-5.0	-1.5	-4.5	-1.9	-2.8	-3.4	-1.3	-1.9	-2.9	-4.7	-3.4	-1.6	-2.1	-2.3	-5.2
Whole body water mass	2.1	11.8	27.8	-4.2	-3.9	-5.1	-5.1	-1.5	-4.5	-1.8	-2.8	-3.3	-1.2	-1.8	-2.9	-4.6	-3.3	-1.5	-2.1	-2.1	-5.3
Commuting to job workplace: Public transport	2.1	2.5	5.8	-2.0	-2.4	-1.1	-1.6	-2.1	-1.7	-1.0	-2.1	-0.9	-1.5	0.3	-2.1	-1.4	-1.5	-0.8	-1.7	-0.6	-1.9
Mouth/teeth dental problems: Dentures	2.0	3.4	8.1	-2.1	-2.4	-0.4	-0.8	-2.1	-2.1	-2.4	-1.7	-1.9	-2.1	-0.4	-2.8	-1.6	-2.1	-1.9	-1.1	-1.2	-1.9
Gout (self-reported)	2.0	2.8	5.8	2.0	1.7	0.9	0.8	2.1	2.1	1.8	2.0	1.5	1.7	0.2	2.4	1.5	1.7	1.1	1.7	1.0	2.1
Reason for reducing amount of alcohol drunk: Health precaution	2.0	2.3	5.2	1.9	1.0	1.0	1.4	1.9	1.6	1.7	1.7	1.9	1.2	1.1	1.5	2.3	1.2	1.0	0.9	1.8	1.1
Handedness (chirality/laterality): Left-handed	2.0	2.5	4.6	1.4	2.1	-0.2	1.6	1.9	1.4	1.5	1.5	1.6	1.9	1.6	1.8	1.0	2.0	1.6	1.6	1.3	1.0
Guilty feelings	2.0	3.0	5.7	-1.4	-2.3	-0.6	-0.8	-1.8	-1.9	-1.8	-2.3	-1.8	-2.2	0.5	-2.4	-1.5	-2.0	-2.0	-1.2	-1.3	-1.6
Medication: Co-codamol	1.9	2.2	4.2	-1.6	-2.1	-1.2	-1.2	-0.5	-1.8	-0.8	-1.5	-1.8	-1.3	-0.5	-1.8	-1.6	-1.9	-1.6	-0.7	-1.0	-2.1
Loud music exposure frequency	1.9	2.1	4.5	-1.9	-1.5	-0.9	-0.3	-1.0	-1.6	-0.7	-1.4	-1.9	-1.5	-0.7	-1.4	-2.1	-1.6	-1.9	-1.2	-1.9	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	1.9	2.5	6.7	-2.2	-0.9	-2.3	-0.8	-1.7	-2.0	-0.7	-2.3	-1.7	-0.6	-2.0	-0.8	-2.6	-1.2	-0.9	-0.1	-1.4	-1.2
Medication: Ibuprofen	1.9	2.2	4.5	-1.8	-1.0	-1.4	-2.0	-1.7	-1.8	-2.1	-1.2	-1.6	-0.9	-0.5	-1.8	-2.1	-1.1	-1.0	-0.4	-1.2	-1.7
Medication: Allopurinol	1.9	2.6	4.6	2.1	1.1	0.6	0.1	2.1	1.9	1.7	1.9	1.6	1.7	0.9	1.9	1.8	1.7	1.5	1.8	1.5	1.5
Whole body fat mass	1.9	7.9	24.4	-3.0	-4.0	-4.9	-4.4	-1.4	-4.0	0.1	-2.2	-2.1	-0.0	-0.9	-2.3	-3.3	-2.3	-0.9	0.2	-0.2	-4.8
Arm fat mass (left)	1.9	7.7	21.3	-3.1	-3.9	-4.5	-3.9	-1.6	-3.9	-0.5	-2.4	-2.3	-0.5	-0.5	-2.5	-3.4	-2.4	-1.2	-0.4	-0.7	-4.6
Fractured/broken bones in last 5 years	1.9	2.4	6.1	-1.4	-2.1	-0.0	-1.7	-1.4	-1.6	-1.2	-1.5	-1.7	-2.2	-0.4	-2.5	-1.3	-1.6	-1.7	-0.9	-1.3	-1.3
Birth weight of first child	1.8	3.3	11.5	-2.6	-1.0	-3.1	-1.1	-1.0	-2.2	-1.1	-2.5	-2.0	-0.6	0.1	-1.6	-3.4	-0.4	-0.2	0.2	-1.9	-2.3
Pulse wave peak to peak time	1.8	2.1	3.7	1.5	1.9	0.9	0.7	1.6	1.9	0.5	1.7	1.3	1.5	1.4	1.9	1.2	1.9	1.2	1.4	0.7	1.8
Overall health rating	1.8	3.9	8.8	-2.2	-3.0	-1.9	-2.3	-1.6	-2.6	-1.2	-1.1	-1.8	-1.5	-1.3	-2.8	-2.2	-2.1	-1.7	-0.7	-0.8	-2.7
Medication for cholesterol	1.8	2.7	7.7	0.9	2.8	-0.1	-0.0	1.6	1.7	0.7	0.9	1.2	1.8	1.9	2.2	0.6	2.7	2.3	1.9	0.4	1.6
Fasting Glucose	1.7	2.0	4.6	-0.4	-0.5	0.8	-0.7	-0.3	-0.9	-1.8	-0.6	-1.8	-1.8	-2.1	-1.5	-1.0	-2.2	-2.1	-2.1	-1.7	-0.8
Body mass index (BMI)	1.7	7.3	15.8	-3.1	-3.8	-3.2	-3.1	-1.7	-3.7	-1.3	-2.2	-2.9	-1.5	-0.7	-2.9	-3.5	-2.7	-2.3	-0.8	-1.6	-4.0
Medication for pain relief, constipation, heartburn	1.7	3.0	6.3	2.3	1.3	1.5	2.2	1.4	1.9	1.9	0.9	2.0	1.3	1.9	1.9	2.5	1.5	1.3	0.7	1.8	1.7
Leg fat mass (right)	1.7	6.6	19.6	-2.5	-3.8	-4.1	-3.9	-1.2	-3.6	-0.1	-1.8	-2.2	-0.3	-1.2	-2.4	-2.9	-2.3	-1.1	0.2	-0.3	-4.4
Leg fat mass (left)	1.7	6.5	18.7	-2.5	-3.7	-4.0	-3.9	-1.3	-3.6	-0.1	-1.9	-2.2	-0.3	-1.3	-2.4	-3.0	-2.3	-1.2	0.2	-0.4	-4.3
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	4.2	-1.9	-2.0	-2.0	-2.0	-1.2	-1.9	-0.9	-0.8	-1.4	-0.6	-0.6	-1.2	-1.9	-1.2	-0.8	-0.4	-1.0	-1.9
Medication: Levothyroxine sodium	1.6	2.7	5.2	-1.5	-1.5	0.4	0.1	-1.4	-1.1	-2.1	-1.2	-1.9	-2.2	-1.3	-1.9	-1.6	-1.8	-2.3	-2.1	-2.3	-0.7
Trunk fat mass	1.6	7.1	25.4	-2.5	-3.8	-5.0	-4.4	-1.1	-3.7	0.6	-2.0	-1.6	0.4	-0.6	-1.9	-2.8	-2.0	-0.4	0.4	0.4	-4.8
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	5.9	-1.8	-0.5	-1.3	-1.5	-1.2	-1.5	-2.3	-1.1	-1.8	-1.0	-0.6	-1.6	-2.4	-0.7	-1.0	-0.2	-1.7	-1.2
Medication: Amlodipine	1.6	2.2	4.4	2.1	1.7	0.6	-0.2	0.8	1.5	0.7	1.5	1.6	1.8	1.2	1.9	1.6	1.9	1.7	1.7	1.5	1.4
Medication: Blood pressure	1.6	2.9	6.5	2.2	0.0	-1.1	-0.7	2.0	0.9	2.0	1.6	1.5	2.4	1.1	1.9	1.4	1.7	2.3	2.5	2.2	-0.1
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	3.8	2.0	1.3	1.1	1.1	1.3	1.8	0.3	0.9	1.7	1.1	0.4	1.3	1.9	1.8	1.4	1.6	1.5	1.4
Mouth/teeth dental problems: Mouth ulcers	1.6	2.6	4.2	-1.5	-2.0	-1.3	-1.7	-1.5	-2.0	-0.8	-1.7	-1.3	-1.5	-1.2	-1.9	-1.5	-2.1	-1.2	-1.9	-1.0	-2.0
Impedance of whole body	1.6	8.1	16.3	3.8	2.6	1.7	1.6	1.5	3.0	3.4	2.1	3.6	2.8	0.9	2.8	4.0	2.8	3.1	2.8	3.8	2.6
Heel bone mineral density (BMD) T-score, automated (left)	1.5	3.4	9.6	2.8	0.9	1.5	0.6	1.5	1.9	1.7	2.2	2.4	1.9	-0.2	1.9	3.1	1.2	1.7	0.9	2.7	1.3
Waist circumference	1.5	5.4	14.1	-2.7	-3.1	-3.7	-3.0	-1.1	-3.4	-0.6	-1.8	-2.3	-0.6	-0.6	-2.1	-3.2	-2.0	-1.4	-0.2	-1.1	-3.8
Trunk fat-free mass	1.5	8.5	21.0	-3.5	-3.1	-4.6	-4.5	-0.8	-3.8	-1.4	-1.9	-2.8	-0.8	-1.7	-2.2	-4.1	-2.7	-1.1	-1.7	-1.9	-4.6
Arm fat-free mass (left)	1.5	7.6	19.4	-3.1	-3.2	-4.2	-4.4	-0.9	-3.6	-0.9	-1.9	-2.7	-0.7	-1.9	-2.2	-3.6	-2.7	-1.1	-1.3	-1.5	-4.4
Cholesterol lowering medication	1.5	2.3	6.1	-1.0	-2.1	0.5	0.4	-1.1	-1.2	-1.5	-0.7	-1.2	-2.1	-0.9	-2.0	-0.6	-2.3	-2.1	-2.5	-1.0	-1.2
Supplements: Zinc	1.4	1.6	6.1	-0.3	-1.4	-1.9	-2.5	-0.2	-1.2	2.0	-1.0	0.0	0.5	-1.4	-0.4	0.1	-0.9	0.9	0.2	1.2	-2.0
Taking other prescription medications	1.4	2.1	9.5	-1.4	-2.1	-2.1	-3.1	-0.8	-1.9	-1.1	-0.9	-1.2	-0.0	-0.6	-1.2	-1.5	-1.2	-0.3	-0.0	-0.2	-2.3
Qualifications: CSEs or equivalent	1.4	1.9	5.4	-2.0	-1.0	-1.3	-1.4	-1.4	-1.7	-0.8	-1.2	-1.7	-0.8	0.1	-2.0	-2.3	-0.6	-1.0	0.1	-1.3	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.1	7.1	2.5	1.1	0.6	0.9	1.1	1.6	2.0	1.8	2.5	2.1	-0.2	2.0	2.6	1.4	2.0	1.2	2.7	1.1
Arm fat percentage (right)	1.4	5.7	16.2	-2.6	-3.7	-3.8	-3.0	-1.7	-3.5	-0.6	-2.2	-1.8	-0.5	0.4	-2.3	-2.8	-2.0	-1.2	-0.1	-0.3	-4.0
Hair/balding pattern: Pattern 3	1.4	2.0	5.6	-2.3	-1.2	-1.8	0.6	-1.4	-1.9	-0.4	-2.4	-1.5	-1.0	0.3	-1.1	-2.2	-0.8	-1.0	-0.4	-1.4	-1.3
Number of live births	1.4	2.0	4.5	-1.1	-2.0	-0.1	0.0	-0.8	-1.5	-1.0	-0.7	-1.5	-1.6	-1.2	-1.5	-1.2	-2.1	-2.1	-2.0	-1.4	-1.3
Trunk predicted mass	1.4	8.0	20.6	-3.4	-3.0	-4.5	-4.5	-0.8	-3.7	-1.3	-1.9	-2.6	-0.6	-1.6	-2.1	-3.9	-2.6	-0.9	-1.6	-1.7	-4.5
Tense / ‘highly strung’	1.4	2.3	7.3	-1.1	-0.5	0.7	-0.6	-1.9	-0.9	-1.3	-1.7	-1.6	-2.2	-2.7	-1.7	-1.4	-1.5	-1.8	-1.3	-1.8	-0.0
Arm fat-free mass (right)	1.4	7.0	19.5	-3.0	-2.9	-4.1	-4.4	-1.0	-3.4	-1.0	-1.9	-2.5	-0.6	-2.0	-2.0	-3.6	-2.4	-0.9	-1.3	-1.5	-4.1
Arm predicted mass (right)	1.4	7.1	18.2	-3.0	-3.0	-4.0	-4.3	-0.8	-3.4	-1.1	-2.0	-2.6	-0.8	-2.1	-2.0	-3.6	-2.6	-1.1	-1.3	-1.6	-4.0
Number of full sisters	1.4	1.7	4.2	-0.6	-1.3	1.7	1.2	-1.0	-0.3	-1.8	-1.1	-1.7	-2.0	-0.2	-1.3	-0.7	-1.0	-2.0	-0.8	-1.9	0.5
Commuting to job workplace: Walk	1.4	1.6	2.8	-1.6	-1.1	-1.0	-1.6	-0.6	-1.5	-1.0	-1.1	-1.5	-0.9	-0.2	-1.3	-1.6	-1.4	-1.1	-1.1	-1.2	-1.7
Arm predicted mass (left)	1.4	7.3	19.1	-3.0	-3.2	-4.2	-4.3	-0.8	-3.6	-0.8	-1.7	-2.6	-0.6	-1.9	-2.2	-3.6	-2.6	-1.1	-1.2	-1.4	-4.4
Mean Putamen Volume	1.3	1.5	5.2	0.7	1.1	-0.9	-0.5	1.5	0.6	1.2	1.2	0.9	1.9	1.4	1.0	0.5	1.5	1.6	2.3	1.4	-0.1
Exposure to tobacco smoke at home	1.3	1.5	3.5	-1.6	-0.8	0.2	0.2	-1.3	-1.1	-1.1	-1.1	-1.5	-1.6	-0.7	-1.2	-1.3	-1.4	-1.9	-1.1	-1.6	-0.4
Blood clot in the leg (DVT)	1.3	1.7	4.5	-2.0	-1.8	-1.0	-2.1	-1.0	-1.4	-1.3	-1.4	-1.4	-0.8	-0.1	-1.4	-1.4	-1.1	-0.8	-0.1	-0.7	-1.5
Emphysema/chronic bronchitis	1.3	1.5	4.4	-1.3	-0.9	-0.7	-1.2	-1.5	-1.4	-0.0	-1.3	-1.3	-0.9	-2.1	-1.0	-1.4	-1.5	-1.1	-1.1	-1.1	-1.0
Arm fat percentage (left)	1.3	5.1	14.3	-2.5	-3.4	-3.8	-2.9	-1.6	-3.3	-0.4	-2.1	-1.6	-0.3	0.3	-2.0	-2.6	-1.8	-1.0	0.0	-0.2	-3.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.6	5.2	-1.6	-1.4	-2.3	-0.2	-0.7	-1.7	0.3	-1.1	-1.0	-0.4	-0.1	-1.0	-1.8	-1.4	-0.4	-1.1	-0.7	-2.1
Medication: Aspirin	1.3	1.6	3.8	-1.4	-1.7	-1.7	-1.9	-0.2	-1.5	-0.5	-0.5	-1.2	-0.5	-1.7	-0.9	-1.5	-1.4	-0.8	-0.8	-0.8	-1.8
Unable to work because of sickness or disability	1.3	1.7	3.7	-1.0	-1.8	-0.4	-1.9	-0.1	-1.5	0.1	-0.9	-1.6	-1.5	-1.4	-1.6	-0.9	-1.9	-1.6	-0.7	-0.9	-1.5
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	3.5	-1.8	-1.8	-0.6	-1.9	-0.9	-1.3	-1.3	-1.2	-1.5	-1.1	-0.5	-1.6	-1.3	-1.2	-1.1	-0.2	-0.9	-1.3
Stomach or abdominal pain in last month	1.2	1.4	4.1	-0.9	-0.6	0.7	0.5	-1.4	-0.8	-1.9	-0.6	-1.3	-1.8	-1.0	-1.4	-0.9	-1.3	-2.0	-0.9	-1.5	0.0
Supplements: Glucosamine	1.2	1.5	4.5	1.7	1.5	0.2	0.6	-0.4	1.1	1.0	0.2	2.1	1.0	0.6	0.7	1.5	1.6	2.1	0.6	1.8	0.9
Medication: Simvastatin	1.2	1.8	6.0	-1.2	-2.5	-1.1	-1.8	-0.7	-1.5	-0.8	-0.7	-1.1	-1.0	-0.9	-1.6	-1.1	-1.8	-1.0	-1.3	-0.6	-2.0
Pulse rate	1.2	2.1	3.8	-1.7	-1.0	0.0	-0.6	-2.0	-1.4	-1.8	-1.3	-1.6	-1.9	-0.3	-1.8	-1.3	-1.6	-1.9	-1.4	-1.6	-0.9
Heart disease (mother)	1.2	1.4	8.1	-1.3	-1.7	-1.7	-2.8	-0.6	-1.2	0.6	-1.0	-0.5	0.3	0.8	-0.8	-0.6	-0.3	0.1	1.2	0.7	-1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	4.0	0.6	0.4	-0.5	-1.4	0.4	0.7	1.7	0.9	1.3	1.7	0.8	1.0	1.2	1.3	2.0	1.3	1.7	0.1
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	4.7	-0.4	-0.3	-2.1	-2.1	0.6	-0.7	1.4	0.6	0.4	1.5	0.7	-0.0	-0.5	1.0	1.0	2.2	1.2	-1.3
Supplements: Vitamin C	1.2	1.4	3.2	-1.4	-0.9	-1.7	-1.2	-1.1	-1.6	-0.6	-1.2	-0.8	-0.2	-1.4	-0.9	-1.4	-1.4	-0.5	-1.2	-0.5	-1.8
Vascular/heart problems diagnosed by doctor	1.2	3.2	9.7	-2.6	0.2	0.5	0.8	-2.3	-1.1	-3.1	-1.8	-1.9	-1.9	-0.9	-1.9	-2.1	-1.2	-1.7	-1.9	-2.5	-0.3
Alzheimer’s Disease (in mother)	1.1	1.3	3.7	-1.9	-0.7	-0.7	1.4	-1.4	-1.1	-0.3	-0.6	-1.0	-0.8	1.0	-0.9	-1.9	-0.3	-1.1	-1.0	-1.6	-0.6
Verbal and Numeric Reasoning (VNR)	1.1	2.7	7.3	-1.2	-2.1	-0.3	-1.8	-1.4	-1.7	-0.0	-1.3	-1.4	-1.6	-2.7	-1.5	-1.1	-2.4	-1.9	-1.9	-1.1	-1.3
HbA1C	1.1	1.2	4.1	-0.9	-0.6	1.2	-0.0	-1.6	-0.7	-2.0	-0.8	-0.9	-1.6	-0.2	-1.4	-0.6	-0.8	-1.0	-1.6	-1.3	0.0
Blood Eosinophil Count	1.1	8.5	24.4	-1.6	-4.9	-0.3	-0.0	-3.3	-3.1	-2.5	-2.6	-2.7	-3.6	-0.4	-4.1	-1.9	-3.9	-2.8	-3.7	-1.9	-3.2
Smoking Status	1.1	2.7	4.7	-2.0	-2.0	-0.1	-0.8	-2.1	-1.6	-1.3	-2.0	-2.1	-2.1	-1.0	-2.2	-1.6	-1.7	-2.0	-0.5	-1.6	-1.0
Average weekly spirits intake	1.1	1.3	2.3	-1.2	-1.3	-0.5	-0.9	-1.3	-1.3	-1.3	-1.3	-1.5	-1.3	-0.2	-1.5	-1.4	-1.0	-1.2	-0.3	-1.2	-0.9
Trunk fat percentage	1.1	4.2	16.5	-1.6	-3.1	-4.1	-3.4	-0.9	-2.8	1.1	-1.5	-0.8	0.8	-0.1	-1.3	-1.7	-1.3	0.0	1.1	1.1	-3.7
Average weekly fortified wine intake	1.1	1.2	4.0	1.1	1.2	1.2	1.2	0.7	1.3	0.6	0.8	0.6	0.5	0.5	1.3	1.1	1.5	0.4	1.9	0.4	2.0
High blood pressure	1.1	3.0	10.6	2.5	0.2	-0.3	-0.5	2.1	1.2	3.2	1.4	1.9	1.7	0.6	2.0	2.1	1.3	1.7	1.9	2.3	0.7
Number of full brothers	1.1	1.4	3.6	-0.7	-1.2	0.3	-0.6	-0.9	-1.2	-1.4	-0.6	-1.4	-1.7	-1.0	-1.6	-1.1	-1.6	-1.9	-1.1	-1.3	-0.7
Shortness of breath walking on level ground	1.1	1.3	3.0	-1.1	-1.4	-1.2	-0.3	-1.1	-1.5	-0.5	-1.7	-0.9	-0.9	-0.4	-1.2	-1.1	-1.5	-0.8	-1.3	-0.5	-1.6
Qualifications: College or University degree	1.1	3.5	8.6	-1.9	-0.5	0.4	1.0	-1.2	-1.1	-1.8	-2.5	-2.0	-2.7	-1.7	-1.2	-1.8	-2.1	-2.5	-2.9	-2.9	-0.1
Medication: Aspirin	1.1	1.4	4.0	-1.4	-1.6	-1.8	-2.0	-0.1	-1.4	-0.4	-0.4	-1.0	-0.2	-1.0	-0.7	-1.4	-1.2	-0.7	-0.7	-0.6	-1.8
Illnesses of father: Heart disease	1.1	1.5	4.8	-2.2	-1.7	-1.4	-0.9	-1.4	-1.7	-0.3	-1.8	-0.8	-0.8	-1.0	-1.2	-1.4	-0.9	-0.7	-0.2	-0.4	-1.2
Alzheimer’s Disease (including proxy)	1.0	1.4	4.1	-1.8	-1.2	-1.0	1.5	-0.6	-1.3	-0.7	-0.7	-1.5	-0.8	-0.7	-0.9	-2.0	-0.8	-1.4	-0.3	-1.6	-0.8
Multivitamins +/- minerals	1.0	1.2	4.3	-1.4	-0.8	-1.9	-2.1	-0.4	-1.4	1.5	-1.3	-0.5	-0.2	-1.1	-0.5	-1.2	-0.7	-0.2	-0.1	-0.2	-1.3
Had menopause	1.0	1.2	3.3	1.8	0.6	1.1	1.4	1.0	1.4	1.1	1.2	1.1	0.6	0.3	0.8	1.4	1.1	0.7	1.1	1.0	1.2
Body fat percentage	1.0	3.8	13.3	-1.6	-3.1	-3.6	-3.1	-0.9	-2.7	0.8	-1.4	-1.0	0.5	-0.3	-1.4	-1.8	-1.4	-0.3	1.0	0.8	-3.5
Wheeze or whistling in the chest in last year	1.0	1.8	4.0	-1.3	-0.7	-0.6	-1.9	-1.9	-1.5	-0.3	-2.0	-1.4	-1.3	-0.5	-1.4	-1.4	-1.6	-1.4	-1.3	-1.2	-1.1
Age at first live birth	1.0	1.7	4.6	1.9	1.6	2.1	0.8	0.8	2.0	0.6	0.7	1.3	0.3	0.9	1.4	1.9	1.2	0.6	0.0	0.5	2.1
Comparative height size at age 10	1.0	5.4	14.0	2.3	1.5	-1.8	-1.7	3.4	1.6	1.9	2.5	2.1	3.7	0.6	2.7	1.4	2.4	3.4	2.9	2.7	0.1
Hypertension (Self-reported)	1.0	2.7	9.8	2.7	0.0	0.1	-0.5	2.1	1.2	3.1	1.3	1.7	1.6	0.2	2.0	2.2	0.9	1.3	1.6	2.2	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	4.1	0.7	1.4	-0.1	1.0	0.4	0.9	-0.2	0.8	1.1	1.5	2.0	1.1	0.5	1.6	1.5	1.0	0.8	0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.1	7.0	-1.5	-1.5	-0.7	-2.6	-0.9	-1.3	-0.7	-1.3	-1.8	-1.0	-2.3	-1.4	-1.5	-1.6	-1.0	-0.7	-1.2	-1.4
Wears glasses or contact lenses	1.0	1.1	5.1	-1.4	-0.6	-2.2	-1.0	-1.0	-1.4	-0.9	-0.9	-0.6	0.1	0.3	-0.8	-2.0	0.3	0.4	0.5	-0.6	-1.3
Ulcerative Colitis (UC)	0.9	1.6	4.2	1.3	0.3	0.2	-0.1	0.5	0.9	0.7	1.6	2.1	1.3	2.0	0.8	1.7	1.4	1.8	0.6	1.9	0.4
Respiratory disease	0.9	2.0	4.6	-1.6	-1.4	-1.8	-2.2	-1.5	-1.8	0.9	-1.9	-0.8	-0.8	-0.8	-1.2	-1.5	-1.3	-0.3	-1.4	-0.6	-1.8
High blood pressure (mother)	0.9	1.3	4.2	1.9	-0.0	0.7	-0.3	2.1	0.9	1.2	1.5	0.9	0.7	1.2	0.3	1.8	0.5	0.6	1.2	1.6	-0.1
Depression (self-reported)	0.9	1.1	3.0	-1.2	-0.1	-0.7	-0.1	-1.6	-1.1	-1.5	-0.6	-1.1	-0.7	-1.7	-1.1	-1.6	-0.7	-0.8	-0.7	-1.2	-0.6
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.0	-0.7	-1.0	0.1	0.2	-1.1	-1.0	-0.9	-1.0	-1.3	-1.4	-0.5	-1.4	-0.8	-1.4	-1.2	-1.0	-1.0	-0.9
Number of children fathered	0.9	1.0	3.5	0.2	0.4	1.9	1.6	-0.6	0.5	-1.6	0.4	-0.7	-1.0	-1.5	-0.6	-0.1	-0.5	-0.9	-1.3	-1.2	0.8
Medication: Seretide 50 evohaler	0.9	1.1	4.2	-0.7	-0.5	-2.0	-1.7	0.8	-0.9	2.1	0.1	0.1	0.9	-0.1	0.2	-0.5	0.1	0.5	1.4	0.8	-1.1
Ever taken oral contraceptive pill	0.9	0.9	2.3	-1.3	-0.6	-0.6	0.5	-0.6	-0.9	-1.5	-0.4	-1.1	-0.7	0.6	-0.9	-1.3	-0.9	-0.9	-1.3	-1.3	-0.9
Hearing aid user	0.9	1.0	5.2	0.1	0.3	2.0	0.6	-0.6	0.2	-2.3	0.5	-1.0	-1.2	-0.2	-0.9	-0.1	-0.5	-1.6	-0.5	-1.3	0.8
Reaction Time	0.8	1.5	3.9	0.8	0.5	-0.9	-0.4	1.3	0.6	1.6	0.9	1.2	1.8	1.2	1.2	0.8	1.5	1.6	2.0	1.5	0.1
Eye problems/disorders: Diabetes related eye disease	0.8	0.8	2.9	-0.8	-0.7	0.2	-0.9	-0.5	-0.8	-0.6	-0.0	-0.8	-1.2	-1.7	-1.1	-0.4	-1.4	-1.1	-1.3	-0.6	-0.6
Had other major operations	0.8	0.9	3.5	-0.0	-0.3	0.9	0.6	0.3	-0.1	-0.7	0.0	-1.4	-1.5	-1.9	-1.0	-0.8	-0.7	-1.5	-0.3	-1.6	0.2
Happiness	0.8	0.9	3.0	-1.1	-0.7	-1.6	-0.9	-1.1	-1.3	-0.1	-1.1	-0.8	-0.7	-0.0	-1.1	-1.7	-0.2	-0.2	0.1	-0.9	-1.0
High blood pressure (siblings)	0.8	1.2	3.0	1.1	0.9	0.3	0.5	1.1	1.1	1.7	1.6	1.2	1.4	0.6	1.0	1.1	0.9	1.0	0.7	1.4	0.4
Illnesses of siblings: Diabetes	0.8	0.9	2.8	1.0	0.9	1.7	1.5	-0.0	1.2	-0.6	1.0	0.8	-0.1	1.6	0.2	1.0	0.9	-0.1	0.3	0.2	1.4
Smoking status: Previous	0.8	1.1	5.7	-0.4	-1.6	-1.9	-2.4	-0.4	-1.0	0.6	-0.7	-0.1	0.5	0.9	-0.4	-0.4	0.0	0.9	1.3	0.8	-1.5
Medication: Gliclazide	0.8	0.9	3.6	-0.9	-1.5	-1.3	-1.8	-0.5	-1.1	-0.3	0.0	-0.5	0.1	1.9	-0.7	-0.8	0.1	0.1	0.8	0.0	-1.3
Number of self-reported non-cancer illnesses	0.8	1.4	2.4	-1.1	-1.5	-1.1	-1.6	-0.6	-1.5	-0.3	-1.0	-1.4	-1.0	-1.2	-1.3	-1.6	-1.1	-1.2	-0.4	-1.1	-1.3
Alcohol drinker status: Never	0.8	1.0	4.8	0.7	0.6	1.4	2.2	1.5	0.7	-0.5	1.7	-0.0	-0.8	0.3	0.0	0.3	0.1	-1.0	-0.5	-0.7	1.0
Myopia	0.8	1.1	3.7	-1.3	-0.4	-1.0	-1.1	-0.2	-1.0	-1.4	-0.7	-1.2	-0.9	0.4	-0.8	-1.9	-0.6	-1.1	-0.9	-1.7	-0.8
Basal cell carcinoma (self-reported)	0.8	1.0	2.9	0.2	0.8	-0.6	-1.0	1.1	0.5	0.7	1.1	1.0	1.2	1.7	0.8	0.4	1.5	1.2	1.4	0.8	0.2
Crohns Disease (2017)	0.7	1.6	4.1	-0.9	-1.4	-0.3	-1.2	-1.5	-1.3	-2.0	-0.6	-1.4	-1.3	-1.0	-1.8	-1.3	-1.2	-1.2	-0.8	-1.1	-1.1
Body Mass Index (BMI) (2010)	0.7	1.0	3.1	0.2	-1.2	0.3	-1.8	0.8	-0.4	-0.8	1.1	-1.0	-0.7	-1.7	-1.1	-0.3	-0.7	-1.4	1.3	-0.2	-0.4
Blood Platelet Count	0.7	8.0	43.3	3.5	1.2	6.6	5.3	-1.2	3.1	-0.3	1.7	1.7	-1.5	1.3	0.2	3.8	0.7	-1.1	-1.7	0.5	4.2
Blood White Count	0.7	5.2	17.6	-1.5	-4.2	0.1	-0.9	-1.5	-2.4	-2.8	-0.9	-2.4	-2.7	0.5	-3.2	-1.0	-3.2	-3.1	-1.9	-1.2	-2.5
Hand grip strength (left)	0.7	1.9	4.4	1.4	1.6	-0.4	-0.4	2.0	1.3	1.6	1.6	1.6	1.9	0.1	1.8	1.3	1.2	2.1	0.5	1.5	0.4
Diabetes (father)	0.7	0.9	3.1	-0.5	-1.5	-0.8	-1.8	-1.5	-1.2	0.2	-1.0	-0.2	-0.6	-0.1	-1.5	-0.3	-0.5	0.1	0.4	0.5	-1.3
Diabetes (mother)	0.7	0.9	3.3	0.1	0.9	1.8	1.1	0.5	0.8	-1.1	0.2	-0.1	-0.7	1.5	0.2	0.3	0.8	-1.0	0.7	-0.8	1.8
Relative age voice broke	0.7	1.1	3.5	-1.6	-0.8	-1.9	-0.1	-1.3	-1.3	-0.4	-1.5	-0.4	-0.5	1.1	-0.8	-1.8	-0.0	-0.0	-0.6	-0.8	-1.0
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.0	0.6	0.5	-0.8	-0.1	1.0	0.3	1.3	-0.2	0.6	0.9	1.0	0.5	0.3	1.2	1.3	1.7	0.8	-0.1
Past tobacco smoking	0.7	1.4	3.9	1.1	1.8	1.0	2.0	1.5	1.4	0.7	1.5	1.2	0.9	0.0	1.2	1.1	1.0	0.5	-0.1	0.5	1.3
Alcohol usually taken with meals	0.7	1.2	3.1	1.0	1.1	-0.2	0.8	1.8	1.1	0.5	1.6	1.1	1.1	1.1	1.1	0.7	1.5	1.3	1.0	0.7	0.6
Alcohol intake versus 10 years previously	0.7	1.1	5.0	-0.6	-1.3	-1.8	-2.2	0.3	-1.1	0.8	-0.1	-0.9	0.3	-0.6	-0.5	-1.4	-0.2	0.2	1.0	-0.4	-1.4
Asthma	0.7	1.4	3.2	-1.1	-0.5	0.3	-1.4	-1.6	-1.0	0.4	-1.5	-0.8	-1.7	-1.4	-1.2	-0.8	-1.4	-1.3	-1.8	-1.1	-0.3
Medication: Lansoprazole	0.7	0.8	2.4	-0.1	-1.0	-1.4	-1.3	-0.6	-0.8	-0.2	-0.3	0.2	0.7	1.5	-0.4	-0.0	0.1	1.0	1.0	1.2	-1.2
Glaucoma (self-reported)	0.7	0.8	4.2	0.5	-0.8	-1.0	-1.2	1.2	0.1	1.2	0.8	0.4	0.9	2.0	0.5	-0.0	0.6	0.3	0.9	0.5	-0.6
Migraine (self-reported)	0.7	0.9	5.2	0.2	0.3	1.4	0.9	0.4	0.5	-2.3	0.9	-0.7	-1.0	1.3	-0.5	-0.1	0.2	-1.3	0.3	-1.1	0.8
Had major operations	0.7	0.9	3.3	-1.0	-1.8	-1.0	-1.7	-0.2	-1.1	-0.0	-0.9	-0.8	-0.3	-0.4	-0.7	-0.5	-1.1	-0.4	-0.4	-0.1	-1.5
Asthma (self-reported)	0.7	1.4	3.2	-1.1	-0.5	0.1	-1.5	-1.5	-1.1	0.6	-1.5	-0.8	-1.6	-1.3	-1.2	-0.9	-1.3	-1.3	-1.8	-1.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	4.3	1.0	1.3	0.4	0.9	0.8	1.4	1.0	1.1	1.2	1.5	0.4	1.2	1.4	1.4	2.1	1.3	1.5	0.5
Supplements: Fish oil (including cod liver oil)	0.7	1.0	3.7	-0.6	0.5	-1.9	-0.9	-1.1	-0.6	1.7	-1.2	0.9	1.1	0.0	0.7	-0.2	0.4	1.3	0.5	1.1	-0.6
Diastolic blood pressure, automated reading	0.7	2.1	5.3	2.1	-0.5	0.8	1.4	2.2	0.8	1.8	2.0	1.3	1.0	1.6	1.2	2.3	0.5	0.2	1.1	1.9	0.4
Commuting to job workplace: Cycle	0.7	0.9	3.7	1.2	0.4	1.9	0.5	-0.2	1.1	-0.5	0.4	0.9	-0.1	1.2	0.6	1.7	0.1	0.0	-1.0	0.5	1.1
Alcohol drinker status: Previous	0.7	0.8	1.7	-1.3	-0.9	-0.8	-1.2	0.3	-1.2	-0.2	-0.0	-1.1	-0.6	-0.7	-1.0	-1.0	-1.0	-1.2	0.5	-0.4	-1.0
Alzheimer’s Disease (in father)	0.6	0.6	2.7	0.8	-0.3	0.1	1.1	1.6	0.5	-0.2	1.0	0.2	0.7	-1.1	1.0	0.6	0.3	0.2	1.2	0.6	0.5
Bipolar Disorder (2011)	0.6	0.6	2.6	0.2	1.6	-0.1	-1.2	0.2	0.6	0.5	0.6	0.6	0.9	0.7	0.8	0.1	1.1	0.9	1.0	0.4	0.7
Ulcerative Colitis	0.6	0.9	2.6	0.8	0.3	0.2	-0.6	0.5	0.6	0.0	1.6	1.3	0.9	1.3	0.3	1.2	1.0	1.3	0.6	1.3	0.2
Height	0.6	10.9	48.7	-3.2	-3.2	-6.5	-7.0	-0.9	-4.2	0.8	-2.7	-1.8	0.6	-1.4	-1.8	-3.8	-1.8	1.3	-0.3	-0.1	-5.5
Lung FVC	0.6	3.3	17.6	0.2	2.6	-1.5	0.3	-0.6	1.2	1.1	0.1	2.0	2.4	1.3	1.4	0.1	3.2	4.2	1.5	1.4	0.7
Severe depression (siblings)	0.6	0.7	2.4	-1.5	-0.3	-1.5	-0.3	-1.1	-1.1	0.4	-0.9	-0.5	-0.7	0.1	-0.9	-1.6	-0.0	-0.2	0.1	-0.7	-0.6
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	3.1	-0.8	-0.4	1.2	0.8	0.5	0.2	-0.9	0.1	-1.1	-1.4	-0.4	-0.5	-0.5	-0.6	-1.6	-0.8	-1.7	0.5
Fluid intelligence score	0.6	1.3	4.4	-0.2	-1.6	0.2	-0.7	-1.1	-1.0	0.3	-0.9	-0.9	-1.4	-2.1	-1.0	-0.4	-1.9	-1.6	-1.6	-0.6	-0.7
Illnesses of mother	0.6	0.7	2.7	-0.0	1.6	-0.3	0.9	-1.1	0.3	0.1	-1.0	0.5	0.3	-1.7	1.0	-0.4	0.5	0.8	-0.6	-0.4	1.1
Standing height	0.6	6.3	30.2	-2.0	-2.2	-5.5	-5.2	0.3	-2.9	0.9	-1.2	-0.7	1.5	-1.4	-0.7	-2.5	-1.3	1.6	-0.3	0.7	-4.5
Length of working week for main job	0.6	0.7	1.9	-0.9	-1.2	-1.4	0.3	-0.3	-1.1	0.4	-0.2	-0.7	-0.2	-0.7	-0.8	-1.2	-0.9	-0.6	-0.4	-0.4	-1.3
Pulse wave reflection index	0.6	0.7	2.4	-0.6	-1.2	-1.6	-0.9	-0.5	-1.0	0.0	-1.2	-0.2	-0.1	-0.8	-0.7	-0.6	-0.7	0.5	-0.4	0.4	-1.5
Leg fat percentage (right)	0.6	2.1	7.2	-0.8	-2.4	-2.4	-2.2	-0.4	-2.0	1.0	-0.3	-0.9	0.4	-0.5	-1.4	-1.1	-0.9	-0.4	1.4	0.8	-2.7
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.3	-0.5	-0.7	0.9	-0.5	-0.1	-0.5	-0.7	-0.5	-1.3	-1.3	-0.9	-0.8	-0.2	-1.1	-1.5	-0.2	-0.9	-0.0
Mean time to correctly identify matches	0.6	1.1	3.1	0.3	0.5	-1.1	-0.4	0.7	0.4	1.2	0.4	1.0	1.7	1.1	1.1	0.4	1.5	1.7	1.7	1.2	0.0
Age at last live birth	0.6	0.8	3.1	0.2	-0.1	1.8	-0.1	-0.8	0.4	-0.6	-1.2	-0.5	-1.4	-0.6	-0.2	0.4	-0.8	-1.1	-1.6	-1.0	0.9
Commuting to job workplace: Car/motor vehicle	0.6	0.7	5.2	0.8	0.7	0.2	0.6	1.0	0.7	0.3	0.5	0.1	1.0	0.1	0.9	0.4	1.2	0.6	2.3	0.5	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.1	-0.5	0.1	1.2	1.2	-0.3	-0.1	-0.6	0.3	-0.8	-1.2	0.1	-0.5	-0.2	-0.7	-1.5	-1.0	-1.3	0.4
Eye problems/disorders: Cataract	0.6	0.7	1.3	-1.1	-1.0	-0.7	-0.4	-0.3	-0.9	-1.1	-1.1	-0.8	-0.7	0.4	-0.7	-0.8	-1.1	-0.7	-0.9	-0.6	-1.2
Eye problems/disorders: Glaucoma	0.6	0.7	4.1	0.2	-0.5	-1.1	-0.6	0.6	0.2	1.0	0.3	0.6	1.1	2.0	0.6	-0.0	0.9	1.0	0.7	0.7	-0.4
Medication: Blood pressure	0.6	1.1	3.3	1.8	0.2	1.3	0.8	0.9	1.0	1.7	1.4	1.1	0.3	-0.5	0.6	1.8	0.2	-0.1	0.6	1.4	1.0
Medication: Lisinopril	0.6	0.7	3.4	0.8	-0.7	-1.3	-1.9	-0.2	-0.3	0.5	-0.1	0.7	0.6	0.4	-0.3	0.2	0.3	1.5	0.3	1.2	-1.1
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.3	-0.6	-2.0	-0.9	-2.1	-0.5	-1.4	1.7	-1.1	-0.5	-0.9	-1.5	-0.8	-0.3	-1.9	-1.1	-1.4	0.0	-1.5
Age at First Birth	0.5	0.7	2.0	0.9	1.3	0.4	0.9	0.6	1.1	0.3	-0.0	0.9	0.9	0.5	1.4	0.9	1.0	1.1	0.2	0.5	1.0
Crohns Disease (2012)	0.5	0.8	1.5	-0.8	-0.9	-0.7	-1.1	-1.0	-1.0	-1.2	-0.9	-1.2	-0.7	-0.0	-0.8	-1.1	-0.8	-0.8	-0.2	-0.9	-0.8
Type 2 Diabetes (T2D) (2018)	0.5	0.9	3.5	-1.2	-1.4	-0.9	-1.9	-0.5	-1.1	-0.6	-0.6	-0.8	-0.6	0.7	-0.7	-1.0	-0.7	-0.7	-0.5	-0.7	-1.1
Hand grip strength (right)	0.5	1.3	3.7	0.5	0.6	-1.5	-1.4	1.8	0.4	1.6	1.0	0.8	1.5	0.8	1.1	0.3	0.8	1.9	0.4	0.9	-0.7
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.5	0.7	1.1	1.1	1.2	0.8	1.1	-0.6	0.6	0.4	0.1	0.0	1.1	0.8	0.2	0.2	-1.0	-0.4	1.2
Forced expiratory volume in 1-second (FEV1)	0.5	1.5	8.2	0.6	1.3	-1.1	-0.6	0.4	0.7	1.0	0.7	1.3	1.9	0.5	0.5	0.5	1.7	2.9	1.3	1.6	-0.5
Impedance of arm (left)	0.5	2.5	5.9	1.8	1.0	0.1	0.9	0.4	1.3	1.9	0.4	2.1	1.8	1.5	1.5	2.0	1.8	2.2	1.9	2.4	1.0
Comparative body size at age 10	0.5	1.3	5.0	-1.3	-1.8	-1.2	-2.2	-0.7	-1.4	0.2	-1.5	-0.7	-0.7	-0.4	-1.5	-0.8	-0.9	-0.2	-0.2	0.1	-1.8
Eye problems/disorders: None of the above	0.5	0.5	2.2	0.9	1.5	1.2	0.3	-0.3	0.7	0.5	0.2	0.4	-0.2	-1.3	0.4	0.4	0.4	-0.1	-0.0	-0.2	1.4
Friendships satisfaction	0.5	0.6	2.9	-0.1	-1.1	-1.7	-0.8	0.1	-0.8	1.2	-0.6	-0.2	0.1	0.6	-0.3	-0.8	-0.4	-0.1	0.3	0.2	-1.1
Illnesses of father: None of the above (group 1)	0.5	0.6	1.9	1.3	1.4	1.2	0.5	0.5	1.2	-0.0	0.6	0.5	0.3	-0.4	0.9	0.8	0.7	0.2	0.3	0.1	1.3
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.8	-0.2	-1.3	-0.3	-1.3	-0.5	-0.9	0.0	-0.1	-0.8	-0.3	-0.7	-1.3	-0.3	-1.0	-0.7	0.2	0.2	-1.3
Medication: Bendroflumethiazide	0.5	0.7	4.1	0.2	-1.1	1.0	-0.2	-0.1	-0.3	-0.5	0.1	-1.0	-1.0	-2.0	-0.7	0.1	-1.3	-1.4	-0.4	-0.5	-0.1
Ever smoked	0.5	0.9	3.8	-0.9	-0.9	-0.3	-1.0	-1.9	-0.9	-0.8	-1.6	-1.0	-1.1	-0.4	-1.1	-0.9	-0.7	-0.4	-0.1	-0.7	-0.5
Leg fat percentage (left)	0.5	2.0	6.3	-0.8	-2.3	-2.4	-2.2	-0.5	-2.0	0.9	-0.4	-0.9	0.3	-0.5	-1.4	-1.3	-0.9	-0.5	1.3	0.6	-2.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.3	0.0	0.7	-1.3	-0.5	0.4	0.1	0.6	0.7	0.7	1.1	0.6	0.5	-0.0	0.9	1.5	0.7	0.8	-0.5
Supplements: Calcium	0.5	0.6	2.8	-0.0	0.3	0.8	1.7	-0.1	-0.0	-1.0	-0.1	-1.0	-0.9	-0.9	-0.7	-0.5	-0.5	-1.1	-0.0	-1.0	0.2
Lupus	0.4	0.6	1.7	-0.4	0.5	1.1	1.1	-0.2	0.6	-0.6	-0.2	-0.6	-1.1	-0.7	-0.5	-0.4	-0.4	-0.8	-1.3	-1.3	0.6
Primary Biliary Cirrhosis	0.4	0.6	2.4	0.7	-0.2	-0.2	-0.8	1.5	0.3	-0.1	1.5	0.4	1.1	0.6	0.7	0.8	0.0	0.3	0.6	1.0	-0.5
Relative age of first facial hair	0.4	0.8	1.7	-1.2	-1.2	-1.1	-1.1	-1.0	-1.1	-0.3	-0.8	-0.7	-0.5	0.5	-1.3	-1.3	0.0	-0.2	0.4	-0.6	-1.1
Medication: Metformin	0.4	0.5	1.8	-0.7	-1.4	-0.6	-0.8	0.2	-0.7	-1.0	-0.3	-0.6	-0.3	1.3	-0.7	-0.5	-0.2	-0.3	0.3	-0.2	-1.1
Qualifications: None of the above	0.4	0.9	4.1	0.2	0.1	-1.7	-1.0	-0.5	-0.4	0.1	0.8	0.6	1.6	0.1	0.1	-0.4	0.8	2.0	0.9	1.0	-0.9
Impedance of arm (right)	0.4	1.8	5.0	1.5	0.9	0.2	0.9	0.0	1.0	1.5	0.2	1.9	1.5	1.4	1.1	1.8	1.4	1.8	1.5	2.2	0.8
Father’s age at death	0.4	0.6	1.9	-0.3	0.7	1.3	1.4	-0.9	0.5	-0.6	-1.1	-0.2	-1.0	0.6	-0.3	0.1	0.1	-0.3	-0.7	-0.7	1.1
Birth weight	0.4	0.8	7.6	-0.5	0.8	-0.2	-0.8	-0.2	-0.4	-0.7	-1.3	-1.0	-0.4	-2.8	0.0	-0.9	-0.5	-0.7	0.0	-1.0	0.2
Loneliness, isolation	0.4	0.5	2.1	-0.7	-0.2	-0.7	-0.6	-1.5	-0.8	-0.5	-0.8	-0.3	-0.9	-0.4	-0.9	-0.9	-0.5	-0.3	-0.9	-0.6	-0.5
Ever had bowel cancer screening	0.4	0.5	2.0	-1.0	0.0	-1.3	-0.2	-0.2	-0.5	-0.3	-0.8	-0.8	0.0	0.4	-0.2	-1.4	0.7	0.7	0.9	-0.9	-0.4
Qualifications: nursing, teaching	0.4	0.6	1.7	0.7	-0.3	1.3	-0.3	0.4	0.4	1.3	-0.5	0.4	-0.9	-0.9	-0.1	1.3	-0.8	-0.9	-0.9	0.6	0.4
Mineral and other dietary supplements	0.4	0.6	2.4	0.6	-0.6	1.3	0.2	1.5	0.5	-0.7	1.3	-0.4	-0.2	0.5	0.2	0.5	-0.5	-1.1	-0.3	-0.5	0.4
Osteoarthritis (self-reported)	0.4	0.6	2.7	-0.2	-1.1	-1.0	-1.6	-0.5	-0.9	0.5	-0.8	-0.2	-0.1	0.3	-0.7	-0.1	-0.5	0.3	0.2	0.6	-1.3
Average weekly champagne plus white wine intake	0.4	0.5	3.0	0.4	1.0	1.7	0.9	-0.1	0.7	-0.1	-0.0	0.2	-0.6	-0.1	0.5	0.7	0.1	-0.6	-0.7	-0.5	1.4
Bipolar Disorder (2018)	0.3	0.4	1.3	-0.6	0.7	-0.7	-1.1	-0.7	-0.1	0.5	-0.6	-0.1	0.2	-0.9	0.2	-1.0	0.8	0.4	0.9	-0.5	0.6
Coronary Artery Disease (CAD)	0.3	0.3	1.0	-0.8	-0.4	-0.5	0.6	-0.4	-0.5	-0.8	-0.8	-0.7	-0.0	-0.5	0.1	-1.0	-0.1	-0.0	-0.1	-0.8	-0.1
Rheumatoid Arthritis	0.3	0.4	1.5	-0.1	-0.9	-0.3	-0.6	1.0	-0.2	0.2	0.9	0.2	-0.1	0.8	0.1	0.2	-0.8	-0.9	-1.2	0.2	-0.7
Type 2 Diabetes (T2D) (2012)	0.3	0.4	2.3	0.8	-0.1	0.7	0.2	-0.1	0.4	0.1	0.8	0.5	0.0	-1.3	0.2	0.3	-0.6	-0.2	-1.5	0.1	0.1
Waist Hip Ratio (WHR)	0.3	1.2	4.4	0.8	1.3	0.4	1.7	0.6	1.0	0.3	0.9	0.7	0.8	2.1	1.1	0.7	1.5	0.8	1.4	0.3	1.2
Cardiovascular Disease	0.3	1.1	5.8	0.7	-2.4	-0.5	-1.4	0.4	-0.8	1.4	-0.1	-0.3	0.1	-1.5	-0.0	0.8	-1.6	-0.6	0.1	1.0	-1.3
Lung FEV1/FVC ratio	0.3	1.4	5.1	-0.0	-1.3	1.3	0.1	-0.8	-0.5	-2.2	-0.2	-1.0	-1.7	-1.7	-2.2	0.1	-1.4	-1.5	-0.2	-0.3	-0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.4	-0.1	-0.3	0.6	1.2	-0.1	0.1	-0.6	-0.2	-0.5	-0.8	-0.5	-0.4	-0.2	-0.4	-0.9	-0.5	-0.8	0.3
Serious illness, injury or assault to yourself	0.3	0.4	1.8	-0.3	-1.0	-0.6	-1.3	-0.5	-0.6	-0.4	0.3	-0.1	-0.2	1.0	-0.6	-0.2	-0.1	-0.1	0.5	0.2	-0.8
Forced vital capacity (FVC)	0.3	1.0	5.9	-0.1	0.6	-1.7	-1.6	-0.0	-0.1	0.4	-0.0	0.4	1.4	-0.1	0.1	-0.4	1.0	2.4	0.6	0.8	-1.2
Diabetes (self-reported)	0.3	0.4	1.4	-0.2	-0.8	-1.2	-1.2	-0.1	-0.3	0.1	0.1	0.7	0.6	1.2	0.2	-0.0	0.2	0.9	-0.3	0.7	-0.8
Time employed in main current job	0.3	0.3	1.4	0.4	0.7	-0.2	0.4	0.3	0.5	0.6	1.2	0.7	0.8	0.1	0.5	0.1	0.6	0.6	0.3	0.4	0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.7	4.5	-0.6	-0.3	0.7	-0.2	-0.4	0.1	-0.4	-1.4	-0.3	-1.3	-0.6	-0.0	0.1	-1.2	-1.1	-2.1	-0.9	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.3	-0.7	0.7	-0.8	-0.4	0.2	0.1	1.1	0.3	-0.0	0.3	-0.3	0.3	-1.1	0.6	0.1	0.2	-0.7	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	5.3	0.0	0.6	-1.6	-1.5	-0.1	-0.1	0.9	0.0	0.7	1.6	-0.0	0.2	0.0	0.8	2.3	0.8	1.3	-1.2
Hair/balding pattern: Pattern 4	0.3	0.7	2.3	-0.3	-1.0	-1.4	-1.4	-0.1	-0.8	0.9	-0.6	0.1	0.4	-0.8	-0.2	-0.2	-0.8	0.6	-0.7	0.6	-1.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.0	-0.3	1.3	1.2	1.4	-0.6	0.6	-0.7	-0.1	0.3	-0.6	0.8	-0.2	0.2	0.1	-0.3	-1.1	-0.5	1.0
Forced vital capacity (FVC), Best measure	0.3	1.3	5.1	-1.0	-0.0	-2.2	-2.1	-0.9	-1.0	0.2	-1.0	-0.3	0.8	-0.7	-0.5	-1.2	-0.1	1.7	-0.2	0.2	-1.9
Alcohol intake frequency.	0.3	0.7	1.9	-0.6	-0.8	-0.7	-0.6	1.4	-0.7	0.7	0.9	-0.9	-0.1	-0.0	-0.8	-0.9	-0.3	-1.1	1.3	-0.3	-0.9
Average weekly beer plus cider intake	0.3	0.4	1.3	-0.2	-0.1	0.5	0.3	-1.0	-0.1	-0.3	-0.9	-0.9	-0.8	-0.4	-0.1	-0.6	-0.4	-0.8	-0.1	-1.2	0.5
Age started oral contraceptive pill	0.3	0.4	1.7	1.0	0.2	-0.3	-0.5	1.1	0.4	0.5	1.3	0.8	0.5	0.5	0.3	0.6	0.5	0.7	0.3	0.9	-0.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.1	0.9	-0.1	-0.2	-0.2	0.6	0.1	1.1	0.9	0.4	0.9	-0.5	0.5	0.5	0.3	0.3	0.9	0.8	-0.0
Blood Red Count	0.2	1.9	8.6	-1.5	-0.3	-2.9	0.9	-2.1	-1.6	1.9	-1.6	0.8	0.9	0.6	-0.3	-1.0	0.0	1.4	-0.2	1.2	-1.6
Heel T-Score	0.2	2.0	10.0	-1.1	-1.1	-3.2	-1.2	-1.0	-1.3	2.3	-1.6	0.6	1.2	-0.7	0.1	-0.8	0.2	1.8	0.7	1.3	-1.7
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.7	0.1	-0.7	-0.0	0.6	-0.7	-0.6	-0.3	-0.1	-0.3	-0.3	-0.3	-0.8	-0.0	-0.5	-0.2	0.1	0.2	-0.6
Medication: Atenolol	0.2	0.3	1.1	-0.1	-1.0	-0.5	-1.1	0.6	-0.4	0.4	0.4	0.0	0.1	0.6	-0.3	0.3	-0.4	0.0	-0.0	0.6	-0.9
Sitting height	0.2	1.5	8.3	-0.5	-0.6	-2.9	-2.5	1.0	-0.7	0.6	0.2	0.2	1.5	-0.6	0.6	-1.1	-0.0	1.6	-0.3	0.4	-1.8
Heart attack	0.2	0.3	1.2	0.7	-0.2	-0.4	-0.4	0.4	-0.0	1.1	0.7	0.3	0.8	-0.5	0.4	0.4	0.2	0.3	0.7	0.8	-0.2
Illnesses of siblings	0.2	0.3	1.2	0.0	1.1	0.9	0.3	0.5	0.7	-0.4	-0.3	0.0	-0.3	-0.2	0.7	0.3	0.2	-0.4	-0.3	-0.6	1.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	2.4	-0.7	-0.2	0.2	0.9	-0.6	-0.1	-0.1	-1.6	-0.1	-1.1	-0.2	-0.4	-0.2	-0.5	-0.7	-0.8	-0.5	0.2
Medication: Omeprazole	0.2	0.2	0.7	0.3	0.5	-0.7	-0.2	0.5	0.0	0.4	0.6	0.6	0.6	0.5	0.2	0.1	0.5	0.8	0.2	0.5	-0.3
Leg pain on walking	0.2	0.2	1.4	0.3	-0.0	-0.4	-0.2	0.7	-0.1	1.1	0.2	-0.3	-0.0	-1.2	-0.4	-0.4	0.2	0.1	0.7	-0.1	-0.2
Average weekly red wine intake	0.2	0.3	0.7	0.7	0.6	0.6	0.4	0.5	0.7	0.4	0.2	0.5	0.1	-0.7	0.4	0.8	-0.3	0.3	-0.6	0.5	0.2
Diabetes diagnosed by doctor	0.2	0.3	1.6	0.1	-0.6	-0.5	-0.9	0.5	0.0	0.1	0.7	0.6	0.5	1.3	0.3	0.3	0.3	0.5	-0.1	0.6	-0.5
Breast cancer (self-reported)	0.2	0.2	1.2	-0.2	0.0	-0.8	-1.1	-0.1	-0.3	-0.2	0.2	-0.1	0.4	-0.7	0.1	-0.6	0.4	0.5	0.7	-0.1	-0.3
Illnesses of father: High blood pressure	0.2	0.3	1.6	0.3	0.6	0.6	1.2	0.0	0.5	0.4	-0.2	0.1	0.1	0.5	0.3	0.4	-0.4	0.0	-1.3	-0.1	0.0
Irritable Bowel Disease (IBD)	0.1	0.3	1.1	0.5	-0.7	-0.2	-0.9	-0.2	-0.1	-0.5	0.7	0.6	0.3	1.0	-0.4	0.5	0.4	0.6	0.4	0.9	-0.5
LDL Cholesterol	0.1	0.2	1.2	-0.3	-0.5	0.2	-0.4	-0.3	-0.3	-1.1	-0.4	-0.4	-0.3	-0.2	-0.5	-0.2	-0.6	-0.4	-0.1	-0.0	-0.5
Triglycerides	0.1	0.1	0.4	0.2	-0.4	-0.0	0.6	0.0	-0.2	-0.2	-0.1	-0.3	0.2	0.2	-0.3	-0.2	-0.4	-0.5	0.5	0.3	-0.4
Tanning	0.1	1.0	10.6	0.9	-0.6	0.4	0.3	1.3	1.0	0.9	-0.0	0.3	0.1	3.2	0.1	0.7	1.0	0.2	1.3	0.4	0.2
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	-0.1	-0.1	-0.2	-0.4	0.5	-0.0	0.2	-0.0	-0.6	-0.1	-0.5	-0.2	-0.3	-0.0	-0.3	0.6	-0.4	-0.1
Prospective memory result	0.1	0.2	1.0	-0.2	0.5	-0.2	-0.4	1.0	0.3	-0.4	0.8	-0.2	0.4	-0.3	0.2	-0.4	0.3	0.2	0.1	-0.3	-0.0
Family relationship satisfaction	0.1	0.2	0.8	0.5	0.4	-0.9	-0.3	-0.4	-0.1	0.5	-0.1	0.4	0.2	-0.4	-0.2	-0.4	0.4	0.6	0.2	0.3	-0.3
Osteoporosis (self-reported)	0.1	0.1	0.6	-0.2	0.5	-0.3	0.6	-0.3	-0.1	-0.7	0.2	-0.1	0.1	-0.1	-0.1	-0.2	0.2	0.3	0.1	-0.0	-0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.6	1.8	1.0	0.9	1.4	0.3	-0.9	0.8	1.0	-0.5	0.7	-0.6	-0.9	-0.2	0.6	0.2	0.3	-1.1	0.1	0.9

Hub : Genes

MMAB

Models

Trait associations