[Hub]/) : Traits : Leg predicted mass (right) :

chr14:72,695,406-74,192,791

Best TWAS P=5.84e-10 · Best GWAS P=6.16e-08 conditioned to 0.755

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DCAF4 0.23 0.07 enet 30 0.13 4.3e-07 4.5 5.6 1.7e-08 0.77 0.01 0.99 FALSE
2 GTEx Colon Sigmoid DCAF4 0.30 0.10 lasso 9 0.11 1.3e-04 5.4 5.9 3.3e-09 0.89 0.01 0.96 FALSE
3 GTEx Esophagus Gastroesophageal Junction DCAF4 0.18 0.01 enet 10 0.06 3.0e-03 5.4 6.2 5.8e-10 0.85 0.01 0.92 TRUE
4 GTEx Esophagus Mucosa ZFYVE1 0.10 0.00 lasso 7 0.00 2.0e-01 5.4 6.0 2.4e-09 0.80 0.02 0.91 FALSE
5 GTEx Pancreas DCAF4 0.20 0.15 lasso 4 0.14 2.4e-06 5.4 5.2 1.9e-07 0.98 0.00 0.99 FALSE
6 GTEx Spleen DCAF4 0.47 0.12 enet 10 0.19 1.5e-05 4.4 5.6 2.4e-08 0.75 0.03 0.95 FALSE
7 NTR Blood DCAF4 0.04 0.03 lasso 6 0.03 6.5e-09 5.4 5.5 3.7e-08 0.96 0.00 1.00 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DCAF4 0.04 0.02 blup 83 0.03 1.2e-04 4.4 5.2 2.1e-07 0.76 0.01 0.98 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma DPF3 0.10 0.02 blup 210 0.07 1.9e-07 -2.8 -5.2 1.5e-07 -0.56 0.38 0.54 FALSE