Best TWAS P=1.41e-09 · Best GWAS P=2.4e-07 conditioned to 0.778
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C15orf65 | 0.16 | 0.02 | lasso | 11 | 0.03 | 2.2e-03 | -5.1 | -5.3 | 9.6e-08 | 0.83 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Muscle Skeletal | C15orf65 | 0.07 | 0.00 | enet | 18 | 0.01 | 4.1e-02 | -3.3 | -5.5 | 4.9e-08 | 0.68 | 0.02 | 0.84 | FALSE |
| 3 | GTEx | Uterus | C15orf65 | 0.33 | 0.02 | lasso | 13 | 0.02 | 1.1e-01 | -5.1 | -6.1 | 1.4e-09 | 0.88 | 0.03 | 0.51 | TRUE |
| 4 | METSIM | Adipose | C15orf65 | 0.09 | 0.03 | bslmm | 438 | 0.06 | 5.1e-09 | -3.8 | -5.6 | 2.8e-08 | 0.71 | 0.02 | 0.98 | FALSE |