[Hub]/) : Traits : Leg predicted mass (right) : ← →

chr16:71,070,698-72,540,539

Best TWAS P=9.75e-11 · Best GWAS P=7.28e-13 conditioned to 7.62e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MARVELD3 0.07 0.05 lasso 3 0.09 5.7e-11 -6.4 -5.7 1.3e-08 0.43 0.38 0.62 FALSE
2 CommonMind Brain Pre-frontal Cortex PHLPP2 0.04 0.01 bslmm 456 0.02 4.7e-04 -5.1 -6.5 9.7e-11 0.41 0.38 0.53 TRUE
3 GTEx Adipose Subcutaneous AP1G1 0.08 0.05 enet 17 0.06 1.0e-05 -5.7 -5.1 2.9e-07 0.42 0.40 0.58 FALSE
4 GTEx Adrenal Gland AP1G1 0.22 0.06 enet 25 0.14 8.0e-06 -6.2 -6.2 5.5e-10 0.46 0.30 0.64 FALSE
5 GTEx Artery Aorta AP1G1 0.10 0.09 lasso 2 0.07 1.3e-04 -5.2 -5.2 1.8e-07 0.43 0.36 0.33 FALSE
6 GTEx Artery Tibial AP1G1 0.07 0.06 lasso 6 0.06 1.0e-05 -3.5 -5.3 9.1e-08 0.51 0.49 0.50 FALSE
7 GTEx Testis PHLPP2 0.29 0.38 enet 20 0.37 3.0e-17 -6.4 6.2 4.6e-10 -0.56 0.36 0.64 FALSE
8 YFS Blood PHLPP2 0.04 0.03 bslmm 459 0.05 5.5e-16 -6.2 5.6 1.9e-08 -0.42 0.40 0.60 FALSE
9 The Cancer Genome Atlas Esophageal Carcinoma PHLPP2 0.18 0.03 blup 67 0.07 2.9e-03 -6.4 -5.5 3.2e-08 0.46 0.06 0.15 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma AP1G1 0.03 0.03 lasso 4 0.02 2.1e-03 -3.5 -5.2 1.9e-07 0.46 0.02 0.86 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma AP1G1 0.11 0.02 enet 27 0.04 1.2e-04 3.0 -5.5 4.2e-08 0.41 0.08 0.24 FALSE