Best TWAS P=6.37e-08 · Best GWAS P=1.23e-09 conditioned to 4.65e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | NFATC3 | 0.04 | 0.01 | lasso | 4 | 0.01 | 4.1e-02 | 5.1 | -5.4 | 6.4e-08 | -0.32 | 0.18 | 0.44 | TRUE |
| 2 | GTEx | Thyroid | PLA2G15 | 0.06 | 0.04 | enet | 5 | 0.04 | 5.7e-04 | 5.6 | 5.3 | 9.1e-08 | 0.38 | 0.10 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NFATC3 | 0.11 | 0.04 | enet | 4 | 0.04 | 2.8e-05 | 5.4 | -5.3 | 1.2e-07 | -0.36 | 0.00 | 0.99 | FALSE |