Best TWAS P=5.69e-09 · Best GWAS P=1.17e-10 conditioned to 0.00407
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMG6 | 0.03 | 0.01 | blup | 144 | 0.01 | 0.00478 | 5.7 | 5.8 | 5.7e-09 | 0.83 | 0.08 | 0.67 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SMG6 | 0.08 | 0.05 | blup | 144 | 0.07 | 0.00013 | 6.4 | 5.6 | 1.9e-08 | 0.85 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | SRR | 0.16 | 0.03 | blup | 61 | 0.02 | 0.08720 | -3.0 | 5.3 | 9.1e-08 | 0.82 | 0.03 | 0.24 | FALSE |